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MCID: FCL012
MIFTS: 53

Facial Paralysis

Categories: Neuronal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Facial Paralysis

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MalaCards integrated aliases for Facial Paralysis:

Name: Facial Paralysis 12 75 44 15 72
Facial Palsy 12 15
Bell Palsy 72

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:13934
MeSH 44 D005158
NCIt 50 C26769
ICD10 33 G51.0
UMLS 72 C0015469 C0376175
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Summaries for Facial Paralysis

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MalaCards based summary : Facial Paralysis, also known as facial palsy, is related to bell's palsy and camurati-engelmann disease, and has symptoms including seizures, muscle weakness and tremor. An important gene associated with Facial Paralysis is LIPN (Lipase Family Member N), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and Primary immunodeficiency. The drugs Acetylcholine and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and eye, and related phenotypes are cellular and endocrine/exocrine gland

Wikipedia : 75 Facial nerve paralysis is a common problem that involves the paralysis of any structures innervated by... more...

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Related Diseases for Facial Paralysis

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Diseases related to Facial Paralysis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 592)
# Related Disease Score Top Affiliating Genes
1 bell's palsy 34.1 LIPN HOXB1
2 camurati-engelmann disease 32.7 TGFB1 LRP5
3 acoustic neuroma 31.0 TGFB1 NF2
4 lattice corneal dystrophy 30.1 TGFB1 GSN
5 hyperostosis 29.7 TGFB1 LRP5 ANKH
6 meningioma, radiation-induced 29.7 NF2 CADM1
7 facial nerve disease 26.7 NF2 MARVELD1 LRP5 LIPN HOXB1 GSN
8 facial palsy, congenital, with ptosis and velopharyngeal dysfunction 12.7
9 facial palsy, familial recurrent peripheral 12.5
10 deafness, conductive stapedial, with ear malformation and facial palsy 12.5
11 recurrent peripheral facial palsy 12.4
12 congenital hereditary facial paralysis-variable hearing loss syndrome 12.4
13 aortic arch interruption, facial palsy, and retinal coloboma 12.3
14 anotia facial palsy cardiac defect 12.3
15 urofacial syndrome 1 11.6
16 facial paresis, hereditary congenital, 1 11.6
17 facial paresis, hereditary congenital, 3 11.6
18 melkersson-rosenthal syndrome 11.5
19 moebius syndrome 11.5
20 geniculate herpes zoster 11.4
21 neurilemmoma 11.4
22 carey-fineman-ziter syndrome 11.3
23 craniometaphyseal dysplasia, autosomal dominant 11.2
24 craniometaphyseal dysplasia, autosomal recessive 11.2
25 biotin-thiamine-responsive basal ganglia disease 11.2
26 familial amyloidosis, finnish type 11.2
27 osteopetrosis, autosomal recessive 1 11.1
28 osteopathia striata with cranial sclerosis 11.1
29 thiamine metabolism dysfunction syndrome 2 11.1
30 lethal congenital contracture syndrome 2 11.1
31 sclerosteosis 11.1
32 dandy-walker complex 11.1
33 lattice corneal dystrophy type ii 11.1
34 amyloidosis, finnish type 11.0
35 charge syndrome 11.0
36 pontine tegmental cap dysplasia 11.0
37 charlie m syndrome 11.0
38 otitis media 10.6
39 herpes zoster 10.5
40 lagophthalmos 10.5
41 chickenpox 10.5
42 cholesteatoma of middle ear 10.5
43 lyme disease 10.4
44 herpes simplex 10.4
45 branchiootic syndrome 1 10.4
46 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.4
47 pustulosis palmaris et plantaris 10.4 TGFB1 CD40LG
48 ptosis 10.4
49 gingival disease 10.4 TGFB1 ANTXR2
50 myoclonus and ataxia 10.3

Comorbidity relations with Facial Paralysis via Phenotypic Disease Network (PDN):


Acute Cystitis Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Exposure Keratitis Hypertension, Essential
Mechanical Ectropion Myoclonus and Ataxia
Paralytic Lagophthalmos Parotid Gland Cancer
Swallowing Disorders Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Facial Paralysis:



Diseases related to Facial Paralysis
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Symptoms & Phenotypes for Facial Paralysis

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UMLS symptoms related to Facial Paralysis:


seizures, muscle weakness, tremor, generalized muscle weakness, back pain, ophthalmoplegia, pain, headache, hemiplegia, syncope, chronic pain, sciatica, vertigo/dizziness, sleeplessness, oral manifestations, facial paresis, facial palsy, upper motor neuron, facial palsy, lower motor neuron, hemifacial paralysis, flaccid muscle tone

MGI Mouse Phenotypes related to Facial Paralysis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.13 ANKH ANTXR2 CADM1 CD4 CD40LG CD82
2 endocrine/exocrine gland MP:0005379 10.01 CADM1 CD4 CD40LG GSN HOXB1 LRP5
3 cardiovascular system MP:0005385 10 ANKH ANTXR2 CD40LG CD82 GSN LRP5
4 hematopoietic system MP:0005397 9.97 ANKH CADM1 CD4 CD40LG GSN HOXB1
5 homeostasis/metabolism MP:0005376 9.97 ANKH CD4 CD40LG CD82 GSN LIPN
6 immune system MP:0005387 9.96 ANKH ANTXR2 CADM1 CD4 CD40LG GSN
7 nervous system MP:0003631 9.76 CADM1 CD4 CD40LG GSN HOXB1 LRP5
8 reproductive system MP:0005389 9.5 ANKH ANTXR2 CADM1 CD40LG GSN NF2
9 skeleton MP:0005390 9.17 ANKH CD40LG GSN HOXB1 LRP5 NF2
Sources

Drugs & Therapeutics for Facial Paralysis

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Drugs for Facial Paralysis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 58)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
3
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
4
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
5
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
6
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
7
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
8
Cortisone Experimental Phase 4 53-06-5 222786
9 Neurotransmitter Agents Phase 4
10 abobotulinumtoxinA Phase 4
11 Cholinergic Agents Phase 4
12 Neuromuscular Agents Phase 4
13 Acetylcholine Release Inhibitors Phase 4
14 Botulinum Toxins Phase 4
15 Botulinum Toxins, Type A Phase 4
16 Anti-Infective Agents Phase 4
17 Antiviral Agents Phase 4
18 valacyclovir Phase 4
19 incobotulinumtoxinA Phase 4
20 Neuroprotective Agents Phase 4
21 Methylprednisolone Acetate Phase 4
22 Protective Agents Phase 4
23 Prednisolone acetate Phase 4
24 Peripheral Nervous System Agents Phase 4
25 Anesthetics, Local Phase 4
26 Sodium Channel Blockers Phase 4
27 Diuretics, Potassium Sparing Phase 4
28 Central Nervous System Depressants Phase 4
29 Anti-Arrhythmia Agents Phase 4
30 Anesthetics Phase 4
31
Prednisone Approved, Vet_approved Phase 2, Phase 3 53-03-2 5865
32
Dexamethasone Approved, Investigational, Vet_approved Phase 2, Phase 3 50-02-2 5743
33
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2, Phase 3 1177-87-3
34
tannic acid Approved Phase 2, Phase 3 1401-55-4
35
Phenol Approved, Experimental Phase 2, Phase 3 108-95-2 996
36
Benzocaine Approved, Investigational Phase 2, Phase 3 94-09-7, 1994-09-7 2337
37 Antiemetics Phase 2, Phase 3
38 Anti-Inflammatory Agents Phase 2, Phase 3
39 Hormones Phase 2, Phase 3
40 Gastrointestinal Agents Phase 2, Phase 3
41 glucocorticoids Phase 2, Phase 3
42 Antineoplastic Agents, Hormonal Phase 2, Phase 3
43 Hormone Antagonists Phase 2, Phase 3
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3
45 Autonomic Agents Phase 2, Phase 3
46 Pharmaceutical Solutions Phase 2, Phase 3
47 BB 1101 Phase 2, Phase 3
48 alpha-methyltyrosine Phase 2
49
Salicylic acid Approved, Investigational, Vet_approved 69-72-7 338
50
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189

Interventional clinical trials:

(show top 50) (show all 64)
# Name Status NCT ID Phase Drugs
1 A Multicentre Placebo-Controlled Evaluation of Prednisolone and/or Valaciclovir for the Treatment of Bell's Palsy Completed NCT00510263 Phase 4 Prednisolone + placebo;Valaciclovir + placebo;Prednisolone + valaciclovir;Placebo + placebo
2 Randomized, Single-blind Comparison of Three Commercially Available Botulinum Neuromodulators in the Management of Facial Synkinesis Completed NCT03048383 Phase 4 OnabotulinumtoxinA Injectable Product;AbobotulinumtoxinA Injectable Product;Incobotulinumtoxin A Injectable Product
3 The Facial Nerve Palsy And Cortisone Evaluation (FACE) Study in Children: A Randomized Double-blind, Placebo-controlled, Multicenter Trial Recruiting NCT03781700 Phase 4 Prednisolone;Placebo Oral Tablet
4 Study of the Reinnervation of Facial Muscles After Lengthening Temporalis Myoplasty Terminated NCT01833221 Phase 4 injection of 1% lidocaine, 2mL for facial nerve block
5 Assessment of Corticosteroid Effect in the Prevention of Facial Palsy After Cerebella-pontine Angle Surgery Completed NCT00438087 Phase 3 methylprednisolone
6 Intratympanic Steroid Injection for Treatment of Idiopathic Facial Nerve Paralysis Recruiting NCT03508440 Phase 2, Phase 3 Prednisone
7 A Double-Blind, Placebo-Controlled, Multi-Center, Randomized Trial of the Safety and Efficacy of Metyrosine (Demser®) for the Treatment of Psychotic Disorders in Patients With Velo-Cardio-Facial Syndrome Terminated NCT01127503 Phase 2 Metyrosine;Placebo
8 Study of Psychological Factors on the Occurence of Bell's Palsy Unknown status NCT01377766
9 Prednisone Acetate and Acupuncture for the Treatment of Facial Neuritis: a Multiple Center, Comparative Effectiveness Research in China Unknown status NCT01201642 Prednisolone
10 Quantification, Analysis and Simulation of Facial Mimics Movements Unknown status NCT02002572
11 Cognitive and Physical Functions in Patients With TIA. A Randomized Controlled Trial of Physical Activity on Prescription up to One Year After the Event Unknown status NCT01509924
12 Prospective Randomized Study Comparing Clinical, Functional and Aesthetics Results of "Classical" Pterional and Minipterional Craniotomies. Unknown status NCT01872741
13 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
14 Assessment of the Cross-face Nerve Graft in the Treatment of Facial Paralysis Completed NCT03006783
15 Complications in Parotid Surgery - a Prospective Cohort Study Completed NCT02486393
16 Improvement of Facial Symmetry With Myofunctional Therapy Combined to Botulinum Toxin Injections in Long Standing Facial Paralysis Completed NCT00989209 Botulinum Toxin Type A
17 Antiviral Treatment in Facial Palsy. Randomized Control Trial Completed NCT02328079 Steroids (Prednisolone) and Steroids plus Antiviral (Prednisolone + acyclovir)
18 Pilot Study Assessing Cognitive Function and Emotional Possessing in Patients With Bilateral Facial Palsy Completed NCT02179450
19 Studying of Acupuncture for Bell's Palsy According to Different Stages Completed NCT00608660
20 Anthropometric Angular Measurement to Determine Muscle Tonus in Patients With Peripheral Facial Paralysis Completed NCT00903669
21 Post-parotidectomy Facial Paresis: Intraoperative and Postoperative Factors Completed NCT02527226
22 Neuro Occlusal Rehabilitation in Patient With Peripheral Facial Paralysis - a Randomized Clinical Trial Completed NCT01327157
23 Function and Form Outcomes in Patients With Facial Paralysis Completed NCT03974763
24 Study of Effects of Deqi and Neuropsychological Factors on Acupuncture Effects in Treatment of Bell's Palsy Completed NCT00685789
25 The Role of MyotonPro in Assessing the Biomechanical Properties of Facial Muscles in Facial Paralysis Patients and Its Role in Monitoring Recovery Following Facial Reanimation Surgery Completed NCT02489162
26 Non-surgical Correction of Eye Lid Paralysis With External Magnet Systems Completed NCT02988856
27 A New Clinical Therapy for Bell's Palsy Completed NCT01686464 prednisone and valacyclovir treatments
28 Treatment Bell´s Palsy: Prednisone vs Prednisone Valacyclovir Completed NCT00561106 prednisone- valacyclovir;prednisone-placebo
29 Retrospective Clinical Outcome of Parotid Tumor Surgery Completed NCT01983176
30 Clinical Research Core Dental Screening Protocol Completed NCT00090818
31 Exploration of the Diagnostic Capabilities of Ultrasound of the Oropharynx and Larynx Completed NCT00001167
32 Validation of Prehospital Stroke Scale (FAST PLUS TEST) to Predict Patients With Large Arterial Vessel Intracranial Occlusion. Completed NCT03072524
33 Exploration and Estimation of Intratumoral Concentration and Activity of Lapatinib in Vivo in Vestibular Schwannomas Completed NCT00863122 Early Phase 1 lapatinib
34 Assessment Effects of Somatosensorial and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke Completed NCT03477188
35 Iowa/Nucleus 10/10 mm and Nucleus Freedom Cochlear Implants Implanted Bilaterally in Children Ages 12-24 Months Completed NCT00594061
36 Pilot Clinical Trial to Study Facial Electrical Stimulation to Promote Recovery in Patients With Bell's Palsy and Poor Prognostic Factors Recruiting NCT03836989
37 Comparative Study of Peripheral Facial Paralysis Sequelae Based on the Initial Medical Care of Lyme Disease Among Children Recruiting NCT03981874
38 A Pilot Study Evaluating the Effectiveness of Information and Therapy Guides for Improving the Psychosocial Wellbeing of People With Facial Palsy. Recruiting NCT03943953
39 Production et Perception émotionnelle Chez Les Patients paralysés Faciaux: Marqueurs Respiratoires, Phonatoires et expressivité Faciale. Recruiting NCT03619720
40 Lengthening Temporalis Myoplasty and Improvement of Primary Swallowing Disorders in Facial Paralysis Recruiting NCT03284125
41 Validation of a French-language Version of Specific Quality of Life Questionnaires in Patients With Peripheral Facial Palsy Recruiting NCT03581253
42 Morphometric Study of the Muscles of the Skin in MRI 3 Tesla in Patients With Facial Paralysis. Recruiting NCT03115203
43 Reliability of Multislice Computed Tomography Scan in Cases With Facial Nerve Paralysis Due to Temporal Bone Trauma Recruiting NCT03469427
44 Effect of Laser Acupuncture Treatment on Chronic Facial Paralysis: A Randomized Sham Control, Double Blind Pilot Study Recruiting NCT03592797
45 Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies Recruiting NCT03059420
46 Imaging of Facial Neuritis Using T2-weighted Gradient-echo Fast Imaging Employing Steady State Acquisition After Gadolinium Injection Recruiting NCT03543384
47 Postoperative Facial Weakness in Parotidectomy for Deep Seated Parotid Tumor With or Without Intra-parotid Facial Nerve Imaging (3D Double-Echo Steady-State With Water Excitation MRI Imaging) Recruiting NCT03822728
48 Screening and Characterization of Hearing Disorders in Diabetic Persons. Recruiting NCT03437135
49 Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders Recruiting NCT02055248
50 Advanced Diagnostics of Acute Stroke (Biomarkers, Blood Analysis, Stroke Scales and Cerebral CT Examinations) and Initiation of rtPa Treatment in an Air Ambulance Model Recruiting NCT03158259

Search NIH Clinical Center for Facial Paralysis

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Scopolamine
Scopolamine Hydrobromide

Cochrane evidence based reviews: facial paralysis

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Genetic Tests for Facial Paralysis

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Anatomical Context for Facial Paralysis

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MalaCards organs/tissues related to Facial Paralysis:

41
Bone, Testes, Eye, Brain, Skin, Salivary Gland, Myeloid
Sources

Publications for Facial Paralysis

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Articles related to Facial Paralysis:

(show top 50) (show all 8085)
# Title Authors PMID Year
1
Contrast-enhanced magnetic resonance imaging of facial nerve swelling in patients with severe Ramsay Hunt syndrome. 38
30630650 2019
2
Vestibular Schwannoma Resection in a Consecutive Series of 502 Cases via the Retrosigmoid Approach: Technical Aspects, Complications, and Functional Outcome. 38
31100515 2019
3
Missed Culprits in Failed Microvascular Decompression Surgery for Hemifacial Spasm and Clinical Outcomes of Redo Surgery. 38
31158550 2019
4
Medulloblastomas in cerebellopontine angle: Epidemiology, clinical manifestations, imaging features, molecular analysis and surgical outcome. 38
31239198 2019
5
Guillain-Barre syndrome and its correlation with dengue, Zika and chikungunya viruses infection based on a literature review of reported cases in Brazil. 38
31220435 2019
6
Bilateral facial paralysis as a rare neurological manifestation of primary Sjögren's syndrome: case-based review. 38
31175417 2019
7
Iatrogenic facial nerve exposure in cochlear implant surgery: incidence and clinical significance in the absence of intra-operative nerve monitoring. 38
31188716 2019
8
Otorrhoea with facial palsy in a child. 38
29858271 2019
9
Meta-analysis of Delayed Facial Palsy Following Middle Ear Surgery. 38
31356488 2019
10
Combined delivery of VEGF and IGF-1 promotes functional innervation in mice and improves muscle transplantation in rabbits. 38
31203034 2019
11
Using the "Sugarcane Chewing" Concept as the Directionality of Motor Neurotizer Selection for Facial Paralysis Reconstruction: Chang Gung Experiences. 38
31348359 2019
12
Effectiveness and safety of the use of gracilis muscle for dynamic smile restoration in facial paralysis: A systematic review and meta-analysis. 38
31204152 2019
13
Recurrent and Progressive Facial Baroparesis on Flying Relieved by Eustachian Tube Dilation. 38
30895801 2019
14
The evolving roles of computer-based technology and smartphone applications in facial plastic surgery. 38
31157662 2019
15
Short-term versus long-term outcomes of microvascular decompression for hemifacial spasm. 38
31392569 2019
16
Cephalic tetanus presenting with bilateral facial palsy. 38
30866747 2019
17
Clinical and electrophysiological characteristics of Guillain-Barré syndrome in Colombia. 38
31386254 2019
18
Depression Rates After Facial Paralysis. 38
31232802 2019
19
Infant Facial Paralysis Associated with Epstein-Barr Virus Infection. 38
31420529 2019
20
Facial reanimation: an update on nerve transfers in facial paralysis. 38
31169528 2019
21
Case report: Recurrent peripheral facial paralysis following two influenza vaccinations in 2009 and 2016. 38
31311685 2019
22
A Modified Technique of Transposition of Temporalis Muscle in Selected Cases of Longstanding Facial Paralysis. 38
31403508 2019
23
[Isolated Peripheral Facial Palsy Due to Dorsal Pontine Infarction]. 38
31346148 2019
24
Bilateral facial palsy. 38
31430217 2019
25
Childhood Facial Palsy: Etiologic Factors and Clinical Findings, an Observational Retrospective Study. 38
31407620 2019
26
In the Eye of the Beholder: Changes in Perceived Emotion Expression after Smile Reanimation. 38
31348360 2019
27
Patient experience in nerve-to-masseter-driven smile reanimation. 38
31060989 2019
28
Desmoid-type fibromatosis of the head and neck in children: A changing situation. 38
31059930 2019
29
Surgical denervation of Platysma bands: A Novel technique in rhytidectomy. 38
31373989 2019
30
Kimura's Disease. 38
31299798 2019
31
One-stage reconstruction by dual-innervated double muscle flap transplantation with the neural interconnection between the ipsilateral masseter and contralateral facial nerve for reanimating established facial paralysis: A report of 2 cases. 38
30512222 2019
32
Endoscope-assisted retrosigmoid approach in hemifacial spasm: our experience. 38
29784621 2019
33
Long-term Outcomes of Microvascular Decompression in the Treatment of Hemifacial Spasm Based on Different Offending Vessels. 38
31018226 2019
34
[Clinical value of V-shaped concealed incision in parotid benign tumors]. 38
31327198 2019
35
Bilateral Internal Auditory Canal Metastasis of Colon Carcinoma Mimicking Neurofibromatosis Type II: A Case Report and Literature Review. 38
30862585 2019
36
A rare case of unilateral hemifacial spasm and facial palsy associated with an abnormal anatomical variant of the posterior basilar circulation. 38
31155905 2019
37
Atypical clinical manifestations of herpes zoster oticus: diagnostic usefulness of magnetic resonance imaging. 38
31278535 2019
38
Children with facial paralysis due to Moebius syndrome exhibit reduced autonomic modulation during emotion processing. 38
31291910 2019
39
Cochlear implantation via middle fossa approach - a case report. 38
30741118 2019
40
Congenital monocular elevation deficiency associated with a novel TUBB3 gene variant. 38
31302631 2019
41
Facial Nerve Hematoma After Penetrating Middle Ear Trauma: A Cause of Delayed Facial Palsy. 38
31356480 2019
42
The Price of Immune Responses and the Role of Vitamin D in the Inner Ear. 38
31194714 2019
43
[A case of tuberculous meningitis with pleural effusion as a manifestation of a paradoxical reaction during anti-tuberculosis therapy]. 38
31341131 2019
44
Initial National Institute of Health Stroke Scale to Early Predict the Improvement of Swallowing in Patients with Acute Ischemic Stroke. 38
31358355 2019
45
Cryptococcal meningitis presenting as acute flaccid paralysis: A case report. 38
31350098 2019
46
Atypical "nine" syndrome in bilateral pontine infarction: A case report. 38
31305438 2019
47
[Transmastoidslotted labyrinthotomy approach cochlear implantation with customized electrode for patients with common cavity deformity]. 38
31315354 2019
48
Petrous bone cholesteatoma: our experience of 51 patients with emphasis on cochlea preservation and use of endoscope. 38
31050582 2019
49
Facial paralysis of unknown etiology. 38
30905374 2019
50
Role of IV Immunoglobulin in Indian Children With Guillain-Barré Syndrome. 38
30985608 2019
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Variations for Facial Paralysis

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Expression for Facial Paralysis

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Search GEO for disease gene expression data for Facial Paralysis.
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Pathways for Facial Paralysis

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Pathways related to Facial Paralysis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Cell adhesion molecules (CAMs) 37
10.96 CD40LG CD4 CADM1
2
Primary immunodeficiency 37
10.89 CD40LG CD4
3
N-cadherin signaling events 1
10.78 LRP5 GSN
4
Cytokines and Inflammatory Response 1
10.62 TGFB1 CD4
5
IL12 signaling mediated by STAT4 1
10.4 TGFB1 CD4
Sources

GO Terms for Facial Paralysis

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Cellular components related to Facial Paralysis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.36 TGFB1 NF2 MARVELD1 LRP5 GSN CD82

Biological processes related to Facial Paralysis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell differentiation GO:0030217 9.4 TGFB1 CD4
2 toxin transport GO:1901998 9.37 LRP5 ANTXR2
3 oligodendrocyte development GO:0014003 9.32 TGFB1 GSN
4 cell-cell junction organization GO:0045216 9.26 TGFB1 NF2
5 response to vitamin D GO:0033280 9.16 TGFB1 CD4
6 negative regulation of cell-cell adhesion GO:0022408 8.96 TGFB1 NF2
7 lens fiber cell differentiation GO:0070306 8.62 TGFB1 NF2
Sources

Sources for Facial Paralysis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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