MCID: FLL028
MIFTS: 22

Fallopian Tube Carcinosarcoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Fallopian Tube Carcinosarcoma

MalaCards integrated aliases for Fallopian Tube Carcinosarcoma:

Name: Fallopian Tube Carcinosarcoma 12 15 73
Fallopian Tube Malignant Mixed Mesodermal Tumor 12
Fallopian Tube Malignant Mixed Mullerian Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1970
NCIt 50 C40124
UMLS 73 C1517117

Summaries for Fallopian Tube Carcinosarcoma

Disease Ontology : 12 A fallopian tube cancer that is characterized as a mixture of carcinoma and sarcoma and has material basis in epithelial tissue and has material basis in connective tissue.

MalaCards based summary : Fallopian Tube Carcinosarcoma, also known as fallopian tube malignant mixed mesodermal tumor, is related to peritoneal benign neoplasm and diffuse peritoneal leiomyomatosis. An important gene associated with Fallopian Tube Carcinosarcoma is WT1 (Wilms Tumor 1), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Carboplatin and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include endothelial, ovary and testis.

Related Diseases for Fallopian Tube Carcinosarcoma

Diseases related to Fallopian Tube Carcinosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
# Related Disease Score Top Affiliating Genes
1 peritoneal benign neoplasm 10.0 CALB2 WT1
2 diffuse peritoneal leiomyomatosis 10.0 CALB2 WT1
3 venous hemangioma 10.0 CALB2 WT1
4 malignant biphasic mesothelioma 10.0 CALB2 WT1
5 adenomatoid tumor 10.0 CALB2 WT1
6 mixed germ cell-sex cord neoplasm 10.0 CALB2 WT1
7 spindle cell liposarcoma 10.0 CALB2 WT1
8 sertoli cell tumor 10.0 CALB2 WT1
9 sertoli-leydig cell tumor 10.0 CALB2 WT1
10 pneumatosis cystoides intestinalis 10.0 CALB2 WT1
11 pleural cancer 10.0 CALB2 WT1
12 dysgerminoma of ovary 10.0 CALB2 WT1
13 ovarian brenner tumor 9.9 CALB2 WT1
14 ovarian serous adenofibroma 9.9 CALB2 NCAM1
15 sex cord-gonadal stromal tumor 9.9 CALB2 WT1
16 rete testis adenoma 9.9 CALB2 NCAM1
17 ovarian serous cystadenofibroma 9.9 CALB2 NCAM1
18 cystadenofibroma 9.9 CALB2 NCAM1
19 malignant pleural mesothelioma 9.9 CALB2 WT1
20 mesothelioma, malignant 9.9 CALB2 WT1
21 spermatocele 9.9 CALB2 NCAM1
22 rete testis neoplasm 9.9 CALB2 NCAM1
23 wilms tumor 1 9.9 CALB2 WT1
24 renal adenoma 9.9 NCAM1 WT1
25 epithelial predominant wilms' tumor 9.9 NCAM1 WT1
26 mixed ductal-endocrine carcinoma 9.9 CALB2 NCAM1
27 nephrogenic adenofibroma 9.9 NCAM1 WT1
28 malignant mesenchymoma 9.8 NCAM1 WT1
29 hematologic cancer 9.8 NCAM1 WT1
30 acute promyelocytic leukemia 9.8 NCAM1 WT1
31 pheochromocytoma 9.8 CALB2 NCAM1
32 leukemia, acute myeloid 9.6 NCAM1 WT1

Graphical network of the top 20 diseases related to Fallopian Tube Carcinosarcoma:



Diseases related to Fallopian Tube Carcinosarcoma

Symptoms & Phenotypes for Fallopian Tube Carcinosarcoma

Drugs & Therapeutics for Fallopian Tube Carcinosarcoma

Drugs for Fallopian Tube Carcinosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 1 41575-94-4 10339178 38904 498142
2
Bevacizumab Approved, Investigational Phase 1 216974-75-3
3
Paclitaxel Approved, Vet_approved Phase 1 33069-62-4 36314
4
Cisplatin Approved Phase 1 15663-27-1 2767 441203 84093
5
Veliparib Investigational Phase 1 912444-00-9 11960529
6 Antineoplastic Agents, Phytogenic Phase 1
7 Poly(ADP-ribose) Polymerase Inhibitors Phase 1
8 Immunoglobulins Phase 1
9 Angiogenesis Inhibitors Phase 1
10 Antibodies, Monoclonal Phase 1
11 Immunologic Factors Phase 1
12 Antibodies Phase 1
13 Endothelial Growth Factors Phase 1
14 Antimitotic Agents Phase 1
15 Immunoglobulin G Phase 1
16 Angiogenesis Modulating Agents Phase 1
17 Albumin-Bound Paclitaxel Phase 1
18 Mitogens Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer Active, not recruiting NCT00989651 Phase 1 Carboplatin;Cisplatin;Paclitaxel;Veliparib
2 The Effects of Moderate Exercise on Distress, Quality of Life, and Biomarkers of Angiogenesis and Chronic Stress in Ovarian Cancer Survivors Recruiting NCT03641287 Not Applicable

Search NIH Clinical Center for Fallopian Tube Carcinosarcoma

Genetic Tests for Fallopian Tube Carcinosarcoma

Anatomical Context for Fallopian Tube Carcinosarcoma

MalaCards organs/tissues related to Fallopian Tube Carcinosarcoma:

41
Endothelial, Ovary, Testis, Myeloid

Publications for Fallopian Tube Carcinosarcoma

Variations for Fallopian Tube Carcinosarcoma

Expression for Fallopian Tube Carcinosarcoma

Search GEO for disease gene expression data for Fallopian Tube Carcinosarcoma.

Pathways for Fallopian Tube Carcinosarcoma

Pathways related to Fallopian Tube Carcinosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.75 NCAM1 WT1

GO Terms for Fallopian Tube Carcinosarcoma

Sources for Fallopian Tube Carcinosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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