Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

MalaCards integrated aliases for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor:

Name: Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor ¹² ¹⁵ ⁷¹

Extraosseous Ewing's Tumor ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Bone diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4985

NCIt ⁴⁹ C7135

UMLS ⁷¹ C0279980

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Summaries for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

MalaCards based summary : Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor, also known as extraosseous ewing's tumor, is related to extraskeletal ewing sarcoma and ewing sarcoma, and has symptoms including fever An important gene associated with Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor is CD99 (CD99 Molecule (Xg Blood Group)), and among its related pathways/superpathways are Neuroscience and B Cell Development Pathways. Affiliated tissues include bone, kidney and lung.

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Related Diseases for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Diseases related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 189)

#	Related Disease	Score	Top Affiliating Genes
1	extraskeletal ewing sarcoma	31.5	SYP PTPRC EWSR1 ENO2 CD99
2	ewing sarcoma	30.6	TNFRSF8 SYP PTPRC EWSR1 ENO2 CD99
3	retroperitoneal neuroblastoma	10.4	ENO2 CD99
4	ectomesenchymoma	10.3	ENO2 CD99
5	myocardium cancer	10.3	SYP CD99
6	extraskeletal mesenchymal chondrosarcoma	10.2	EWSR1 CD99
7	ovarian cystic teratoma	10.2	SYP CD99
8	malignant melanocytic neoplasm of the peripheral nerve sheath	10.2	SYP ENO2
9	ureter small cell carcinoma	10.2	SYP ENO2
10	central nervous system mesenchymal non-meningothelial tumor	10.2	EWSR1 CD99
11	anal neuroendocrine tumor	10.2	SYP ENO2
12	sinonasal undifferentiated carcinoma	10.2	SYP ENO2
13	cerebral neuroblastoma	10.2	SYP ENO2
14	papillary tumor of the pineal region	10.2	SYP ENO2
15	small cell carcinoma of the bladder	10.2	SYP ENO2
16	urinary bladder small cell neuroendocrine carcinoma	10.2	SYP ENO2
17	bile duct mucinous adenocarcinoma	10.2	SYP ENO2
18	nodular prostate	10.2	SYP ENO2
19	appendix carcinoid tumor	10.2	SYP ENO2
20	auditory system cancer	10.2	SYP ENO2
21	cloacogenic carcinoma	10.2	SYP ENO2
22	thymus small cell carcinoma	10.2	SYP ENO2
23	mature teratoma of the ovary	10.2	SYP ENO2
24	cystic teratoma	10.2	SYP ENO2
25	duodenal benign neoplasm	10.2	SYP ENO2
26	ampulla of vater neoplasm	10.2	SYP ENO2
27	cerebellar liponeurocytoma	10.2	SYP ENO2
28	papillary ependymoma	10.2	SYP ENO2
29	middle ear adenoma	10.2	SYP ENO2
30	nodular ganglioneuroblastoma	10.2	SYP ENO2
31	ganglioneuroblastoma	10.2	SYP ENO2
32	optic nerve astrocytoma	10.2	SYP ENO2
33	carotid body cancer	10.2	SYP ENO2
34	gastric small cell carcinoma	10.2	SYP ENO2
35	jejunal neoplasm	10.2	SYP ENO2
36	frontal lobe neoplasm	10.2	SYP ENO2
37	sensory organ benign neoplasm	10.2	SYP ENO2
38	cellular ependymoma	10.2	SYP CD99
39	subependymoma	10.2	SYP ENO2
40	pineocytoma	10.2	SYP ENO2
41	cervical large cell neuroendocrine carcinoma	10.2	SYP ENO2
42	kidney rhabdoid cancer	10.2	EWSR1 ENO2
43	large cell neuroendocrine carcinoma	10.2	SYP ENO2
44	lung oat cell carcinoma	10.2	SYP ENO2
45	pineal parenchymal tumor of intermediate differentiation	10.2	SYP ENO2
46	cutaneous ganglioneuroma	10.2	SYP ENO2
47	cervix small cell carcinoma	10.2	SYP ENO2
48	vaginal endometrial stromal sarcoma	10.2	SYP ENO2
49	gliofibroma	10.2	SYP CD99
50	carcinoid tumors, intestinal	10.2	SYP ENO2

Graphical network of the top 20 diseases related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor:

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Symptoms & Phenotypes for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

UMLS symptoms related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor:

fever

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Drugs & Therapeutics for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Search Clinical Trials , NIH Clinical Center for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

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Genetic Tests for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

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Anatomical Context for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

MalaCards organs/tissues related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor:

⁴⁰

Bone, Kidney, Lung, Pineal, Breast, Ovary, Prostate

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Publications for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Articles related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor:

#	Title	Authors	PMID	Year
1	Extraosseous Ewing's tumor of lateral abdominal wall. ⁶¹	Gupta N...Arora MP	24765376	2011
2	Treatment of children with peripheral primitive neuroectodermal tumor or extraosseous Ewing's tumor with Ewing's-directed therapy. ⁶¹	Gururangan S...Meyer WH	9482414	1998
3	Histopathology of childhood sarcomas, Intergroup Rhabdomyosarcoma Studies I and II: clinicopathologic correlation. ⁶¹	Newton WA...Maurer H	3275751	1988

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Genes for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Genes related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CD99	CD99 Molecule (Xg Blood Group)	Protein Coding	5.08	DISEASES inferred ¹⁵
2	ENO2	Enolase 2	Protein Coding	4.79	DISEASES inferred ¹⁵
3	SCN2A	Sodium Voltage-Gated Channel Alpha Subunit 2	Protein Coding	4.76	DISEASES inferred ¹⁵
4	SPARC	Secreted Protein Acidic And Cysteine Rich	Protein Coding	4.56	DISEASES inferred ¹⁵
5	EWSR1	EWS RNA Binding Protein 1	Protein Coding	4.37	DISEASES inferred ¹⁵
6	PTPRC	Protein Tyrosine Phosphatase Receptor Type C	Protein Coding	4.31	DISEASES inferred ¹⁵
7	TNFRSF8	TNF Receptor Superfamily Member 8	Protein Coding	4.07	DISEASES inferred ¹⁵
8	SYP	Synaptophysin	Protein Coding	3.9	DISEASES inferred ¹⁵

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Variations for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

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Expression for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Search GEO for disease gene expression data for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor.

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Pathways for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Pathways related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ⁴	11.67	SYP SCN2A ENO2
2	B Cell Development Pathways ⁶⁴	10.35	TNFRSF8 PTPRC

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GO Terms for Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Cellular components related to Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	plasma membrane	GO:0005886	9.17	TNFRSF8 SPARC SCN2A PTPRC EWSR1 ENO2

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