MCID: EXT020
MIFTS: 24

External Pathological Resorption

Categories: Oral diseases

Aliases & Classifications for External Pathological Resorption

MalaCards integrated aliases for External Pathological Resorption:

Name: External Pathological Resorption 12 15
External Resorption of Tooth 71

Classifications:



External Ids:

Disease Ontology 12 DOID:14529
ICD9CM 34 521.42
SNOMED-CT 67 41918006 43079004
ICD10 32 K03.3
UMLS 71 C0266878

Summaries for External Pathological Resorption

MalaCards based summary : External Pathological Resorption, also known as external resorption of tooth, is related to scorpion envenomation and idiopathic anterior uveitis. An important gene associated with External Pathological Resorption is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Human T-cell leukemia virus 1 infection and IL-17 Family Signaling Pathways. Affiliated tissues include salivary gland.

Related Diseases for External Pathological Resorption

Diseases in the Internal Pathological Resorption family:

External Pathological Resorption

Diseases related to External Pathological Resorption via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 380)
# Related Disease Score Top Affiliating Genes
1 scorpion envenomation 9.9 TNF IL6
2 idiopathic anterior uveitis 9.9 TNF IL6
3 uveitis 9.9 TNF IL6
4 streptococcal toxic-shock syndrome 9.9 TNF IL6
5 angioimmunoblastic lymphadenopathy with dysproteinemia 9.9 TNF IL6
6 null-cell leukemia 9.9 TNF IL6
7 non-alcoholic steatohepatitis 9.9 TNF IL6
8 posterior urethral valves 9.9 TNF IL6
9 stachybotrys chartarum 9.9 TNF IL6
10 post-transplant lymphoproliferative disease 9.9 TNF IL6
11 aortitis 9.9 TNF IL6
12 retinitis pigmentosa 55 9.9 TNF IL6
13 transverse myelitis 9.9 TNF IL6
14 myelitis 9.9 TNF IL6
15 eales disease 9.9 TNF IL6
16 tenosynovitis 9.9 TNF IL6
17 synovitis 9.9 TNF IL6
18 anthracosis 9.9 TNF IL6
19 stromal keratitis 9.9 TNF IL6
20 pneumonic tularemia 9.9 TNF IL6
21 tularemia 9.9 TNF IL6
22 scleral disease 9.9 TNF IL6
23 lung abscess 9.9 TNF IL6
24 autoimmune disease of cardiovascular system 9.9 TNF IL6
25 chlamydia pneumonia 9.9 TNF IL6
26 chlamydia 9.9 TNF IL6
27 irritant dermatitis 9.9 TNF IL6
28 dermatitis 9.9 TNF IL6
29 iritis 9.9 TNF IL6
30 idiopathic neutropenia 9.9 TNF IL6
31 chorioretinitis 9.9 TNF IL6
32 iridocyclitis 9.9 TNF IL6
33 periapical periodontitis 9.9 TNF IL6
34 periodontitis 9.9 TNF IL6
35 dental pulp disease 9.9 TNF IL6
36 laryngitis 9.9 TNF IL6
37 bagassosis 9.9 TNF IL6
38 fungal meningitis 9.9 TNF IL6
39 meningitis 9.9 TNF IL6
40 trichomoniasis 9.9 TNF IL6
41 glossitis 9.9 TNF IL6
42 african tick-bite fever 9.9 TNF IL6
43 central nervous system vasculitis 9.9 TNF IL6
44 vasculitis 9.9 TNF IL6
45 orchitis 9.9 TNF IL6
46 chronic conjunctivitis 9.9 TNF IL6
47 conjunctivitis 9.9 TNF IL6
48 hantavirus hemorrhagic fever with renal syndrome 9.9 TNF IL6
49 tendinitis 9.9 TNF IL6
50 polyradiculopathy 9.9 TNF IL6

Graphical network of the top 20 diseases related to External Pathological Resorption:



Diseases related to External Pathological Resorption

Symptoms & Phenotypes for External Pathological Resorption

Drugs & Therapeutics for External Pathological Resorption

Search Clinical Trials , NIH Clinical Center for External Pathological Resorption

Genetic Tests for External Pathological Resorption

Anatomical Context for External Pathological Resorption

MalaCards organs/tissues related to External Pathological Resorption:

40
Salivary Gland

Publications for External Pathological Resorption

Articles related to External Pathological Resorption:

# Title Authors PMID Year
1
Trial shows partial caries removal is an effective technique in primary molars. 61
25343394 2014
2
Dental pulp and periodontal ligament cells support osteoclastic differentiation. 61
19641147 2009

Variations for External Pathological Resorption

Expression for External Pathological Resorption

Search GEO for disease gene expression data for External Pathological Resorption.

Pathways for External Pathological Resorption

Pathways related to External Pathological Resorption according to GeneCards Suite gene sharing:

(show all 45)
# Super pathways Score Top Affiliating Genes
1 12.04 TNF IL6
2
Show member pathways
12.03 TNF IL6
3
Show member pathways
12.02 TNF IL6
4
Show member pathways
12.02 TNF IL6
5 11.99 TNF IL6
6
Show member pathways
11.96 TNF IL6
7
Show member pathways
11.95 TNF IL6
8 11.93 TNF IL6
9 11.93 TNF IL6
10
Show member pathways
11.91 TNF IL6
11
Show member pathways
11.9 TNF IL6
12 11.88 TNF IL6
13
Show member pathways
11.88 TNF IL6
14 11.86 TNF IL6
15 11.77 TNF IL6
16
Show member pathways
11.76 TNF IL6
17
Show member pathways
11.74 TNF IL6
18 11.72 TNF IL6
19 11.71 TNF IL6
20 11.69 TNF IL6
21 11.68 TNF IL6
22 11.67 TNF IL6
23
Show member pathways
11.65 TNF IL6
24 11.61 TNF IL6
25 11.6 TNF IL6
26 11.59 TNF IL6
27 11.55 TNF IL6
28 11.46 TNF IL6
29 11.44 TNF IL6
30 11.41 TNF IL6
31
Show member pathways
11.35 TNF IL6
32 11.34 TNF IL6
33 11.28 TNF IL6
34 11.22 TNF IL6
35 11.19 TNF IL6
36 11.17 TNF IL6
37 11.14 TNF IL6
38 11.09 TNF IL6
39 10.97 TNF IL6
40 10.91 TNF IL6
41 10.83 TNF IL6
42 10.75 TNF IL6
43 10.62 TNF IL6
44 10.3 TNF IL6
45 9.9 TNF IL6

GO Terms for External Pathological Resorption

Biological processes related to External Pathological Resorption according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 cellular response to lipopolysaccharide GO:0071222 9.57 TNF IL6
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.56 TNF IL6
3 positive regulation of DNA-binding transcription factor activity GO:0051091 9.55 TNF IL6
4 defense response to Gram-positive bacterium GO:0050830 9.54 TNF IL6
5 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.52 TNF IL6
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.51 TNF IL6
7 response to glucocorticoid GO:0051384 9.49 TNF IL6
8 positive regulation of interleukin-6 production GO:0032755 9.48 TNF IL6
9 positive regulation of smooth muscle cell proliferation GO:0048661 9.46 TNF IL6
10 humoral immune response GO:0006959 9.43 TNF IL6
11 negative regulation of fat cell differentiation GO:0045599 9.4 TNF IL6
12 positive regulation of JAK-STAT cascade GO:0046427 9.37 TNF IL6
13 negative regulation of neurogenesis GO:0050768 9.32 TNF IL6
14 positive regulation of chemokine production GO:0032722 9.26 TNF IL6
15 positive regulation of glial cell proliferation GO:0060252 9.16 TNF IL6
16 positive regulation of neuroinflammatory response GO:0150078 8.96 TNF IL6
17 negative regulation of lipid storage GO:0010888 8.62 TNF IL6

Molecular functions related to External Pathological Resorption according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.62 TNF IL6

Sources for External Pathological Resorption

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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