MCID: EYL002
MIFTS: 34

Eyelid Carcinoma

Categories: Cancer diseases, Eye diseases, Neuronal diseases, Skin diseases

Aliases & Classifications for Eyelid Carcinoma

MalaCards integrated aliases for Eyelid Carcinoma:

Name: Eyelid Carcinoma 12 15
Carcinoma of the Eyelid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6425
NCIt 51 C6078
UMLS 74 C0920196

Summaries for Eyelid Carcinoma

MalaCards based summary : Eyelid Carcinoma, also known as carcinoma of the eyelid, is related to sweat gland cancer and papilloma. An important gene associated with Eyelid Carcinoma is FEZF2 (FEZ Family Zinc Finger 2). The drugs Technetium Tc 99m Sulfur Colloid and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include lymph node, lung and breast, and related phenotype is cellular.

Related Diseases for Eyelid Carcinoma

Diseases related to Eyelid Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 sweat gland cancer 30.3 KRT20 KRT7
2 papilloma 29.9 KRT20 KRT7
3 appendix adenocarcinoma 29.7 KRT20 KRT7
4 adenoid squamous cell carcinoma 29.7 KRT20 KRT7
5 mucinous adenocarcinoma 29.7 KRT20 KRT7
6 meibomian cyst 29.7 KRT20 KRT7
7 lymphoepithelioma-like carcinoma 29.7 KRT20 KRT7
8 merkel cell carcinoma 29.4 KRT20 KRT7
9 sebaceous adenocarcinoma 10.6
10 basal cell carcinoma 1 10.6
11 basal cell carcinoma 10.6
12 squamous cell carcinoma 10.4
13 breast metaplastic carcinoma 10.2 FEZF1 FEZF2
14 lymph node tuberculosis 10.2 FEZF1 FEZF2
15 acute laryngitis 10.2 FEZF1 FEZF2
16 uterine inversion 10.2 FEZF1 FEZF2
17 phaeohyphomycosis 10.2 FEZF1 FEZF2
18 neurodermatitis 10.2 FEZF1 FEZF2
19 anus adenocarcinoma 10.1 KRT7 MFGE8
20 hidrocystoma 10.1 KRT7 MFGE8
21 apocrine sweat gland neoplasm 10.1 KRT7 MFGE8
22 adenoid cystic carcinoma 10.1
23 cystic basal cell carcinoma 10.1 KRT20 KRT7
24 seminal vesicle adenocarcinoma 10.1 KRT20 KRT7
25 transverse colon cancer 10.1 KRT20 KRT7
26 malignant syringoma 10.1 KRT20 KRT7
27 glandular cystitis 10.1 KRT20 KRT7
28 papillary transitional carcinoma 10.1 KRT20 KRT7
29 krukenberg carcinoma 10.1 KRT20 KRT7
30 large intestine adenocarcinoma 10.1 KRT20 KRT7
31 linitis plastica 10.1 KRT20 KRT7
32 lung acinar adenocarcinoma 10.1 KRT20 KRT7
33 small cell carcinoma of the bladder 10.1 KRT20 KRT7
34 small cell carcinoma 10.1 KRT20 KRT7
35 intratubular embryonal carcinoma 10.1 KRT20 KRT7
36 vulval paget's disease 10.1 KRT20 KRT7
37 bile duct cystadenocarcinoma 10.1 KRT20 KRT7
38 bile duct adenoma 10.1 KRT20 KRT7
39 jejunal adenocarcinoma 10.1 KRT20 KRT7
40 ovarian mucinous adenocarcinoma 10.1 KRT20 KRT7
41 thymus adenocarcinoma 10.1 KRT20 KRT7
42 appendix disease 10.1 KRT20 KRT7
43 gastric diffuse adenocarcinoma 10.1 KRT20 KRT7
44 bladder lymphoma 10.1 KRT20 KRT7
45 papillary serous adenocarcinoma 10.1 KRT20 KRT7
46 bladder adenocarcinoma 10.1 KRT20 KRT7
47 chronic cystitis 10.1 KRT20 KRT7
48 vulva adenocarcinoma 10.1 KRT20 KRT7
49 medulloepithelioma 10.1 KRT20 KRT7
50 glycogen-rich clear cell breast carcinoma 10.1 KRT20 KRT7

Graphical network of the top 20 diseases related to Eyelid Carcinoma:



Diseases related to Eyelid Carcinoma

Symptoms & Phenotypes for Eyelid Carcinoma

MGI Mouse Phenotypes related to Eyelid Carcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 BAG3 FEZF1 FEZF2 KRT7 MFGE8

Drugs & Therapeutics for Eyelid Carcinoma

Drugs for Eyelid Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Technetium Tc 99m Sulfur Colloid Phase 2
2 Anesthetics Phase 2
3 Radiopharmaceuticals Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Periocular Basal Cell Carcinoma (BCC): Permanent vs. Frozen Section Pathological Control Unknown status NCT00663650 Phase 3
2 Sentinel Lymph Node (SLN) Biopsy for Sebaceous Gland Carcinoma of Eyelid Recruiting NCT00832429 Phase 2 Tc99m-Sulfur colloid
3 Sentinel Lymph Node (SLN) Biopsy for Conjunctival/Eyelid Melanoma Active, not recruiting NCT00386906 Phase 1

Search NIH Clinical Center for Eyelid Carcinoma

Genetic Tests for Eyelid Carcinoma

Anatomical Context for Eyelid Carcinoma

MalaCards organs/tissues related to Eyelid Carcinoma:

42
Lymph Node, Lung, Breast, Appendix, Skin, Colon, Eye

Publications for Eyelid Carcinoma

Articles related to Eyelid Carcinoma:

(show top 50) (show all 263)
# Title Authors Year
1
Basal cell carcinoma of the eyelid. ( 31088608 )
2019
2
Change in Eyelid Carcinoma T Category With Use of the 8th Versus 7th Edition of the American Joint Committee on Cancer: Cancer Staging Manual. ( 29877957 )
2019
3
Merkel Cell Carcinoma of the Eyelid: a Review. ( 30871952 )
2019
4
Treatment of squamous cell carcinoma of the eyelid with imiquimod 5% cream. ( 30851791 )
2019
5
The practice patterns in the management of sebaceous carcinoma of the eyelid in the Asia Pacific region. ( 30952958 )
2019
6
Pedunculated poorly differentiated papillary sebaceous carcinoma of the eyelid. ( 31020881 )
2019
7
Gene networks in basal cell carcinoma of the eyelid, analyzed using gene expression profiling. ( 30405815 )
2018
8
Gamma knife radiosurgery for basal cell carcinoma of the eyelid: report of a case. ( 29080088 )
2018
9
A case series of Merkel cell carcinoma of the eyelid: a rare entity often misdiagnosed. ( 30373432 )
2018
10
Merkel cell carcinoma of the eyelid and orbit. ( 30541295 )
2018
11
Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid Associated With Mucinous Adenocarcinoma. ( 28902090 )
2018
12
Endocrine mucin-producing sweat gland carcinoma of the eyelid: A clinical and histological conundrum. ( 29941769 )
2018
13
Prognostic factors for local recurrence, metastasis and survival for sebaceous carcinoma of the eyelid: observations in 100 patients. ( 30131380 )
2018
14
Impact of clinicopathologic factors on survival in patients with sebaceous carcinoma of the eyelid - a population-based analysis. ( 30373440 )
2018
15
Clinicopathological features of considerable reduction in androgen receptor expression in sebaceous gland carcinoma of the eyelid. ( 30027448 )
2018
16
Infundibulocystic basal cell carcinoma of the eyelid. ( 28660686 )
2017
17
'En face' ex vivo reflectance confocal microscopy to help the surgery of basal cell carcinoma of the eyelid. ( 27990744 )
2017
18
Primary Cribriform Carcinoma of the Eyelid With Neuroendocrine Features: A Case Report. ( 28300861 )
2017
19
Treatment of Metastatic Eyelid Carcinoma. ( 28885435 )
2017
20
Case series: Merkel cell carcinoma of the eyelid. ( 28985829 )
2017
21
Demonstration of a Borst-Jadassohn-Like Phenomenon in Sebaceous Carcinoma of the Eyelid. ( 26020718 )
2017
22
Bilateral Primary Mucinous Carcinoma of the Eyelid. ( 26950474 )
2017
23
Expression of Anti-apoptotic Protein BAG3 in Human Sebaceous Gland Carcinoma of the Eyelid. ( 28373462 )
2017
24
Primary signet-ring cell/histiocytoid carcinoma of the eyelid expressing androgen receptors and treated with bicalutamide. ( 28543368 )
2017
25
Primary Cutaneous Mucinous Carcinoma of the Eyelid. ( 29043010 )
2017
26
Primary mucinous carcinoma of the eyelid treated with Mohs micrographic surgery. ( 29232431 )
2017
27
Giant basal cell carcinoma of the eyelid: a case history. ( 28154636 )
2016
28
Primary cutaneous histoplasmosis mimicking basal cell carcinoma of the eyelid: A case report and review of literature. ( 27166049 )
2016
29
Clinicopathological analysis of recurrent basal cell carcinoma of the eyelid. ( 26985178 )
2016
30
Merkel Cell Carcinoma of the Eyelid. ( 26979008 )
2016
31
Merkel Cell Carcinoma of the Eyelid. ( 27664912 )
2016
32
Merkel cell carcinoma of the eyelid. A series of 5 cases and review of the literature. ( 26723858 )
2016
33
Recurrent Squamous Cell Carcinoma of the Eyelid Presenting as Trigeminal Neuralgia. ( 28097083 )
2016
34
Verrucous Carcinoma of the Eyelid. ( 27478359 )
2016
35
Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid: A Report of a Case With Molecular Analysis. ( 26675355 )
2016
36
Histopathology of endocrine mucin-producing sweat gland carcinoma of the eyelid. ( 27085285 )
2016
37
GATA3 Positivity in Endocrine Mucin-Producing Sweat Gland Carcinoma and Invasive Mucinous Carcinoma of the Eyelid: Report of 2 Cases. ( 27533071 )
2016
38
Recurrent sebaceous carcinoma of the eyelid: Outcome after postoperative reirradiation. ( 25900883 )
2016
39
Sebaceous Carcinoma of the Eyelid. ( 27218789 )
2016
40
Reply to Letter to the Editor regarding recurrent sebaceous carcinoma of the eyelid: Outcome after postoperative reirradiation. ( 27473551 )
2016
41
Letter to the Editor regarding recurrent sebaceous carcinoma of the eyelid: Outcome after postoperative reirradiation. ( 27473673 )
2016
42
Primary Signet-Ring Cell/Histiocytoid Carcinoma of the Eyelid: A "Binocle" Presentation of the "Monocle Tumor". ( 27391452 )
2016
43
Primary Cutaneous Mucinous Carcinoma of the Eyelid. ( 28913279 )
2016
44
Primary cutaneous adenoid cystic carcinoma of the eyelid and literature review. ( 26466235 )
2015
45
Primary Merkel Cell Carcinoma of the Eyelid-- Clinical, Histopathological, Immunohistochemical and Electron Microscopical Features: A Case Report. ( 26259404 )
2015
46
Muir-Torre Syndrome in a Middle-Aged Chinese Patient with Sebaceous Carcinoma of the Eyelid. ( 24117411 )
2015
47
Endocrine mucin-producing sweat gland carcinoma of the eyelid. ( 26373656 )
2015
48
Cutaneous squamous cell carcinoma of the eyelid masquerading as a chalazion. ( 25479697 )
2015
49
Sebaceous gland carcinoma of the eyelid: clinicopathological features and outcome in Asian Indians. ( 25998946 )
2015
50
Primary cutaneous mucinous carcinoma of the eyelid treated with Mohs surgery. ( 27051692 )
2015

Variations for Eyelid Carcinoma

Expression for Eyelid Carcinoma

Search GEO for disease gene expression data for Eyelid Carcinoma.

Pathways for Eyelid Carcinoma

GO Terms for Eyelid Carcinoma

Biological processes related to Eyelid Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.4 KRT20 KRT7
2 positive regulation of neuron differentiation GO:0045666 9.37 FEZF1 FEZF2
3 forebrain development GO:0030900 9.32 FEZF1 FEZF2
4 regulation of neurogenesis GO:0050767 9.26 FEZF1 FEZF2
5 telencephalon development GO:0021537 9.16 FEZF1 FEZF2
6 cell dedifferentiation GO:0043697 8.96 FEZF1 FEZF2
7 forebrain anterior/posterior pattern specification GO:0021797 8.62 FEZF1 FEZF2

Sources for Eyelid Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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