MCID: FML031
MIFTS: 32

Female Stress Incontinence

Categories: Nephrological diseases

Aliases & Classifications for Female Stress Incontinence

MalaCards integrated aliases for Female Stress Incontinence:

Name: Female Stress Incontinence 12 15 37 71
Female Urinary Stress Incontinence 12
Stress Incontinence - Female 12

Classifications:



External Ids:

Disease Ontology 12 DOID:724
ICD9CM 34 625.6
NCIt 49 C35042
SNOMED-CT 67 60241006
UMLS 71 C0038437

Summaries for Female Stress Incontinence

MalaCards based summary : Female Stress Incontinence, also known as female urinary stress incontinence, is related to acute cystitis and constipation, and has symptoms including pain and other symptoms associated with female genital organs, mittelschmerz and unspecified symptom associated with female genital organs. An important gene associated with Female Stress Incontinence is MEOX2 (Mesenchyme Homeobox 2). The drugs Silicon and Sulfamethazine have been mentioned in the context of this disorder. Affiliated tissues include testes and bone, and related phenotypes are Decreased homologous recombination repair frequency and Decreased homologous recombination repair frequency

Related Diseases for Female Stress Incontinence

Graphical network of the top 20 diseases related to Female Stress Incontinence:



Diseases related to Female Stress Incontinence

Symptoms & Phenotypes for Female Stress Incontinence

UMLS symptoms related to Female Stress Incontinence:


pain and other symptoms associated with female genital organs, mittelschmerz, unspecified symptom associated with female genital organs, other specified symptoms associated with female genital organs, female genital pain and other symptoms

GenomeRNAi Phenotypes related to Female Stress Incontinence according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased homologous recombination repair frequency GR00151-A-1 8.92 MEOX2 SEM1
2 Decreased homologous recombination repair frequency GR00151-A-2 8.92 SEM1
3 Decreased homologous recombination repair frequency GR00236-A-3 8.92 SEM1

MGI Mouse Phenotypes related to Female Stress Incontinence:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 taste/olfaction MP:0005394 8.62 MEOX2 SLC6A1

Drugs & Therapeutics for Female Stress Incontinence

Drugs for Female Stress Incontinence (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Silicon Approved, Investigational 7440-21-3 4082203
2
Sulfamethazine Approved, Investigational, Vet_approved 57-68-1 5327
3
Methotrexate Approved 1959-05-2, 59-05-2 126941
4
leucovorin Approved 58-05-9 6006 143
5
Etoposide Approved 33419-42-0 36462
6
Cytarabine Approved, Experimental, Investigational 147-94-4, 65-46-3 6253
7
Levofloxacin Approved, Investigational 100986-85-4 149096
8
Nitrofurantoin Approved, Vet_approved 67-20-9 5353830
9
Ofloxacin Approved 82419-36-1 4583
10
Trimethoprim Approved, Vet_approved 738-70-5 5578
11
Sulfamethoxazole Approved 723-46-6 5329
12
Folic acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
13 Immunologic Factors
14 Folic Acid Antagonists
15 Anti-Infective Agents
16 Vitamin B Complex
17 Vitamin B9
18 Antiviral Agents
19 Antirheumatic Agents
20 Topoisomerase Inhibitors
21 Dermatologic Agents
22 Folate
23 Immunosuppressive Agents
24 Antimetabolites
25 Etoposide phosphate
26 Antibiotics, Antitubercular
27 Anti-Bacterial Agents
28 Trimethoprim, Sulfamethoxazole Drug Combination
29 Anesthetics

Interventional clinical trials:

(show all 29)
# Name Status NCT ID Phase Drugs
1 Randomized Controlled Study Comparing Two Types of Suburethral Slings for the Surgical Treatment of Female Stress Incontinence : TVT and TVT-O. Unknown status NCT00135616 Phase 4
2 Comparative Study of TVTO™ X TVTS ™ for Treatment of Stress Urinary Incontinence Completed NCT01095159 Phase 4
3 A Comparison Among Three Single-incision Devices for the Treatment of Female Urinary Genuine Stress Incontinence: a Randomized Controlled Study. Completed NCT00751088 Phase 4
4 A Comparison Between Laparoscopic Burch Colposuspension and Transobturatory Tape (TOT) for the Treatment of Female Urinary Stress Incontinence Withdrawn NCT00573703 Phase 4
5 A Randomized, Prospective, Multicenter Trial Comparing TVT With TVT-O Procedures in Treatment of Female Primary Urinary Stress Incontinence Unknown status NCT00379314 Phase 3
6 Is There Any Value of Concomitant Repair of Asymptomatic Grade II Anterior Vaginal Wall Prolapse During Mid Urethral Sling Surgery for Stress Urinary Incontinence ? Completed NCT03296748 Phase 2, Phase 3
7 Surgeon Tailored Hybrid Autologus Rectus Sheath Fascia Versus Midurethral Transobturator Tension Free Vaginal Tape For Treatment Of Stress Urinary Incontinence Not yet recruiting NCT03473041 Phase 3
8 Feasibility of Comparing Two Surgical Treatment of Female Urodynamic Stress Incontinence (SITOT) Completed NCT01230450 Phase 1
9 Lyrette: Renewing Continence Objective and Subjective Efficacy Study Unknown status NCT01455779
10 A Comparison of Continence Pessary to a Disposable Intravaginal Device in the Management of Stress Urinary Incontinence: A Randomized Controlled Trial Unknown status NCT03174431
11 TVT-ABBREVO Versus SERASIS for the Treatment of Female Urinary Stress Incontinence: 1 Year Outcomes of a Comparative Study With 2 Trans-obturator Sub Mid Urethral Slings Unknown status NCT02867748
12 Randomized, Crossover Feasibility Study of a Device to Prevent Female Urinary Stress Incontinence Completed NCT03010800
13 PROSPECTIVE RANDOMIZED STUDY COMPARING TVT AND TOT IN FEMALE STRESS URINARY INCONTINENCE WITH NO INTRINSIC SPHINCTER DEFICIENCY Completed NCT01903590
14 Intravaginal Laser Treatment of Mild and Moderate Stress Incontinence Completed NCT03267719
15 EFFECT OF A PROTOCOL Electrostimulation for Urinary Incontinence and Its Influence on WOMEN 'S QUALITY OF LIFE Completed NCT03682926
16 Incorporation of Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing: a Randomized Controlled Trial Completed NCT03625843
17 A Comparison of the Efficacy of Electrical Pudendal Nerve Stimulation to Pelvic Floor Muscle Training With Transvaginal Electrical Stimulation in Treating Female Stress Incontinence Completed NCT01763762
18 Posture Correction in Abdominopelvic Training in Women With Stress Urinary Incontinence Completed NCT03727945
19 The Effectiveness of a Care Protocol Developed Using the Star Model on Female Patients With Stress Incontinence: A Randomized Controlled Trial Completed NCT03866356
20 Incidence of Symptomatic and Asymptomatic Bacteriuria After Urodynamic Study With or Without Antibiotic Prophylaxis in Women With Urinary Incontinence Completed NCT03106103
21 Evaluation of the Effectiveness and Safety of the Midurethral Synthetic Tape With Tension Control Mechanism and Midurethral Tension Free Tape Recruiting NCT04101279
22 A Randomized Controlled Trial of a Group-Based Therapeutic Yoga Intervention for Urinary Incontinence in Ambulatory Older Women Recruiting NCT03672461
23 Evaluation of Role of Transperineal US in Differentiating Degrees of Genuine Stress Incontinence in Females Diagnosed by Urodynamics Recruiting NCT03397368
24 Vaginal Elasticity Assessment Before and After the Affect of Surgical Repair for Urinary Stress Incontinence (USI) on Vaginal Elasticity as Measured by Vaginal Tactile Imaging. Recruiting NCT03301818
25 Prospective Randomized Trial of Altis Minisling With the TVTO Transobturator Tape Procedure for the Management of Genuine Stress Urinaty Incontinence in Women Recruiting NCT03515109
26 Vaginal CO2 Laser for Stress Incontinence: A Randomized Controlled Trial Recruiting NCT04136652
27 Randomised, Sham Controlled Trial of Fotona Smooth Erbium Yag Laser In the Treatment of Stress Urinary Incontinence Not yet recruiting NCT03996070
28 Development and Evaluation of a New Diagnostic Test in Female Urinary Stress Incontinence Terminated NCT01563653
29 Collection of Long Term Patient Outcomes Data Following Implantation of AMS Surgical Devices Terminated NCT01673360

Search NIH Clinical Center for Female Stress Incontinence

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Female Stress Incontinence cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Female Stress Incontinence:
ICES13, autologous myoblasts for stress urinary incontinence
AMDC, autologous muscle-derived cells for urinary incontinence
Embryonic/Adult Cultured Cells Related to Female Stress Incontinence:
Autologous muscle-derived cells PMIDs: 23260547
Muscle-derived myoblasts

Genetic Tests for Female Stress Incontinence

Anatomical Context for Female Stress Incontinence

MalaCards organs/tissues related to Female Stress Incontinence:

40
Testes, Bone

Publications for Female Stress Incontinence

Articles related to Female Stress Incontinence:

(show top 50) (show all 219)
# Title Authors PMID Year
1
Position of the Ibero-American Society of Neurourology and Urogynecology in relation to the use of synthetic suburethral meshes for the surgical treatment of female stress incontinence. 61
31588610 2020
2
Biomarkers Implicated in Lower Urinary Tract Symptoms: Systematic Review and Pathway Analyses. 61
30925127 2019
3
[Ins and outs in the surgical treatment of female stress urinary incontinence]. 61
31111191 2019
4
Study design and outcomes measures: The influence of composite endpoints and other design variables on outcomes in a study of a novel device for stress urinary incontinence. 61
30203494 2018
5
The use of polyacrylamide hydrogel in the setting of failed female stress incontinence surgery. 61
29319483 2018
6
[Female stress incontinence: aspects of pathogenesis and functional anatomy]. 61
29390217 2018
7
[Implants for genital prolapse : Contra mesh surgery]. 61
29119201 2017
8
Is the adjustable TVA mesh effective for the long-term treatment of female stress incontinence? 61
27496772 2017
9
Holmium:YAG Laser Ablation for the Management of Lower Urinary Tract Foreign Bodies Following Incontinence Surgery: A Case Series and Systematic Review. 61
27604964 2016
10
Impact of urethral catheterization on uroflow during pressure-flow study. 61
27565744 2016
11
Definition of Success after Surgery for Female Stress Incontinence or Voiding Dysfunction: An Attempt at Standardization. 61
28723368 2016
12
Efficacy of Electrical Pudendal Nerve Stimulation in Treating Female Stress Incontinence. 61
26921645 2016
13
Trends in reoperation for female stress urinary incontinence: A nationwide study. 61
25067811 2015
14
Adjustable vs. ordinary transobturator tape for female stress incontinence. Is there a difference? 61
26413335 2015
15
Re: Efficacy and safety of polyacrylamide hydrogel for the treatment of female stress incontinence: a randomized, prospective, multicenter North American study. 61
25481730 2015
16
Efficacy and safety of polyacrylamide hydrogel for the treatment of female stress incontinence: a randomized, prospective, multicenter North American study. 61
24704117 2014
17
The first Iraqi experience with the rectus fascia sling and transobturator tape for female stress incontinence: A randomised trial. 61
26019950 2014
18
[Complication management in prolapse and incontinence surgery]. 61
25023238 2014
19
Long-term follow-up after urethral injection with polyacrylamide hydrogel for female stress incontinence. 61
24372312 2014
20
Is antibiotic prophylaxis necessary before midurethral sling procedures for female stress incontinence? A decision analysis. 61
23903818 2014
21
The TRT Female Remeex System ® for recurrent female stress urinary incontinence: a 5-year follow-up study. 61
23654323 2013
22
Cough Test during Tension-Free Vaginal Tape Procedure in Preventing Postoperative Urinary Retention. 61
23653639 2013
23
Comparison of two inside-out transobturator suburethral sling techniques for stress incontinence: early postoperative thigh pain and 3-year outcomes. 61
22882761 2012
24
[Female stress incontinence treatment: urethral slings]. 61
23101961 2012
25
Simultaneous perineal ultrasound and vaginal pressure measurement prove the action of electrical pudendal nerve stimulation in treating female stress incontinence. 61
22417077 2012
26
Treating stress urinary incontinence in female patients with neuropathic bladder: the value of the autologous fascia rectus sling. 61
22821050 2012
27
The autologous fascia pubovaginal sling for complicated female stress incontinence. 61
22396366 2012
28
Hypothesis - a congenitally lax pubourethral ligament may be a contributing cause of vesicoureteral reflux. 61
24578927 2012
29
Outlet obstruction after sling surgery. 61
22085122 2011
30
Efficacy and preoperative prognostic factors of autologous fascia rectus sling for treatment of female stress urinary incontinence. 61
22054371 2011
31
Ureteral erosion of a transvaginal tape. 61
21672492 2011
32
Are urodynamics needed before surgery for straightforward female stress incontinence? 61
20965521 2010
33
Are urodynamics needed before surgery for straightforward female stress incontinence? 61
20961583 2010
34
Update of AUA guideline on the surgical management of female stress urinary incontinence. 61
20303102 2010
35
[Clinical and urodynamic repercussions after treatment of female stress incontinence with transobturator suburethral tape]. 61
20471582 2010
36
Transobturator tape for female stress incontinence: follow-up after 24 months. 61
20165575 2010
37
[Guidelines for the surgical treatment of female urinary stress incontinence in women using the suburethral sling]. 61
20403563 2010
38
Correction of erosion after suburethral sling insertion for stress incontinence: results and related sexual function. 61
18684552 2009
39
Urodynamics in the management of female stress incontinence--which test and when? 61
18520755 2008
40
Transobturator tape in the management of female stress incontinence: clinical outcomes at medium term follow-up. 61
18480630 2008
41
Trans-obturator suburethral tape for female stress incontinence: a cohort of 254 women with 1-year to 2-year follow-up. 61
18231894 2008
42
Pelvic floor reconstruction in female exstrophic complex patients: different results from males? 61
17582675 2007
43
Autologous myoblasts and fibroblasts for female stress incontinence: a 1-year follow-up in 123 patients. 61
17760890 2007
44
[Trans obturator tape (TOT) for female stress incontinence. Experience with three years follow-up in 200 patients]. 61
18314653 2007
45
Transobturator surgery for female stress incontinence: a comparative anatomical study of outside-in vs inside-out techniques. 61
17868425 2007
46
A safety and quality of life analysis of intravaginal slingplasty in female stress incontinence: a prospective, open label, multicenter, and observational study. 61
17333435 2007
47
MRI urethrovesical junction mobility is associated with global pelvic floor laxity in female stress incontinence. 61
17851825 2007
48
Experimental evaluation of suture support in bladder-neck suspension for the treatment of female stress urinary incontinence. 61
17867957 2007
49
What's new in slings: an update on midurethral slings. 61
17558266 2007
50
Adductor brevis myositis following transobturator tape procedure: a case report and review of the literature. 61
17577593 2007

Variations for Female Stress Incontinence

Expression for Female Stress Incontinence

Search GEO for disease gene expression data for Female Stress Incontinence.

Pathways for Female Stress Incontinence

GO Terms for Female Stress Incontinence

Sources for Female Stress Incontinence

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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