MCID: FLL023
MIFTS: 28

Fallopian Tube Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Fallopian Tube Adenocarcinoma

MalaCards integrated aliases for Fallopian Tube Adenocarcinoma:

Name: Fallopian Tube Adenocarcinoma 12 15 70
Adenocarcinoma of the Fallopian Tube 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3706
NCIt 50 C6265
UMLS 70 C1333590

Summaries for Fallopian Tube Adenocarcinoma

Disease Ontology : 12 A fallopian tube carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Fallopian Tube Adenocarcinoma, also known as adenocarcinoma of the fallopian tube, is related to papillary serous adenocarcinoma and ovarian cystadenocarcinoma. An important gene associated with Fallopian Tube Adenocarcinoma is ATP5IF1 (ATP Synthase Inhibitory Factor Subunit 1), and among its related pathways/superpathways is Antifolate resistance. The drugs Paclitaxel and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include endothelial, cervix and lymph node, and related phenotype is reproductive system.

Related Diseases for Fallopian Tube Adenocarcinoma

Graphical network of the top 20 diseases related to Fallopian Tube Adenocarcinoma:



Diseases related to Fallopian Tube Adenocarcinoma

Symptoms & Phenotypes for Fallopian Tube Adenocarcinoma

MGI Mouse Phenotypes related to Fallopian Tube Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 9.02 ATP5IF1 BRCA1 FOLR1 FZD3 IZUMO1R

Drugs & Therapeutics for Fallopian Tube Adenocarcinoma

Drugs for Fallopian Tube Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
2
Bevacizumab Approved, Investigational Phase 2 216974-75-3
3 Angiogenesis Inhibitors Phase 2
4 Tubulin Modulators Phase 2
5 Antineoplastic Agents, Immunological Phase 2
6 Immunoglobulins, Intravenous Phase 2
7 Antimitotic Agents Phase 2
8 Immunoglobulin G Phase 2
9 Mitogens Phase 2
10 Albumin-Bound Paclitaxel Phase 2
11 Endothelial Growth Factors Phase 2
12 Antibodies Phase 2
13 Immunoglobulins Phase 2
14 Immunologic Factors Phase 2
15 Antibodies, Monoclonal Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Phase II Induction Discontinuation Trial of Emactuzumab Following Paclitaxel and Bevacizumab in Patients With Platinum-Resistant, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Active, not recruiting NCT02923739 Phase 2 Paclitaxel
2 A Phase II Trial of Hu3S193 Consolidation Therapy for Patients With Relapsing Platinum-sensitive Ovarian, Primary Peritoneal and Fallopian Tubes Adenocarcinoma, Who Achieved a Second Complete Response Terminated NCT01137071 Phase 2
3 A Prospective, Longitudinal Study of YKL-40 in Patients With FIGO Stage III or IV Invasive Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancer Undergoing Primary Chemotherapy Terminated NCT00899093

Search NIH Clinical Center for Fallopian Tube Adenocarcinoma

Genetic Tests for Fallopian Tube Adenocarcinoma

Anatomical Context for Fallopian Tube Adenocarcinoma

MalaCards organs/tissues related to Fallopian Tube Adenocarcinoma:

40
Endothelial, Cervix, Lymph Node, Ovary

Publications for Fallopian Tube Adenocarcinoma

Articles related to Fallopian Tube Adenocarcinoma:

(show top 50) (show all 125)
# Title Authors PMID Year
1
Paraneoplastic cerebellar degeneration heralding recurrence of fallopian tube adenocarcinoma: A case report and literature review. 61
32904367 2020
2
Anterior mediastinal metastasis of primary fallopian tube adenocarcinoma: a case report. 61
32393292 2020
3
A Preliminary Report Requiring Continuation of Research to Confirm Fallopian Tube Adenocarcinoma: A Non-Experimental, Non-Randomized, Cross-Sectional Study. 61
30059956 2018
4
Primary Adenocarcinoma of the Fallopian Tube: A Rare Entity. 61
29207787 2017
5
Paraneoplastic cerebellar degeneration in a patient with a primary fallopian tube adenocarcinoma. A case report and brief review. 61
28386581 2017
6
[Expression of ATPase inhibitory factor 1 in normal and pathological tissues of female reproductive system]. 61
27998856 2016
7
Spinal Metastases from a Primary Fallopian Tube Serous Adenocarcinoma: A Case Report. 61
26430604 2015
8
Primary Fallopian Tube Clear Cell Adenocarcinoma in Pregnancy: Case Presentation and Review of the Literature. 61
26090245 2015
9
Preoperative diagnosis of fallopian tube malignancy with transvaginal color doppler ultrasonography and magnetic resonance imaging after negative hysteroscopy for postmenopausal bleeding. 61
25420393 2014
10
Primary serous papillary adenocarcinoma of the fallopian tube. 61
25163242 2014
11
Long-term disease-free survival in a patient with cerebral recurrence from adenocarcinoma of the fallopian tube. 61
23815803 2013
12
[Atypical debut of symptoms of fallopian tube cancer]. 61
24011209 2013
13
Proteomic analyses of serous and endometrioid epithelial ovarian cancers - cases studies - molecular insights of a possible histological etiology of serous ovarian cancer. 61
23589350 2013
14
Primary papillary adenocarcinoma of the fallopian tube with ovarian metastasis. 61
22923929 2012
15
Primary adenocarcinoma of the fallopian tube presenting as hydrosalpinx. 61
21627441 2011
16
Primary and bilateral tubal carcinoma is associated with long-standing granulomatous inflammation and primary infertility: a case report. 61
20666969 2010
17
[Primitive adenocarcinoma of the fallopian tube]. 61
20582893 2010
18
Bilateral microscopic adenocarcinoma of the fallopian tubes detected by an endometrial cytologic smear. 61
20407329 2010
19
Clinical characteristics and choices regarding risk-reducing surgery in BRCA mutation carriers. 61
20090358 2010
20
Challenging diagnosis: florid epithelial hyperplasia versus adenocarcinoma of the fallopian tube. 61
20025495 2010
21
Primary fallopian tube adenocarcinoma with brain and lung metastasis. 61
19805996 2009
22
Serous adenocarcinoma of the fallopian tube, associated with verrucous carcinoma of the uterine cervix: a case report of synchronic rare gynecological tumors. 61
19222847 2009
23
Primary transitional cell carcinoma of the fallopian tube in a premenopausal woman: A case report and review of literature. 61
20668606 2009
24
Fallopian tube carcinoma metastatic to the pericardium and breast. 61
19697636 2009
25
Primary adenocarcinoma of the fallopian tube as an incidental finding during surgery in a postmenopausal patient with unspecific pelvic pain. 61
19899428 2009
26
Occult malignancy in patients with suspected paraneoplastic neurologic syndromes: value of positron emission tomography in diagnosis. 61
18674476 2008
27
Primary bilateral tubal adenocarcinoma associated with uterine leiomyomas. 61
18417847 2008
28
Fallopian tube malignancies: A retrospective clinical pathological study of 17 cases. 61
18259909 2008
29
Synchronous granulosa cell tumour of the ovary and fallopian tube adenocarcinoma: two rare gynaecological malignancies. 61
17116067 2006
30
Sister Mary Joseph's nodule as the first presenting sign of primary fallopian tube adenocarcinoma. 61
16698532 2006
31
Paraneoplastic cerebellar degeneration with fallopian tube adenocarcinoma. 61
16126258 2005
32
Cerebral metastasis from a primary adenocarcinoma of the fallopian tube. 61
15385143 2004
33
[Unusual presentation of fallopian tube adenocarcinoma]. 61
15220848 2004
34
Superior vena cava syndrome during chemotherapy for stage 3c fallopian tube adenocarcinoma. 61
15047247 2004
35
[Primitive adenocarcinoma of the fallopian tube: a case report]. 61
15185603 2004
36
Primary adenocarcinoma of the fallopian tube: a case report. 61
15597861 2004
37
Primary fallopian tube adenocarcinoma: preoperative diagnosis, treatment and follow-up. 61
15493187 2004
38
Management of advanced-stage primary carcinoma of the fallopian tube: case report and literature review. 61
14658603 2003
39
[Clinical case of the month. Constipation and abdominal mass syndrome in a 51-year-old patient]. 61
12564098 2002
40
Hydrotubation for diagnosing carcinoma in situ of the fallopian tube. A case report. 61
12146042 2002
41
[Fallopian tube adenocarcinoma: synchronous neoplasia and severe uterine endocervical squamous epithelial dysplasia]. 61
11785120 2001
42
[Association of fallopian tube cancer and polymyositis. Apropos of 1 case]. 61
11883028 2001
43
Cough in a patient with an infusion port. 61
11555547 2001
44
Inguinal lymph node metastasis: an unusual presentation of fallopian tube carcinoma. 61
11330971 2001
45
Primary peritoneal malignant mixed Müllerian tumors. A clinicopathologic, immunohistochemical, and genetic study. 61
11251959 2001
46
Paraneoplastic cerebellar degeneration heralding fallopian tube adenocarcinoma. 61
11328418 2001
47
Phase II study of a combination of cyclophosphamide, adriamycin and cisplatin in advanced fallopian tube carcinoma. An EORTC gynecological cancer group study. European Organization for Research and Treatment of Cancer. 61
11501769 2001
48
Overexpression of p53 and HER-2/neu and c-myc in primary fallopian tube carcinoma. 61
10629373 2000
49
Outcome of advanced primary fallopian tube adenocarcinoma. 61
10575806 1999
50
A case of endometrioid carcinoma of the fallopian tube mimicking an adnexal tumor of probable Wolffian origin. 61
10379682 1999

Variations for Fallopian Tube Adenocarcinoma

Expression for Fallopian Tube Adenocarcinoma

Search GEO for disease gene expression data for Fallopian Tube Adenocarcinoma.

Pathways for Fallopian Tube Adenocarcinoma

Pathways related to Fallopian Tube Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.11 IZUMO1R FOLR1

GO Terms for Fallopian Tube Adenocarcinoma

Cellular components related to Fallopian Tube Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.13 FZD3 FOLR1 ATP5IF1
2 anchored component of external side of plasma membrane GO:0031362 8.62 IZUMO1R FOLR1

Biological processes related to Fallopian Tube Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fusion of sperm to egg plasma membrane involved in single fertilization GO:0007342 8.96 IZUMO1R FOLR1
2 sperm-egg recognition GO:0035036 8.62 IZUMO1R FOLR1

Molecular functions related to Fallopian Tube Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 folic acid binding GO:0005542 8.62 IZUMO1R FOLR1

Sources for Fallopian Tube Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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