MCID: FML334
MIFTS: 24

Familial Candidiasis

Categories: Genetic diseases, Rare diseases, Blood diseases, Skin diseases, Immune diseases, Infectious diseases

Aliases & Classifications for Familial Candidiasis

MalaCards integrated aliases for Familial Candidiasis:

Name: Familial Candidiasis 25
Familial Chronic Mucocutaneous Candidiasis 25 73
Candidiasis, Familial, 2 73

Classifications:



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Summaries for Familial Candidiasis

Genetics Home Reference : 25 Familial candidiasis is an inherited tendency to develop infections caused by a type of fungus called Candida. Affected individuals typically have infections of the skin, the nails, and the moist lining of body cavities (mucous membranes). These infections are recurrent and persistent, which means they come back repeatedly and can last a long time. This pattern of infection is called chronic mucocutaneous candidiasis.

MalaCards based summary : Familial Candidiasis, also known as familial chronic mucocutaneous candidiasis, is related to candidiasis, familial, 2 and chronic mucocutaneous candidiasis. An important gene associated with Familial Candidiasis is CANDN1 (Candidiasis, Nail 1 (With ICAM1 Deficiency)), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Cytokine production by Th17 cells in CF (Mouse model). Affiliated tissues include skin.

Related Diseases for Familial Candidiasis

Graphical network of the top 20 diseases related to Familial Candidiasis:



Diseases related to Familial Candidiasis

Symptoms & Phenotypes for Familial Candidiasis

Drugs & Therapeutics for Familial Candidiasis

Search Clinical Trials , NIH Clinical Center for Familial Candidiasis

Genetic Tests for Familial Candidiasis

Anatomical Context for Familial Candidiasis

MalaCards organs/tissues related to Familial Candidiasis:

41
Skin

Publications for Familial Candidiasis

Articles related to Familial Candidiasis:

# Title Authors Year
1
Autosomal dominant familial chronic mucocutaneous candidiasis associated with acne rosacea. ( 16284681 )
2005
2
Fungal intracranial aneurysm in a child with familial chronic mucocutaneous candidiasis. ( 10445344 )
1999
3
Case report: familial chronic mucocutaneous candidiasis complicated by deep candida infection. ( 8160723 )
1994
4
[Familial chronic mucocutaneous candidiasis. Study of 2 families]. ( 6330471 )
1984
5
Familial chronic mucocutaneous candidiasis successfully treated with oral ketoconazole. ( 6256921 )
1981

Variations for Familial Candidiasis

Expression for Familial Candidiasis

Search GEO for disease gene expression data for Familial Candidiasis.

Pathways for Familial Candidiasis

Pathways related to Familial Candidiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.29 IL17F IL17RA
2
Show member pathways
10.59 IL17F IL17RA

GO Terms for Familial Candidiasis

Biological processes related to Familial Candidiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.26 IL17F IL17RA
2 interleukin-17-mediated signaling pathway GO:0097400 9.16 IL17F IL17RA
3 regulation of interleukin-6 biosynthetic process GO:0045408 8.96 CARD9 IL17F
4 regulation of interleukin-2 biosynthetic process GO:0045076 8.62 CARD9 IL17F

Sources for Familial Candidiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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