MCID: EXT044
MIFTS: 28

Extraventricular Neurocytoma

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Extraventricular Neurocytoma

MalaCards integrated aliases for Extraventricular Neurocytoma:

Name: Extraventricular Neurocytoma 60 74
Evn 60

Classifications:

Orphanet: 60  
Rare neurological diseases


External Ids:

Orphanet 60 ORPHA251927
UMLS 74 C2985175

Summaries for Extraventricular Neurocytoma

MalaCards based summary : Extraventricular Neurocytoma, also known as evn, is related to central neurocytoma and ganglioglioma. An important gene associated with Extraventricular Neurocytoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Carboplatin and Trametinib have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, temporal lobe and brain.

Related Diseases for Extraventricular Neurocytoma

Diseases related to Extraventricular Neurocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 central neurocytoma 31.6 GFAP SYP
2 ganglioglioma 30.4 GFAP SYP
3 oligodendroglioma 30.1 GFAP IDH1 SYP
4 neurofibromatosis, type i 10.2
5 neurofibromatosis, type iv, of riccardi 10.2
6 temporal lobe epilepsy 10.2
7 epilepsy 10.2
8 anaplastic ganglioglioma 10.2
9 desmoplastic infantile ganglioglioma 10.1 GFAP SYP
10 lung combined type small cell carcinoma 10.1 GFAP SYP
11 cellular ependymoma 10.1 GFAP SYP
12 ependymoma 10.1 GFAP SYP
13 chordoid meningioma 10.1 GFAP SYP
14 central nervous system primitive neuroectodermal neoplasm 10.1 GFAP SYP
15 clear cell ependymoma 10.0 GFAP SYP
16 chiari malformation 10.0 GFAP SYP
17 cerebral neuroblastoma 10.0 GFAP SYP
18 subependymal glioma 10.0 GFAP SYP
19 astroblastoma 10.0 GFAP SYP
20 cerebral ventricle cancer 10.0 GFAP SYP
21 pineal gland cancer 10.0 GFAP SYP
22 melanotic neuroectodermal tumor 10.0 GFAP SYP
23 benign ependymoma 10.0 GFAP SYP
24 obstructive hydrocephalus 10.0 GFAP SYP
25 hydrocephalus 10.0 GFAP SYP
26 medulloepithelioma 10.0 GFAP SYP
27 pineocytoma 10.0 GFAP SYP
28 subependymoma 10.0 GFAP SYP
29 anaplastic ependymoma 10.0 GFAP SYP
30 tanycytic ependymoma 10.0 GFAP SYP
31 papillary ependymoma 10.0 GFAP SYP
32 pineoblastoma 10.0 GFAP SYP
33 papilloma of choroid plexus 10.0 GFAP SYP
34 binswanger's disease 10.0 GFAP SYP
35 cystic teratoma 10.0 GFAP SYP
36 teratoma 10.0 GFAP SYP
37 subependymal giant cell astrocytoma 10.0 GFAP SYP
38 central nervous system benign neoplasm 10.0 GFAP SYP
39 cerebellar liponeurocytoma 10.0 GFAP SYP
40 pilomyxoid astrocytoma 10.0 GFAP SYP
41 medullomyoblastoma 10.0 GFAP SYP
42 ganglioneuroma 9.9 GFAP SYP
43 optic nerve glioma 9.9 GFAP SYP
44 infratentorial cancer 9.9 GFAP SYP
45 atypical teratoid rhabdoid tumor 9.9 GFAP SYP
46 hemangioblastoma 9.9 GFAP SYP
47 mixed glioma 9.9 GFAP IDH1
48 meningioma, familial 9.9 GFAP SYP
49 glioma susceptibility 1 9.9 GFAP IDH1
50 fibrillary astrocytoma 9.8 GFAP IDH1

Graphical network of the top 20 diseases related to Extraventricular Neurocytoma:



Diseases related to Extraventricular Neurocytoma

Symptoms & Phenotypes for Extraventricular Neurocytoma

Drugs & Therapeutics for Extraventricular Neurocytoma

Drugs for Extraventricular Neurocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 2 41575-94-4 10339178 38904 498142
2
Trametinib Approved Phase 2 871700-17-3 11707110
3
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
4
Dabrafenib Approved, Investigational Phase 2 1195765-45-7 44462760 44516822
5 Protein Kinase Inhibitors Phase 2
6 Antineoplastic Agents, Phytogenic Phase 2
7 Antimitotic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase II Pediatric Study With Dabrafenib in Combination With Trametinib in Patients With HGG and LGG Recruiting NCT02684058 Phase 2 dabrafenib;trametinib;Carboplatin with vincristine

Search NIH Clinical Center for Extraventricular Neurocytoma

Genetic Tests for Extraventricular Neurocytoma

Anatomical Context for Extraventricular Neurocytoma

MalaCards organs/tissues related to Extraventricular Neurocytoma:

42
Spinal Cord, Temporal Lobe, Brain, Pineal, Bone, Lung

Publications for Extraventricular Neurocytoma

Articles related to Extraventricular Neurocytoma:

(show top 50) (show all 63)
# Title Authors Year
1
Complete resection of hypervascularised extraventricular neurocytoma after preoperative embolisation. ( 29680750 )
2019
2
Mesial temporal extraventricular neurocytoma (mtEVN): A case report and literature review. ( 30603610 )
2019
3
The epidemiology of central and extraventricular neurocytoma in the United States between 2006 and 2014. ( 30859483 )
2019
4
Extraventricular Neurocytoma in the Left Frontal Lobe: A Case Report and Literature Review. ( 29378347 )
2018
5
Patterns of care and survival outcomes in patients with an extraventricular neurocytoma: An individual patient data analysis of 201 cases. ( 29547155 )
2018
6
FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma. ( 29978331 )
2018
7
Imaging characteristics of cerebral extraventricular neurocytoma with pathological correlation. ( 30062611 )
2018
8
Malignant progression of an extraventricular neurocytoma arising from the VIIIth cranial nerve: A case report and literature review. ( 30588667 )
2018
9
Progression of atypical extraventricular neurocytoma to anaplastic ganglioglioma. ( 27597523 )
2017
10
A clinicopathologic study of extraventricular neurocytoma. ( 27864704 )
2017
11
Extraventricular neurocytoma: An uncommon tumor in a young boy. A review of literature. ( 28084281 )
2017
12
Hypothalamic Extraventricular Neurocytoma (EVN) in a Pediatric Patient: A Case of EVN Treated with Subtotal Removal Followed by Adjuvant Radiotherapy. ( 27195261 )
2016
13
Extraventricular neurocytoma in the left temporal lobe: A case report and review of the literature. ( 27313678 )
2016
14
Extraventricular neurocytoma of the sellar region: case report and literature review. ( 27398267 )
2016
15
Central Versus Extraventricular Neurocytoma in Children: A Clinicopathologic Comparison and Review of the Literature. ( 27438020 )
2016
16
Densly calcified cystic extraventricular neurocytoma: Radiological-pathological correlation. ( 27841226 )
2016
17
Extraventricular neurocytoma treated with 177Lu DOTATATE PRRT induction and maintenance therapies. ( 25608145 )
2015
18
Atypical extraventricular neurocytoma in a 3-year-old girl: case report with radiological-pathological correlation. ( 25894757 )
2015
19
Extraventricular neurocytoma mimicking bone tumor in thoracic spinal column. ( 26235460 )
2015
20
Atypical extraventricular neurocytoma:A report of two cases. ( 26881577 )
2015
21
Extraventricular neurocytoma of the sellar region with spinal dissemination. ( 23250388 )
2014
22
Extraventricular neurocytoma, a comprehensive review. ( 24357019 )
2014
23
Mesial temporal extraventricular neurocytoma: a rare cause of refractory complex partial seizure. ( 24691302 )
2014
24
Extraventricular neurocytoma and ganglioneurocytoma: advanced MR imaging, histopathological, and chromosomal findings. ( 24787229 )
2014
25
Behavioral disorders as unusual presentation of pediatric extraventricular neurocytoma: report on two cases and review of the literature. ( 25524219 )
2014
26
MR imaging of cerebral extraventricular neurocytoma: a report of 9 cases. ( 23042917 )
2013
27
Rapid local recurrence of an extraventricular neurocytoma that had disappeared after gamma knife radiosurgery. ( 23324299 )
2013
28
Computed tomography and magnetic resonance features of extraventricular neurocytoma: a study of eight cases. ( 23332437 )
2013
29
Response to: Extraventricular neurocytoma of the sellar region. ( 23659217 )
2013
30
Extraventricular neurocytoma in pediatric populations: A case report and review of the literature. ( 24179531 )
2013
31
Visual and auditory hallucinations revealing cerebellar extraventricular neurocytoma: uncommon presentation for uncommon tumor in uncommon location. ( 24199787 )
2013
32
Extensively calcified cystic extraventricular neurocytoma. ( 24441253 )
2013
33
5-aminolevulinic Acid fluorescence discriminates the histological grade of extraventricular neurocytoma. ( 24904890 )
2013
34
Atypical extraventricular neurocytoma: a rare and challenging case diagnosed on intraoperative cytology. ( 21410797 )
2012
35
Extraventricular neurocytoma of the sellar region. ( 22122710 )
2012
36
A rare case of a pediatric extraventricular neurocytoma: case report and review of the literature. ( 22167266 )
2012
37
MR imaging findings of extraventricular neurocytoma: a series of ten patients confirmed by immunohistochemistry of IDH1 gene mutation. ( 22945896 )
2012
38
Extraventricular neurocytoma. ( 23591250 )
2012
39
Pontine extraventricular neurocytoma in a child. ( 23838270 )
2012
40
Temporo-mesial extraventricular neurocytoma and cortical dysplasia in focal temporal lobe epilepsy. ( 20851605 )
2011
41
Dural metastasis of atypical extraventricular neurocytoma with the codeletion of chromosomes 1p/19q. ( 22118007 )
2011
42
Atypical extraventricular neurocytoma. ( 22200023 )
2011
43
Comprehensive review of extraventricular neurocytoma with report of two cases, and comparison with central neurocytoma. ( 20423686 )
2010
44
Extraventricular neurocytoma with atypical features and ganglionic differentiation. ( 20399667 )
2010
45
Extraventricular neurocytoma of the vermis in a child. ( 20692164 )
2010
46
Clinicopathological analysis of central and extraventricular neurocytoma: a report of 17 cases. ( 21181365 )
2010
47
Interphase cytogenetics for 1p19q and t(1;19)(q10;p10) may distinguish prognostically relevant subgroups in extraventricular neurocytoma. ( 18710393 )
2009
48
Imaging findings of extraventricular neurocytoma: report of 3 cases and review of the literature. ( 18842767 )
2009
49
Extraventricular neurocytoma in a child: case report and review of the literature. ( 19339288 )
2009
50
Extraventricular neurocytoma--report of a case. ( 19484697 )
2009

Variations for Extraventricular Neurocytoma

Expression for Extraventricular Neurocytoma

Search GEO for disease gene expression data for Extraventricular Neurocytoma.

Pathways for Extraventricular Neurocytoma

Pathways related to Extraventricular Neurocytoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.49 GFAP SYP
2 10.52 GFAP SYP

GO Terms for Extraventricular Neurocytoma

Molecular functions related to Extraventricular Neurocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 GFAP IDH1 SYP

Sources for Extraventricular Neurocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....