EVN
MCID: EXT044
MIFTS: 25

Extraventricular Neurocytoma (EVN)

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Extraventricular Neurocytoma

MalaCards integrated aliases for Extraventricular Neurocytoma:

Name: Extraventricular Neurocytoma 59 73
Evn 59

Classifications:

Orphanet: 59  
Rare neurological diseases


External Ids:

Orphanet 59 ORPHA251927
UMLS 73 C2985175

Summaries for Extraventricular Neurocytoma

MalaCards based summary : Extraventricular Neurocytoma, also known as evn, is related to central neurocytoma and oligodendroglioma. An important gene associated with Extraventricular Neurocytoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Vincristine and Carboplatin have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, temporal lobe and bone.

Related Diseases for Extraventricular Neurocytoma

Diseases related to Extraventricular Neurocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 central neurocytoma 30.7 GFAP SYP
2 oligodendroglioma 30.3 GFAP IDH1 SYP
3 ganglioglioma 30.3 GFAP SYP
4 neurofibromatosis, type i 10.2
5 temporal lobe epilepsy 10.2
6 epilepsy 10.2
7 anaplastic ganglioglioma 10.2
8 desmoplastic infantile ganglioglioma 10.0 GFAP SYP
9 lung combined type small cell carcinoma 10.0 GFAP SYP
10 cellular ependymoma 10.0 GFAP SYP
11 ependymoma 10.0 GFAP SYP
12 chordoid meningioma 10.0 GFAP SYP
13 central nervous system primitive neuroectodermal neoplasm 10.0 GFAP SYP
14 clear cell ependymoma 10.0 GFAP SYP
15 chiari malformation 10.0 GFAP SYP
16 cerebral neuroblastoma 10.0 GFAP SYP
17 subependymal glioma 10.0 GFAP SYP
18 astroblastoma 10.0 GFAP SYP
19 cerebral ventricle cancer 10.0 GFAP SYP
20 pineal gland cancer 10.0 GFAP SYP
21 melanotic neuroectodermal tumor 10.0 GFAP SYP
22 benign ependymoma 10.0 GFAP SYP
23 obstructive hydrocephalus 10.0 GFAP SYP
24 hydrocephalus 10.0 GFAP SYP
25 medulloepithelioma 10.0 GFAP SYP
26 pineocytoma 10.0 GFAP SYP
27 subependymoma 10.0 GFAP SYP
28 anaplastic ependymoma 10.0 GFAP SYP
29 benign glioma 10.0 GFAP SYP
30 tanycytic ependymoma 10.0 GFAP SYP
31 papillary ependymoma 10.0 GFAP SYP
32 pineoblastoma 10.0 GFAP SYP
33 papilloma of choroid plexus 10.0 GFAP SYP
34 binswanger's disease 10.0 GFAP SYP
35 cystic teratoma 10.0 GFAP SYP
36 teratoma 10.0 GFAP SYP
37 subependymal giant cell astrocytoma 10.0 GFAP SYP
38 central nervous system benign neoplasm 10.0 GFAP SYP
39 nervous system benign neoplasm 10.0 GFAP SYP
40 cerebellar liponeurocytoma 10.0 GFAP SYP
41 pilomyxoid astrocytoma 10.0 GFAP SYP
42 medullomyoblastoma 10.0 GFAP SYP
43 ganglioneuroma 10.0 GFAP SYP
44 optic nerve glioma 9.9 GFAP SYP
45 atypical teratoid rhabdoid tumor 9.9 GFAP SYP
46 hemangioblastoma 9.9 GFAP SYP
47 mixed glioma 9.9 GFAP IDH1
48 meningioma, familial 9.9 GFAP SYP
49 glioma susceptibility 1 9.9 GFAP IDH1
50 fibrillary astrocytoma 9.9 GFAP IDH1

Graphical network of the top 20 diseases related to Extraventricular Neurocytoma:



Diseases related to Extraventricular Neurocytoma

Symptoms & Phenotypes for Extraventricular Neurocytoma

Drugs & Therapeutics for Extraventricular Neurocytoma

Drugs for Extraventricular Neurocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vincristine Approved, Investigational Phase 2 57-22-7, 2068-78-2 5978
2
Carboplatin Approved Phase 2 41575-94-4 10339178 38904 498142
3
Dabrafenib Approved, Investigational Phase 2 1195765-45-7 44462760 44516822
4
Trametinib Approved Phase 2 871700-17-3 11707110
5 Antineoplastic Agents, Phytogenic Phase 2
6 Protein Kinase Inhibitors Phase 2
7 Antimitotic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase II Pediatric Study With Dabrafenib in Combination With Trametinib in Patients With HGG and LGG Recruiting NCT02684058 Phase 2 dabrafenib;trametinib;Carboplatin with vincristine

Search NIH Clinical Center for Extraventricular Neurocytoma

Genetic Tests for Extraventricular Neurocytoma

Anatomical Context for Extraventricular Neurocytoma

MalaCards organs/tissues related to Extraventricular Neurocytoma:

41
Spinal Cord, Temporal Lobe, Bone, Lung, Brain, Pineal

Publications for Extraventricular Neurocytoma

Articles related to Extraventricular Neurocytoma:

(show top 50) (show all 59)
# Title Authors Year
1
FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma. ( 29978331 )
2018
2
Extraventricular neurocytoma in the left frontal lobe: A case report and literature review. ( 29378347 )
2018
3
Patterns of care and survival outcomes in patients with an extraventricular neurocytoma: An individual patient data analysis of 201 cases. ( 29547155 )
2018
4
Complete resection of hypervascularised extraventricular neurocytoma after preoperative embolisation. ( 29680750 )
2018
5
Imaging characteristics of cerebral extraventricular neurocytoma with pathological correlation. ( 30062611 )
2018
6
Extraventricular neurocytoma: An uncommon tumor in a young boy. A review of literature. ( 28084281 )
2017
7
Hypothalamic Extraventricular Neurocytoma (EVN) in a Pediatric Patient: A Case of EVN Treated with Subtotal Removal Followed by Adjuvant Radiotherapy. ( 27195261 )
2016
8
Densly calcified cystic extraventricular neurocytoma: Radiological-pathological correlation. ( 27841226 )
2016
9
A clinicopathologic study of extraventricular neurocytoma. ( 27864704 )
2016
10
Progression of Atypical Extraventricular Neurocytoma to Anaplastic Ganglioglioma. ( 27597523 )
2016
11
Central Versus Extraventricular Neurocytoma in Children: A Clinicopathologic Comparison and Review of the Literature. ( 27438020 )
2016
12
Extraventricular neurocytoma of the sellar region: case report and literature review. ( 27398267 )
2016
13
Extraventricular neurocytoma in the left temporal lobe: A case report and review of the literature. ( 27313678 )
2016
14
Extraventricular neurocytoma mimicking bone tumor in thoracic spinal column. ( 26235460 )
2015
15
Atypical extraventricular neurocytoma in a 3-year-old girl: case report with radiological-pathological correlation. ( 25894757 )
2015
16
Extraventricular neurocytoma treated with 177Lu DOTATATE PRRT induction and maintenance therapies. ( 25608145 )
2015
17
Mesial temporal extraventricular neurocytoma: a rare cause of refractory complex partial seizure. ( 24691302 )
2014
18
Extraventricular Neurocytoma and Ganglioneurocytoma: Advanced MR Imaging, Histopathological, and Chromosomal Findings. ( 24787229 )
2014
19
Behavioral disorders as unusual presentation of pediatric extraventricular neurocytoma: report on two cases and review of the literature. ( 25524219 )
2014
20
Extraventricular neurocytoma of the sellar region with spinal dissemination. ( 23250388 )
2014
21
Extraventricular neurocytoma in pediatric populations: A case report and review of the literature. ( 24179531 )
2013
22
Extensively calcified cystic extraventricular neurocytoma. ( 24441253 )
2013
23
Extraventricular neurocytoma, a comprehensive review. ( 24357019 )
2013
24
Rapid local recurrence of an extraventricular neurocytoma that had disappeared after gamma knife radiosurgery. ( 23324299 )
2013
25
Visual and auditory hallucinations revealing cerebellar extraventricular neurocytoma: uncommon presentation for uncommon tumor in uncommon location. ( 24199787 )
2013
26
Computed tomography and magnetic resonance features of extraventricular neurocytoma: a study of eight cases. ( 23332437 )
2013
27
MR imaging of cerebral extraventricular neurocytoma: a report of 9 cases. ( 23042917 )
2013
28
5-aminolevulinic Acid fluorescence discriminates the histological grade of extraventricular neurocytoma. ( 24904890 )
2013
29
Response to: Extraventricular neurocytoma of the sellar region. ( 23659217 )
2013
30
A rare case of a pediatric extraventricular neurocytoma: case report and review of the literature. ( 22167266 )
2012
31
Extraventricular neurocytoma. ( 23591250 )
2012
32
Atypical extraventricular neurocytoma: a rare and challenging case diagnosed on intraoperative cytology. ( 21410797 )
2012
33
MR imaging findings of extraventricular neurocytoma: a series of ten patients confirmed by immunohistochemistry of IDH1 gene mutation. ( 22945896 )
2012
34
Extraventricular neurocytoma of the sellar region. ( 22122710 )
2012
35
Pontine extraventricular neurocytoma in a child. ( 23838270 )
2012
36
Dural metastasis of atypical extraventricular neurocytoma with the codeletion of chromosomes 1p/19q. ( 22118007 )
2011
37
Atypical extraventricular neurocytoma. ( 22200023 )
2011
38
Temporo-mesial extraventricular neurocytoma and cortical dysplasia in focal temporal lobe epilepsy. ( 20851605 )
2011
39
Clinicopathological analysis of central and extraventricular neurocytoma: a report of 17 cases. ( 21181365 )
2010
40
Extraventricular neurocytoma of the vermis in a child. ( 20692164 )
2010
41
Extraventricular neurocytoma with atypical features and ganglionic differentiation. ( 20399667 )
2010
42
Comprehensive review of extraventricular neurocytoma with report of two cases, and comparison with central neurocytoma. ( 20423686 )
2010
43
Extraventricular neurocytoma--report of a case. ( 19484697 )
2009
44
Extraventricular neurocytoma in a child: case report and review of the literature. ( 19339288 )
2009
45
Nonenhancing hypovascular extraventricular neurocytoma. ( 19509069 )
2009
46
Extraventricular neurocytoma in a child mimicking oligodendroglioma: a diagnostic pitfall. ( 19886559 )
2009
47
Interphase cytogenetics for 1p19q and t(1;19)(q10;p10) may distinguish prognostically relevant subgroups in extraventricular neurocytoma. ( 18710393 )
2009
48
Imaging findings of extraventricular neurocytoma: report of 3 cases and review of the literature. ( 18842767 )
2009
49
A case of extraventricular neurocytoma of the spinal cord. ( 18194141 )
2008
50
Extraventricular neurocytoma in neurofibromatosis Type 1: case report. ( 18590398 )
2008

Variations for Extraventricular Neurocytoma

Expression for Extraventricular Neurocytoma

Search GEO for disease gene expression data for Extraventricular Neurocytoma.

Pathways for Extraventricular Neurocytoma

Pathways related to Extraventricular Neurocytoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.49 GFAP SYP
2 10.52 GFAP SYP

GO Terms for Extraventricular Neurocytoma

Molecular functions related to Extraventricular Neurocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 GFAP IDH1 SYP

Sources for Extraventricular Neurocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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