Aliases & Classifications for Facial Spasm

MalaCards integrated aliases for Facial Spasm:

Name: Facial Spasm 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
facial spasm:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 56 134300
MedGen 41 C0278151
SNOMED-CT via HPO 68 13045009 263681008 405946002

Summaries for Facial Spasm

MalaCards based summary : Facial Spasm is related to hemifacial spasm, familial and hemifacial spasm. The drugs Prednisolone and Methylprednisolone hemisuccinate have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and pons, and related phenotypes are hyporeflexia and anisocoria

More information from OMIM: 134300

Related Diseases for Facial Spasm

Diseases related to Facial Spasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 hemifacial spasm, familial 10.4
2 hemifacial spasm 10.4
3 trigeminal neuralgia 10.3
4 blepharospasm 10.2
5 ptosis 10.2
6 facial paralysis 10.1
7 tic disorder 10.0
8 dystonia 10.0
9 seizures, benign familial neonatal, 1 9.9
10 arachnoid cysts, intracranial 9.9
11 bell's palsy 9.9
12 glossopharyngeal neuralgia 9.9
13 epilepsy 9.9
14 pathologic nystagmus 9.9
15 myoclonus 9.9
16 strabismus 9.8
17 torticollis 9.8
18 arterial tortuosity syndrome 9.8
19 cervical dystonia 9.8
20 photosensitive epilepsy 9.8
21 tabes dorsalis 9.8
22 spastic entropion 9.8
23 entropion 9.8
24 guillain-barre syndrome 9.8
25 arteriosclerosis 9.8
26 hemangioma 9.8
27 pleomorphic adenoma 9.8
28 movement disease 9.8
29 benign ependymoma 9.8
30 ganglioglioma 9.8
31 cellular ependymoma 9.8
32 adenoma 9.8
33 neuropathy 9.8
34 parotid gland cancer 9.8
35 mechanical strabismus 9.8
36 dysphagia 9.8
37 spasticity 9.8

Graphical network of the top 20 diseases related to Facial Spasm:



Diseases related to Facial Spasm

Symptoms & Phenotypes for Facial Spasm

Human phenotypes related to Facial Spasm:

31
# Description HPO Frequency HPO Source Accession
1 hyporeflexia 31 HP:0001265
2 anisocoria 31 HP:0009916

Symptoms via clinical synopsis from OMIM:

56
Eyes:
anisocoria

Misc:
worsened by cold and excitement

Neuro:
facial nerve spasm
depressed tendon reflexes

Clinical features from OMIM:

134300

Drugs & Therapeutics for Facial Spasm

Drugs for Facial Spasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
2
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
3
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
4 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
5
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
6
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
7 Antiemetics Phase 4
8 Methylprednisolone Acetate Phase 4
9 Gastrointestinal Agents Phase 4
10 Hormone Antagonists Phase 4
11 Neuroprotective Agents Phase 4
12 Anti-Inflammatory Agents Phase 4
13 Antineoplastic Agents, Hormonal Phase 4
14 Autonomic Agents Phase 4
15 Protective Agents Phase 4
16 glucocorticoids Phase 4
17 Hormones Phase 4
18 Anti-Infective Agents Phase 4
19 valacyclovir Phase 4
20 Antiviral Agents Phase 4
21
Levetiracetam Approved Phase 2 102767-28-2 441341
22 Nootropic Agents Phase 2
23 Anticonvulsants Phase 2
24
Prednisone Approved, Vet_approved 53-03-2 5865

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Multicentre Placebo-Controlled Evaluation of Prednisolone and/or Valaciclovir for the Treatment of Bell's Palsy Completed NCT00510263 Phase 4 Prednisolone + placebo;Valaciclovir + placebo;Prednisolone + valaciclovir;Placebo + placebo
2 A Pilot Trial of Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease Completed NCT00324454 Phase 2
3 Prednisone Acetate and Acupuncture for the Treatment of Facial Neuritis: a Multiple Center, Comparative Effectiveness Research in China Unknown status NCT01201642 Prednisolone
4 Taiwan: Institutional Review Board Unknown status NCT02004639

Search NIH Clinical Center for Facial Spasm

Genetic Tests for Facial Spasm

Anatomical Context for Facial Spasm

MalaCards organs/tissues related to Facial Spasm:

40
Bone, Brain, Pons, Lymph Node, Tongue

Publications for Facial Spasm

Articles related to Facial Spasm:

(show top 50) (show all 255)
# Title Authors PMID Year
1
Abnormal brain white matter in patients with hemifacial spasm: a diffusion tensor imaging study. 61
31792569 2019
2
Radiosurgery for Epidermoid Tumors: Dramatic Pain Relief from Trigeminal Neuralgia. 61
31893192 2019
3
Combined hyperactive dysfunction syndrome of the cranial nerves complicated by essential hypertension: A case report. 61
31415413 2019
4
Cerebral abscess following the self-extraction of teeth in patient with Ebstein's anomaly: a case report. 61
31470835 2019
5
A rare case of unilateral hemifacial spasm and facial palsy associated with an abnormal anatomical variant of the posterior basilar circulation. 61
31155905 2019
6
Haemodynamic changes and incisional bleeding after scalp infiltration of dexmedetomidine with lidocaine in neurosurgical patients. 61
30394347 2019
7
[Clinical diagnosis and surgical management of 110 cases of facial nerve schwannomas]. 61
30776861 2019
8
Hemifacial spasm secondary to middle ear cholesteatoma. 61
30036421 2018
9
Botulinum toxin in movement disorders. 61
29503330 2018
10
Bilateral Facial Spasm Following Guillain-Barré Syndrome. 61
29971193 2018
11
Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma. 61
28246588 2017
12
[Comparison of hearing rehabilitation for patients with Mondini malformation after cochlear implantation with different electrodes]. 61
29871243 2017
13
Anti-inflammatory and immune regulatory effects of acupuncture after craniotomy: study protocol for a parallel-group randomized controlled trial. 61
28069040 2017
14
[Comparative observation of the efficacy on facial spasm among different therapies]. 61
29231320 2017
15
Facial Nerve Schwannomas: Review of 80 Cases Over 25 Years at Mayo Clinic. 61
27720200 2016
16
Extracranial Facial Nerve Schwannoma Treated by Hypo-fractionated CyberKnife Radiosurgery. 61
27774363 2016
17
Hemifacial Spasm Associated with Contralateral Foramen Magnum Meningioma. 61
26826538 2016
18
[Microvascular decompression for hemifacial spasm induced by vertebral artery dissecting aneurysm: one case report]. 61
28087915 2016
19
Clinical significance of lesser occipital nerve preservation during micro-vascular decompression for hemi-facial spasm. 61
25564009 2016
20
Microvascular decompression for atypical hemifacial spasm: lessons learned from a retrospective study of 12 cases. 61
26339846 2016
21
Functional facial and tongue movement disorders. 61
27719855 2016
22
Possible sertraline-induced extrapyramidal adverse effects in an adolescent. 61
27226717 2016
23
A Case of Facial Spasm Associated with Ipsilateral Cerebellopontine Angle Arachnoid Cyst. 61
28824969 2015
24
[Clinical observation of fire needle for facial spasm]. 61
26964161 2015
25
Microvascular decompression and MRI findings in trigeminal neuralgia and hemifacial spasm. A single center experience. 61
26519891 2015
26
Efficiency of ultrasound and water capsule-guided local injection of botulinum toxin type A treatment on patients with facial spasm. 61
26044228 2015
27
A case of hemifacial spasm caused by an artery passing through the facial nerve. 61
25810866 2015
28
[Case of primary facial spasm]. 61
25876340 2014
29
Higher dose dexamethasone increases early postoperative cognitive dysfunction. 61
24621831 2014
30
Linear accelerator stereotactic radiosurgery for vestibular schwannomas: a UK series. 61
24636634 2014
31
Continuous intraoperative monitoring of abnormal muscle response in microvascular decompression for hemifacial spasm; a real-time navigator for complete relief. 61
24272304 2014
32
[Ten cases report of vascular compressive syndrome caused by the facial, acoustic nerves]. 61
25026816 2014
33
Pre-induction dexamethasone does not decrease postoperative nausea and vomiting after microvascular decompression for facial spasm. 61
25043094 2014
34
Primary cerebellopontine angle Rathke's cleft cyst: case report. 61
24848188 2014
35
3D CT-guided pulsed radiofrequency treatment for trigeminal neuralgia. 61
23433058 2014
36
Clinical review of the effects of hominis placental pharmacopuncture in the treatment of facial spasm patients. 61
25780676 2013
37
[AICA anatomic variation as a factor of worse prognosis for the surgical treatment of hemi-facial spasm]. 61
23815844 2013
38
Shell shock: Psychogenic gait and other movement disorders-A film review. 61
23538744 2013
39
Long-term follow-up studies of Gamma Knife surgery with a low margin dose for vestibular schwannoma. 61
23205790 2012
40
[Preliminary application of absorbable fixation system on cranial bone flap reposition and fixation after craniotomy]. 61
23167103 2012
41
Effectiveness of acupuncture in treatment of facial spasm: a meta-analysis. 61
22875561 2012
42
Physical therapy for Bell's palsy (idiopathic facial paralysis). 61
22161401 2011
43
Cerebellopontine angle endodermal cyst presenting with hemifacial spasm. 61
21643804 2011
44
[Acupuncture at Governor Vessel points for 50 cases of facial spasm]. 61
22043685 2011
45
Complications and clinical analysis of 416 consecutive cochlear implantations. 61
21741711 2011
46
Hemifacial spasm due to contralateral aneurysmal compression of the facial nerve successfully treated with endovascular coil embolization: case report. 61
21832966 2011
47
Prednisolone and acupuncture in Bell's palsy: study protocol for a randomized, controlled trial. 61
21693007 2011
48
Cerebellopontine angle facial schwannoma relapsing towards middle cranial fossa. 61
24765294 2011
49
Deeper total intravenous anesthesia reduced the incidence of early postoperative cognitive dysfunction after microvascular decompression for facial spasm. 61
21252704 2011
50
Surgical treatment of patients with facial neuromas--a report of 26 consecutive operations. 61
20729780 2010

Variations for Facial Spasm

Expression for Facial Spasm

Search GEO for disease gene expression data for Facial Spasm.

Pathways for Facial Spasm

GO Terms for Facial Spasm

Sources for Facial Spasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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