MCID: EYL002
MIFTS: 27

Eyelid Carcinoma

Categories: Cancer diseases, Eye diseases, Skin diseases

Aliases & Classifications for Eyelid Carcinoma

MalaCards integrated aliases for Eyelid Carcinoma:

Name: Eyelid Carcinoma 12 15
Carcinoma of the Eyelid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6425
NCIt 50 C6078
UMLS 70 C0920196

Summaries for Eyelid Carcinoma

MalaCards based summary : Eyelid Carcinoma, also known as carcinoma of the eyelid, is related to sweat gland cancer and signet ring cell adenocarcinoma. An important gene associated with Eyelid Carcinoma is PIP (Prolactin Induced Protein). The drugs Anesthetics and Radiopharmaceuticals have been mentioned in the context of this disorder. Affiliated tissues include eye, breast and skin.

Related Diseases for Eyelid Carcinoma

Diseases related to Eyelid Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 219)
# Related Disease Score Top Affiliating Genes
1 sweat gland cancer 30.9 PIP KRT7 KRT20
2 signet ring cell adenocarcinoma 30.7 PIP KRT7 KRT20
3 appendix adenocarcinoma 30.6 KRT7 KRT20
4 mucinous adenocarcinoma 30.5 KRT7 KRT20
5 skin benign neoplasm 30.4 PIP KRT7 KRT20
6 lymphoepithelioma-like carcinoma 30.4 KRT7 KRT20
7 apocrine adenocarcinoma 30.3 PIP KRT7
8 eccrine adenocarcinoma 30.3 PIP KRT7
9 papillary adenocarcinoma 30.3 PIP KRT7
10 cribriform carcinoma 30.2 PIP KRT7
11 adenoid squamous cell carcinoma 30.2 KRT7 KRT20
12 benign mesothelioma 30.1 KRT7 KRT20
13 meibomian cyst 30.0 KRT7 KRT20
14 malignant syringoma 30.0 PIP KRT7 KRT20
15 cavernous hemangioma 30.0 KRT7 KRT20
16 rare tumor 10.5
17 adenoid cystic carcinoma 10.3
18 anal canal paget's disease 10.3 PIP KRT7
19 anal paget's disease 10.3 PIP KRT7
20 gastric signet ring cell adenocarcinoma 10.3 PIP KRT7
21 ceruminoma 10.3 PIP KRT7
22 malignant acrospiroma 10.3 PIP KRT7
23 oncocytic breast carcinoma 10.3 PIP KRT7
24 ceruminous adenocarcinoma 10.3 PIP KRT7
25 bartholin's gland disease 10.3 PIP KRT7
26 cutaneous mucoepidermoid carcinoma 10.3 PIP KRT7
27 bartholin's gland carcinoma 10.3 PIP KRT7
28 vulval paget's disease 10.3 PIP KRT7
29 nipples, supernumerary 10.3 PIP KRT20
30 breast mucinous carcinoma 10.3 PIP KRT7
31 lung acinar adenocarcinoma 10.3 PIP KRT20
32 erysipeloid 10.3 PIP KRT7
33 clear cell hidradenoma 10.3 PIP KRT7
34 hidradenoma 10.3 PIP KRT7
35 hidrocystoma 10.3 PIP KRT7
36 eccrine papillary adenocarcinoma 10.3 PIP KRT7
37 eccrine acrospiroma 10.3 PIP KRT7
38 eccrine sweat gland neoplasm 10.3 PIP KRT7
39 dacryocystocele 10.3 PIP KRT7
40 chronic inflammation of lacrimal passage 10.3 PIP KRT7
41 urethral villous adenoma 10.3 KRT7 KRT20
42 villous adenoma 10.3 KRT7 KRT20
43 cutaneous adenocystic carcinoma 10.3 PIP KRT7
44 bladder benign neoplasm 10.3 KRT7 KRT20
45 nephrogenic adenoma of urinary bladder 10.3 KRT7 KRT20
46 tinea cruris 10.3 PIP KRT7
47 atrophic vulva 10.3 KRT7 KRT20
48 pancreatic serous cystadenocarcinoma 10.3 KRT7 KRT20
49 urinary bladder villous adenoma 10.3 KRT7 KRT20
50 vaginal tubulovillous adenoma 10.3 KRT7 KRT20

Graphical network of the top 20 diseases related to Eyelid Carcinoma:



Diseases related to Eyelid Carcinoma

Symptoms & Phenotypes for Eyelid Carcinoma

Drugs & Therapeutics for Eyelid Carcinoma

Drugs for Eyelid Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics Phase 2
2 Radiopharmaceuticals Phase 2
3 Technetium Tc 99m Sulfur Colloid Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Clinical Trial in the Surgical Treatment of Basal Cell Carcinoma of the Eyelid: Surgical Excision With Frozen Section vs. Permanent Section Control Unknown status NCT00663650 Phase 3
2 Sentinel Lymph Node Localization and Biopsy for Sebaceous Gland Carcinoma of the Eyelid Recruiting NCT00832429 Phase 2 Tc99m-Sulfur colloid

Search NIH Clinical Center for Eyelid Carcinoma

Genetic Tests for Eyelid Carcinoma

Anatomical Context for Eyelid Carcinoma

MalaCards organs/tissues related to Eyelid Carcinoma:

40
Eye, Breast, Skin, Lung, Appendix, Lymph Node, Kidney

Publications for Eyelid Carcinoma

Articles related to Eyelid Carcinoma:

(show top 50) (show all 421)
# Title Authors PMID Year
1
Merkel cell carcinoma of the eyelid. 61
33339613 2021
2
Sebaceous carcinoma of the eyelid: 21-year experience in a Nordic country. 61
32749765 2021
3
Differences in 7th and 8th edition American Joint Committee on Cancer staging for periocular sebaceous carcinoma. 61
32822657 2021
4
Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Somatic Mutations in CDH1 and Other Clinically Actionable Mutations Imply Early Use of Targeted Agents. 61
33617508 2021
5
Atypical presentation of an endocrine mucin-producing sweat gland carcinoma of the eyelid. 61
32116079 2021
6
Serum Malondialdehyde as a Biomarker of Oxidative Stress in Patients with Primary Ocular Carcinoma: Impact on Response to Chemotherapy. 61
33664564 2021
7
Bioinformatics analysis of the microRNA-mRNA network in sebaceous gland carcinoma of the eyelid. 61
33179085 2021
8
Sebaceous Carcinoma of the Eyelid: A Systematic Review and Meta-Analysis. 61
33347004 2021
9
Eyelid carcinoma: An experience from a tertiary cancer center. 61
33380651 2020
10
Diagnostic and treatment challenges of a case of primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid. 61
33054772 2020
11
Rare Case of Lymphoepithelioma-like Carcinoma of the Eyelid. 61
33099565 2020
12
Molecular profiling of a primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid. 61
32358805 2020
13
Adenoid Cystic Carcinoma of the Eyelid Can Locally Recur and Mimic Basal Cell Carcinoma: Case Report and Review of the Literature. 61
32118847 2020
14
Clinical features and prognosis of sebaceous carcinoma arising in the eyelid or conjunctiva. 61
32642990 2020
15
Pedunculated poorly differentiated papillary sebaceous carcinoma of the eyelid. 61
31020881 2020
16
Caspase-3, p53 and Bcl-2 expression in basal cell carcinoma of the eyelid. 61
32994776 2020
17
Adenosquamous Carcinoma of the Upper Eyelid in a Dog. 61
32690283 2020
18
Sclerosing Signet Ring Cell Carcinoma of the Lacrimal Gland: A Potentially New Primary Entity. 61
33005616 2020
19
Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid With Locoregional Metastasis to the Parotid Gland. 61
31977506 2020
20
A Metastatic Neuroendocrine Eyelid Carcinoma Originating From the Ampulla of Vater. 61
32049941 2020
21
Whole-exome sequencing for ocular adnexal sebaceous carcinoma suggests PCDH15 as a novel mutation associated with metastasis. 61
31937901 2020
22
Mucinous eccrine carcinoma of the eyelid: A case report study. 61
32874444 2020
23
Nordic treatment practices survey and consensus for treatment of eyelid sebaceous carcinoma. 61
32178641 2020
24
Basal Cell Carcinoma of the Eyelid With Metaplastic Bone Formation. 61
31809487 2020
25
Treatment of Recurrent Primary Cutaneous Mucinous Carcinoma of the Eyelid with Modified Wide Local Excision. 61
33381336 2020
26
Surgical Treatment of Recurrent Lower Eyelid Sebaceous Gland Carcinoma and Reconstruction with Pedicled Nasolabial and Non-vascularised Buccal Mucosal Flaps. 61
31624431 2019
27
Predictive Value of Preoperative Periocular Skin Cancer Measurements for Final Mohs Defect Size. 61
31206459 2019
28
A case series of Merkel cell carcinoma of the eyelid: a rare entity often misdiagnosed. 61
30373432 2019
29
Radiotherapy for localized sebaceous carcinoma of the eyelid: a retrospective analysis of 83 patients. 61
31271440 2019
30
High-dose-rate interstitial brachytherapy for a bulky sebaceous carcinoma of the eyelid: A case report. 61
31624595 2019
31
Exploration of potential key pathways and genes in multiple ocular cancers through bioinformatics analysis. 61
31309275 2019
32
Mould-based surface high-dose-rate brachytherapy for eyelid carcinoma. 61
31749853 2019
33
Merkel cell carcinoma of the eyelid: A review. 61
30871952 2019
34
The practice patterns in the management of sebaceous carcinoma of the eyelid in the Asia Pacific region. 61
30952958 2019
35
Impact of clinicopathologic factors on survival in patients with sebaceous carcinoma of the eyelid - a population-based analysis. 61
30373440 2019
36
Clinicopathological features of considerable reduction in androgen receptor expression in sebaceous gland carcinoma of the eyelid. 61
30027448 2019
37
Prognostic factors for local recurrence, metastasis and survival for sebaceous carcinoma of the eyelid: observations in 100 patients. 61
30131380 2019
38
Impact of Food and Drug Administration Approval of Vismodegib on Prevalence of Orbital Exenteration as a Necessary Surgical Treatment for Locally Advanced Periocular Basal Cell Carcinoma. 61
30365473 2019
39
Ocular preservation with neoadjuvant vismodegib in patients with locally advanced periocular basal cell carcinoma. 61
30021814 2019
40
Regression of Sebaceous Carcinoma of the Eyelid after a Small Incisional Biopsy: Report of Two Cases. 61
31367586 2019
41
Basal cell carcinoma of the eyelid. 61
31088608 2019
42
Upper eyelid Merkel cell carcinoma treated with neoadjuvant chemotherapy and surgical excision. 61
31048649 2019
43
Treatment of squamous cell carcinoma of the eyelid with imiquimod 5% cream. 61
30851791 2019
44
Change in Eyelid Carcinoma T Category With Use of the 8th Versus 7th Edition of the American Joint Committee on Cancer: Cancer Staging Manual. 61
29877957 2019
45
Cancers of the eye. 61
30203109 2018
46
Gene networks in basal cell carcinoma of the eyelid, analyzed using gene expression profiling. 61
30405815 2018
47
The new 8th edition of TNM staging and its implications for skin cancer: a review by the British Association of Dermatologists and the Royal College of Pathologists, U.K. 61
29923189 2018
48
Endocrine mucin-producing sweat gland carcinoma of the eyelid: A clinical and histological conundrum. 61
29941769 2018
49
Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid Associated With Mucinous Adenocarcinoma. 61
28902090 2018
50
Gamma knife radiosurgery for basal cell carcinoma of the eyelid: report of a case. 61
29080088 2018

Variations for Eyelid Carcinoma

Expression for Eyelid Carcinoma

Search GEO for disease gene expression data for Eyelid Carcinoma.

Pathways for Eyelid Carcinoma

GO Terms for Eyelid Carcinoma

Sources for Eyelid Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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