Aliases & Classifications for Farsightedness

MalaCards integrated aliases for Farsightedness:

Name: Farsightedness 25
Hypermetropia 25 29 6 32
Hyperopia 25 54
Long-Sightedness 25
Far-Sightedness 25
Long-Sighted 25
Farsighted 25

Classifications:



External Ids:

ICD10 32 H52.0

Summaries for Farsightedness

Genetics Home Reference : 25 Farsightedness, also known as hyperopia, is an eye condition that causes blurry near vision. People who are farsighted have more trouble seeing things that are close up (such as when reading or using a computer) than things that are far away (such as when driving). For normal vision, light passes through the clear cornea at the front of the eye and is focused by the lens onto the surface of the retina, which is the lining of the back of the eye that contains light-sensing cells. Some people who are farsighted have eyeballs that are too short from front to back. Others have a cornea or lens that is abnormally shaped. These changes cause light entering the eye to be focused too far back, behind the retina instead of on its surface. It is this difference that causes nearby objects to appear blurry. In a person with this condition, one eye may be more farsighted than the other. If it is not treated with corrective lenses or surgery, farsightedness can lead to eye strain, excess tearing, squinting, frequent blinking, headaches, difficulty reading, and problems with hand-eye coordination. However, some children with the eye changes characteristic of farsightedness do not notice any blurring of their vision or related signs and symptoms early in life. Other parts of the visual system are able to compensate, at least temporarily, for the changes that would otherwise cause light to be focused in the wrong place. Most infants are born with a mild degree of farsightedness, which goes away on its own as the eyes grow. In some children, farsightedness persists or is more severe. Children with a severe degree of farsightedness, described as high hyperopia, are at an increased risk of developing other eye conditions, particularly "lazy eye" (amblyopia) and eyes that do not look in the same direction (strabismus). These conditions can cause significant visual impairment. In general, older adults also have difficulty seeing things close up; this condition is known as presbyopia. Presbyopia develops as the lens of the eye becomes thicker and less flexible with age and the muscles surrounding the lens weaken. Although it is sometimes described as "farsightedness," presbyopia is caused by a different mechanism than hyperopia and is considered a separate condition.

MalaCards based summary : Farsightedness, also known as hypermetropia, is related to hypertelorism and cryptorchidism, unilateral or bilateral. An important gene associated with Farsightedness is ANKRD11 (Ankyrin Repeat Domain 11). The drugs Atropine and Ketorolac have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and testes, and related phenotypes are embryo and vision/eye

Wikipedia : 74 Far-sightedness, also known as hypermetropia, is a condition of the eye in which light is focused... more...

Related Diseases for Farsightedness

Diseases related to Farsightedness via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 183)
# Related Disease Score Top Affiliating Genes
1 hypertelorism 29.6 NSD1 ANKRD11
2 cryptorchidism, unilateral or bilateral 29.6 NSD1 ANKRD11
3 hyperopia, high 12.2
4 microphthalmia with hyperopia, retinal degeneration, macrophakia, and dental anomalies 12.2
5 syndromic hyperopia 12.2
6 rare hyperopia and astigmatism 12.2
7 stapes ankylosis with broad thumbs and toes 12.1
8 pilodental dysplasia with refractive errors 11.8
9 microphthalmia 11.5
10 microphthalmia, isolated 1 11.4
11 nanophthalmos 11.4
12 night blindness, congenital stationary, type 1a 11.4
13 nanophthalmos 2 11.4
14 leber plus disease 11.4
15 cornea plana 2, autosomal recessive 11.3
16 leber congenital amaurosis 6 11.3
17 senior-loken syndrome 1 11.3
18 nanophthalmos 4 11.3
19 leber congenital amaurosis 10 11.2
20 leber congenital amaurosis 13 11.2
21 kenny-caffey syndrome, type 2 11.1
22 vitreoretinochoroidopathy 11.1
23 leber congenital amaurosis 1 11.1
24 leber congenital amaurosis 2 11.1
25 kenny-caffey syndrome, type 1 11.1
26 retinitis pigmentosa 12 11.1
27 microphthalmia, isolated 5 11.1
28 leber congenital amaurosis 7 11.1
29 leber congenital amaurosis 8 11.1
30 leber congenital amaurosis 11 11.1
31 familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis 11.1
32 blepharophimosis, ptosis, and epicanthus inversus 11.1
33 myhre syndrome 11.1
34 microcephalic osteodysplastic primordial dwarfism, type ii 11.1
35 achromatopsia 2 11.1
36 kaufman oculocerebrofacial syndrome 11.1
37 retinoschisis 1, x-linked, juvenile 11.1
38 fontaine progeroid syndrome 11.1
39 helsmoortel-van der aa syndrome 11.1
40 white-sutton syndrome 11.1
41 amblyopia 11.1
42 achromatopsia 11.1
43 refractive error 11.1
44 hivep2-related intellectual disability 11.1
45 cornea plana 1, autosomal dominant 11.0
46 retinal degeneration with nanophthalmos, cystic macular degeneration, and angle closure glaucoma 11.0
47 leber congenital amaurosis 3 11.0
48 leber congenital amaurosis 4 11.0
49 leber congenital amaurosis 5 11.0
50 craniosynostosis 2 11.0

Graphical network of the top 20 diseases related to Farsightedness:



Diseases related to Farsightedness

Symptoms & Phenotypes for Farsightedness

MGI Mouse Phenotypes related to Farsightedness:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 9.26 ANKRD11 NOG NSD1 TMEM98
2 vision/eye MP:0005391 8.92 ANKRD11 GUCY2D NOG TMEM98

Drugs & Therapeutics for Farsightedness

Drugs for Farsightedness (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 79)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Atropine Approved, Vet_approved Phase 4 51-55-8, 5908-99-6 174174
2
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
3
Nepafenac Approved, Investigational Phase 4 78281-72-8 151075
4 Propoxycaine Approved Phase 4 86-43-1
5 Mydriatics Phase 4
6 Respiratory System Agents Phase 4
7 Parasympatholytics Phase 4
8 Anti-Arrhythmia Agents Phase 4
9 Muscarinic Antagonists Phase 4
10 Bronchodilator Agents Phase 4
11 Anti-Asthmatic Agents Phase 4
12 Cholinergic Antagonists Phase 4
13 Ketorolac Tromethamine Phase 4
14 Analgesics, Non-Narcotic Phase 4
15 Analgesics Phase 4
16 Anti-Inflammatory Agents Phase 4
17 Cyclooxygenase Inhibitors Phase 4
18 Antirheumatic Agents Phase 4
19 Anti-Inflammatory Agents, Non-Steroidal Phase 4
20 Pharmaceutical Solutions Phase 4
21 Anesthetics Phase 4
22 Proxymetacaine Phase 4
23 Anesthetics, Local Phase 4
24
Zinc Approved, Investigational Phase 3 7440-66-6 32051
25
Tocopherol Approved, Investigational Phase 3 1406-66-2, 54-28-4 14986
26
Zinc oxide Approved Phase 3 1314-13-2
27
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
28
Vitamin C Approved, Nutraceutical Phase 3 50-81-7 5785 54670067
29
Beta carotene Approved, Nutraceutical Phase 3 7235-40-7
30 Tocotrienol Investigational Phase 3 6829-55-6
31 Trace Elements Phase 3
32 Micronutrients Phase 3
33 Vitamins Phase 3
34 Nutrients Phase 3
35 Carotenoids Phase 3
36 Antioxidants Phase 3
37 Tocotrienols Phase 3
38 Protective Agents Phase 3
39 Tocopherols Phase 3
40
Levofloxacin Approved, Investigational Phase 1, Phase 2 100986-85-4 149096
41
Ofloxacin Approved Phase 1, Phase 2 82419-36-1 4583
42
Betamethasone Approved, Vet_approved Phase 1, Phase 2 378-44-9 9782
43
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 1, Phase 2 83-88-5 493570
44
Folic acid Approved, Nutraceutical, Vet_approved Phase 1, Phase 2 59-30-3 6037
45 Anti-Infective Agents Phase 1, Phase 2
46 Cytochrome P-450 Enzyme Inhibitors Phase 1, Phase 2
47 Hormones Phase 1, Phase 2
48 Anti-Bacterial Agents Phase 1, Phase 2
49 Hormone Antagonists Phase 1, Phase 2
50 glucocorticoids Phase 1, Phase 2

Interventional clinical trials:

(show top 50) (show all 141)
# Name Status NCT ID Phase Drugs
1 A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser Using LASIK Unknown status NCT02071576 Phase 4
2 A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser in Asian Eyes Using LASIK Unknown status NCT01977807 Phase 4
3 A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia Unknown status NCT02112968 Phase 4
4 PHASE IV STUDY # 1162. Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism Unknown status NCT01628146 Phase 4
5 Infiltrative Events During Silicone Hydrogel Daily Contact Lens (Daily Wear Corneal Infiltrative Event (DWCIE) Study) Completed NCT00937105 Phase 4
6 On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours Completed NCT03881670 Phase 4
7 A Prospective Study to Evaluate the Safety and Effectiveness of the Supracor Presbyopic Treatment Algorithm for Pseudophakic Eyes Using Lasik Completed NCT01387360 Phase 4
8 Corneal and Conjunctival Sensitivity and Staining Study Completed NCT00455455 Phase 4 Optifree RepleniSH Multipurpose Disinfecting Solution;ReNu Multiplus Multipurpose Solution
9 Double Masked Evaluation of Acular LS Versus Nevanac for Postoperative Pain Control in Eyes Undergoing PRK Completed NCT00347204 Phase 4 ketorolac (Acular LS);Nepafenac (Nevanac)
10 A Randomized Trial Comparing Daily Atropine Versus Weekend Atropine Completed NCT00094614 Phase 4 Atropine
11 Clinical Investigation of the Vision-R800 Device. Understanding the Value of High Precision Refractions and Lenses to Optometrists and Patients. Phase 2 Recruiting NCT04208750 Phase 4
12 Efficacy and Safety of Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK). Not yet recruiting NCT04283331 Phase 4 Proparacaine Ophthalmic
13 Intrastromal Correction of Ametropia by a Femtosecond Laser Unknown status NCT00928122 Phase 3
14 A Prospective Multicenter, Study to Evaluate the Safety and Effectiveness of the Presbyopia Algorithm for Hyperopia and Hyperopic Astigmatism Using LASIK Completed NCT00910403 Phase 3
15 Topography-Guided LASIK Using the ALLEGRETTO WAVE Eye-Q 400 Hz Excimer Laser System For the Treatment of Manifest and Cornea Based Myopic and Hyperopic Optical Errors Completed NCT01028378 Phase 3
16 An Open-Labeled, Multi-Center, Randomized Investigation of the VISA (Comfilcon A) Silicone Hydrogel Soft (Hydrophilic) Contact Lens for Use in a 7 Day Extended Wear Regimen Completed NCT00597467 Phase 3
17 Multipurpose Solution Compatibility With a Silicone Hydrogel Lens Completed NCT00520689 Phase 3
18 Effects of Vertical Prism on the Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria: A Randomized, Double-blinded, Placebo-controlled, Cross-over Study Completed NCT00785135 Phase 3
19 A Prospective Study to Evaluate the Safety and Effectiveness of the Presbyopic LASIK Algorithm Completed NCT01322919 Phase 3
20 Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old Completed NCT00944710 Phase 3 Atropine;Atropine
21 NEUROCOM: Cognitive Training for Patients With First Episode Schizophrenia Completed NCT00472862 Phase 3
22 Age-Related Eye Disease Study (AREDS) Completed NCT00000145 Phase 3
23 The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3) Recruiting NCT03140358 Phase 3 Atropine sulfate 0.01%;Placebo
24 Corneal Epithelium Repair and Therapy Using Autologous Limbal Stem Cell Transplantation Unknown status NCT02148016 Phase 1, Phase 2 Levofloxacin;Betamethasone;Limbal stem cells (LSCs)
25 Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions Completed NCT01024855 Phase 1, Phase 2
26 Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia? Completed NCT01308307 Phase 2
27 Enhancement of Emmetropization in Hyperopic Infants Terminated NCT00574717 Phase 1, Phase 2
28 A Multi-Center, Randomized, Controlled Evaluation of the Safety and Efficacy of LASIK With Cross-linking Performed With the KXL System and Photrexa ZD™ (Riboflavin Ophthalmic Solution) Compared to LASIK Alone for Hyperopia and Hyperopic Astigmatism Terminated NCT01893359 Phase 1, Phase 2 riboflavin ophthalmic solution, 0% dextran
29 Prospective, Single-center Clinical Trial of Subjects Scheduled to Undergo LASIK Surgery Requiring an Initial Corneal Flap. Completed NCT01556893 Phase 1
30 Investigation of Visual Plasticity by a Direct Current Stimulation of Occipital Cortex in Adult Amblyopia Completed NCT00097162 Phase 1
31 Posterior and Anterior Ocular Imaging With Spectral Domain Optical Coherence Tomography Unknown status NCT00926549
32 Prevalence of Chronic Angle Closure in Caucasian Hyperopic Subjects Unknown status NCT00823706
33 Clinical Trial of the Femtosecond Laser System VisuMax for Refractive Correction of Hyperopia by Means of Lenticule Extraction Unknown status NCT02316041
34 Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens (Hexafocon b) Test When Worn on a Daily Wear Basis in the Correction of Myopia/Hyperopia/Astigmatism/Presbyopia/ and Irregular Cornea. Unknown status NCT02812316
35 Accuracy of Welch Allyn Spot™ Vision Screener to Detect Amblyogenic Factors in Developmentally Delayed Children Unknown status NCT03479021
36 Development of a Validated Chart for Intermediate Vision Assessment Unknown status NCT02279446
37 Prescription of Full Optical Correction in Refractive Errors to Treat Esotropia in Children up to 3 Years Old Unknown status NCT02404324
38 A 180 Day, Multicenter Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses for Daily Wear Use in the Correction of Refractive Error With or Without Astigmatism in Non-diseased Eyes Unknown status NCT01058629
39 Changes of the Corneal Endothelial Cell Count After Artisan Phakic Intraocular Lens Implantation Unknown status NCT03266354
40 Accuracy of Intraocular Lens Power in High Myopia Unknown status NCT03394300
41 Comparison of Small Incision Lenticule Extraction (SMILE) and VisuMax Femtosecond Laser In Situ Keratomileusis (FemtoLASIK): A Randomized, Non-inferiority Trial Unknown status NCT01216475
42 Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution Completed NCT01809197
43 Correction of Hyperopia in Children Study Completed NCT00472212
44 Randomized Controlled, Double-Blind Trial of Investigation of the Effect of Different Eye Exercises on Hypermetropia in School-age Children Completed NCT03347734
45 Bilateral Refractive Amblyopia Treatment Study Completed NCT00305955
46 A Study to Evaluate the Safety and Effectiveness of the Technols 217z Zyoptix System for Hyperopia Completed NCT00348205
47 Corneal Wavefront-Guided PRK With Adjunctive Mitomycin-C for the Treatment of Hyperopia After Radial Keratotomy Completed NCT00917657
48 First-Sight Refractive Error Correction in the Developing World Completed NCT01598818
49 Improving Vision and Quality of Life in the Nursing Home Completed NCT00347620
50 A Prospective Study to Evaluate the Safety and Effectiveness of Wavefront-Guided Lasik Correction of Hyperopic Refractive Errors With the iDesign Advanced Wavescan Studio™ System and Star S4 IR™ Excimer Laser System Completed NCT01675479

Search NIH Clinical Center for Farsightedness

Genetic Tests for Farsightedness

Genetic tests related to Farsightedness:

# Genetic test Affiliating Genes
1 Hypermetropia 29

Anatomical Context for Farsightedness

MalaCards organs/tissues related to Farsightedness:

40
Eye, Retina, Testes, Endothelial, Cortex, Thyroid, Skin

Publications for Farsightedness

Articles related to Farsightedness:

(show top 50) (show all 691)
# Title Authors PMID Year
1
A novel mutation in the GUCY2D gene responsible for an early onset severe RP different from the usual GUCY2D-LCA phenotype. 54 61
15643614 2005
2
Ophthalmic findings in neonates receiving sildenafil. 61
31916341 2020
3
Associations between Attention-Deficit/Hyperactivity Disorder and Ocular Abnormalities in Children: A Population-based Study. 61
31878821 2020
4
Clinical characteristics and OCT analysis of a case series of posterior microphthalmos. 61
32184046 2020
5
Is the severity of refractive error dependent on the quantity and extent of retinal laser ablation for retinopathy of prematurity? 61
31554947 2020
6
[Application of nerve block in total knee arthroplasty under general anesthesia]. 61
32351092 2020
7
The hypermetropia of count István Tisza. 61
31918863 2020
8
Accuracy of noncycloplegic photorefraction using Spot photoscreener in detecting amblyopia risk factors in preschool children in an Indian eye clinic. 61
32057013 2020
9
Incidence of Keratoconus in Refractive Surgery Population of Vojvodina - Single Center Study. 61
32410891 2020
10
Progression Over 5 Years of Prelaminar Hyperreflective Lines to Optic Disc Drusen in the Copenhagen Child Cohort 2000 Eye Study. 61
32108119 2020
11
Clinical Features of Vitreomacular Traction Syndrome with Peripheral Vitreoretinal Adhesion. 61
32095069 2020
12
Wide Stromal Mapping Using an Anterior Segment Optical Coherence Tomography. 61
32210528 2020
13
Inter-Ocular Asymmetry in Anterior Corneal Aberrations Using Placido Disk-Based Topography. 61
32546953 2020
14
Familial Nanophthalmos Presenting with Spontaneous Uveal Effusion Syndrome. 61
30556758 2020
15
Vision impairment and refractive errors in refugees presenting to community optometry clinics in Victoria, Australia. 61
31773820 2019
16
Evidence-based preschool-age vision screening: health policy considerations. 61
31514739 2019
17
Eye Conditions in Infants and Children: Myopia and Hyperopia. 61
31454214 2019
18
A randomized clinical trial using atropine, cyclopentolate, and tropicamide to compare refractive outcome in hypermetropic children with a dark iris; skin pigmentation and crying as significant factors for hypermetropic outcome. 61
31234691 2019
19
Progressive High Hypermetropic Shift as a Refractive Surprise Following Glaucoma Filtration Surgery in a Phakic Child With Early-Onset Childhood Glaucoma Associated With Axenfeld-Rieger Anomaly. 61
31135590 2019
20
A novel variant of the human mitochondrial DnaJ protein, Tid1, associates with a human disease exhibiting developmental delay and polyneuropathy. 61
30770860 2019
21
Novel compound heterozygous mutations in OCA2 gene associated with non-syndromic oculocutaneous albinism in a Chinese Han patient: a case report. 61
31345173 2019
22
Post-operative analysis of pediatric esotropia associated with high hypermetropia. 61
31262252 2019
23
Visual Outcome of Preterm Infants Screened in a Tertiary Care Hospital. 61
31619904 2019
24
Comparative study of visual dysfunctions in 6-10-year-old very preterm- and full-term-born children. 61
29916121 2019
25
Lasik as a Solution for High Hypermetropia. 61
31402804 2019
26
Sensitivity and specificity of school nurse screening for hypermetropia and convergence insufficiency exophoria in primary schoolchildren in Denmark. 61
30338671 2019
27
Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice. 61
31048900 2019
28
A Case of Giant Macular Hole Progression after Rupture of a Giant Retinal Pigment Epithelial Detachment. 61
31692603 2019
29
How many challenges we may encounter in anterior megalophthalmos with white cataract: a case report. 61
31146719 2019
30
Prevalence of refractive errors; an evidence from the public high schools of Lahore, Pakistan. 61
31000845 2019
31
Choroidal thickness in normal Indian eyes using swept-source optical coherence tomography. 61
30672480 2019
32
Ametropia in children with headache. 61
31258579 2019
33
Efficacy of Smartphone-based Exercises in Conjunction with Modified Glasses Prescription in the Treatment of Convergence Insufficiency and Fusion Weakness. 61
30821632 2019
34
Clinical and surgical risk factors for consecutive exotropia. 61
29667435 2019
35
Comparison of 9.0 and 9.2 mm Flap Diameter Options of Femtosecond Laser In-Situ Keratomileusis for Hypermetropia and Hypermetropic Astigmatism. 61
31781379 2019
36
Evaluation of Corneal Higher-Order Aberrations by Scheimpflug-Placido Topography in Patients with Different Refractive Errors: A Retrospective Observational Study. 61
31275631 2019
37
[Diffuse choroidal hemangioma as a manifestation of Sturge-Weber syndrome (a clinical case study)]. 61
32015315 2019
38
Politicizing the Precautionary Principle: Why Disregarding Facts Should Not Pass for Farsightedness. 61
31507627 2019
39
Prevalence of, and risk factors for, presenting visual impairment: findings from a vision screening programme based on UK NSC guidance in a multi-ethnic population. 61
29899459 2018
40
Impact of varying the definition of myopia on estimates of prevalence and associations with risk factors: time for an approach that serves research, practice and policy. 61
29437571 2018
41
Inequities in visual health and health services use in a rural region in Spain. 61
28599955 2018
42
Comparision of Optical Low Coherence Reflectometry Versus Ultrasonic Biometry in High Hypermetropia. 61
27898517 2018
43
Dynamic Changes in Schlemm Canal and Iridocorneal Angle Morphology During Accommodation in Children With Healthy Eyes: A Cross-Sectional Cohort Study. 61
30025073 2018
44
Pattern of refractive errors in Buraydah. How serious is the problem? 61
30022902 2018
45
Assessing the inclusion of primary school children in vision screening for refractive error program of India. 61
29941735 2018
46
Further delineation of the MECP2 duplication syndrome phenotype in 59 French male patients, with a particular focus on morphological and neurological features. 61
29618507 2018
47
Pattern and Prevalence of Refractive Error and Secondary Visual Impairment in Patients Attending a Tertiary Hospital in Dhulikhel, Nepal. 61
30636750 2018
48
Anterior Segment Changes during Accommodation in Accommodative Esotropia. 61
29376230 2018
49
Visual impairment and amblyopia in Malaysian pre-school children - The SEGPAEDS study. 61
29531199 2018
50
Ocular Disorders in Turkish Children with Sensorineural Hearıng Loss: A Cross-Sectional Study and Literature Review. 61
27627831 2018

Variations for Farsightedness

ClinVar genetic disease variations for Farsightedness:

6 ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 NSD1 NM_022455.4(NSD1):c.3839G>A (p.Trp1280Ter)SNV Pathogenic 159315 rs587784105 5:176662864-176662864 5:177235863-177235863
2 ANKRD11 NM_013275.6(ANKRD11):c.5317G>T (p.Glu1773Ter)SNV Pathogenic 242882 rs1114167291 16:89347633-89347633 16:89281225-89281225
3 46;XX;t(19;21)(q13.3;q22.3)dnTranslocation Pathogenic 268035
4 DMBX1 NM_172225.2(DMBX1):c.352C>T (p.Arg118Trp)SNV Likely pathogenic 183286 rs730882203 1:46976625-46976625 1:46510953-46510953
5 FGF14 NM_004115.3(FGF14):c.486dup (p.Arg163fs)duplication Likely pathogenic 598976 rs1566823361 13:102379082-102379083 13:101726732-101726733
6 TOPORS NM_005802.5(TOPORS):c.2666A>G (p.His889Arg)SNV Uncertain significance 523487 rs762457246 9:32541857-32541857 9:32541859-32541859
7 SLC9A6 NM_001042537.1(SLC9A6):c.1346C>A (p.Ala449Glu)SNV Uncertain significance 523398 rs1556619324 X:135098913-135098913 X:136016754-136016754
8 GFOD1 , MCUR1 , NOL7 , PHACTR1 , RANBP9 , RNF182 , SIRT5 , TBC1D7 GRCh37/hg19 6p24.1-23(chr6:12536624-13968949)copy number gain Uncertain significance 523282 6:12536624-13968949
9 C5orf17 , CDH10 , CDH12 , PRDM9 GRCh37/hg19 5p14.3-14.2(chr5:22308420-24492723)copy number gain Uncertain significance 523302 5:22308420-24492723

Expression for Farsightedness

Search GEO for disease gene expression data for Farsightedness.

Pathways for Farsightedness

GO Terms for Farsightedness

Biological processes related to Farsightedness according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 face morphogenesis GO:0060325 8.62 NOG ANKRD11

Sources for Farsightedness

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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