MCID: FRS001
MIFTS: 18

Far Eastern Spotted Fever

Categories: Infectious diseases

Aliases & Classifications for Far Eastern Spotted Fever

MalaCards integrated aliases for Far Eastern Spotted Fever:

Name: Far Eastern Spotted Fever 12 15 71
Rickettsia Heilongjiangensis Spotted Fever 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050046
UMLS 71 C3532354

Summaries for Far Eastern Spotted Fever

Disease Ontology : 12 A spotted fever that has material basis in Rickettsia heilongjiangensis, which is transmitted by ticks (Haemaphysalis concinna). The infection has symptom fever, has symptom eschar, has symptom maculopapular rash, and has symptom regional adenopathy.

MalaCards based summary : Far Eastern Spotted Fever, also known as rickettsia heilongjiangensis spotted fever, is related to spotted fever and cerebellar ataxia type 9, and has symptoms including fever, maculopapular rash and eschar. An important gene associated with Far Eastern Spotted Fever is GLRX5 (Glutaredoxin 5), and among its related pathways/superpathways is Spinocerebellar ataxia. Affiliated tissues include t cells and endothelial.

Related Diseases for Far Eastern Spotted Fever

Diseases related to Far Eastern Spotted Fever via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 spotted fever 10.3
2 cerebellar ataxia type 9 9.7 KCNC3 ATXN10
3 cerebellar disease 9.7 KCNC3 ATXN10
4 dentatorubral-pallidoluysian atrophy 9.6 KCNC3 ATXN10
5 autosomal dominant cerebellar ataxia 9.5 KCNC3 ATXN10
6 hereditary ataxia 9.4 KCNC3 ATXN10

Graphical network of the top 20 diseases related to Far Eastern Spotted Fever:



Diseases related to Far Eastern Spotted Fever

Symptoms & Phenotypes for Far Eastern Spotted Fever

Symptoms:

12
  • fever
  • maculopapular rash
  • eschar
  • regional adenopathy

Drugs & Therapeutics for Far Eastern Spotted Fever

Search Clinical Trials , NIH Clinical Center for Far Eastern Spotted Fever

Genetic Tests for Far Eastern Spotted Fever

Anatomical Context for Far Eastern Spotted Fever

MalaCards organs/tissues related to Far Eastern Spotted Fever:

40
T Cells, Endothelial

Publications for Far Eastern Spotted Fever

Articles related to Far Eastern Spotted Fever:

# Title Authors PMID Year
1
Identification of a Ribosomal Protein RpsB as a Surface-Exposed Protein and Adhesin of Rickettsia heilongjiangensis. 61
31360728 2019
2
Genomic Features of Rickettsia heilongjiangensis Revealed by Intraspecies Comparison and Detailed Comparison With Rickettsia japonica. 61
31866968 2019
3
Enhanced Expression of T-Cell Immunoglobulin and Mucin Domain Protein 3 in Endothelial Cells Facilitates Intracellular Killing of Rickettsia heilongjiangensis. 61
26401029 2016
4
Genomic and comparative genomic analyses of Rickettsia heilongjiangensis provide insight into its evolution and pathogenesis. 61
24924907 2014
5
Microarray of surface-exposed proteins of Rickettsia heilongjiangensis for serodiagnosis of Far-eastern spotted fever. 61
24938647 2014
6
Recombinant protein YbgF induces protective immunity against Rickettsia heilongjiangensis infection in C3H/HeN mice. 61
24113261 2013
7
Proteome analysis and serological characterization of surface-exposed proteins of Rickettsia heilongjiangensis. 61
23894656 2013
8
Complete genome sequence of Rickettsia heilongjiangensis, an emerging tick-transmitted human pathogen. 61
21914880 2011
9
Exploratory study on pathogenesis of far-eastern spotted fever. 61
21896812 2011
10
[Far-eastern spotted fever: description of new infectious disease]. 61
18756784 2008

Variations for Far Eastern Spotted Fever

Expression for Far Eastern Spotted Fever

Search GEO for disease gene expression data for Far Eastern Spotted Fever.

Pathways for Far Eastern Spotted Fever

Pathways related to Far Eastern Spotted Fever according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.75 KCNC3 ATXN10

GO Terms for Far Eastern Spotted Fever

Cellular components related to Far Eastern Spotted Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 9.13 KCNC3 GLRX5 ATXN10
2 dendrite GO:0030425 8.92 URI1 KCNC3 GLRX5 ATXN10

Sources for Far Eastern Spotted Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....