MCID: EXT007
MIFTS: 29

Extracutaneous Mastocytoma

Categories: Blood diseases, Rare diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Extracutaneous Mastocytoma

MalaCards integrated aliases for Extracutaneous Mastocytoma:

Name: Extracutaneous Mastocytoma 12 59 15 73
Mastocytoma 44 73
Mast Cell Neoplasm 73
Benign Mastocytoma 73

Characteristics:

Orphanet epidemiological data:

59
extracutaneous mastocytoma
Age of onset: All ages;

Classifications:



External Ids:

Disease Ontology 12 DOID:4659
MeSH 44 D034801
NCIt 50 C7136
SNOMED-CT 68 63175003
Orphanet 59 ORPHA66662
UMLS via Orphanet 74 C0272202
ICD10 via Orphanet 34 C96.2

Summaries for Extracutaneous Mastocytoma

MalaCards based summary : Extracutaneous Mastocytoma, also known as mastocytoma, is related to cutaneous solitary mastocytoma and cutaneous mastocytosis. An important gene associated with Extracutaneous Mastocytoma is KIT (KIT Proto-Oncogene Receptor Tyrosine Kinase), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and NF-kappaB Signaling. Affiliated tissues include skin, bone and bone marrow.

Wikipedia : 76 Extracutaneous mastocytoma presents with benign appearing mast cells occurring in sites other than the... more...

Related Diseases for Extracutaneous Mastocytoma

Diseases related to Extracutaneous Mastocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 cutaneous solitary mastocytoma 33.7 CD2 KIT
2 cutaneous mastocytosis 33.3 CD2 KIT
3 cutaneous mastocytoma 12.5
4 benign mastocytoma 12.0
5 mast-cell sarcoma 11.2
6 gallbladder leiomyoma 10.4 CD34 KIT
7 lung leiomyosarcoma 10.4 CD34 KIT
8 liver leiomyoma 10.4 CD34 KIT
9 deep leiomyoma 10.4 CD34 KIT
10 mediastinal cancer 10.4 CD33 KIT
11 small intestine leiomyosarcoma 10.4 CD34 KIT
12 small intestinal sarcoma 10.4 CD34 KIT
13 gallbladder sarcoma 10.4 CD34 KIT
14 prostate leiomyosarcoma 10.4 CD34 KIT
15 sm-ahnmd 10.4 CD2 KIT
16 indolent systemic mastocytosis 10.4 CD2 KIT
17 gastric leiomyosarcoma 10.4 CD34 KIT
18 breast angiosarcoma 10.4 CD34 KIT
19 plexiform schwannoma 10.4 CD34 KIT
20 senile angioma 10.3 CD34 KIT
21 angiomyoma 10.3 CD34 KIT
22 spindle cell liposarcoma 10.3 CD34 KIT
23 mesenchymal cell neoplasm 10.3 CD34 KIT
24 spindle cell synovial sarcoma 10.2 CD34 KIT
25 endometrial small cell carcinoma 10.2 KIT PTPRC
26 testicular infarct 10.2 KIT PTPRC
27 muscle cancer 10.2 CD34 KIT
28 systemic mastocytosis 10.2 CD2 KIT
29 mast cell disease 10.2 CD2 KIT
30 organ system benign neoplasm 10.2 CD34 KIT
31 leukocyte disease 10.2 CD34 KIT
32 myeloid sarcoma 10.1 KIT PTPRC
33 liver inflammatory pseudotumor 10.1 CD34 PTPRC
34 extraosseous osteosarcoma 10.1 CD34 PTPRC
35 vulvar sarcoma 10.1 CD34 PTPRC
36 chronic monocytic leukemia 10.1 CD34 PTPRC
37 dermatofibrosarcoma protuberans 10.1 CD34 KIT
38 axillary lipoma 10.1 CD68 KIT
39 fox-fordyce disease 10.1 CD68 KIT
40 reticulum cell sarcoma 10.1 CD2 PTPRC
41 small cell carcinoma 10.0 KIT PTPRC
42 follicular mucinosis 10.0 CD2 PTPRC
43 histiocytoma 10.0 KIT PTPRC
44 retina lymphoma 9.9 CD34 CD68
45 sternum cancer 9.9 CD34 CD68
46 cell type cancer 9.9 CD34 KIT
47 melanotic neurilemmoma 9.9 CD34 CD68
48 adult xanthogranuloma 9.9 CD34 CD68
49 diffuse meningeal melanocytosis 9.9 CD34 CD68
50 hemangioma of liver 9.9 CD34 CD68

Graphical network of the top 20 diseases related to Extracutaneous Mastocytoma:



Diseases related to Extracutaneous Mastocytoma

Symptoms & Phenotypes for Extracutaneous Mastocytoma

Drugs & Therapeutics for Extracutaneous Mastocytoma

Search Clinical Trials , NIH Clinical Center for Extracutaneous Mastocytoma

Cochrane evidence based reviews: mastocytoma

Genetic Tests for Extracutaneous Mastocytoma

Anatomical Context for Extracutaneous Mastocytoma

MalaCards organs/tissues related to Extracutaneous Mastocytoma:

41
Skin, Bone, Bone Marrow

Publications for Extracutaneous Mastocytoma

Articles related to Extracutaneous Mastocytoma:

# Title Authors Year
1
Extracutaneous mastocytoma. ( 16751029 )
2006

Variations for Extracutaneous Mastocytoma

Expression for Extracutaneous Mastocytoma

Search GEO for disease gene expression data for Extracutaneous Mastocytoma.

Pathways for Extracutaneous Mastocytoma

GO Terms for Extracutaneous Mastocytoma

Cellular components related to Extracutaneous Mastocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.85 CD2 CD33 CD34 CD68 KIT PTPRC
2 plasma membrane GO:0005886 9.8 CD2 CD33 CD34 CD68 KIT PTPRC
3 cell surface GO:0009986 9.46 CD2 CD34 KIT PTPRC
4 integral component of plasma membrane GO:0005887 9.35 CD2 CD33 CD34 KIT PTPRC
5 cytoplasmic side of plasma membrane GO:0009898 9.26 CD2 KIT
6 external side of plasma membrane GO:0009897 9.02 CD2 CD33 CD34 KIT PTPRC

Biological processes related to Extracutaneous Mastocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.43 CD2 CD33 CD34
2 neutrophil degranulation GO:0043312 9.33 CD33 CD68 PTPRC
3 hemopoiesis GO:0030097 8.96 CD34 KIT
4 T cell differentiation GO:0030217 8.62 KIT PTPRC

Sources for Extracutaneous Mastocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....