MCID: FCL003
MIFTS: 29

Facial Hemiatrophy

Categories: Neuronal diseases, Skin diseases

Aliases & Classifications for Facial Hemiatrophy

MalaCards integrated aliases for Facial Hemiatrophy:

Name: Facial Hemiatrophy 12 44 15 70
Parry-Romberg Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1757
MeSH 44 D005150
NCIt 50 C84703
SNOMED-CT 67 29868009
UMLS 70 C0015458

Summaries for Facial Hemiatrophy

MalaCards based summary : Facial Hemiatrophy, also known as parry-romberg syndrome, is related to systemic scleroderma and optic papillitis, and has symptoms including ataxia and oral manifestations. An important gene associated with Facial Hemiatrophy is SNRNP70 (Small Nuclear Ribonucleoprotein U1 Subunit 70). The drug Ginger has been mentioned in the context of this disorder. Affiliated tissues include skin, brain and eye.

Wikipedia : 73 Parry-Romberg syndrome (PRS) is a rare disease characterized by progressive shrinkage and degeneration... more...

Related Diseases for Facial Hemiatrophy

Diseases related to Facial Hemiatrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 185)
# Related Disease Score Top Affiliating Genes
1 systemic scleroderma 30.9 SNRNP70 EXOSC10 CRP
2 optic papillitis 30.6 MRAP CRP
3 telangiectasis 30.5 SNRNP70 EXOSC10
4 iridocyclitis 30.4 MRAP CRP
5 panuveitis 30.3 MRAP CRP
6 facial paralysis 29.9 KIF21A CRP
7 hemifacial atrophy, progressive 11.4
8 heterochromia iridis 11.3
9 vasculitis 10.5
10 localized scleroderma 10.5
11 retinal vasculitis 10.4
12 linear scleroderma 10.4
13 neuroretinitis 10.4
14 aneurysm 10.4
15 intracranial aneurysm 10.3
16 epilepsy 10.3
17 paresthesia 10.3
18 enophthalmos 10.3
19 alopecia 10.3
20 autoimmune disease 10.2
21 external auditory canal, bilateral atresia of, with congenital vertical talus 10.2
22 torticollis 10.2
23 vitiligo-associated multiple autoimmune disease susceptibility 6 10.2
24 corneal dystrophy, band-shaped 10.2
25 branchiootic syndrome 1 10.2
26 vitiligo-associated multiple autoimmune disease susceptibility 1 10.2
27 intraocular pressure quantitative trait locus 10.2
28 mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome 10.2
29 suppression amblyopia 10.2
30 amblyopia 10.2
31 lyme disease 10.2
32 migraine without aura 10.2
33 patent foramen ovale 10.2
34 temporal lobe epilepsy 10.2
35 movement disease 10.2
36 hypotropia 10.2
37 alien hand syndrome 10.2
38 rasmussen johnsen thomsen syndrome 10.2
39 encephalopathy 10.2
40 rasmussen subacute encephalitis 10.2
41 myopathy 10.2
42 diffuse scleroderma 10.2 SNRNP70 EXOSC10
43 syndromic x-linked intellectual disability cabezas type 10.2 SNRNP70 EXOSC10
44 dyskinesia of esophagus 10.2 SNRNP70 EXOSC10
45 crest syndrome 10.2 SNRNP70 EXOSC10
46 dowling-degos disease 1 10.1
47 focal epilepsy 10.1
48 childhood type dermatomyositis 10.1 SNRNP70 EXOSC10
49 multiple sclerosis 10.1
50 dyschromatosis symmetrica hereditaria 10.1

Graphical network of the top 20 diseases related to Facial Hemiatrophy:



Diseases related to Facial Hemiatrophy

Symptoms & Phenotypes for Facial Hemiatrophy

UMLS symptoms related to Facial Hemiatrophy:


ataxia; oral manifestations

Drugs & Therapeutics for Facial Hemiatrophy

Drugs for Facial Hemiatrophy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Ginger Approved

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Potential of Mesenchymal Stem Cell Enriched Adipose Tissue Grafting for Contour Deformities of Face Unknown status NCT02494752
2 Preliminary Investigation of the Effect of Human Adipose Tissue-derived Mesenchymal Stem Cell in Progressive Hemifacial Atrophy(Romberg's Disease) Completed NCT01309061
3 A Clinical Trial Evaluating the Efficacy of a Skin Cream Targeting Dermal Fat in Improving the Skin Elasticity of Healthy Volunteers Recruiting NCT04769193

Search NIH Clinical Center for Facial Hemiatrophy

Cochrane evidence based reviews: facial hemiatrophy

Genetic Tests for Facial Hemiatrophy

Anatomical Context for Facial Hemiatrophy

MalaCards organs/tissues related to Facial Hemiatrophy:

40
Skin, Brain, Eye, Bone, Tongue, Heart, Breast

Publications for Facial Hemiatrophy

Articles related to Facial Hemiatrophy:

(show top 50) (show all 624)
# Title Authors PMID Year
1
Autologous fat grafting for the treatment of sclerotic lesions and scars. 61
32819743 2021
2
Magnetic resonance imaging findings in children with Parry-Romberg syndrome and en coup de sabre. 61
33757522 2021
3
Ophthalmic changes in patients with hemifacial atrophy (Parry-Romberg syndrome). 61
33051768 2021
4
Usefulness of cutaneous ultrasound in the management of Parry Romberg syndrome. 61
33638229 2021
5
Lipofilling as an aesthetic restorative technique for the facial hemiatrophy of Parry-Romberg syndrome: An analysis of 27 cases. 61
33460886 2021
6
Multimodal Imaging of Parry Romberg Syndrome-associated Panuveitis: A Case Report and Review of Literature. 61
31577463 2021
7
Tendon elongation with bovine pericardium in strabismus surgery-indications beyond Graves' orbitopathy. 61
32949299 2021
8
Parry-Romberg syndrome: a mini review. 61
33348939 2020
9
Stent-Assisted Coiling of a Sidewall Aneurysm of the Distal Middle Cerebral Artery: 2-Dimensional Operative Video. 61
33316814 2020
10
Characterization of dental phenotypes and treatment modalities in Korean patients with Parry-Romberg syndrome. 61
33144530 2020
11
To wait or not for stabilization of disease progression before asymmetry correction in Parry-Romberg syndrome. 61
32767412 2020
12
Secukinumab treatment of Parry-Romberg syndrome. 61
32995450 2020
13
Unilateral Neuroimaging Findings in Pediatric Craniofacial Scleroderma: Parry-Romberg Syndrome and En Coup de Sabre. 61
32527172 2020
14
A retrospective study on clinical subtypes and management of morphea in 10 Italian Dermatological Units. 61
33070566 2020
15
Parry–Romberg syndrome 61
32609626 2020
16
Visual Dermatology: Intraoral Examination in Parry Romberg Syndrome. 61
32579401 2020
17
Parry-Romberg syndrome treated with injectable poly-L-lactic acid and hyaluronic acid filler: a case report. 61
32009255 2020
18
Parry Romberg syndrome: Imaging features in 4 consecutive cases and review of literature. 61
32317188 2020
19
Progressive hemifacial atrophy or Parry-Romberg syndrome: A pediatric case report. 61
32428924 2020
20
Anti-GAD epileptic encephalopathy in a toddler with Parry-Romberg syndrome. 61
31828676 2020
21
Parry-Romberg Syndrome With Hemimasticatory Spasm: A Rare Combination. 61
31977713 2020
22
Comprehensive Three-Dimensional Technology Strategies for Autologous Free Fat Graft in Parry-Romberg Syndrome: Comment. 61
31934981 2020
23
Autologous fat transfer for facial recontouring in Parry-Romberg syndrome. 61
31301095 2020
24
Challenging Traditional Thinking: Early Free Tissue Transfer for Active Hemifacial Atrophy in Children. 61
31985645 2020
25
Upper Lip Fat Grafting Using the Anatomical Subunit and Fat Compartment Principles Improves Lip Cant and Symmetry in Patients With Unilateral Upper Lip Asymmetries. 61
31688118 2020
26
A case of overlapping adult-onset linear scleroderma and Parry-Romberg syndrome presenting with widespread ipsilateral neurogenic involvement. 61
31775183 2020
27
Comprehensive Three-Dimensional Technology Strategies for Autologous Free Fat Graft in Parry-Romberg Syndrome. 61
31469732 2020
28
A Case Report of Parry-Romberg Syndrome Misdiagnosed as Multiple Sclerosis. 61
32903543 2020
29
Silent Sinus Syndrome: Interesting Computed Tomography and Magnetic Resonance Imaging Findings. 61
32637229 2020
30
Parry-Romberg syndrome in an adolescent: a case report on progressive hemifacial atrophy. 61
32038874 2020
31
Epilepsy in paediatric patients with Parry-Romberg syndrome: A review of the literature. 61
32044693 2020
32
Parry-Romberg Syndrome and Temporal Lobe Refractory Epilepsy: Case Report. 61
32509553 2019
33
Acquired monocular elevation deficit in a case of Parry-Romberg syndrome. 61
31621456 2019
34
Isolated Fat Grafting for Reconstruction of Lower Face Volumetric Asymmetry in Skeletally Immature Patients: A Clinical Outcome Study. 61
31232814 2019
35
Parry Romberg Syndrome. 61
31741927 2019
36
Multi-vessel coronary artery aneurysms in a patient with Parry Romberg syndrome: a case report. 61
31660479 2019
37
Parry Romberg Syndrome: A Unique Clinico-radiological Entity. 61
31512642 2019
38
The development of multiple ocular complications in a patient with Parry-Romberg syndrome. 61
30467888 2019
39
Parry-Romberg syndrome in Kuwait. Neurological manifestations in 2 children. 61
31287134 2019
40
Craniofacial bone atrophy in Parry Romberg syndrome demonstrated using a Bayesian hierarchical model. 61
31030853 2019
41
Parry Romberg Syndrome: Literature Review and Report of Three Cases. 61
30996540 2019
42
Paranasal Fat Grafting Improves the Nasal Symmetry in Patients With Parry-Romberg Syndrome. 61
30839470 2019
43
Parry-Romberg syndrome associated with en coup de sabre in a patient from South Sudan - a rare entity from East Africa: a case report. 61
31046814 2019
44
Viral encephalitis in Parry-Romberg syndrome. 61
31064793 2019
45
Retinal Vasculitis With Coats-Like Response in a Young Girl With Parry-Romberg Syndrome. 61
31124919 2019
46
Retinal vasculitis the first clue in the diagnosis of progressive hemifacial atrophy. 61
31329538 2019
47
A case of bilateral Parry-Romberg syndrome successfully treated with hyaluronic acid filler augmentation. 61
30985058 2019
48
Parry Romberg Syndrome. 61
30851754 2019
49
Parry-Romberg syndrome and morphoea en coup de sabre. 61
29572218 2019
50
Adult-onset bilateral Parry-Romberg syndrome. 61
30809561 2019

Variations for Facial Hemiatrophy

Expression for Facial Hemiatrophy

Search GEO for disease gene expression data for Facial Hemiatrophy.

Pathways for Facial Hemiatrophy

GO Terms for Facial Hemiatrophy

Sources for Facial Hemiatrophy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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