MCID: FLL014
MIFTS: 26

Fallopian Tube Transitional Cell Carcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Fallopian Tube Transitional Cell Carcinoma

MalaCards integrated aliases for Fallopian Tube Transitional Cell Carcinoma:

Name: Fallopian Tube Transitional Cell Carcinoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4008
NCIt 49 C40104
UMLS 71 C1517128

Summaries for Fallopian Tube Transitional Cell Carcinoma

Disease Ontology : 12 A fallopian tube carcinoma that derives from epithelial transitional cells.

MalaCards based summary : Fallopian Tube Transitional Cell Carcinoma is related to adenocarcinoma and transitional cell carcinoma. An important gene associated with Fallopian Tube Transitional Cell Carcinoma is APOLD1 (Apolipoprotein L Domain Containing 1), and among its related pathways/superpathways are PEDF Induced Signaling and PI3K-Akt signaling pathway. The drugs Iodine and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include myeloid, bone marrow and bone, and related phenotype is integument.

Related Diseases for Fallopian Tube Transitional Cell Carcinoma

Diseases related to Fallopian Tube Transitional Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 10.3
2 transitional cell carcinoma 10.1
3 linitis plastica 10.0 ERBB2 APOLD1
4 fallopian tube endometrioid adenocarcinoma 10.0 ERBB2 APOLD1
5 rectum adenocarcinoma 10.0 ERBB2 APOLD1
6 iritis 9.9 TNFRSF1B EPO
7 ascending colon cancer 9.8 CSF3 APOLD1
8 pneumocystosis 9.7 TNFRSF1B CSF3
9 pyoderma 9.7 TNFRSF1B CSF3
10 female breast cancer 9.7 ERBB2 CSF3
11 acute radiation syndrome 9.7 EPO CSF3
12 retinitis pigmentosa and erythrocytic microcytosis 9.7 EPO CSF3
13 refractory anemia 9.7 EPO CSF3
14 hair disease 9.7 ERBB2 CSF3
15 poems syndrome 9.7 EPO CSF3
16 hypersplenism 9.7 EPO CSF3
17 acquired immunodeficiency syndrome 9.6 TNFRSF1B EPO
18 hemoglobinuria 9.6 EPO CSF3
19 blood coagulation disease 9.6 EPO CSF3
20 fallopian tube serous adenocarcinoma 9.6 TNFRSF1B EPO APOLD1
21 aspergillosis 9.6 TNFRSF1B CSF3
22 pulmonary edema 9.6 EPO CSF3
23 sickle cell anemia 9.6 EPO CSF3
24 thrombocytosis 9.5 EPO CSF3
25 bone marrow cancer 9.5 EPO CSF3
26 blood platelet disease 9.4 EPO CSF3
27 exanthem 9.4 TNFRSF1B ERBB2 CSF3
28 pancytopenia 9.3 EPO CSF3
29 miliary tuberculosis 9.3 TNFRSF1B EPO CSF3
30 myeloma, multiple 9.2 ERBB2 EPO CSF3
31 leukemia, chronic myeloid 9.2 ERBB2 EPO CSF3
32 thrombocytopenia 9.2 ERBB2 EPO CSF3
33 polycythemia vera 9.2 EPO CSF3
34 leukemia, acute myeloid 9.1 ERBB2 EPO CSF3
35 myelodysplastic syndrome 8.9 TNFRSF1B ERBB2 EPO CSF3
36 ovarian clear cell cystadenocarcinoma 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1
37 ovarian clear cell malignant adenofibroma 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1
38 mixed epithelial tumor of ovary 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1
39 fallopian tube mucinous adenocarcinoma 8.6 TNFRSF1B ERBB2 EPO CSF3 APOLD1

Graphical network of the top 20 diseases related to Fallopian Tube Transitional Cell Carcinoma:



Diseases related to Fallopian Tube Transitional Cell Carcinoma

Symptoms & Phenotypes for Fallopian Tube Transitional Cell Carcinoma

MGI Mouse Phenotypes related to Fallopian Tube Transitional Cell Carcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.92 CSF3 EPO ERBB2 TNFRSF1B

Drugs & Therapeutics for Fallopian Tube Transitional Cell Carcinoma

Drugs for Fallopian Tube Transitional Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iodine Approved, Investigational Phase 2 7553-56-2 807
2
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
3
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
4
Topotecan Approved, Investigational Phase 2 119413-54-6, 123948-87-8 60700
5
Gemcitabine Approved Phase 2 95058-81-4 60750
6 Anti-Bacterial Agents Phase 2
7 Immunologic Factors Phase 2
8 topoisomerase I inhibitors Phase 2
9 Antibiotics, Antitubercular Phase 2
10 Anti-Infective Agents Phase 2
11 Antimitotic Agents Phase 2
12 Antiviral Agents Phase 2
13 Topoisomerase Inhibitors Phase 2
14
Liposomal doxorubicin Phase 2 31703
15 Immunosuppressive Agents Phase 2
16 Albumin-Bound Paclitaxel Phase 2
17 Antimetabolites Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Phase II Trial of a Genetically Engineered NIS-Expressing Strain of Measles Virus Versus Investigator's Choice Chemotherapy for Patients With Platinum-Resistant Ovarian, Fallopian, or Peritoneal Cancer Recruiting NCT02364713 Phase 2 Gemcitabine Hydrochloride;Paclitaxel;Pegylated Liposomal Doxorubicin Hydrochloride;Topotecan Hydrochloride

Search NIH Clinical Center for Fallopian Tube Transitional Cell Carcinoma

Genetic Tests for Fallopian Tube Transitional Cell Carcinoma

Anatomical Context for Fallopian Tube Transitional Cell Carcinoma

MalaCards organs/tissues related to Fallopian Tube Transitional Cell Carcinoma:

40
Myeloid, Bone Marrow, Bone, Colon, Breast, Ovary

Publications for Fallopian Tube Transitional Cell Carcinoma

Articles related to Fallopian Tube Transitional Cell Carcinoma:

# Title Authors PMID Year
1
Primary fallopian tube transitional cell carcinoma. 61
25162143 2015

Variations for Fallopian Tube Transitional Cell Carcinoma

Expression for Fallopian Tube Transitional Cell Carcinoma

Search GEO for disease gene expression data for Fallopian Tube Transitional Cell Carcinoma.

Pathways for Fallopian Tube Transitional Cell Carcinoma

Pathways related to Fallopian Tube Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.05 TNFRSF1B ERBB2 EPO CSF3
2
Show member pathways
12.33 ERBB2 EPO CSF3
3 11.43 EPO CSF3
4 11.29 ERBB2 EPO
5 11.15 EPO CSF3
6 10.65 TNFRSF1B CSF3
7 10.3 EPO CSF3

GO Terms for Fallopian Tube Transitional Cell Carcinoma

Biological processes related to Fallopian Tube Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.33 ERBB2 EPO CSF3
2 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.26 EPO CSF3
3 cellular response to growth factor stimulus GO:0071363 8.96 TNFRSF1B ERBB2
4 negative regulation of neuron death GO:1901215 8.8 TNFRSF1B EPO CSF3

Sources for Fallopian Tube Transitional Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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