Aliases & Classifications for Fainting

MalaCards integrated aliases for Fainting:

Name: Fainting 53 42

Summaries for Fainting

NINDS : 53 Syncope is a medical term used to describe a temporary loss of consciousness due to the sudden decline of blood flow to the brain. Syncope is commonly called fainting or “passing out.” If an individual is about to faint, he or she will feel dizzy, lightheaded, or nauseous and their field of vision may “white out” or “black out.”  The skin may be cold and clammy.  The person drops to the floor as he or she loses consciousness.  After fainting, an individual may be unconscious for a minute or two, but will revive and slowly return to normal.  Syncope can occur in otherwise healthy people and affects all age groups, but occurs more often in the elderly.  There are several types of syncope.  Vasovagal syncope usually has an easily identified triggering event such as emotional stress, trauma, pain, the sight of blood, or prolonged standing.  Carotid sinus syncope happens because of constriction of the carotid artery in the neck and can occur after turning the head, while shaving, or when wearing a tight collar.  Situational syncope happens during urination, defecation, coughing, or as a result of gastrointestinal stimulation.  Syncope can also be a symptom of heart disease or abnormalities that create an uneven heart rate or rhythm that temporarily affect blood volume and its distribution in the body.  Syncope isn’t normally a primary sign of a neurological disorder, but it may indicate an increased risk for neurologic disorders such as Parkinson’s disease, postural orthostatic tachycardia syndrome (POTS), diabetic neuropathy, and other types of neuropathy.  Certain classes of drugs are associated with an increased risk of syncope, including diuretics, calcium antagonists, ACE inhibitors, nitrates, antipsychotics, antihistamines, levodopa, narcotics, and alcohol.

MalaCards based summary : Fainting is related to pediatric angiosarcoma and breast hemangioma. An important gene associated with Fainting is F8 (Coagulation Factor VIII), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Sodium citrate and Lactulose have been mentioned in the context of this disorder. Affiliated tissues include heart, whole blood and pancreas.

MedlinePlus : 42 Fainting is a temporary loss of consciousness. If you're about to faint, you'll feel dizzy, lightheaded, or nauseous. Your field of vision may "white out" or "black out." Your skin may be cold and clammy. You lose muscle control at the same time, and may fall down. Fainting usually happens when your blood pressure drops suddenly, causing a decrease in blood flow to your brain. It is more common in older people. Some causes of fainting include Heat or dehydration Emotional distress Standing up too quickly Certain medicines Drop in blood sugar Heart problems When someone faints, make sure that the airway is clear and check for breathing. The person should stay lying down for 10-15 minutes. Most people recover completely. Fainting is usually nothing to worry about, but it can sometimes be a sign of a serious problem. If you faint, it's important to see your health care provider and find out why it happened.

Wikipedia : 73 Syncope, also known as fainting, is a loss of consciousness and muscle strength characterized by a fast... more...

Related Diseases for Fainting

Diseases related to Fainting via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
# Related Disease Score Top Affiliating Genes
1 pediatric angiosarcoma 10.0 VWF F8
2 breast hemangioma 10.0 VWF F8
3 thyroid angiosarcoma 10.0 VWF F8
4 lymphangiosarcoma 10.0 VWF F8
5 acquired von willebrand syndrome 10.0 VWF F8
6 von willebrand disease, type 2 10.0 VWF F8
7 von willebrand disease, type 3 10.0 VWF F8
8 hemarthrosis 10.0 VWF F8
9 angiodysplasia 10.0 VWF F8
10 von willebrand disease, type 1 10.0 VWF F8
11 brachydactyly, type d 10.0 VWF F8
12 intracranial thrombosis 10.0 VWF F8
13 thrombosis 10.0 VWF F8
14 thrombophlebitis 10.0 VWF F8
15 factor v deficiency 10.0 VWF F8
16 central retinal vein occlusion 10.0 VWF F8
17 factor xiii deficiency 10.0 VWF F8
18 thrombophilia due to activated protein c resistance 10.0 VWF F8
19 thrombophilia 10.0 VWF F8
20 pulmonary artery disease 10.0 VWF F8
21 hemophilia a 10.0 VWF F8
22 factor xi deficiency 10.0 VWF F8
23 vein disease 10.0 VWF F8
24 von willebrand's disease 10.0 VWF F8
25 factor viii deficiency 10.0 VWF F8
26 thrombophilia due to thrombin defect 9.9 VWF F8
27 afibrinogenemia, congenital 9.9 VWF F8
28 glanzmann thrombasthenia 9.9 VWF F8
29 pulmonary embolism 9.9 VWF F8
30 factor vii deficiency 9.9 HNF4A F8
31 bernard-soulier syndrome 9.9 VWF F8
32 x-linked recessive disease 9.9 VWF F8
33 blood platelet disease 9.9 VWF F8
34 blood coagulation disease 9.9 VWF F8
35 cerebrovascular disease 9.7 VWF F8
36 hemophilia b 9.7 VWF HNF4A F8
37 atrial fibrillation 9.7 VWF KCNH2
38 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 9.6 KCNH2 HNF4A
39 heart conduction disease 9.6 VWF KCNH2
40 hemorrhagic disease 9.6 VWF F8

Graphical network of the top 20 diseases related to Fainting:

Diseases related to Fainting

Symptoms & Phenotypes for Fainting

Drugs & Therapeutics for Fainting

Drugs for Fainting (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 58)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Sodium citrate Approved, Investigational Phase 3 68-04-2
Lactulose Approved Phase 3 4618-18-2 11333
Norepinephrine Approved Phase 3 51-41-2 439260
Pancrelipase Approved, Investigational Phase 3 53608-75-6
Irinotecan Approved, Investigational Phase 3 100286-90-6, 97682-44-5 60838
Gemcitabine Approved Phase 3 95058-81-4 60750
Fluorouracil Approved Phase 3 51-21-8 3385
Levoleucovorin Approved, Investigational Phase 3 68538-85-2 149436
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 5310940 9887054 43805 6857599
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
leucovorin Approved Phase 3 58-05-9 6006
Citric acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
14 Acidophilus Phase 3
15 Citrate Phase 3
16 Immunosuppressive Agents Phase 3
17 Immunologic Factors Phase 3
18 Pharmaceutical Solutions Phase 3
19 Trace Elements Phase 3
20 Nutrients Phase 3
21 Vitamins Phase 3
22 Micronutrients Phase 3
23 Vitamin B Complex Phase 3
24 Vitamin B9 Phase 3
25 Tubulin Modulators Phase 3
26 topoisomerase I inhibitors Phase 3
27 Antidotes Phase 3
28 pancreatin Phase 3
29 Antimitotic Agents Phase 3
30 Protective Agents Phase 3
31 Folate Phase 3
32 Albumin-Bound Paclitaxel Phase 3
33 Antiviral Agents Phase 3
34 Antimetabolites Phase 3
35 Anti-Infective Agents Phase 3
36 Calcium, Dietary Phase 3
Calcium Nutraceutical Phase 3 7440-70-2 271
Etanercept Approved, Investigational Phase 1, Phase 2 185243-69-0
39 Gastrointestinal Agents Phase 1, Phase 2
40 Analgesics, Non-Narcotic Phase 1, Phase 2
41 Analgesics Phase 1, Phase 2
42 Antirheumatic Agents Phase 1, Phase 2
43 Anti-Inflammatory Agents Phase 1, Phase 2
44 Anti-Inflammatory Agents, Non-Steroidal Phase 1, Phase 2
45 Autoantibodies Phase 1, Phase 2
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
Carbon monoxide Approved, Investigational 630-08-0 281
Ibuprofen Approved 15687-27-1 3672
Levobupivacaine Approved, Investigational 27262-47-1 92253
Vitamin D Approved, Nutraceutical, Vet_approved 1406-16-2

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 Syncope: Pacing or Recording in the Later Years (SPRITELY) Completed NCT01423994 Phase 4
2 Lactobacillus Reuteri in Treatment of Functional Abdominal Pain and Chronic Constipation in Children - Randomized, Double Blind, Placebo Controlled Study Unknown status NCT01587846 Phase 3
3 A Phase 3, 4-week, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of TD-9855 in Treating Symptomatic Neurogenic Orthostatic Hypotension in Subjects With Primary Autonomic Failure Recruiting NCT03750552 Phase 3 ampreloxetine;Placebo
4 A Phase 3, 22-week, Multi-center, Randomized Withdrawal Study of TD-9855 in Treating Symptomatic Neurogenic Orthostatic Hypotension in Subjects With Primary Autonomic Failure Recruiting NCT03829657 Phase 3 ampreloxetine;Placebo
5 A Phase 3, 182-week, Open-Label, Extension Study to Investigate the Safety and Tolerability of TD-9855 in Treating Symptomatic Neurogenic Orthostatic Hypotension (Symptomatic nOH) in Subjects With Primary Autonomic Failure Recruiting NCT04095793 Phase 3 ampreloxetine
6 An Open-label, Randomised, Multicentre, Phase III Study of Irinotecan Liposome Injection, Oxaliplatin, 5-fluorouracil/Leucovorin Versus Nab-paclitaxel Plus Gemcitabine in Subjects Who Have Not Previously Received Chemotherapy for Metastatic Adenocarcinoma of the Pancreas Recruiting NCT04083235 Phase 3 Irinotecan Liposomal Injection;Oxaliplatin;5Fluorouracil;Leucovorin;Nab-paclitaxel;Gemcitabine
7 ASIS for Enbrel in Plaque Psoriasis Unknown status NCT02112097 Phase 1, Phase 2 Gadolinium;Gadolinium;Gadolinium;Efficacy of Enbrel subcutaneously at Week 12;Efficacy of Enbrel subcutaneously at Week 24;Efficacy of Enbrel subcutaneously at Week 36;Efficacy of Enbrel subdermally at Week 12;Efficacy of Enbrel subdermally at Week 24;Efficacy of Enbrel subdermally at Week 36;PASI 75 n(%) subcutaneously at Week 12;PASI 75 n(%) subcutaneously at Week 24;PASI 75 n(%) subcutaneously at Week 36;PASI 75 n(%) subdermally at Week 12;PASI 75 n(%) subdermally at Week 24;PASI 75 n(%) subdermally at Week 36;Adverse Reactions of Enbrel subcutaneously;Adverse Reactions of Enbrel subdermally at Week 36;Gadolinium;Gadolinium;Gadolinium
8 Observational Study of the Sleuth Implantable ECG Monitoring System Unknown status NCT00717106
9 CNS Targets of Propofol's Hypnotic and Memory Effects Completed NCT00576615 Placebo solution;propofol
10 Evaluation of the Efficiency of a Hydration by Isotonic Solution With or Without Muscular Exercise of the Fainting Whole Blood Donors Completed NCT02075099
11 Interaction Effects of Vitamin D Supplementation and Aerobic Exercises on Balance and Physical Performance in Children With Down Syndrome Completed NCT03783338
12 Ten-year Trends in the Pre-hospital Emergency Care Spectrum in Beijing From 2005 to 2014: A Multicenter, Retrospective, Observational Study Completed NCT02645877
13 A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease Completed NCT01182532 TCM Syndrome Differentiation and Treatment
14 Comparison of Effectiveness of Ultrasound Guided Erector Spinae Plane Block With Ultrasound Guided Serratus Anterior Block in Modified Radical Mastectomy, Randomized Single Blinded Comparative Study. Completed NCT04606147
15 Parkinson's Disease Genetics Database Terminated NCT00855556

Search NIH Clinical Center for Fainting

Genetic Tests for Fainting

Anatomical Context for Fainting

MalaCards organs/tissues related to Fainting:

Heart, Whole Blood, Pancreas, Spinal Cord, Endothelial, Eye, Spleen

Publications for Fainting

Articles related to Fainting:

(show top 50) (show all 1172)
# Title Authors PMID Year
Syncope at SARS-CoV-2 onset. 42
32977101 2020
Association Between US Physician Malpractice Claims Rates and Hospital Admission Rates Among Patients With Lower-Risk Syncope. 42
33320263 2020
Incorporating Latent Variables Using Nonnegative Matrix Factorization Improves Risk Stratification in Brugada Syndrome. 42
33170070 2020
The association between the biometeorological indicators and emergency interventions due to fainting: A retrospective cohort study. 61
33736408 2021
Clinical and echocardiographic outcomes after percutaneous closure of patent foramen ovale: a single centre experience. 61
33703865 2021
Research progress on the pharmacological effect and clinical application of Tongqiao Huoxue Decoction in the treatment of ischaemic stroke. 61
33711554 2021
Psychometric properties of the social interaction anxiety scale and the social phobia scale in Hungarian adults and adolescents. 61
33771109 2021
Safety in Dermatologic Procedures: Anaphylaxis, Vasovagal Reaction, and Hyperventilation. 61
33745892 2021
A qualitative study to identify factors that influence patients' decisions to call Emergency Medical Services for syncope. 61
33709359 2021
[Evaluation of measures to reduce the number of emergency physician missions in Tyrol during the COVID-19 pandemic]. 61
33569715 2021
Electronic Health Record-Based Prediction of 1-Year Risk of Incident Cardiac Dysrhythmia: Prospective Case-Finding Algorithm Development and Validation Study. 61
33595452 2021
Pathophysiology and symptoms of renal colic in children - A case report. 61
33743559 2021
A Case of Lafora Disease Diagnosed by Axillary Skin Biopsy. 61
33432562 2021
Risk of ambulance services associated with ambient temperature, fine particulate and its constituents. 61
33462328 2021
Awareness of Secondary School Students regarding Basic Life Support in Abha City, Southern Saudi Arabia: A Cross-Sectional Survey. 61
33603571 2021
Degree of Bystander-Patient Relationship and Prehospital Care for Opioid Overdose. 61
32073921 2021
Methods and Implementation of the 2019 EMS Practice Analysis. 61
33301370 2021
Managing pain and fear: Playing your CARDs to improve the vaccination experience. 61
33679251 2021
Multidetector computed tomography three-dimensional and multiplanar reconstruction diagnosis of a rare cause of gastrointestinal bleeding: A case report. 61
33552396 2021
An eight-camera fall detection system using human fall pattern recognition via machine learning by a low-cost android box. 61
33510202 2021
Predicting Vasovagal Responses: A Model-Based and Machine Learning Approach. 61
33776889 2021
Frontal Sinus Fractures: 10-Year Contemporary Experience at a Level 1 Urban Trauma Center. 61
33645957 2021
Donation related fears predict vasovagal reactions and donor attrition among high school donors. 61
32997822 2021
Are the health needs of children with disabilities being met at primary schools? 61
30621499 2020
Growing Skull Fracture of Temporal Bone in Adults: A Case Report and Literature Review. 61
32207331 2020
A randomised wait-list controlled pilot trial of one-session virtual reality exposure therapy for blood-injection-injury phobias. 61
32871696 2020
Ovarian ectopic pregnancy after in vitro fertilisation treated by laparoscopic excision with ovarian preservation. 61
33139361 2020
Profile of acupuncture use among primary care physicians working in the Brazilian public healthcare system. 61
32538101 2020
The effect of knowledge levels of individuals receiving basic first aid training in Turkey on the applications of first aid. 61
33047705 2020
Surgical management of hypertrophic obstructive cardiomyopathy. 61
32040818 2020
Enhancing predictions of patient conveyance using emergency call handler free text notes for unconscious and fainting incidents reported to the London Ambulance Service. 61
32663739 2020
It was not a fall, but fainting: A case report of pulmonary embolism. 61
32713871 2020
[Strategy research and analysis on 10 590 cases of invalid ambulance attendance in prehospital emergency care in Nanshan District of Shenzhen from 2014 to 2018]. 61
32912418 2020
National Estimates of hospital emergency department visits due to acute injuries associated with hookah smoking, United States, 2011-2019. 61
32772919 2020
Effect of "Tonifying Kidney and Invigorating Brain" acupuncture in children with spastic cerebral palsy analyzed by multi-modality MRI combined with dynamic electroencephalogram. 61
32791681 2020
Smart Supervision of Cardiomyopathy Based on Fuzzy Harris Hawks Optimizer and Wearable Sensing Data Optimization: A New Model. 61
32579536 2020
4th A in a triple A syndrome - A rare case report. 61
32589602 2020
Surviving monotony and repetitiveness at Hawthorne Works: the case of Geraldina “Jennie” Sirchio (1907-1992) and the other migrant girls in the test-room. 61
32624563 2020
Concealed congenital long QT syndrome during velopharyngeal dysfunction correction: a case report. 61
32617412 2020
Managing immunization stress-related response: A contributor to sustaining trust in vaccines. 61
32673376 2020
Case Report: Fainting During Acupuncture Treatment. 61
31719213 2020
Non-motor symptoms depending on motor severity in Japanese patients with Parkinson's disease: A multicenter cross-sectional study. 61
32151836 2020
[Dangerous practices and games at school]. 61
32877107 2020
First Trimester Uterine Rupture: A Case Report and Literature Review. 61
32344763 2020
Hookah venue employees' knowledge and perceptions of hookah tobacco smoking. 61
32300027 2020
A computational intelligence tool for the detection of hypertension using empirical mode decomposition. 61
32174317 2020
Occupational health and safety incidents at a university school of nursing: A retrospective, descriptive appraisal. 61
32244046 2020
HIV self-testing intervention experiences and kit usability: results from a qualitative study among men who have sex with men in the SELPHI (Self-Testing Public Health Intervention) randomized controlled trial in England and Wales. 61
31821698 2020
Deep Infiltrating Endometriosis and Spontaneous Hemoperitoneum: A Life-Threatening Situation Treated by Laparoscopy. 61
31376586 2020
Ambulance Services Associated with Extreme Temperatures and Fine Particles in a Subtropical Island. 61
32071336 2020

Variations for Fainting

Expression for Fainting

Search GEO for disease gene expression data for Fainting.

Pathways for Fainting

Pathways related to Fainting according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
Show member pathways
11.16 VWF F8
2 10.78 VWF F8

GO Terms for Fainting

Cellular components related to Fainting according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 8.62 VWF F8

Biological processes related to Fainting according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.32 VWF F8
2 platelet activation GO:0030168 9.26 VWF F8
3 hemostasis GO:0007599 9.16 VWF F8
4 blood coagulation, intrinsic pathway GO:0007597 8.96 VWF F8
5 blood coagulation GO:0007596 8.8 VWF HNF4A F8

Sources for Fainting

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
69 Tocris
71 UMLS via Orphanet
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