MCID: EXT020
MIFTS: 23

External Pathological Resorption

Categories: Oral diseases

Aliases & Classifications for External Pathological Resorption

MalaCards integrated aliases for External Pathological Resorption:

Name: External Pathological Resorption 12 15
External Resorption of Tooth 71

Classifications:



External Ids:

Disease Ontology 12 DOID:14529
ICD9CM 34 521.42
SNOMED-CT 67 41918006
ICD10 32 K03.3
UMLS 71 C0266878

Summaries for External Pathological Resorption

MalaCards based summary : External Pathological Resorption, also known as external resorption of tooth, is related to scorpion envenomation and physiological polycythemia. An important gene associated with External Pathological Resorption is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Human T-cell leukemia virus 1 infection and IL-17 Family Signaling Pathways.

Related Diseases for External Pathological Resorption

Diseases in the Internal Pathological Resorption family:

External Pathological Resorption

Diseases related to External Pathological Resorption via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 447)
# Related Disease Score Top Affiliating Genes
1 scorpion envenomation 10.0 TNF IL6
2 physiological polycythemia 10.0 TNF IL6
3 idiopathic anterior uveitis 10.0 TNF IL6
4 uveitis 10.0 TNF IL6
5 streptococcal toxic-shock syndrome 10.0 TNF IL6
6 angioimmunoblastic lymphadenopathy with dysproteinemia 10.0 TNF IL6
7 cardiogenic shock 10.0 TNF IL6
8 null-cell leukemia 10.0 TNF IL6
9 ulcer of lower limbs 10.0 TNF IL6
10 systemic onset juvenile idiopathic arthritis 10.0 TNF IL6
11 posterior urethral valves 10.0 TNF IL6
12 stachybotrys chartarum 10.0 TNF IL6
13 bacterial conjunctivitis 10.0 TNF IL6
14 conjunctivitis 10.0 TNF IL6
15 tracheitis 10.0 TNF IL6
16 carbuncle 10.0 TNF IL6
17 post-transplant lymphoproliferative disease 10.0 TNF IL6
18 superficial basal cell carcinoma 10.0 TNF IL6
19 hypopyon 10.0 TNF IL6
20 enterocolitis 10.0 TNF IL6
21 eales disease 10.0 TNF IL6
22 tenosynovitis 10.0 TNF IL6
23 synovitis 10.0 TNF IL6
24 aortitis 10.0 TNF IL6
25 coronary aneurysm 10.0 TNF IL6
26 chondromalacia 10.0 TNF IL6
27 anthracosis 10.0 TNF IL6
28 progressive myoclonus epilepsy 8 10.0 TNF IL6
29 lung abscess 10.0 TNF IL6
30 heart aneurysm 10.0 TNF IL6
31 neurotic disorder 10.0 TNF IL6
32 peptic esophagitis 10.0 TNF IL6
33 esophagitis 10.0 TNF IL6
34 scleral disease 10.0 TNF IL6
35 gingival recession 10.0 TNF IL6
36 bursitis 10.0 TNF IL6
37 retinitis pigmentosa 55 10.0 TNF IL6
38 combat disorder 10.0 TNF IL6
39 laryngitis 10.0 TNF IL6
40 salpingitis 10.0 TNF IL6
41 vaginal discharge 10.0 TNF IL6
42 irritant dermatitis 10.0 TNF IL6
43 iritis 10.0 TNF IL6
44 background diabetic retinopathy 10.0 TNF IL6
45 iridocyclitis 10.0 TNF IL6
46 chorioretinitis 10.0 TNF IL6
47 periapical periodontitis 10.0 TNF IL6
48 periodontitis 10.0 TNF IL6
49 dental pulp disease 10.0 TNF IL6
50 trichomoniasis 10.0 TNF IL6

Graphical network of the top 20 diseases related to External Pathological Resorption:



Diseases related to External Pathological Resorption

Symptoms & Phenotypes for External Pathological Resorption

Drugs & Therapeutics for External Pathological Resorption

Search Clinical Trials , NIH Clinical Center for External Pathological Resorption

Genetic Tests for External Pathological Resorption

Anatomical Context for External Pathological Resorption

Publications for External Pathological Resorption

Articles related to External Pathological Resorption:

# Title Authors PMID Year
1
Trial shows partial caries removal is an effective technique in primary molars. 61
25343394 2014
2
Dental pulp and periodontal ligament cells support osteoclastic differentiation. 61
19641147 2009

Variations for External Pathological Resorption

Expression for External Pathological Resorption

Search GEO for disease gene expression data for External Pathological Resorption.

Pathways for External Pathological Resorption

Pathways related to External Pathological Resorption according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1 12.03 TNF IL6
2
Show member pathways
12.02 TNF IL6
3
Show member pathways
12.02 TNF IL6
4
Show member pathways
12.01 TNF IL6
5
Show member pathways
11.95 TNF IL6
6
Show member pathways
11.94 TNF IL6
7 11.93 TNF IL6
8 11.92 TNF IL6
9
Show member pathways
11.9 TNF IL6
10 11.88 TNF IL6
11
Show member pathways
11.87 TNF IL6
12 11.86 TNF IL6
13 11.78 TNF IL6
14 11.76 TNF IL6
15 11.72 TNF IL6
16 11.7 TNF IL6
17 11.68 TNF IL6
18 11.67 TNF IL6
19
Show member pathways
11.66 TNF IL6
20 11.62 TNF IL6
21 11.61 TNF IL6
22 11.59 TNF IL6
23 11.56 TNF IL6
24
Show member pathways
11.46 TNF IL6
25 11.46 TNF IL6
26 11.44 TNF IL6
27 11.38 TNF IL6
28
Show member pathways
11.35 TNF IL6
29 11.34 TNF IL6
30 11.28 TNF IL6
31 11.22 TNF IL6
32 11.19 TNF IL6
33 11.17 TNF IL6
34 11.14 TNF IL6
35 11.09 TNF IL6
36 10.97 TNF IL6
37 10.91 TNF IL6
38 10.83 TNF IL6
39 10.75 TNF IL6
40 10.62 TNF IL6
41 10.3 TNF IL6
42 9.9 TNF IL6

GO Terms for External Pathological Resorption

Biological processes related to External Pathological Resorption according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 cellular response to lipopolysaccharide GO:0071222 9.61 TNF IL6
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.61 TNF IL6
3 positive regulation of DNA-binding transcription factor activity GO:0051091 9.6 TNF IL6
4 defense response to Gram-positive bacterium GO:0050830 9.59 TNF IL6
5 positive regulation of interleukin-6 production GO:0032755 9.58 TNF IL6
6 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.58 TNF IL6
7 regulation of insulin secretion GO:0050796 9.57 TNF IL6
8 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.56 TNF IL6
9 response to glucocorticoid GO:0051384 9.55 TNF IL6
10 positive regulation of smooth muscle cell proliferation GO:0048661 9.54 TNF IL6
11 positive regulation of interleukin-8 production GO:0032757 9.52 TNF IL6
12 humoral immune response GO:0006959 9.51 TNF IL6
13 positive regulation of interleukin-1 beta production GO:0032731 9.49 TNF IL6
14 negative regulation of fat cell differentiation GO:0045599 9.48 TNF IL6
15 positive regulation of chemokine production GO:0032722 9.46 TNF IL6
16 positive regulation of JAK-STAT cascade GO:0046427 9.43 TNF IL6
17 negative regulation of neurogenesis GO:0050768 9.4 TNF IL6
18 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.37 TNF IL6
19 positive regulation of glial cell proliferation GO:0060252 9.32 TNF IL6
20 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.26 TNF IL6
21 positive regulation of neuroinflammatory response GO:0150078 9.16 TNF IL6
22 negative regulation of lipid storage GO:0010888 8.96 TNF IL6
23 vascular endothelial growth factor production GO:0010573 8.62 TNF IL6

Sources for External Pathological Resorption

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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