MCID: EXT009
MIFTS: 26

Extratemporal Epilepsy

Categories: Neuronal diseases

Aliases & Classifications for Extratemporal Epilepsy

MalaCards integrated aliases for Extratemporal Epilepsy:

Name: Extratemporal Epilepsy 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:2544
NCIt 51 C7760
UMLS 74 C0270849

Summaries for Extratemporal Epilepsy

Disease Ontology : 12 An epilepsy syndrome that is located in an area of the brain other than the temporal lobe.

MalaCards based summary : Extratemporal Epilepsy is related to epilepsy and hypohidrotic ectodermal dysplasia autosomal recessive. An important gene associated with Extratemporal Epilepsy is EDAR (Ectodysplasin A Receptor), and among its related pathways/superpathways are Thromboxane A2 receptor signaling and Alpha-synuclein signaling. Affiliated tissues include brain, temporal lobe and skin, and related phenotype is growth/size/body region.

Related Diseases for Extratemporal Epilepsy

Graphical network of the top 20 diseases related to Extratemporal Epilepsy:



Diseases related to Extratemporal Epilepsy

Symptoms & Phenotypes for Extratemporal Epilepsy

MGI Mouse Phenotypes related to Extratemporal Epilepsy:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.23 EDAR EXT1 HCK PIR PLP1 TGM2

Drugs & Therapeutics for Extratemporal Epilepsy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Stress Sensitivity and Hyperemotivity in Epilepsy Compared to and a Group of Healthy Volunteers Recruiting NCT03464370 Not Applicable

Search NIH Clinical Center for Extratemporal Epilepsy

Genetic Tests for Extratemporal Epilepsy

Anatomical Context for Extratemporal Epilepsy

MalaCards organs/tissues related to Extratemporal Epilepsy:

42
Brain, Temporal Lobe, Skin

The Foundational Model of Anatomy Ontology organs/tissues related to Extratemporal Epilepsy:

20
An Area Of The Brain Other Than The Temporal Lobe

Publications for Extratemporal Epilepsy

Articles related to Extratemporal Epilepsy:

(show top 50) (show all 58)
# Title Authors Year
1
Role of resting state MRI temporal latency in refractory pediatric extratemporal epilepsy lateralization. ( 30350326 )
2019
2
Surgical Treatment of Extratemporal Epilepsy: Results and Prognostic Factors. ( 29618099 )
2019
3
Multimodal Imaging in Extratemporal Epilepsy Surgery. ( 29796351 )
2018
4
The oxymoron of image-guided resection in 3 T MRI-negative extratemporal epilepsy: Technique and postoperative results. ( 29358107 )
2018
5
Resection planning in extratemporal epilepsy surgery using 3D multimodality imaging and intraoperative MRI. ( 27931117 )
2017
6
PET imaging in extratemporal epilepsy requires consideration of electroclinical findings. ( 27399879 )
2016
7
Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy. ( 24378203 )
2014
8
Identifying the cortical substrates of interictal epileptiform activity in patients with extratemporal epilepsy: An EEG-fMRI sequential analysis and FDG-PET study. ( 23362864 )
2013
9
Antiepileptic medications after extratemporal epilepsy surgery: when do we stop? ( 23447729 )
2013
10
SISCOM and FDG-PET in patients with non-lesional extratemporal epilepsy: correlation with intracranial EEG, histology, and seizure outcome. ( 23531745 )
2013
11
Integration of functional neuronavigation and intraoperative MRI in surgery for drug-resistant extratemporal epilepsy close to eloquent brain areas. ( 23544410 )
2013
12
Surgical outcomes in patients with extratemporal epilepsy and subtle or normal magnetic resonance imaging findings. ( 23615090 )
2013
13
Comparing the effects of cortical resection and vagus nerve stimulation in patients with nonlesional extratemporal epilepsy. ( 23892577 )
2013
14
Ictal PET in presurgical workup of refractory extratemporal epilepsy. ( 24339606 )
2013
15
Long-term seizure outcome and risk factors for recurrence after extratemporal epilepsy surgery. ( 22417071 )
2012
16
Scalp and intracranial EEG in medically intractable extratemporal epilepsy with normal MRI. ( 22792484 )
2012
17
Seizure outcome after extratemporal epilepsy surgery in childhood. ( 22816374 )
2012
18
Excellent outcomes after extratemporal epilepsy surgery in children. ( 22861682 )
2012
19
Individually tailored extratemporal epilepsy surgery in children: anatomo-electro-clinical features and outcome predictors in a population of 53 cases. ( 22902651 )
2012
20
Surgical management of medial extratemporal epilepsy. ( 22939075 )
2012
21
Social outcomes after temporal or extratemporal epilepsy surgery: a systematic review. ( 21561446 )
2011
22
Cognitive outcome after extratemporal epilepsy surgery in childhood. ( 22032791 )
2011
23
An outcome analysis of seventeen patients treated surgically for intractable extratemporal epilepsy. ( 20845601 )
2010
24
Intracranial electroencephalography seizure onset patterns and surgical outcomes in nonlesional extratemporal epilepsy. ( 19072306 )
2009
25
The impact of extratemporal epilepsy surgery on quality of life. ( 19250976 )
2009
26
Predictors of quality of life after resective extratemporal epilepsy surgery in adults in long-term follow-up. ( 19428270 )
2009
27
Quality of life after extratemporal epilepsy surgery: a prospective clinical study. ( 17919811 )
2008
28
Long-term outcome of extratemporal epilepsy surgery among 154 adult patients. ( 18377245 )
2008
29
Pediatric extratemporal epilepsy presenting with a complex auditory aura. ( 18539574 )
2008
30
Multistage epilepsy surgery: safety, efficacy, and utility of a novel approach in pediatric extratemporal epilepsy. ( 18596454 )
2008
31
Psychosocial outcome after extratemporal epilepsy surgery: a prospective clinical study. ( 18597225 )
2008
32
Outcome of extratemporal epilepsy surgery experience of a single center. ( 18812963 )
2008
33
(1)H MR spectroscopic imaging in patients with MRI-negative extratemporal epilepsy: correlation with ictal onset zone and histopathology. ( 17340102 )
2007
34
Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery. ( 17486287 )
2007
35
Pre-surgical evaluation and surgical treatment in children with extratemporal epilepsy. ( 16832668 )
2006
36
Multistage epilepsy surgery: safety, efficacy, and utility of a novel approach in pediatric extratemporal epilepsy. ( 15670380 )
2005
37
Surgical Treatment for Extratemporal Epilepsy. ( 15043808 )
2004
38
Comparison of magnetoencephalographic spikes with and without concurrent electroencephalographic spikes in extratemporal epilepsy. ( 15240925 )
2004
39
Ictal SPECT in nonlesional extratemporal epilepsy. ( 15281955 )
2004
40
Successful selection of patients with intractable extratemporal epilepsy using non-invasive investigations. ( 14630496 )
2003
41
Magnetoencephalographically directed review of high-spatial-resolution surface-coil MR images improves lesion detection in patients with extratemporal epilepsy. ( 12461274 )
2002
42
Ictal ECD-SPECT differentiates between temporal and extratemporal epilepsy: confirmation by excellent postoperative seizure control. ( 11258411 )
2001
43
Curved reconstructions versus three-dimensional surface rendering in the demonstration of cortical lesions in patients with extratemporal epilepsy. ( 11283420 )
2001
44
The absence of interictal spikes with documented seizures suggests extratemporal epilepsy. ( 11422335 )
2001
45
Results of surgery in patients with refractory extratemporal epilepsy with normal or nonlocalizing magnetic resonance findings investigated with subdural grids. ( 11488889 )
2001
46
Magnetoencephalography in extratemporal epilepsy. ( 10831110 )
2000
47
Interictal, unifocal spikes in refractory extratemporal epilepsy predict ictal origin and postsurgical outcome. ( 11018495 )
2000
48
Subtraction peri-ictal SPECT is predictive of extratemporal epilepsy surgery outcome. ( 11113221 )
2000
49
Extratemporal epilepsy in children: candidate selection and surgical treatment. ( 11156299 )
2000
50
Focal extratemporal epilepsy: clinical features, EEG patterns, and surgical approach. ( 10465493 )
1999

Variations for Extratemporal Epilepsy

Expression for Extratemporal Epilepsy

Search GEO for disease gene expression data for Extratemporal Epilepsy.

Pathways for Extratemporal Epilepsy

Pathways related to Extratemporal Epilepsy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.61 HCK TGM2
2 10.13 HCK TOR1A

GO Terms for Extratemporal Epilepsy

Biological processes related to Extratemporal Epilepsy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glycosaminoglycan biosynthetic process GO:0006024 9.32 EXT1 HAS1
2 hair follicle development GO:0001942 9.26 EDAR WNT10A
3 mesoderm development GO:0007498 9.16 EXT1 HCK
4 central nervous system myelination GO:0022010 8.96 MYRF PLP1
5 salivary gland cavitation GO:0060662 8.62 EDAR TGM2

Sources for Extratemporal Epilepsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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