Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Datasets Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: FCL001
MIFTS: 31

Facial Dermatosis

Categories: Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
Sources

Aliases & Classifications for Facial Dermatosis

About this section

MalaCards integrated aliases for Facial Dermatosis:

Name: Facial Dermatosis 12 15 17
Facial Dermatoses 43 71

Classifications:

MalaCards categories:
Anatomical: Skin diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:3134
MeSH 43 D005148
UMLS 71 C0015456
Sources

Summaries for Facial Dermatosis

About this section
MalaCards based summary : Facial Dermatosis, also known as facial dermatoses, is related to retinal dystrophy, iris coloboma, and comedogenic acne syndrome and skin disease, and has symptoms including pruritus and exanthema. An important gene associated with Facial Dermatosis is AARS1 (Alanyl-TRNA Synthetase 1), and among its related pathways/superpathways is TRP channels. The drugs Doxycycline and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include skin and testes, and related phenotypes are behavior/neurological and integument

Sources

Related Diseases for Facial Dermatosis

About this section

Diseases related to Facial Dermatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 retinal dystrophy, iris coloboma, and comedogenic acne syndrome 10.1
2 skin disease 10.1
3 rosacea 10.1
4 folliculitis 10.1
5 neurofibromatosis, type ii 10.0
6 seborrheic dermatitis 10.0
7 contact dermatitis 10.0
8 dowling-degos disease 1 9.8
9 exanthem 9.8
10 telangiectasis 9.8
11 calcinosis 9.8
12 dermatitis 9.8
13 hypertrichosis 9.8
14 lichen nitidus 9.8
15 lupus erythematosus 9.8
16 alopecia 9.8
17 lipogranulomatosis 9.8
18 posttransplant acute limbic encephalitis 9.8
19 dermatitis, atopic 9.8
20 panniculitis 9.8
21 allergic contact dermatitis 9.8
22 secondary syphilis 9.8
23 syphilis 9.8
24 spongiotic dermatitis 9.8
25 familial episodic pain syndrome 9.7 TRPV3 ANK1
26 dentin sensitivity 9.5 TRPV3 TRPV2
27 scapuloperoneal spinal muscular atrophy 9.4 TRPV3 TRPV2
28 brachyolmia 9.2 TRPV3 TRPV2

Graphical network of the top 20 diseases related to Facial Dermatosis:



Diseases related to Facial Dermatosis
Sources

Symptoms & Phenotypes for Facial Dermatosis

About this section

UMLS symptoms related to Facial Dermatosis:


pruritus, exanthema

MGI Mouse Phenotypes related to Facial Dermatosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.35 AARS1 ANK1 CCNE1 KLK5 TRPV3
2 integument MP:0010771 8.92 AARS1 ANK1 CCNE1 TRPV3
Sources

Drugs & Therapeutics for Facial Dermatosis

About this section

Drugs for Facial Dermatosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
2
Lidocaine Approved, Vet_approved 137-58-6 3676
3
Epinephrine Approved, Vet_approved 51-43-4 5816
4
Racepinephrine Approved 329-65-7 838
5 Antiparasitic Agents
6 Antiprotozoal Agents
7 Anti-Bacterial Agents
8 Anti-Infective Agents
9 Antimalarials
10 Anesthetics
11 Epinephryl borate
12 Tea

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prospective, Open Label, Randomized Study Comparing Bipolar Radiofrequency Potentiated by Infrared Light to Doxycycline in Patient With Papulopustular Rosacea Unknown status NCT02204254 Doxycycline
2 Efficacy of a 585 nm Pulsed Dye Laser (PDL) for the Treatment of Dermatosis Papulosa Nigra, and Compare it to Therapy With Curettage and Electrodesiccation. Completed NCT00710203
3 Pilot Study of Effects and Tolerance of Black Tea Compress Treatment in Facial Eczema and Perioral Dermatitis Completed NCT02941432

Search NIH Clinical Center for Facial Dermatosis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Alclometasone
alclometasone dipropionate
amcinonide
Betamethasone
Betamethasone acetate
Betamethasone benzoate
betamethasone dipropionate
betamethasone sodium phosphate
Betamethasone valerate
BETAMETHASONE VALERATE PWDR
Clobetasol
Clobetasol Propionate
clocortolone
clocortolone pivalate
Desonide
Desoximetasone
Diflorasone
diflorasone diacetate
fluocinolone
Fluocinolone Acetonide
Flurandrenolide
Halcinonide
halobetasol
halobetasol propionate
Hydrocortisone
hydrocortisone acetate
HYDROCORTISONE ACETATE PWDR
HYDROCORTISONE ACETONIDE
Hydrocortisone butyrate
hydrocortisone cypionate
hydrocortisone probutate
HYDROCORTISONE PWDR
Hydrocortisone sodium phosphate
Hydrocortisone sodium succinate
hydrocortisone valerate
HYDROCORTISONE,NONSTERILE PWDR
Lactic acid
LACTIC ACID LIQUID
LACTIC ACID,BUFFERED
prednicarbate
Tretinoin
TRETINOIN PWDR
Triamcinolone
Triamcinolone Acetonide
TRIAMCINOLONE ACETONIDE PWDR
triamcinolone diacetate
triamcinolone hexacetonide

Cochrane evidence based reviews: facial dermatoses

Sources

Genetic Tests for Facial Dermatosis

About this section
Sources

Anatomical Context for Facial Dermatosis

About this section

MalaCards organs/tissues related to Facial Dermatosis:

40
Skin, Testes
Sources

Publications for Facial Dermatosis

About this section

Articles related to Facial Dermatosis:

(show top 50) (show all 99)
# Title Authors PMID Year
1
Face Mask-induced Itch: A Self-questionnaire Study of 2,315 Responders During the COVID-19 Pandemic. 61
32449781 2020
2
Personal protective equipment induced facial dermatoses in healthcare workers managing Coronavirus disease 2019. 61
32396675 2020
3
Anxiety, Depression, and Suicidal Ideation amongst Patients with Facial Dermatoses (Acne, Rosacea, Perioral Dermatitis, and Folliculitis) in Lithuania. 61
32252051 2020
4
Study of Clinical Profile of Patients Presenting with Topical Steroid-Induced Facial Dermatosis to a Tertiary Care Hospital. 61
32477980 2020
5
Demodex folliculorum infestations in common facial dermatoses: acne vulgaris, rosacea, seborrheic dermatitis. 61
32113677 2020
6
Vichy mineralizing water with hyaluronic acid is effective and well tolerated as an adjunct to the management of various dermatoses and after esthetic procedures. 61
31793738 2020
7
Analysis of facial redness by comparing VISIA® from Canfield and CSKIN® from Yanyun Technology. 61
32196761 2020
8
Impact of Abuse of Topical Corticosteroids and Counterfeit Cosmetic Products for the Face: Prospective Demographic Study in Basrah City, Iraq. 61
31573892 2020
9
Lichenoid pseudovesicular papular eruption on nose: A papular facial dermatosis probably related to actinic lichen nitidus or micropapular polymorphous light eruption. 61
31293275 2019
10
Erythematotelangiectatic rosacea may be associated with a subclinical stage of demodicosis: a case-control study. 61
30801673 2019
11
The Role of the Skin Barrier in Periorificial Dermatitis. 61
31542061 2019
12
A case series of demodicosis in children. 61
31197860 2019
13
Interventions for rosacea based on the phenotype approach: an updated systematic review including GRADE assessments. 61
30585305 2019
14
Dermoscopy of Inflammatory Dermatoses (Inflammoscopy): An Up-to-Date Overview. 61
31384489 2019
15
The Use of Oral Antibiotics in the Management of Rosacea 61
31251542 2019
16
New indications for topical ivermectin 1% cream: a case series study. 61
30858780 2019
17
[Facial dermatosis in practice]. 61
30869467 2018
18
Topical Application of 5-Fluorouracil Associated with Distant Seborrheic Dermatitis-like Eruption: Case Report and Review of Seborrheic Dermatitis Cutaneous Reactions after Systemic or Topical Treatment with 5-Fluorouracil. 61
30051297 2018
19
Topical Steroid Damaged/Dependent Face (TSDF): A Study from a Tertiary Care Hospital in Eastern India. 61
30210157 2018
20
Management of necrotizing and non-necrotic bacterial erysipelas of the face in tropical areas: a series of four cases and a review of the literature. 61
30270829 2018
21
A Rare Dermatologic Disease in Pregnancy: Rosacea Fulminans- Case Report and Review of the Literature. 61
30159072 2018
22
Recalcitrant psoriasiform dermatosis of the face: Is it related to pityriasis rubra pilaris? 61
29604103 2018
23
Dermoscopy of granuloma faciale: a description of a new finding. 61
30066773 2018
24
Papulopustular rosacea and rosacea-like demodicosis: two phenotypes of the same disease? 61
29478301 2018
25
Black peel in facial dermatoses. 61
28834124 2018
26
Development of Rifampicin-Indocyanine Green-Loaded Perfluorocarbon Nanodroplets for Photo-Chemo-Probiotic Antimicrobial Therapy. 61
30450048 2018
27
Rosacea in black South Africans with skin phototypes V and VI. 61
28639713 2017
28
Otophyma, Rhinophyma and Telangiectatic Rosacea - A Rare Combination in a Female Patient. 61
28785351 2017
29
The effect of skin moisture, pH, and temperature on the density of Demodex folliculorum and Demodex brevis (Acari: Demodicidae) in students and staff of the Erzincan University, Turkey. 61
28369843 2017
30
Lupus Miliaris Disseminatus Faciei: Not Only a Facial Dermatosis. 61
28119995 2017
31
Misuse of Topical Corticosteroids over Face: A Clinical Study. 61
28584755 2017
32
Misuse of topical corticosteroids on facial skin. A study of 200 patients. 61
28539982 2017
33
Association study of Demodex bacteria and facial dermatoses based on DGGE technique. 61
28063008 2017
34
Two Consecutive Standardized Skin Surface Biopsies: An Improved Sampling Method to Evaluate Demodex Density as a Diagnostic Tool for Rosacea and Demodicosis. 61
27573185 2017
35
Rosacea fulminans during pregnancy. 61
29714890 2017
36
Misuse of topical corticosteroids on the face: A cross-sectional study among dermatology outpatients. 61
27559498 2016
37
Intestinal-borne dermatoses significantly improved by oral application of Escherichia coli Nissle 1917. 61
27340358 2016
38
Sensitive skin. 61
26805416 2016
39
Prolonged Exposure Dermatosis: Reporting High Incidence of an Undiagnosed Facial Dermatosis on a Winter Wilderness Expedition. 61
26165579 2015
40
Interventions for rosacea: abridged updated Cochrane systematic review including GRADE assessments. 61
26099423 2015
41
The use of sodium sulfacetamide in dermatology. 61
26367751 2015
42
[Item 109 - UE 4 Facial dermatoses: acne, rosacea, seborrheic dermatitis]. 61
25846469 2015
43
[Rosacea]. 61
26054168 2015
44
Evaluation of suspected cosmetic induced facial dermatoses with the use of Indian standard series and cosmetic series patch test. 61
25954688 2015
45
Psychologic factors in the development of facial dermatoses. 61
25441469 2014
46
Psychologic consequences of facial dermatoses. 61
25441470 2014
47
Facial skin care products and cosmetics. 61
25441474 2014
48
Biopsies of facial dermatoses made simple. 61
24678686 2014
49
Recent advances in the understanding and management of rosacea. 61
25184040 2014
50
Rosacea under the microscope: characteristic histological findings. 61
23451732 2013
Sources

Variations for Facial Dermatosis

About this section
Sources

Expression for Facial Dermatosis

About this section
Search GEO for disease gene expression data for Facial Dermatosis.
Sources

Pathways for Facial Dermatosis

About this section

Pathways related to Facial Dermatosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
TRP channels 65
10.02 TRPV3 TRPV2
Sources

GO Terms for Facial Dermatosis

About this section

Biological processes related to Facial Dermatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion transport GO:0006816 9.37 TRPV3 TRPV2
2 calcium ion transmembrane transport GO:0070588 9.32 TRPV3 TRPV2
3 response to heat GO:0009408 9.26 TRPV3 TRPV2
4 positive regulation of calcium ion import GO:0090280 9.16 TRPV3 TRPV2
5 calcium ion import across plasma membrane GO:0098703 8.96 TRPV3 TRPV2
6 response to temperature stimulus GO:0009266 8.62 TRPV3 TRPV2

Molecular functions related to Facial Dermatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ion channel activity GO:0005216 9.16 TRPV3 TRPV2
2 calcium channel activity GO:0005262 8.96 TRPV3 TRPV2
3 cation channel activity GO:0005261 8.62 TRPV3 TRPV2
Sources

Sources for Facial Dermatosis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....