MCID: FLL014
MIFTS: 23

Fallopian Tube Transitional Cell Carcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Fallopian Tube Transitional Cell Carcinoma

MalaCards integrated aliases for Fallopian Tube Transitional Cell Carcinoma:

Name: Fallopian Tube Transitional Cell Carcinoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4008
NCIt 49 C40104
UMLS 71 C1517128

Summaries for Fallopian Tube Transitional Cell Carcinoma

Disease Ontology : 12 A fallopian tube carcinoma that derives from epithelial transitional cells.

MalaCards based summary : Fallopian Tube Transitional Cell Carcinoma is related to transitional cell carcinoma and adenocarcinoma. An important gene associated with Fallopian Tube Transitional Cell Carcinoma is APOLD1 (Apolipoprotein L Domain Containing 1), and among its related pathways/superpathways are PEDF Induced Signaling and PI3K-Akt signaling pathway. The drugs Paclitaxel and Gemcitabine have been mentioned in the context of this disorder. Related phenotype is integument.

Related Diseases for Fallopian Tube Transitional Cell Carcinoma

Diseases related to Fallopian Tube Transitional Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
# Related Disease Score Top Affiliating Genes
1 transitional cell carcinoma 10.1
2 adenocarcinoma 10.1
3 rare tumor 10.1
4 linitis plastica 10.0 ERBB2 APOLD1
5 fallopian tube endometrioid adenocarcinoma 10.0 ERBB2 APOLD1
6 rectum adenocarcinoma 10.0 ERBB2 APOLD1
7 iritis 9.9 TNFRSF1B EPO
8 ascending colon cancer 9.8 CSF3 APOLD1
9 pneumocystosis 9.7 TNFRSF1B CSF3
10 pyoderma 9.7 TNFRSF1B CSF3
11 female breast cancer 9.7 ERBB2 CSF3
12 acute radiation syndrome 9.7 EPO CSF3
13 retinitis pigmentosa and erythrocytic microcytosis 9.7 EPO CSF3
14 refractory anemia 9.7 EPO CSF3
15 hair disease 9.7 ERBB2 CSF3
16 poems syndrome 9.7 EPO CSF3
17 hypersplenism 9.7 EPO CSF3
18 acquired immunodeficiency syndrome 9.6 TNFRSF1B EPO
19 hemoglobinuria 9.6 EPO CSF3
20 blood coagulation disease 9.6 EPO CSF3
21 fallopian tube serous adenocarcinoma 9.6 TNFRSF1B EPO APOLD1
22 aspergillosis 9.6 TNFRSF1B CSF3
23 pulmonary edema 9.6 EPO CSF3
24 sickle cell anemia 9.6 EPO CSF3
25 thrombocytosis 9.5 EPO CSF3
26 bone marrow cancer 9.5 EPO CSF3
27 blood platelet disease 9.4 EPO CSF3
28 exanthem 9.4 TNFRSF1B ERBB2 CSF3
29 pancytopenia 9.3 EPO CSF3
30 miliary tuberculosis 9.3 TNFRSF1B EPO CSF3
31 myeloma, multiple 9.2 ERBB2 EPO CSF3
32 leukemia, chronic myeloid 9.2 ERBB2 EPO CSF3
33 thrombocytopenia 9.2 ERBB2 EPO CSF3
34 polycythemia vera 9.2 EPO CSF3
35 leukemia, acute myeloid 9.1 ERBB2 EPO CSF3
36 myelodysplastic syndrome 8.9 TNFRSF1B ERBB2 EPO CSF3
37 ovarian clear cell cystadenocarcinoma 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1
38 ovarian clear cell malignant adenofibroma 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1
39 mixed epithelial tumor of ovary 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1
40 fallopian tube mucinous adenocarcinoma 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1

Graphical network of the top 20 diseases related to Fallopian Tube Transitional Cell Carcinoma:



Diseases related to Fallopian Tube Transitional Cell Carcinoma

Symptoms & Phenotypes for Fallopian Tube Transitional Cell Carcinoma

MGI Mouse Phenotypes related to Fallopian Tube Transitional Cell Carcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.92 CSF3 EPO ERBB2 TNFRSF1B

Drugs & Therapeutics for Fallopian Tube Transitional Cell Carcinoma

Drugs for Fallopian Tube Transitional Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
2
Gemcitabine Approved Phase 2 95058-81-4 60750
3
Topotecan Approved, Investigational Phase 2 123948-87-8, 119413-54-6 60700
4
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
5
Iodine Approved, Investigational Phase 2 7553-56-2 807
6 Anti-Bacterial Agents Phase 2
7 Anti-Infective Agents Phase 2
8 Immunologic Factors Phase 2
9 Albumin-Bound Paclitaxel Phase 2
10 Antibiotics, Antitubercular Phase 2
11 Antimitotic Agents Phase 2
12 Antimetabolites Phase 2
13 Immunosuppressive Agents Phase 2
14 topoisomerase I inhibitors Phase 2
15 Topoisomerase Inhibitors Phase 2
16
Liposomal doxorubicin Phase 2 31703
17 Antiviral Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Phase II Trial of a Genetically Engineered NIS-Expressing Strain of Measles Virus Versus Investigator's Choice Chemotherapy for Patients With Platinum-Resistant Ovarian, Fallopian, or Peritoneal Cancer Recruiting NCT02364713 Phase 2 Gemcitabine Hydrochloride;Paclitaxel;Pegylated Liposomal Doxorubicin Hydrochloride;Topotecan Hydrochloride

Search NIH Clinical Center for Fallopian Tube Transitional Cell Carcinoma

Genetic Tests for Fallopian Tube Transitional Cell Carcinoma

Anatomical Context for Fallopian Tube Transitional Cell Carcinoma

Publications for Fallopian Tube Transitional Cell Carcinoma

Articles related to Fallopian Tube Transitional Cell Carcinoma:

# Title Authors PMID Year
1
Primary fallopian tube transitional cell carcinoma. 61
25162143 2015

Variations for Fallopian Tube Transitional Cell Carcinoma

Expression for Fallopian Tube Transitional Cell Carcinoma

Search GEO for disease gene expression data for Fallopian Tube Transitional Cell Carcinoma.

Pathways for Fallopian Tube Transitional Cell Carcinoma

Pathways related to Fallopian Tube Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.05 TNFRSF1B ERBB2 EPO CSF3
2
Show member pathways
12.33 ERBB2 EPO CSF3
3 11.43 EPO CSF3
4 11.29 ERBB2 EPO
5 11.15 EPO CSF3
6 10.65 TNFRSF1B CSF3
7 10.3 EPO CSF3

GO Terms for Fallopian Tube Transitional Cell Carcinoma

Biological processes related to Fallopian Tube Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.33 ERBB2 EPO CSF3
2 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.26 EPO CSF3
3 cellular response to growth factor stimulus GO:0071363 8.96 TNFRSF1B ERBB2
4 negative regulation of neuron death GO:1901215 8.8 TNFRSF1B EPO CSF3

Sources for Fallopian Tube Transitional Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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