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MCID: EXT020
MIFTS: 23

External Pathological Resorption

Categories: Oral diseases
Genes Related diseases Publications Pathways
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Aliases & Classifications for External Pathological Resorption

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MalaCards integrated aliases for External Pathological Resorption:

Name: External Pathological Resorption 12 15
External Resorption of Tooth 71

Classifications:

MalaCards categories:
Anatomical: Oral diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:14529
ICD9CM 34 521.42
SNOMED-CT 67 41918006
ICD10 32 K03.3
UMLS 71 C0266878
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Summaries for External Pathological Resorption

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MalaCards based summary : External Pathological Resorption, also known as external resorption of tooth, is related to scorpion envenomation and physiological polycythemia. An important gene associated with External Pathological Resorption is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Human T-cell leukemia virus 1 infection and IL-17 Family Signaling Pathways.

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Related Diseases for External Pathological Resorption

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Diseases in the Internal Pathological Resorption family:

External Pathological Resorption

Diseases related to External Pathological Resorption via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 447)
# Related Disease Score Top Affiliating Genes
1 scorpion envenomation 10.0 TNF IL6
2 physiological polycythemia 10.0 TNF IL6
3 idiopathic anterior uveitis 10.0 TNF IL6
4 uveitis 10.0 TNF IL6
5 streptococcal toxic-shock syndrome 10.0 TNF IL6
6 angioimmunoblastic lymphadenopathy with dysproteinemia 10.0 TNF IL6
7 cardiogenic shock 10.0 TNF IL6
8 null-cell leukemia 10.0 TNF IL6
9 ulcer of lower limbs 10.0 TNF IL6
10 systemic onset juvenile idiopathic arthritis 10.0 TNF IL6
11 posterior urethral valves 10.0 TNF IL6
12 stachybotrys chartarum 10.0 TNF IL6
13 bacterial conjunctivitis 10.0 TNF IL6
14 conjunctivitis 10.0 TNF IL6
15 tracheitis 10.0 TNF IL6
16 carbuncle 10.0 TNF IL6
17 post-transplant lymphoproliferative disease 10.0 TNF IL6
18 superficial basal cell carcinoma 10.0 TNF IL6
19 hypopyon 10.0 TNF IL6
20 enterocolitis 10.0 TNF IL6
21 eales disease 10.0 TNF IL6
22 tenosynovitis 10.0 TNF IL6
23 synovitis 10.0 TNF IL6
24 aortitis 10.0 TNF IL6
25 coronary aneurysm 10.0 TNF IL6
26 chondromalacia 10.0 TNF IL6
27 anthracosis 10.0 TNF IL6
28 progressive myoclonus epilepsy 8 10.0 TNF IL6
29 lung abscess 10.0 TNF IL6
30 heart aneurysm 10.0 TNF IL6
31 neurotic disorder 10.0 TNF IL6
32 peptic esophagitis 10.0 TNF IL6
33 esophagitis 10.0 TNF IL6
34 scleral disease 10.0 TNF IL6
35 gingival recession 10.0 TNF IL6
36 bursitis 10.0 TNF IL6
37 retinitis pigmentosa 55 10.0 TNF IL6
38 combat disorder 10.0 TNF IL6
39 laryngitis 10.0 TNF IL6
40 salpingitis 10.0 TNF IL6
41 vaginal discharge 10.0 TNF IL6
42 irritant dermatitis 10.0 TNF IL6
43 iritis 10.0 TNF IL6
44 background diabetic retinopathy 10.0 TNF IL6
45 iridocyclitis 10.0 TNF IL6
46 chorioretinitis 10.0 TNF IL6
47 periapical periodontitis 10.0 TNF IL6
48 periodontitis 10.0 TNF IL6
49 dental pulp disease 10.0 TNF IL6
50 trichomoniasis 10.0 TNF IL6

Graphical network of the top 20 diseases related to External Pathological Resorption:



Diseases related to External Pathological Resorption
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Symptoms & Phenotypes for External Pathological Resorption

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Drugs & Therapeutics for External Pathological Resorption

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Search Clinical Trials , NIH Clinical Center for External Pathological Resorption

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Genetic Tests for External Pathological Resorption

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Anatomical Context for External Pathological Resorption

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Publications for External Pathological Resorption

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Articles related to External Pathological Resorption:

# Title Authors PMID Year
1
Trial shows partial caries removal is an effective technique in primary molars. 61
25343394 2014
2
Dental pulp and periodontal ligament cells support osteoclastic differentiation. 61
19641147 2009
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Variations for External Pathological Resorption

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Expression for External Pathological Resorption

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Search GEO for disease gene expression data for External Pathological Resorption.
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Pathways for External Pathological Resorption

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Pathways related to External Pathological Resorption according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1
Human T-cell leukemia virus 1 infection 36
12.03 TNF IL6
2
IL-17 Family Signaling Pathways 64
Show member pathways
 12.02 TNF IL6
3
Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions 64
Show member pathways
 12.02 TNF IL6
4
Folate Metabolism 1
Show member pathways
 12.01 TNF IL6
5
Diseases associated with the TLR signaling cascade 65
Show member pathways
 11.95 TNF IL6
6
Dilated cardiomyopathy 36
Show member pathways
 11.94 TNF IL6
7
NOD-like receptor signaling pathway 36
11.93 TNF IL6
8
Tuberculosis 36
11.92 TNF IL6
9
C-type lectin receptor signaling pathway 36
Show member pathways
 11.9 TNF IL6
10
Colorectal Cancer Metastasis 63
11.88 TNF IL6
11
Bacterial infections in CF airways 23
Show member pathways
 11.87 TNF IL6
12
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
11.86 TNF IL6
13
Yersinia infection 36
11.78 TNF IL6
14
Adipogenesis 1
11.76 TNF IL6
15
Spinal Cord Injury 1
11.72 TNF IL6
16
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.7 TNF IL6
17
Interleukin-4 and 13 signaling 65
11.68 TNF IL6
18
TNF signaling pathway 36
11.67 TNF IL6
19
Insulin resistance 36
Show member pathways
 11.66 TNF IL6
20
Amoebiasis 36
11.62 TNF IL6
21
AGE-RAGE signaling pathway in diabetic complications 36
11.61 TNF IL6
22
Hematopoietic cell lineage 36
11.59 TNF IL6
23
Rheumatoid arthritis 36
11.56 TNF IL6
24
Th1 Differentiation Pathway 64
Show member pathways
 11.46 TNF IL6
25
Pertussis 36
11.46 TNF IL6
26
Dendritic Cells Developmental Lineage Pathway 64
11.44 TNF IL6
27
IgA-Producing B Cells in the Intestine 64
11.38 TNF IL6
28
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.35 TNF IL6
29
Lung fibrosis 1
11.34 TNF IL6
30
Legionellosis 36
11.28 TNF IL6
31
Photodynamic therapy-induced AP-1 survival signaling. 1
11.22 TNF IL6
32
Malaria 36
11.19 TNF IL6
33
Interleukin-10 signaling 65
11.17 TNF IL6
34
amb2 Integrin signaling 1
11.14 TNF IL6
35
Transcription_Role of VDR in regulation of genes involved in osteoporosis 23
11.09 TNF IL6
36
African trypanosomiasis 36
10.97 TNF IL6
37
IL-10 Pathway 63
10.91 TNF IL6
38
Development and heterogeneity of the ILC family 1
10.83 TNF IL6
39
Antifolate resistance 36
10.75 TNF IL6
40
Cytokines and Inflammatory Response 1
10.62 TNF IL6
41
Transcription factor regulation in adipogenesis 1
10.3 TNF IL6
42
Overview of nanoparticle effects 1
9.9 TNF IL6
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GO Terms for External Pathological Resorption

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Biological processes related to External Pathological Resorption according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 cellular response to lipopolysaccharide GO:0071222 9.61 TNF IL6
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.61 TNF IL6
3 positive regulation of DNA-binding transcription factor activity GO:0051091 9.6 TNF IL6
4 defense response to Gram-positive bacterium GO:0050830 9.59 TNF IL6
5 positive regulation of interleukin-6 production GO:0032755 9.58 TNF IL6
6 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.58 TNF IL6
7 regulation of insulin secretion GO:0050796 9.57 TNF IL6
8 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.56 TNF IL6
9 response to glucocorticoid GO:0051384 9.55 TNF IL6
10 positive regulation of smooth muscle cell proliferation GO:0048661 9.54 TNF IL6
11 positive regulation of interleukin-8 production GO:0032757 9.52 TNF IL6
12 humoral immune response GO:0006959 9.51 TNF IL6
13 positive regulation of interleukin-1 beta production GO:0032731 9.49 TNF IL6
14 negative regulation of fat cell differentiation GO:0045599 9.48 TNF IL6
15 positive regulation of chemokine production GO:0032722 9.46 TNF IL6
16 positive regulation of JAK-STAT cascade GO:0046427 9.43 TNF IL6
17 negative regulation of neurogenesis GO:0050768 9.4 TNF IL6
18 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.37 TNF IL6
19 positive regulation of glial cell proliferation GO:0060252 9.32 TNF IL6
20 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.26 TNF IL6
21 positive regulation of neuroinflammatory response GO:0150078 9.16 TNF IL6
22 negative regulation of lipid storage GO:0010888 8.96 TNF IL6
23 vascular endothelial growth factor production GO:0010573 8.62 TNF IL6
Sources

Sources for External Pathological Resorption

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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