Familial Alzheimer-Like Prion Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Familial Alzheimer-Like Prion Disease

MalaCards integrated aliases for Familial Alzheimer-Like Prion Disease:

Name: Familial Alzheimer-Like Prion Disease ⁶⁰

Characteristics:

Orphanet epidemiological data:

⁶⁰

familial alzheimer-like prion disease
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Adult;

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ³⁵

Certain infectious and parasitic diseases

Viral infections of the central nervous system

Atypical virus infections of central nervous system

Other atypical virus infections of central nervous system

Orphanet: ⁶⁰

Rare neurological diseases

External Ids:

ICD10 via Orphanet ³⁵ A81.8

Orphanet ⁶⁰ ORPHA280397

SNOMED-CT via HPO ⁷⁰ 18963009 21061000119107 274667000 more

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Summaries for Familial Alzheimer-Like Prion Disease

MalaCards based summary : Familial Alzheimer-Like Prion Disease An important gene associated with Familial Alzheimer-Like Prion Disease is PRNP (Prion Protein). Related phenotypes are emotional lability and depressivity

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Related Diseases for Familial Alzheimer-Like Prion Disease

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Symptoms & Phenotypes for Familial Alzheimer-Like Prion Disease

Human phenotypes related to Familial Alzheimer-Like Prion Disease:

⁶⁰ ³³ (show all 12)

#	Description	HPO Frequency	Orphanet Frequency	HPO Source Accession
1	emotional lability ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0000712
2	depressivity ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0000716
3	sleep disturbance ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0002360
4	attention deficit hyperactivity disorder ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0007018
5	anxiety ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0000739
6	specific learning disability ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0001328
7	perseveration ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0030223
8	deficit in phonologic short-term memory ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0002549
9	abdominal symptom ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0011458
10	jaw pain ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0040264
11	behavioral abnormality ⁶⁰		Very frequent (99-80%)
12	cognitive impairment ⁶⁰		Very frequent (99-80%)

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Drugs & Therapeutics for Familial Alzheimer-Like Prion Disease

Search Clinical Trials , NIH Clinical Center for Familial Alzheimer-Like Prion Disease

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Genetic Tests for Familial Alzheimer-Like Prion Disease

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Anatomical Context for Familial Alzheimer-Like Prion Disease

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Publications for Familial Alzheimer-Like Prion Disease

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Genes for Familial Alzheimer-Like Prion Disease

Genes related to Familial Alzheimer-Like Prion Disease (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	PRNP	Prion Protein	Protein Coding	350	Causative germline mutation ⁶⁰

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Variations for Familial Alzheimer-Like Prion Disease

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Expression for Familial Alzheimer-Like Prion Disease

Search GEO for disease gene expression data for Familial Alzheimer-Like Prion Disease.

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Pathways for Familial Alzheimer-Like Prion Disease

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GO Terms for Familial Alzheimer-Like Prion Disease

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Sources for Familial Alzheimer-Like Prion Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

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¹⁶ DrugBank

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¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia