MCID: FST012
MIFTS: 9

Fasting Plasma Glucose Level Quantitative Trait Locus 1

Categories: Genetic diseases

Aliases & Classifications for Fasting Plasma Glucose Level Quantitative Trait Locus 1

MalaCards integrated aliases for Fasting Plasma Glucose Level Quantitative Trait Locus 1:

Name: Fasting Plasma Glucose Level Quantitative Trait Locus 1 57 29
Fasting Plasma Glucose Level Qtl 1 57 13
Fgqtl1 57

Classifications:



External Ids:

OMIM 57 612108

Summaries for Fasting Plasma Glucose Level Quantitative Trait Locus 1

OMIM : 57 Glucose is the major source of energy in humans, with levels in vivo determined by a balance of glucose absorption via the gut, production primarily by the liver, and utilization by both insulin-sensitive and insulin-insensitive tissues. Blood and plasma fasting glucose levels are tightly regulated within a narrow physiologic range by a feedback mechanism that targets a particular fasting glucose set point for each individual. Within healthy, nondiabetic populations there is substantial variation in fasting glucose levels. Approximately one-third of this variation is genetic. Disruption of normal glucose homeostasis and substantial elevations of fasting glucose are hallmarks of type 2 diabetes (T2D) and typically result from sustained reduction in pancreatic beta-cell function and insulin secretion (summary by Chen et al., 2008 and Prokopenko et al., 2009). (612108)

MalaCards based summary : Fasting Plasma Glucose Level Quantitative Trait Locus 1, also known as fasting plasma glucose level qtl 1, is related to fasting plasma glucose level quantitative trait locus 2. An important gene associated with Fasting Plasma Glucose Level Quantitative Trait Locus 1 is FGQTL1 (Fasting Plasma Glucose Level QTL 1). Affiliated tissues include liver.

Related Diseases for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Diseases in the Fasting Plasma Glucose Level Quantitative Trait Locus 5 family:

Fasting Plasma Glucose Level Quantitative Trait Locus 1 Fasting Plasma Glucose Level Quantitative Trait Locus 2
Fasting Plasma Glucose Level Quantitative Trait Locus 3 Fasting Plasma Glucose Level Quantitative Trait Locus 6
Fasting Plasma Glucose Level Quantitative Trait Locus 4

Diseases related to Fasting Plasma Glucose Level Quantitative Trait Locus 1 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 fasting plasma glucose level quantitative trait locus 2 11.0

Symptoms & Phenotypes for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Clinical features from OMIM:

612108

Drugs & Therapeutics for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Search Clinical Trials , NIH Clinical Center for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Genetic Tests for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Genetic tests related to Fasting Plasma Glucose Level Quantitative Trait Locus 1:

# Genetic test Affiliating Genes
1 Fasting Plasma Glucose Level Quantitative Trait Locus 1 29

Anatomical Context for Fasting Plasma Glucose Level Quantitative Trait Locus 1

MalaCards organs/tissues related to Fasting Plasma Glucose Level Quantitative Trait Locus 1:

41
Liver

Publications for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Variations for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Expression for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Search GEO for disease gene expression data for Fasting Plasma Glucose Level Quantitative Trait Locus 1.

Pathways for Fasting Plasma Glucose Level Quantitative Trait Locus 1

GO Terms for Fasting Plasma Glucose Level Quantitative Trait Locus 1

Sources for Fasting Plasma Glucose Level Quantitative Trait Locus 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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