MCID: EXT053
MIFTS: 18

Extragonadal Nonseminomatous Germ Cell Tumor

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Extragonadal Nonseminomatous Germ Cell Tumor

MalaCards integrated aliases for Extragonadal Nonseminomatous Germ Cell Tumor:

Name: Extragonadal Nonseminomatous Germ Cell Tumor 12 15
Malignant Extragonadal Non-Seminomatous Germ Cell Tumor 70
Primary Malignant Extragonadal Nonseminoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5677
NCIt 50 C8885
UMLS 70 C1334582

Summaries for Extragonadal Nonseminomatous Germ Cell Tumor

Disease Ontology : 12 An extragonadal germ cell cancer that are located in the pineal gland in the brain, located in the mediastinum or located in the abdomen.

MalaCards based summary : Extragonadal Nonseminomatous Germ Cell Tumor, also known as malignant extragonadal non-seminomatous germ cell tumor, is related to germ cells tumors and nonseminomatous germ cell tumor. An important gene associated with Extragonadal Nonseminomatous Germ Cell Tumor is AFP (Alpha Fetoprotein), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include pineal gland in the brain, mediastinum and abdomen.

Related Diseases for Extragonadal Nonseminomatous Germ Cell Tumor

Diseases related to Extragonadal Nonseminomatous Germ Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 germ cells tumors 10.3
2 nonseminomatous germ cell tumor 10.3
3 extragonadal seminoma 9.9 NUTM1 AFP
4 mediastinal cancer 9.9 NUTM1 AFP
5 liver benign neoplasm 9.9 G6PC1 AFP
6 hepatocellular adenoma 9.8 G6PC1 AFP
7 placenta disease 9.7 MIR512-1 AFP
8 glycogen storage disease 9.7 G6PC1 AFP

Graphical network of the top 20 diseases related to Extragonadal Nonseminomatous Germ Cell Tumor:



Diseases related to Extragonadal Nonseminomatous Germ Cell Tumor

Symptoms & Phenotypes for Extragonadal Nonseminomatous Germ Cell Tumor

Drugs & Therapeutics for Extragonadal Nonseminomatous Germ Cell Tumor

Search Clinical Trials , NIH Clinical Center for Extragonadal Nonseminomatous Germ Cell Tumor

Genetic Tests for Extragonadal Nonseminomatous Germ Cell Tumor

Anatomical Context for Extragonadal Nonseminomatous Germ Cell Tumor

The Foundational Model of Anatomy Ontology organs/tissues related to Extragonadal Nonseminomatous Germ Cell Tumor:

19
Pineal Gland In The Brain, Mediastinum, Abdomen

MalaCards organs/tissues related to Extragonadal Nonseminomatous Germ Cell Tumor:

40
Pineal, Bone Marrow, Liver, Placenta

Publications for Extragonadal Nonseminomatous Germ Cell Tumor

Articles related to Extragonadal Nonseminomatous Germ Cell Tumor:

# Title Authors PMID Year
1
NUT midline carcinoma mimicking a germ cell tumor: a case report. 61
27855672 2016
2
[Posthepatic obstructive jaundice caused by primary extragonadal germ-cell tumor in a patient with glucose-6-phosphatase dehydrogenase deficiency]. 61
20979002 2010
3
Retroperitoneal extragonadal nonseminomatous germ cell tumor with synchronous orbital metastasis. 61
19197374 2009
4
First-line high-dose chemotherapy for patients with poor prognosis extragonadal germ cell tumors: the experience of the European Bone Marrow Transplantation (EBMT) Solid Tumors Working Party. 61
15516940 2004

Variations for Extragonadal Nonseminomatous Germ Cell Tumor

Expression for Extragonadal Nonseminomatous Germ Cell Tumor

Search GEO for disease gene expression data for Extragonadal Nonseminomatous Germ Cell Tumor.

Pathways for Extragonadal Nonseminomatous Germ Cell Tumor

Pathways related to Extragonadal Nonseminomatous Germ Cell Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.27 G6PC1 AFP

GO Terms for Extragonadal Nonseminomatous Germ Cell Tumor

Sources for Extragonadal Nonseminomatous Germ Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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