MCID: FCT008
MIFTS: 31

Factitious Disorder

Categories: Mental diseases

Aliases & Classifications for Factitious Disorder

MalaCards integrated aliases for Factitious Disorder:

Name: Factitious Disorder 12 15
Munchausen Syndrome 12 71
Factitious Disorders 71
Münchausen Syndrome 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1766
ICD9CM 34 300.16
SNOMED-CT 67 430751001
UMLS 71 C0015480 C0015481 C0026785

Summaries for Factitious Disorder

Disease Ontology : 12 A disease of mental health where symptoms are deliberately produced, feigned or exaggerated in order to falsely demonstrate the presence of an illness.

MalaCards based summary : Factitious Disorder, also known as munchausen syndrome, is related to munchausen by proxy and psychogenic movement, and has symptoms including nervousness An important gene associated with Factitious Disorder is APELA (Apelin Receptor Early Endogenous Ligand). Affiliated tissues include skin, brain and kidney, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 74 Factitious disorder imposed on self, also known as Munchausen syndrome, is a factitious disorder wherein... more...

Related Diseases for Factitious Disorder

Diseases related to Factitious Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 233)
# Related Disease Score Top Affiliating Genes
1 munchausen by proxy 32.8 APELA ALX3
2 psychogenic movement 11.2
3 personality disorder 10.4
4 somatization disorder 10.2
5 cystic fibrosis 10.2
6 diarrhea 10.2
7 borderline personality disorder 10.2
8 sudden infant death syndrome 10.1
9 seizure disorder 10.1
10 neuropathy, hereditary sensory and autonomic, type viii 10.1 PRDM12 APELA
11 physical disorder 10.1
12 conversion disorder 10.1
13 substance abuse 10.1
14 corpus callosum lipoma 10.1 APELA ALX3
15 cerebral hemisphere lipoma 10.1 APELA ALX3
16 pheochromocytoma 10.1
17 deficiency anemia 10.1
18 adrenal gland pheochromocytoma 10.1
19 aortic dissection 10.1
20 iron deficiency anemia 10.1
21 epilepsy 10.1
22 hyperinsulinism 10.1
23 iron metabolism disease 10.1
24 adult syndrome 10.0 INS APELA
25 reflex sympathetic dystrophy 10.0
26 major affective disorder 8 10.0
27 major affective disorder 9 10.0
28 dysthymic disorder 10.0
29 algoneurodystrophy 10.0
30 avoidant personality disorder 10.0
31 bipolar disorder 10.0
32 somatoform disorder 10.0
33 movement disease 10.0
34 septic arthritis 10.0
35 ocular motor apraxia 10.0
36 asthma 10.0
37 alexithymia 10.0
38 monocular esotropia 10.0
39 esophagitis 10.0
40 sleep disorder 10.0
41 vasculitis 10.0
42 otitis externa 10.0
43 esotropia 10.0
44 mycobacterium fortuitum 10.0
45 back pain 10.0
46 fibrosis of extraocular muscles, congenital, 1 10.0
47 otitis media 10.0
48 triiodothyronine receptor auxiliary protein 10.0
49 anemia, x-linked, with or without neutropenia and/or platelet abnormalities 10.0
50 congenital hemidysplasia with ichthyosiform erythroderma and limb defects 10.0

Graphical network of the top 20 diseases related to Factitious Disorder:



Diseases related to Factitious Disorder

Symptoms & Phenotypes for Factitious Disorder

UMLS symptoms related to Factitious Disorder:


nervousness

GenomeRNAi Phenotypes related to Factitious Disorder according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-100 9.44 TPSD1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-122 9.44 TPSD1
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-130 9.44 CPA4
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-166 9.44 PARP14
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-168 9.44 TPSD1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-171 9.44 PARP14
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-202 9.44 TPSD1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-24 9.44 CPA4
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-25 9.44 CPA4
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-26 9.44 PARP14
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-73 9.44 TPSD1
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.44 PARP14
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.44 TPSD1

Drugs & Therapeutics for Factitious Disorder

Search Clinical Trials , NIH Clinical Center for Factitious Disorder

Genetic Tests for Factitious Disorder

Anatomical Context for Factitious Disorder

MalaCards organs/tissues related to Factitious Disorder:

40
Skin, Brain, Kidney, Eye, Testes, Breast, Spinal Cord

Publications for Factitious Disorder

Articles related to Factitious Disorder:

(show top 50) (show all 1036)
# Title Authors PMID Year
1
Incidence of the diagnosis of factitious disorders - Nationwide comparison study between Germany and Norway. 61
32524413 2020
2
Factitious disorder commonly presents as dermatitis factitia: A U.S. population-based study. 61
32081412 2020
3
Suicidality in Factitious Disorder. 61
32441497 2020
4
An adolescent girl with signs and symptoms of anaphylaxis and negative immunologic workup: a case report. 61
32299506 2020
5
The other face of illness-deception: Diagnostic criteria for factitious disorder with proposed standards for clinical practice and research. 61
31535601 2020
6
Munchausen Syndrome. 61
32239233 2020
7
Overlooking Feigning Behavior May Result in Potential Harmful Treatment Interventions: Two Case Reports of Undetected Malingering. 61
32202670 2020
8
Migration of a foreign object to the parapharyngeal space: an unusual factitious disorder. 61
27381878 2020
9
[Hypoglycaemia and seizures in a 32-year-old woman with maple syrup urine disease]. 61
31996976 2020
10
Psychological Treatment of Factitious Disorder Imposed on Another/Munchausen by Proxy Abuse. 61
31089919 2020
11
Identification of chloramphenicol in human hair leading to a diagnosis of factitious disorder. 61
31913719 2020
12
Challenges Associated With Vascular Access Needs of Patients With Factitious Disorder. 61
31876773 2020
13
Clinical, demographic, psychological, and behavioral features of factitious disorder: A retrospective analysis. 61
30777298 2020
14
A case report of Munchausen syndrome presenting with bleeding from ear: a rare factitious disorder. 61
31954046 2020
15
The clenched fist syndrome: case report of a clinical rarity of special interest for psychiatrists and hand surgeons. 61
31703662 2019
16
Evaluation and Management of Factitious Disorder Imposed on Another. 61
31612305 2019
17
Medical Child Abuse Hidden in Pediatric Settings: Detection and Intervention. 61
31602528 2019
18
Dopamine dysregulation syndrome in non-Parkinson's disease patients: a systematic review. 61
31032624 2019
19
Differentiating Psychosomatic, Somatopsychic, Multisystem Illnesses, and Medical Uncertainty. 61
31597359 2019
20
Munchausen Syndrome: Self-Inflicted Chronic Scalp Injury and Hints for Surgeons. 61
31577567 2019
21
Munchausen syndrome mimicking refractory subcutaneous abscess with bacteremia, diagnosed by repetitive element sequence-based polymerase chain reaction: a case report. 61
31511062 2019
22
Ventricular tachycardia and chest pain due to foreign body in the pericardium caused by self-injurious behaviour. 61
31378212 2019
23
Dying to be Ill: Munchausen meets warfarin overdose. 61
31548969 2019
24
Early death in Munchausen syndrome: A case report. 61
31428370 2019
25
Unexplained destructive nasal lesions in half-brothers: A possible case of Munchausen syndrome by proxy. 61
31077906 2019
26
Fabricated or induced illness in twins associated with insertion of trocar needles into their bodies. 61
29882486 2019
27
Munchausen Syndrome by Proxy. 61
31334086 2019
28
Problems With Factitious Disorder, Malingering, and Somatic Symptoms in DSM-5. 61
30527844 2019
29
Severe hypokalemia secondary to abuse of β-adrenergic agonists in a pediatric patient: Case report. 61
31173041 2019
30
Breast surgeons dealing with Munchausen syndrome: A self-induced necrotic phlegmon of the breast treated with surgery, negative pressure and epidermal fractional skin grafting. 61
30980584 2019
31
Self-induced dermatoses: A great imitator. 61
31178108 2019
32
Factitial panniculitis as a manifestation of self-imposed factitious disorder. 61
31220899 2019
33
Triparesis: an unusual presentation of factitious disorder. 61
31076490 2019
34
Malingering and factitious disorder. 61
30425128 2019
35
Factitious Disorder and the Interdisciplinary Team: identification of signs and risk factors. 61
30810614 2019
36
Approach to diagnosis of factitious disorder with unexplained hemoptysis: A case report. 61
30732130 2019
37
Health providers induced iatrogenic delusions of infestation. 61
31564948 2019
38
The Incidence of Diagnosis of Munchausen Syndrome, Other Factitious Disorders, and Malingering. 61
30944662 2019
39
Repeated Enterocutaneous Fistula in a Munchausen Syndrome Patient. 61
31123443 2019
40
Dermatitis artefacta: self-inflicted genital injury. 61
30936755 2019
41
Fabricated facial rash - an unusual presentation of factitious disorder. 61
30573903 2018
42
Current Management of Self-Inflicted Wounds in Surgery: A Critical Review. 61
30383582 2018
43
Hypoglycemia secondary to factitious hyperinsulinism in a foster care adolescent - a case report of munchausen syndrome in a community hospital emergency department setting. 61
30537938 2018
44
Cutaneous Munchausen Syndrome by Proxy: A Diagnostic Challenge for Dermatologist. 61
30505786 2018
45
Ocular Munchausen's Syndrome induced by introduction of ant's particles into the conjunctival fornices. 61
30581311 2018
46
SELF-INFLICTED LASER HANDHELD LASER-INDUCED MACULOPATHY: A NOVEL OCULAR MANIFESTATION OF FACTITIOUS DISORDER. 61
28937524 2018
47
An Overview of Munchausen Syndrome and Munchausen Syndrome by Proxy. 61
30100003 2018
48
Religious stigmata: a dermato-psychiatric approach and differential diagnosis. 61
29624652 2018
49
A 90-year-old man with factious disorder: Separating fact from fiction. 61
29264941 2018
50
Histopathological patterns in dermatitis artefacta. 61
29689138 2018

Variations for Factitious Disorder

Expression for Factitious Disorder

Search GEO for disease gene expression data for Factitious Disorder.

Pathways for Factitious Disorder

GO Terms for Factitious Disorder

Cellular components related to Factitious Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 TPSD1 THEM6 INS CPA4 CPA3 APELA

Molecular functions related to Factitious Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carboxypeptidase activity GO:0004180 8.96 CPA4 CPA3
2 metallocarboxypeptidase activity GO:0004181 8.62 CPA4 CPA3

Sources for Factitious Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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