Aliases & Classifications for Facial Neuralgia

MalaCards integrated aliases for Facial Neuralgia:

Name: Facial Neuralgia 12 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13865
MeSH 43 D005156
UMLS 71 C0015467

Summaries for Facial Neuralgia

MalaCards based summary : Facial Neuralgia is related to trigeminal neuralgia and cranial neuralgia, and has symptoms including neuralgia and facial pain. An important gene associated with Facial Neuralgia is LAPTM4A (Lysosomal Protein Transmembrane 4 Alpha). The drugs Dopamine and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include bone, cortex and trigeminal ganglion, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Facial Neuralgia

Graphical network of the top 20 diseases related to Facial Neuralgia:



Diseases related to Facial Neuralgia

Symptoms & Phenotypes for Facial Neuralgia

UMLS symptoms related to Facial Neuralgia:


neuralgia, facial pain

GenomeRNAi Phenotypes related to Facial Neuralgia according to GeneCards Suite gene sharing:

26 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-130 9.4 DPM1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.4 MBD1
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.4 DPM1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-160 9.4 DPM1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.4 MBD1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.4 DPM1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-187 9.4 DPM1 MBD1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.4 MBD1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.4 DPM1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.4 DPM1
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-98 9.4 MBD1

Drugs & Therapeutics for Facial Neuralgia

Drugs for Facial Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
2
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
3
Prochlorperazine Approved, Vet_approved Phase 3 1984-02-6, 58-38-8 4917
4 Anesthetics, Local Phase 3
5 Tranquilizing Agents Phase 3
6 Neurotransmitter Agents Phase 3
7 Anti-Arrhythmia Agents Phase 3
8 Gastrointestinal Agents Phase 3
9 Dopamine Agents Phase 3
10 Antipsychotic Agents Phase 3
11 Antiemetics Phase 3
12 Dopamine Antagonists Phase 3
13 Anesthetics Phase 3
14 Sodium Channel Blockers Phase 3
15 Psychotropic Drugs Phase 3
16 Central Nervous System Depressants Phase 3
17 Autonomic Agents Phase 3
18 Diuretics, Potassium Sparing Phase 3
19
Topiramate Approved Phase 2 97240-79-4 5284627
20
Guaifenesin Approved, Investigational, Vet_approved Phase 2 93-14-1 3516
21
Dextromethorphan Approved Phase 2 125-71-3 5360696 5362449
22 Hypoglycemic Agents Phase 2
23 Respiratory System Agents Phase 2
24 Anticonvulsants Phase 2
25 Chlorpheniramine, phenylpropanolamine drug combination Phase 2
26 Antitussive Agents Phase 2
27 Excitatory Amino Acid Antagonists Phase 2
28 Excitatory Amino Acids Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Sphenopalatine Ganglion Block for Treating Acute Frontal Migraine Headache in Pediatric Patients Recruiting NCT03984045 Phase 3 Lidocaine topical;Prochlorperazine Injection
2 Clinical Trials in Orofacial Neuralgias Completed NCT00001725 Phase 2 Dextromethorphan
3 A Randomized Clinical Trial of the Effect of Low Level Laser Therapy in Myofacial Pain Syndrome Unknown status NCT01417637
4 Treatment of Chronic Myofascial Pain Syndrome Over Neck by Using Intravascular Laser Irradiation of Blood Unknown status NCT02470000
5 Is Low-level Laser on Traditional Acupoint as Effective as That on Trigger Point in the Management of Cervical Myofascial Pain Syndrome? Completed NCT01516502
6 A Comparative Study of Two Dry Needling Interventions for Plantar Heel Pain: A Randomized Clinical Trial Active, not recruiting NCT03236779
7 CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap Withdrawn NCT01932255

Search NIH Clinical Center for Facial Neuralgia

Cochrane evidence based reviews: facial neuralgia

Genetic Tests for Facial Neuralgia

Anatomical Context for Facial Neuralgia

MalaCards organs/tissues related to Facial Neuralgia:

40
Bone, Cortex, Trigeminal Ganglion

Publications for Facial Neuralgia

Articles related to Facial Neuralgia:

(show top 50) (show all 265)
# Title Authors PMID Year
1
Clinical assessment, diagnosis and management of patients with unilateral sinonasal disease. 61
31349894 2020
2
Orofacial neuralgia associated with a middle cerebral artery aneurysm. 61
30525205 2019
3
Trigeminal hypertrophic interstitial neuropathy presenting as unilateral proptosis, ptosis, tearing, and facial neuralgia. 61
30302419 2018
4
Morphological variations of lingula and prevalence of accessory mandibular foramina in mandibles: A study. 61
30546225 2018
5
Botulinum toxin for facial neuralgia. 61
29930362 2018
6
Other facial neuralgias. 61
28133989 2017
7
Clinical analysis and surgical treatment of trigeminal neuralgia caused by vertebrobasilar dolichoectasia: A retrospective study. 61
28392449 2017
8
Abducent nerve palsy after microballoon compression of the trigeminal ganglion: Case report. 61
28713629 2017
9
Eagle's syndrome veiling as pain of odontogenic origin: Report of two cases with cone beam computed tomography illustration. 61
27390501 2015
10
Sphenopalatine ganglion electrical nerve stimulation implant for intractable facial pain. 61
26000687 2015
11
Ophthalmic branch radiofrequency thermocoagulation for atypical trigeminal neuralgia:a case report. 61
26722633 2015
12
Microvascular decompression of the posterior inferior cerebellar artery for intermediate nerve neuralgia. 61
25883844 2015
13
Successful Management of Refractory Headache and Facial Pain due to Cavernous Sinus Meningioma with Sphenopalatine Ganglion Radiofrequency. 61
25343051 2014
14
Characteristics of neurovascular compression in facial neuralgia patients by 3D high-resolution MRI and fusion technology. 61
23199722 2012
15
Characterization of neurovascular compression in facial neuralgia patients by 3D high-resolution MRI and image fusion technique. 61
22575982 2012
16
Microendoscopic stereotactic-guided percutaneous radiofrequency trigeminal nucleotractotomy. 61
21999320 2012
17
[Neurotrophic ulceration following thermocoagulation of the Gasserian ganglion]. 61
21958840 2011
18
Virtual reality imaging technique in percutaneous radiofrequency rhizotomy for intractable trigeminal neuralgia. 61
19150598 2009
19
[Atypical neuroleptics in the treatment of atypical facial neuralgia. Two case reports]. 61
17786865 2007
20
[Naevus of Ota and idiopathic facial neuralgia: association or coincidence?]. 61
17384554 2007
21
Trigeminal neuralgia. 61
16700659 2006
22
[Drug-induced refractory arterial hypertension]. 61
16323733 2005
23
[Medication, steel or radiation? The appropriate strategy to treat facial neuralgia]. 61
15957859 2005
24
Midfacial segment pain: implications for rhinitis and sinusitis. 61
15056400 2004
25
Peripheral glycerol injection for the relief of facial neuralgia in children. 61
14687685 2004
26
[Trigeminal neuralgia presenting as a deep recurrent desmoplastic neurotropic melanoma of a lentigo maligna]. 61
14724540 2003
27
Oral and maxillofacial surgery in patients with chronic orofacial pain. 61
12796872 2003
28
Motor cortex stimulation for neuropathic facial pain. 61
12635515 2003
29
[Essential facial neuralgia with bilateral involvement: apropos of a case seen at the Cité Verte Hospital in Yaoundé]. 61
12430349 2002
30
[Oral pain]. 61
11944550 2002
31
[Flat angioma and idiopathic facial neuralgia. Association or coincidence?]. 61
11908144 2001
32
Electrical stimulation of the trigeminal tract in chronic, intractable facial neuralgia. 61
11935364 2001
33
Headache management in an interventional pain practice. 61
16906198 2000
34
"A right-sided facial neuralgia": or fragmenting the history of the "Dora" manuscript. 61
10672625 1999
35
Maxillofacial osteonecrosis in a patient with multiple "idiopathic" facial pains. 61
10535367 1999
36
Ischemic osteonecrosis under fixed partial denture pontics: radiographicand microscopic features in 38 patients with chronic pain. 61
9922427 1999
37
[Extracranial trigeminal schwannomas with middle temporal fossa development]. 61
9757316 1998
38
[Chronic paroxysmal hemicrania]. 61
9498856 1997
39
Epidural electrical stimulation of the motor cortex in patients with facial neuralgia. 61
9350402 1997
40
[Facial neuralgia (neuralgia n. V). Diagnosis and treatment]. 61
9380814 1997
41
[Syncope associated with glossopharyngeal neuralgia and parapharyngeal tumor]. 61
9036496 1996
42
Thrombophilia, hypofibrinolysis, and alveolar osteonecrosis of the jaws. 61
8734702 1996
43
[Thermocoagulation in the treatment of facial neuralgia. Preliminary results in 22 cases]. 61
9289499 1996
44
Long-term effects of jawbone curettage on the pain of facial neuralgia. 61
7699492 1995
45
Facial neuralgia cured by acupuncture a century and a half ago. 61
8696151 1995
46
Endoscopy of the cerebellopontine angle. 61
7569371 1995
47
Atypical facial "neuralgia". 61
7802278 1995
48
[Low reactive-level laser therapy near the stellate ganglion for postherpetic facial neuralgia]. 61
1334163 1992
49
[Cranio-facial neuralgia and problems in oral medicine. Value of a multidisciplinary approach]. 61
1461409 1992
50
Facial neuralgias: a clinical review of 34 cases. 61
1333878 1992

Variations for Facial Neuralgia

Expression for Facial Neuralgia

Search GEO for disease gene expression data for Facial Neuralgia.

Pathways for Facial Neuralgia

GO Terms for Facial Neuralgia

Sources for Facial Neuralgia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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