MCID: EXT003
MIFTS: 22

Extraskeletal Mesenchymal Chondrosarcoma

Categories: Cancer diseases

Aliases & Classifications for Extraskeletal Mesenchymal Chondrosarcoma

MalaCards integrated aliases for Extraskeletal Mesenchymal Chondrosarcoma:

Name: Extraskeletal Mesenchymal Chondrosarcoma 12 15 74
Mesenchymal Extraosseous Chondrosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4548
NCIt 51 C27481
UMLS 74 C1275279

Summaries for Extraskeletal Mesenchymal Chondrosarcoma

MalaCards based summary : Extraskeletal Mesenchymal Chondrosarcoma, also known as mesenchymal extraosseous chondrosarcoma, is related to chondrosarcoma and mesenchymal chondrosarcoma. An important gene associated with Extraskeletal Mesenchymal Chondrosarcoma is SSX1 (SSX Family Member 1), and among its related pathways/superpathways are Glucose / Energy Metabolism and Transcriptional misregulation in cancer. Affiliated tissues include kidney, heart and spleen, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Extraskeletal Mesenchymal Chondrosarcoma

Diseases related to Extraskeletal Mesenchymal Chondrosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 chondrosarcoma 11.0
2 mesenchymal chondrosarcoma 11.0
3 hemihyperplasia, isolated 10.1
4 chromosomal triplication 10.1
5 spindle cell synovial sarcoma 9.9 SSX1 SSX2
6 sarcoma, synovial 9.7 SSX1 SSX2
7 connective tissue cancer 9.7 ENO2 SSX1

Graphical network of the top 20 diseases related to Extraskeletal Mesenchymal Chondrosarcoma:



Diseases related to Extraskeletal Mesenchymal Chondrosarcoma

Symptoms & Phenotypes for Extraskeletal Mesenchymal Chondrosarcoma

GenomeRNAi Phenotypes related to Extraskeletal Mesenchymal Chondrosarcoma according to GeneCards Suite gene sharing:

27 (show all 18)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.8 SSX2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.8 AGO2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.8 AGO2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.8 SSX1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.8 AGO2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.8 AGO2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.8 SSX1 SSX2 AGO2
8 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.8 AGO2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-158 9.8 AGO2
10 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.8 SSX1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.8 SSX2
12 Increased shRNA abundance (Z-score > 2) GR00366-A-45 9.8 AGO2
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.8 SSX1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.8 SSX1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.8 AGO2
16 Increased shRNA abundance (Z-score > 2) GR00366-A-76 9.8 SSX2
17 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.8 SSX2
18 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.8 AGO2

Drugs & Therapeutics for Extraskeletal Mesenchymal Chondrosarcoma

Search Clinical Trials , NIH Clinical Center for Extraskeletal Mesenchymal Chondrosarcoma

Genetic Tests for Extraskeletal Mesenchymal Chondrosarcoma

Anatomical Context for Extraskeletal Mesenchymal Chondrosarcoma

MalaCards organs/tissues related to Extraskeletal Mesenchymal Chondrosarcoma:

42
Kidney, Heart, Spleen, Pancreas

Publications for Extraskeletal Mesenchymal Chondrosarcoma

Articles related to Extraskeletal Mesenchymal Chondrosarcoma:

(show top 50) (show all 53)
# Title Authors Year
1
Extraskeletal Mesenchymal Chondrosarcoma. ( 30407856 )
2018
2
Primary extraskeletal mesenchymal chondrosarcoma arising from the iliac vein. ( 29332118 )
2018
3
Extraskeletal mesenchymal chondrosarcoma at unusual location involving spleen and kidney with review of literature. ( 28631650 )
2017
4
What Is Your Diagnosis? Extraskeletal mesenchymal chondrosarcoma. ( 28857701 )
2017
5
Primary Intracranial Extraskeletal Mesenchymal Chondrosarcoma: Clinical Mimicry as Glomus Jugulare. ( 28867901 )
2017
6
Primary extraskeletal mesenchymal chondrosarcoma arising from the iliac vein. ( 28917072 )
2017
7
Intracranial Extraskeletal Mesenchymal Chondrosarcoma. ( 27565470 )
2016
8
Coexistence of Extraskeletal Mesenchymal Chondrosarcoma and Isolated Hemihyperplasia: A Case Report. ( 27703933 )
2016
9
Extraskeletal Mesenchymal Chondrosarcoma of Shoulder: An Extremely Rare Case. ( 28164050 )
2016
10
Extraskeletal mesenchymal chondrosarcoma arising in adductor magnus with metastatic foci. ( 30364375 )
2016
11
Imaging features of extraskeletal mesenchymal chondrosarcoma of the hand. ( 25797212 )
2015
12
A rare case of extraskeletal mesenchymal chondrosarcoma with dedifferentiation arising from the buccal space in a young male. ( 25838713 )
2015
13
Management of renal extraskeletal mesenchymal chondrosarcoma. ( 25511186 )
2014
14
Primary retroperitoneal extraskeletal mesenchymal chondrosarcoma involving the vena cava: A case report. ( 24932271 )
2014
15
Primary extraskeletal mesenchymal chondrosarcoma of the anterior mediastinum. ( 24255641 )
2013
16
Primary extraskeletal mesenchymal chondrosarcoma of the vulva. ( 24328027 )
2013
17
Extraskeletal mesenchymal chondrosarcoma in the axillary region: reports of two cases. ( 23136576 )
2012
18
Radiological features and pathology of extraskeletal mesenchymal chondrosarcoma. ( 22726976 )
2012
19
Extraskeletal mesenchymal chondrosarcoma of the pleura: report of a rare case. ( 21393900 )
2011
20
Intramuscular, extraskeletal mesenchymal chondrosarcoma. ( 23548257 )
2011
21
Cytologic features and differential diagnosis in a case of extraskeletal mesenchymal chondrosarcoma: a case report. ( 20014564 )
2009
22
Primary retroperitoneal extraskeletal mesenchymal chondrosarcoma: a computed tomography diagnosis. ( 17989325 )
2007
23
Primary extraskeletal mesenchymal chondrosarcoma arising from the pancreas. ( 18071285 )
2007
24
Extraskeletal mesenchymal chondrosarcoma of the forearm: a case report. ( 17336849 )
2007
25
Extraskeletal mesenchymal chondrosarcoma of the cervical meninx. ( 17705006 )
2007
26
Extraskeletal mesenchymal chondrosarcoma of the heart responded to systemic chemotherapy: a case report. ( 19746223 )
2007
27
Extraskeletal mesenchymal chondrosarcoma of the kidney. ( 16643625 )
2006
28
Intracranial extraskeletal mesenchymal chondrosarcoma. ( 22266623 )
2006
29
Cutaneous extraskeletal mesenchymal chondrosarcoma in a cat. ( 15842543 )
2005
30
Trisomy 8 as the sole cytogenetic abnormality in a case of extraskeletal mesenchymal chondrosarcoma. ( 15899388 )
2005
31
Extraskeletal mesenchymal chondrosarcoma: an imaging review of ten new patients. ( 16211384 )
2005
32
Imprint cytology of extraskeletal mesenchymal chondrosarcoma of the perineum: a case report. ( 15471258 )
2004
33
Extraskeletal mesenchymal chondrosarcoma. ( 12908575 )
2003
34
Extraskeletal mesenchymal chondrosarcoma: case report. ( 12727057 )
2003
35
Translocation der(13;21)(q10;q10) in skeletal and extraskeletal mesenchymal chondrosarcoma. ( 12011263 )
2002
36
Retroperitoneal extraskeletal mesenchymal chondrosarcoma in a dog. ( 12423033 )
2002
37
Extraskeletal mesenchymal chondrosarcoma involving the heart: report of a case. ( 10929746 )
2000
38
Intracranial extraskeletal mesenchymal chondrosarcoma: case report. ( 10626952 )
2000
39
Extraskeletal mesenchymal chondrosarcoma of the rectus sheath. ( 9297757 )
1997
40
Primary extraskeletal mesenchymal chondrosarcoma in fossa poplitea of a 93-year-old woman. ( 8950579 )
1996
41
Cytogenetic study of extraskeletal mesenchymal chondrosarcoma. A case report. ( 8603349 )
1996
42
Extraskeletal mesenchymal chondrosarcoma of the labium majus. ( 8774664 )
1996
43
Extraskeletal mesenchymal chondrosarcoma of the orbit. ( 8374880 )
1993
44
Extraskeletal mesenchymal chondrosarcoma. ( 8430193 )
1993
45
Primary extraskeletal mesenchymal chondrosarcoma of the lid. ( 2044980 )
1991
46
Extraskeletal mesenchymal chondrosarcoma of the mediastinum. ( 2242853 )
1990
47
Extraskeletal mesenchymal chondrosarcoma in a cow. ( 2794151 )
1989
48
Extraskeletal mesenchymal chondrosarcoma: case report and review of the literature. ( 2409241 )
1985
49
An ultrastructural study of extraskeletal mesenchymal chondrosarcoma. ( 6524380 )
1984
50
Extraskeletal mesenchymal chondrosarcoma of the orbit. ( 7174941 )
1982

Variations for Extraskeletal Mesenchymal Chondrosarcoma

Cosmic variations for Extraskeletal Mesenchymal Chondrosarcoma:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM6939344 INSR bone,extraskeletal,chondrosarcoma,mesenchymal c.1670C>T p.T557M 19:7166345-7166345 0
2 COSM150793 AR bone,extraskeletal,chondrosarcoma,mesenchymal c.2440T>G p.F814V 23:67721954-67721954 0
3 COSM6939346 bone,extraskeletal,chondrosarcoma,mesenchymal c.844T>G p.F282V 23:67721954-67721954 0
4 COSM1245279 bone,extraskeletal,chondrosarcoma,mesenchymal c.1870T>G p.F624V 23:67721954-67721954 0
5 COSM6939345 bone,extraskeletal,chondrosarcoma,mesenchymal c.1670C>T p.T557M 19:7166345-7166345 0

Expression for Extraskeletal Mesenchymal Chondrosarcoma

Search GEO for disease gene expression data for Extraskeletal Mesenchymal Chondrosarcoma.

Pathways for Extraskeletal Mesenchymal Chondrosarcoma

Pathways related to Extraskeletal Mesenchymal Chondrosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.45 CYP1A2 ENO2
2 10.89 SSX1 SSX2

GO Terms for Extraskeletal Mesenchymal Chondrosarcoma

Biological processes related to Extraskeletal Mesenchymal Chondrosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 post-embryonic development GO:0009791 8.62 AGO2 CYP1A2

Molecular functions related to Extraskeletal Mesenchymal Chondrosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleic acid binding GO:0003676 8.8 AGO2 SSX1 SSX2

Sources for Extraskeletal Mesenchymal Chondrosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....