MCID: FCT008
MIFTS: 39

Factitious Disorder

Categories: Mental diseases
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Aliases & Classifications for Factitious Disorder

MalaCards integrated aliases for Factitious Disorder:

Name: Factitious Disorder 11 14 75
Factitious Disorders 71 33
Munchausen Syndrome 11 71
Münchausen Syndrome 75

Classifications:



External Ids:

Disease Ontology 11 DOID:1766
ICD9CM 34 300.16
SNOMED-CT 68 430751001
UMLS 71 C0015480 C0015481 C0026785

Summaries for Factitious Disorder

Disease Ontology: 11 A disease of mental health where symptoms are deliberately produced, feigned or exaggerated in order to falsely demonstrate the presence of an illness.

MalaCards based summary: Factitious Disorder, also known as factitious disorders, is related to munchausen by proxy and neurotic disorder, and has symptoms including nervousness An important gene associated with Factitious Disorder is INS (Insulin), and among its related pathways/superpathways are Metabolism and Integration of energy metabolism. Affiliated tissues include skin, spinal cord and kidney, and related phenotypes are homeostasis/metabolism and growth/size/body region

Wikipedia 75 Factitious disorder: A factitious disorder is a condition in which a person, without a malingering motive, acts as if they... more...

Münchausen syndrome: Factitious disorder imposed on self, also known as Munchausen syndrome, is a factitious disorder in... more...

Related Diseases for Factitious Disorder

Diseases related to Factitious Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 355)
# Related Disease Score Top Affiliating Genes
1 munchausen by proxy 31.7 KCNJ11 GCK ABCC8
2 neurotic disorder 30.3 POMC INS
3 graves disease 1 30.3 POMC INS
4 dysthymic disorder 30.1 POMC INS
5 hyperinsulinemic hypoglycemia, familial, 2 30.0 KCNJ11 INS ABCC8
6 substance abuse 29.9 POMC INS F2
7 hyperinsulinemic hypoglycemia, familial, 3 29.9 GCK ABCC8
8 hyperinsulinemic hypoglycemia, familial, 1 29.8 KCNJ11 ABCC8
9 hypoglycemic coma 29.8 POMC INS GCG
10 cellulitis 29.8 INS F2
11 urinary tract infection 29.7 INS GCG F2
12 anorexia nervosa 29.7 POMC INS GCG
13 necrotizing fasciitis 29.7 INS F2
14 diabetes mellitus, ketosis-prone 29.7 KCNJ11 INS GCG
15 alcohol use disorder 29.5 POMC INS F2
16 hyperthyroidism 29.5 POMC INS F2
17 hyperinsulinism 29.4 KCNJ11 INS GCK GCG ABCC8
18 insulinoma 29.0 KCNJ11 INS GCK GCG ABCC8
19 maturity-onset diabetes of the young 29.0 KCNJ11 INS GCK GCG ABCC8
20 hypoglycemia 29.0 POMC KCNJ11 INS GCK GCG ABCC8
21 hyperglycemia 29.0 KCNJ11 INS GCK GCG ABCC8
22 hyperinsulinemic hypoglycemia 29.0 POMC KCNJ11 INS GCK GCG ABCC8
23 personality disorder 10.4
24 acidophil adenoma 10.3 POMC INS
25 scleredema adultorum 10.3 POMC INS
26 pituitary infarct 10.3 POMC INS
27 central pontine myelinolysis 10.2 POMC INS
28 sheehan syndrome 10.2 POMC INS
29 hypothalamic disease 10.2 POMC INS
30 autoimmune polyendocrine syndrome, type ii 10.2 POMC INS
31 pituitary apoplexy 10.2 POMC INS
32 somatization disorder 10.2
33 psychotic disorder 10.2
34 myxedema 10.2 POMC INS
35 empty sella syndrome 10.2 POMC INS
36 steroid inherited metabolic disorder 10.2 POMC INS
37 fanconi-bickel syndrome 10.2 INS ABCC8
38 adrenal cortical hypofunction 10.2 POMC INS
39 type 1 diabetes mellitus 12 10.2 KCNJ11 INS
40 alcoholic ketoacidosis 10.2 INS GCG
41 conversion disorder 10.2
42 neurotic excoriation 10.2
43 postgastrectomy syndrome 10.2 INS GCG
44 balanitis 10.2 INS GCG
45 type 1 diabetes mellitus 15 10.1 INS GCG
46 nephrolithiasis, calcium oxalate 10.1
47 sudden infant death syndrome 10.1
48 congenital hemidysplasia with ichthyosiform erythroderma and limb defects 10.1
49 deficiency anemia 10.1
50 persistent fetal circulation syndrome 10.1 POMC INS

Graphical network of the top 20 diseases related to Factitious Disorder:



Diseases related to Factitious Disorder

Symptoms & Phenotypes for Factitious Disorder

UMLS symptoms related to Factitious Disorder:


nervousness

MGI Mouse Phenotypes related to Factitious Disorder:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.02 ABCC8 CPA3 F2 GCG GCK INS
2 growth/size/body region MP:0005378 9.96 ABCC8 CPA3 F2 GCG GCK INS
3 endocrine/exocrine gland MP:0005379 9.76 ABCC8 CPA3 F2 GCG GCK INS
4 cardiovascular system MP:0005385 9.56 ABCC8 F2 GCK INS KCNJ11 POMC
5 mortality/aging MP:0010768 9.32 CPA3 F2 GCG GCK INS KCNJ11

Drugs & Therapeutics for Factitious Disorder

Search Clinical Trials, NIH Clinical Center for Factitious Disorder

Genetic Tests for Factitious Disorder

Anatomical Context for Factitious Disorder

Organs/tissues related to Factitious Disorder:

MalaCards : Skin, Spinal Cord, Kidney, Brain, Eye, Breast, Tongue

Publications for Factitious Disorder

Articles related to Factitious Disorder:

(show top 50) (show all 1224)
# Title Authors PMID Year
1
Challenges to the Diagnosis of Functional Neurological Disorder: Feigning, Intentionality, and Responsibility. 62
36311548 2023
2
Munchausen syndrome with factitious hypoglycemia due to deliberate insulin analog administration and factitious hyperglycemia in a patient with hypothyroidism. 62
36376919 2022
3
Preserving Immunity for Reporters of Medical Child Abuse. 62
36223940 2022
4
Self-inflicted pathological cutaneous disorders. Part I. 62
36062949 2022
5
When a Histologic Diagnosis Becomes Factitious: A Case of Munchausen Syndrome. 62
36225520 2022
6
Self-inflicted pathological cutaneous disorders. Part two. 62
36177780 2022
7
"Extensive necrosis following extravasation of alkali in the crease of the elbow after voluntary intravenous injection: A case report". 62
35902288 2022
8
Difficult diagnosis of factitious disorder. 62
35787502 2022
9
A Fatal Case of Factitious Aplastic Anemia. 62
35797692 2022
10
Commentary: Futility in Psychiatry. 62
35797694 2022
11
Factitious Disorder: An Angioedema Copycat. 62
35795523 2022
12
Hypoglycemia and Factitious Disorders: A Case Report and Review. 62
35898373 2022
13
Organophosphate insecticide poisoning with monocrotophos-induced fabricated illness in a 7-year-old girl with refractory seizures over a 4-year period. 62
35938355 2022
14
"Non-healing Wounds": Addressing Complex Physical and Emotional Trauma in a Case of Factitious Disorder. 62
35421012 2022
15
[Suspected factitious disorder: identifying self-inflicted wounds in plastic surgery]. 62
35419782 2022
16
Is Auditory Steady-State Response Testing the Key for Diagnosing Non-Organic Hearing Disorders? Implications for Current Audiological Practice. 62
34922420 2022
17
The tic in TikTok and (where) all systems go: Mass social media induced illness and Munchausen's by internet as explanatory models for social media associated abnormal illness behavior. 62
35473358 2022
18
68 Ga-DOTATATE PET/CT imaging in endogenous hyperinsulinemic hypoglycemia: A tertiary endocrine centre experience. 62
34498757 2022
19
Ganser syndrome - a dissociative disorder or a factitious disorder? A case report. 62
35569148 2022
20
Munchausen syndrome by proxy (MSBP): a review regarding perpetrators of factitious disorder imposed on another (FDIA). 62
32772954 2022
21
Gaslighting in alleged assault ascertained as Munchausen syndrome transcending to malingering in highly counterintuitive self inflicted acid burns. 62
34654642 2022
22
A broader perspective: Functional symptoms beyond Neurology. 62
35198949 2022
23
Fabricated Diabetes Mellitus: A Rare Presentation of Munchausen Syndrome by Proxy. 62
34661858 2022
24
Secretan Syndrome: A Fluctuating Case of Factitious Lymphedema. 62
35167799 2021
25
["Somatic symptom disorders" in adolescence. A systematic review of the recent literature]. 62
34538623 2021
26
A descriptive, retrospective case series of patients with factitious disorder imposed on self. 62
34814866 2021
27
Factitious Gastrointestinal Bleeding: A Case Series and Review. 62
34551859 2021
28
The factitious/malingering continuum and its burden on public health costs: a review and experience in an Italian neurology setting. 62
34346017 2021
29
Factitious disorder of a 17-year-old female during COVID-19 pandemic. 62
33527607 2021
30
Factitious disorders in Germany-a detailed insight. 62
34213703 2021
31
Attempted Murder of a Young Child Followed by an Attempted Suicide of the Mother by Injection of Insulin Aspart: Identification of Quantification of Insulin by LC-HRMS and UPLC-MS/MS in Blood of the Two Cases. 62
34529061 2021
32
Psychiatric and legal considerations in cases of Fetal Abduction by Maternal Evisceration. 62
34156091 2021
33
Transitioning to chronic temporomandibular disorder pain: A combination of patient vulnerabilities and iatrogenesis. 62
33966303 2021
34
[Munchausen syndrome in a child]. 62
34344125 2021
35
Laser-Induced Maculopathy Masquerading as Hereditary Macular Dystrophy. 62
35125803 2021
36
Factitious disorder, presenting haemolacria in a Pakistani tribal illiterate female: A rare case report. 62
33241853 2021
37
The girl who cried wolf: A literature review and case report of pediatric factitious disorder. 62
33624517 2021
38
Wiping Away Cellulitis: A Case of Factitious Disorder. 62
34314328 2021
39
BARONESS CHARLOTTA CASTELLI GLEMBAY - WAS SHE HYPERSEXUAL? 62
35212207 2021
40
Pediatric Factitious Disorder Perpetuated by Others: A Dermatologist's Duty Beyond the Skin. 62
34188745 2021
41
Munchausen by internet and false perinatal crises. 62
33878290 2021
42
Factitious Disorder (Munchausen Syndrome) in Plastic Surgery: A Systematic Review of 42 Cases. 62
32804718 2021
43
Factitious Disorder in Seven Patients: A Saudi Experience. 62
33927938 2021
44
Munchausen syndrome: report of a case and implications for dentists. 62
33661116 2021
45
Evaluation and Management of Factitious Disorder Imposed on Another. 62
31612305 2021
46
Interdisciplinarity and Integration: An Introduction to the Special Issue on Psychopathology in Medical Settings. 62
33219478 2021
47
Loss of Consciousness in the Young Child. 62
33388850 2021
48
Striving to Die: Medical, Legal, and Ethical Dilemmas Behind Factitious Disorder. 62
33585147 2021
49
A brain origin for factitious disorder (Munchausen's) with malingering? A single case with an old frontal lobe lesion. 62
33306455 2021
50
[To pretend or to really suffer ? Questions from caregivers about the factitious disorder]. 62
33586374 2021

Variations for Factitious Disorder

Expression for Factitious Disorder

Search GEO for disease gene expression data for Factitious Disorder.

Pathways for Factitious Disorder

Pathways related to Factitious Disorder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.32 VKORC1 POMC KCNJ11 INS GCK GCG
2
Show member pathways
12.02 KCNJ11 INS GCG ABCC8
3
Show member pathways
11.71 POMC INS GCK
4
Show member pathways
11.69 POMC INS GCG CPA3
5 11.02 INS GCG
6
Show member pathways
10.95 VKORC1 F2
7 10.71 POMC INS
8 10.7 KCNJ11 INS GCK ABCC8
9
Show member pathways
10.65 KCNJ11 INS GCK F2 ABCC8

GO Terms for Factitious Disorder

Cellular components related to Factitious Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule lumen GO:0034774 9.43 POMC INS GCG
2 inward rectifying potassium channel GO:0008282 8.92 KCNJ11 ABCC8

Biological processes related to Factitious Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of proteolysis GO:0045861 9.73 INS F2
2 glucose metabolic process GO:0006006 9.73 KCNJ11 INS GCK
3 negative regulation of gluconeogenesis GO:0045721 9.71 INS GCK
4 positive regulation of glycogen biosynthetic process GO:0045725 9.67 INS GCK
5 regulation of insulin secretion GO:0050796 9.63 KCNJ11 GCK GCG
6 regulation of blood coagulation GO:0030193 9.62 VKORC1 F2
7 positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 9.26 KCNJ11 GCG ABCC8
8 glucose homeostasis GO:0042593 9.23 POMC INS GCK GCG

Molecular functions related to Factitious Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase-coupled monoatomic cation transmembrane transporter activity GO:0019829 9.46 KCNJ11 ABCC8
2 hormone activity GO:0005179 9.43 POMC INS GCG
3 ATP-activated inward rectifier potassium channel activity GO:0015272 8.92 KCNJ11 ABCC8

Sources for Factitious Disorder

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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