MCID: EXD002
MIFTS: 24

Exudative Glomerulonephritis

Categories: Nephrological diseases

Aliases & Classifications for Exudative Glomerulonephritis

MalaCards integrated aliases for Exudative Glomerulonephritis:

Name: Exudative Glomerulonephritis 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:4777
NCIt 50 C35706
UMLS 72 C0546345

Summaries for Exudative Glomerulonephritis

MalaCards based summary : Exudative Glomerulonephritis is related to glomerulonephritis and idiopathic neutropenia. An important gene associated with Exudative Glomerulonephritis is CD40LG (CD40 Ligand), and among its related pathways/superpathways are Akt Signaling and Cytokine Signaling in Immune system. Related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Exudative Glomerulonephritis

Diseases related to Exudative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 98)
# Related Disease Score Top Affiliating Genes
1 glomerulonephritis 30.3 IL1B CD40LG
2 idiopathic neutropenia 10.1 IL1B CD40LG
3 lyme disease 10.1 IL1B CD40LG
4 toxoplasmosis 10.0 IL1B CD40LG
5 recurrent corneal erosion 10.0 IL1B CXCL8
6 bagassosis 10.0 IL1B CXCL8
7 peptic esophagitis 10.0 IL1B CXCL8
8 esophagitis 10.0 IL1B CXCL8
9 haemophilus influenzae 10.0 IL1B CXCL8
10 funisitis 9.9 IL1B CXCL8
11 opisthorchiasis 9.9 IL1B CXCL8
12 crohn's colitis 9.9 IL1B CXCL8
13 colitis 9.9 IL1B CXCL8
14 dental pulp disease 9.9 IL1B CXCL8
15 vaginitis 9.9 IL1B CXCL8
16 vaginal disease 9.9 IL1B CXCL8
17 endometrial disease 9.9 IL1B CXCL8
18 pharyngitis 9.9 IL1B CXCL8
19 aseptic meningitis 9.9 IL1B CXCL8
20 meningitis 9.9 IL1B CXCL8
21 pulpitis 9.9 IL1B CXCL8
22 wells syndrome 9.9 IL1B CXCL8
23 middle ear disease 9.9 IL1B CXCL8
24 perinatal necrotizing enterocolitis 9.9 IL1B CXCL8
25 viral encephalitis 9.9 IL1B CXCL8
26 acute respiratory distress syndrome 9.9 IL1B CXCL8
27 prostatitis 9.9 IL1B CXCL8
28 arthritis 9.9 IL1B CXCL8
29 bacterial vaginosis 9.9 IL1B CXCL8
30 newborn respiratory distress syndrome 9.9 IL1B CXCL8
31 demyelinating disease 9.9 IL1B CD40LG
32 gastric ulcer 9.9 IL1B CXCL8
33 peptic ulcer disease 9.9 IL1B CXCL8
34 leptospirosis 9.9 IL1B CXCL8
35 pyelonephritis 9.9 IL1B CXCL8
36 preterm premature rupture of the membranes 9.9 IL1B CXCL8
37 appendicitis 9.9 IL1B CXCL8
38 tonsillitis 9.9 IL1B CXCL8
39 silicosis 9.9 IL1B CXCL8
40 extrinsic allergic alveolitis 9.9 IL1B CXCL8
41 placenta disease 9.9 IL1B CXCL8
42 atrophic gastritis 9.9 IL1B CXCL8
43 gastritis 9.9 IL1B CXCL8
44 allergic contact dermatitis 9.9 IL1B CXCL8
45 contact dermatitis 9.9 IL1B CXCL8
46 pneumoconiosis 9.9 IL1B CXCL8
47 bacterial meningitis 9.9 IL1B CXCL8
48 duodenal ulcer 9.9 IL1B CXCL8
49 aggressive periodontitis 9.9 IL1B CXCL8
50 periodontitis 9.9 IL1B CXCL8

Graphical network of the top 20 diseases related to Exudative Glomerulonephritis:



Diseases related to Exudative Glomerulonephritis

Symptoms & Phenotypes for Exudative Glomerulonephritis

GenomeRNAi Phenotypes related to Exudative Glomerulonephritis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.4 CD40LG CXCL8 IL1B
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.4 CD40LG CXCL8 IL1B

Drugs & Therapeutics for Exudative Glomerulonephritis

Search Clinical Trials , NIH Clinical Center for Exudative Glomerulonephritis

Genetic Tests for Exudative Glomerulonephritis

Anatomical Context for Exudative Glomerulonephritis

Publications for Exudative Glomerulonephritis

Articles related to Exudative Glomerulonephritis:

(show all 27)
# Title Authors PMID Year
1
Acute infection-related glomerulonephritis with disseminated gonococcal infection in a 13-year-old girl. 38
30021740 2018
2
Monoclonal IgG1κ anti-glomerular basement membrane disease: a case report. 38
25446021 2015
3
The many faces of cryoglobulinemic nephropathy: a clinico-pathologic study of 47 cases with emphasis on the value of electron microscopy. 38
25191813 2014
4
C3 glomerulopathy masquerading as acute postinfectious glomerulonephritis. 38
22770945 2012
5
Clinicopathologic Features of IgA-Dominant Postinfectious Glomerulonephritis. 38
23109989 2012
6
Successful treatment of Henoch-Schonlein purpura nephritis with plasma exchange in an adult male. 38
25983918 2008
7
Histologically confirmed superimposition of post-streptococcal acute glomerulonephritis during IgA nephropathy. 38
15619035 2004
8
IgA-dominant acute poststaphylococcal glomerulonephritis complicating diabetic nephropathy. 38
14691907 2003
9
Acute glomerulonephritis associated with acute Q fever: case report and review of the renal complications of Coxiella burnetii infection. 38
9502456 1998
10
Immunohistochemical localization of IL-8 and TGF-beta in streptococcal glomerulonephritis. 38
9048342 1997
11
Spontaneous glomerulonephritis in swine. 38
7779946 1995
12
Glomerular lesions induced in the rabbit by physicochemically altered homologous IgG. 38
1546743 1992
13
Superimposition of poststreptococcal acute glomerulonephritis on the course of IgA nephropathy. 38
2017279 1991
14
Effect of leukocyte stimulation on rabbit immune complex glomerulonephritis. 38
2150083 1990
15
Simultaneous occurrence of acute poststreptococcal glomerulonephritis and acute rheumatic fever. 38
3706418 1986
16
Evolution of membranous nephropathy from a proliferative and exudative glomerulonephritis--a report of three cases studied by serial biopsies. 38
3897088 1985
17
Biopsy proven evolution of post streptococcal glomerulonephritis to rapidly progressive glomerulonephritis of a post infectious type. 38
4006328 1985
18
A case of familial Mediterranean fever with cutaneous vasculitis and immune complex nephritis: light, electron, and immunofluorescent study of renal biopsy. 38
6353905 1983
19
Massive pulmonary hemorrhage and fulminant renal failure associated with immune complex glomerulonephritis. 38
6458092 1981
20
Interstitial nephritis caused by methicillin. Studies in a case complicating staphylococcal sepsis with acute glomerulonephritis. 38
7282631 1981
21
BK papovavirus immune complexes in glomerulonephritis. 38
6264423 1980
22
Incidence of immune complex nephritis following active immunisation with a testosterone-3-BSA conjugate or BSA alone. 38
371322 1979
23
Experimental glomerular lesions induced by chronic immune complex formation. I. Formation and elimination of the immune complex (relationship between the immune status and the glomerular changes). 38
157341 1979
24
Acute post-streptococcal glomerulonephritis in adults: a long-term study. 38
482595 1979
25
Eosinophilic leukocytes in diffuse proliferative and exudative glomerulonephritis. 38
907041 1977
26
Renal biopsy pathology in Auckland, 1969-1976. 38
271872 1977
27
Indentations of the glomerular basement membrane in renal diseases. A light and electron microscopic study on ultrathin serial sections. 38
979163 1976

Variations for Exudative Glomerulonephritis

Expression for Exudative Glomerulonephritis

Search GEO for disease gene expression data for Exudative Glomerulonephritis.

Pathways for Exudative Glomerulonephritis

Pathways related to Exudative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 26)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.95 IL1B CXCL8 CD40LG
2
Show member pathways
12.89 IL1B CXCL8 CD40LG
3
Show member pathways
12.83 IL1B CXCL8 CD40LG
4
Show member pathways
12.35 IL1B CXCL8 CD40LG
5
Show member pathways
11.96 IL1B CXCL8
6
Show member pathways
11.89 IL1B CD40LG
7
Show member pathways
11.86 IL1B CXCL8
8
Show member pathways
11.82 IL1B CXCL8
9 11.8 IL1B CXCL8
10 11.66 IL1B CXCL8
11 11.62 IL1B CXCL8
12 11.58 IL1B CXCL8
13 11.55 IL1B CXCL8
14 11.54 IL1B CXCL8
15 11.49 IL1B CXCL8
16 11.42 IL1B CXCL8
17 11.38 IL1B CXCL8
18
Show member pathways
11.36 CXCL8 CD40LG
19 11.34 IL1B CXCL8 CD40LG
20 11.26 IL1B CXCL8
21 11.15 IL1B CXCL8
22 11.06 IL1B CXCL8
23
Show member pathways
10.93 IL1B CXCL8 CD40LG
24 10.66 IL1B CXCL8 CD40LG
25 10.49 IL1B CXCL8 CD40LG
26 10.4 IL1B CXCL8 CD40LG

GO Terms for Exudative Glomerulonephritis

Biological processes related to Exudative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to lipopolysaccharide GO:0071222 9.43 IL1B CXCL8
2 positive regulation of angiogenesis GO:0045766 9.4 IL1B CXCL8
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.37 IL1B CD40LG
4 immune response GO:0006955 9.33 IL1B CXCL8 CD40LG
5 neutrophil chemotaxis GO:0030593 9.32 IL1B CXCL8
6 positive regulation of T cell proliferation GO:0042102 9.26 IL1B CD40LG
7 inflammatory response GO:0006954 9.13 IL1B CXCL8 CD40LG
8 positive regulation of neutrophil chemotaxis GO:0090023 8.32 CXCL8

Molecular functions related to Exudative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.8 IL1B CXCL8 CD40LG

Sources for Exudative Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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