MCID: FMR003
MIFTS: 39

Femoral Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Femoral Neuropathy

MalaCards integrated aliases for Femoral Neuropathy:

Name: Femoral Neuropathy 12 44 15 73
Femoral Nerve Dysfunction 12
Femoral Nerve Lesions 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4196
ICD10 33 G57.2 G57.20
MeSH 44 D020428
NCIt 50 C27595
SNOMED-CT 68 25690000
UMLS 73 C0751931

Summaries for Femoral Neuropathy

Disease Ontology : 12 A mononeuropathy that is characterized by a loss of movement or sensation in parts of the legs due to damage to the femoral nerve.

MalaCards based summary : Femoral Neuropathy, also known as femoral nerve dysfunction, is related to hemophilia and von willebrand's disease. An important gene associated with Femoral Neuropathy is VLDLR (Very Low Density Lipoprotein Receptor), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Anesthetics and Anesthetics, Local have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and kidney.

Wikipedia : 76 The femoral nerve is a nerve in the thigh that supplies skin on the upper thigh and inner leg, and the... more...

Related Diseases for Femoral Neuropathy

Diseases related to Femoral Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 hemophilia 29.8 F2 F3
2 von willebrand's disease 29.6 F2 F3
3 neuropathy 10.9
4 conjugate gaze palsy 10.2 F3 PLG
5 hemorrhagic fever 10.2 F2 F3
6 dysbaric osteonecrosis 10.2 F3 PLG
7 prothrombin deficiency 10.2 F2 F3
8 fournier gangrene 10.2 F2 F3
9 cerebral sinovenous thrombosis 10.2 F2 F3
10 qualitative platelet defect 10.1 F2 F3
11 sagittal sinus thrombosis 10.1 F2 F3
12 vertebral artery occlusion 10.1 F3 PLG
13 alcohol-related birth defect 10.1 F2 F3
14 hantavirus pulmonary syndrome 10.1 F2 F3
15 von willebrand disease, type 1 10.1 F2 F3
16 lemierre's syndrome 10.1 F3 PLG
17 marantic endocarditis 10.1 F2 F3
18 vascular hemostatic disease 10.1 F2 F3
19 intracranial thrombosis 10.1 F3 PLG
20 splenic disease 10.1 F2 F3
21 alpha-2-plasmin inhibitor deficiency 10.1 F2 PLG
22 intracranial embolism 10.1 F2 PLG
23 purpura fulminans 10.1 F2 F3
24 hepatic infarction 10.1 F2 F3
25 intermediate coronary syndrome 10.1 F3 PLG
26 peripheral vertigo 10.1 F2 F3
27 inherited blood coagulation disease 10.1 F2 F3
28 livedoid vasculitis 10.1 F2 PLG
29 blood protein disease 10.1 F2 F3
30 retinal vascular occlusion 10.1 F2 PLG
31 anterior spinal artery syndrome 10.1 F2 PLG
32 branch retinal artery occlusion 10.1 F2 F3
33 tuberculous empyema 10.1 CEACAM5 PLG
34 hepatic veno-occlusive disease 10.1 F3 PLG
35 analbuminemia 10.1 F2 F3
36 factor xi deficiency 10.1 F2 F3
37 squamous cell papilloma 10.1 F2 F3
38 protein s deficiency 10.1 F2 F3
39 orbital cyst 10.1 CEACAM5 F2
40 eccrine adenocarcinoma 10.1 CEACAM5 F2
41 thrombasthenia 10.1 F2 F3
42 factor vii deficiency 10.1 F2 F3
43 hemophilia b 10.1 F2 F3
44 intracranial hypertension 10.1 F2 F3
45 factor x deficiency 10.1 F2 F3
46 afibrinogenemia 10.1 F2 F3
47 placental insufficiency 10.0 F2 F3
48 afibrinogenemia, congenital 10.0 F2 F3
49 cerebral falx meningioma 10.0 F2 F3 PLG
50 leech infestation 10.0 F2 F3 PLG

Graphical network of the top 20 diseases related to Femoral Neuropathy:



Diseases related to Femoral Neuropathy

Symptoms & Phenotypes for Femoral Neuropathy

Drugs & Therapeutics for Femoral Neuropathy

Drugs for Femoral Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics Phase 1,Not Applicable
2 Anesthetics, Local Phase 1
3
Morphine Approved, Investigational Not Applicable 57-27-2 5288826
4
Ropivacaine Approved Not Applicable 84057-95-4 175805 71273
5
Ibuprofen Approved Not Applicable 15687-27-1 3672
6 Analgesics Not Applicable
7 Central Nervous System Depressants Not Applicable
8 Narcotics Not Applicable
9 Peripheral Nervous System Agents Not Applicable
10 Analgesics, Opioid Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Local Anaesthetic Following Hernia Repair Terminated NCT00471692 Phase 1 Ropivicaine
2 Femoral Nerve Block: Anatomical Insertion Point - A Prospective Randomised Double-Blind Controlled Trial Unknown status NCT00732706 Not Applicable
3 Femoral Neuropathy After Anterior Cruciate Ligament Reconstruction: Femoral Nerve Block vs Patient-controlled Analgesia (PCA) Completed NCT01321138 Not Applicable
4 The AbsorbaSeal Vascular Closure Device Trial Recruiting NCT03730571 Not Applicable
5 Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block Withdrawn NCT01334632 Not Applicable

Search NIH Clinical Center for Femoral Neuropathy

Cochrane evidence based reviews: femoral neuropathy

Genetic Tests for Femoral Neuropathy

Anatomical Context for Femoral Neuropathy

MalaCards organs/tissues related to Femoral Neuropathy:

41
Skin, Bone, Kidney, Brain

Publications for Femoral Neuropathy

Articles related to Femoral Neuropathy:

(show top 50) (show all 194)
# Title Authors Year
1
Femoral Neuropathy Secondary to Autosomal Dominant Polycystic Kidney Disease: A Case Report. ( 29961749 )
2018
2
Femoral neuropathy following a psoas hitch vesicopexy. ( 30049676 )
2018
3
Femoral neuropathy following direct anterior total hip arthroplasty: an anatomic review and case series†. ( 30206472 )
2018
4
Femoral Neuropathy Following Transfemoral Neuroendovascular Procedures. An Analysis of a Prospective Registry. ( 30468262 )
2018
5
Bilateral Femoral Neuropathy Following Psoas Muscle Hematomas Caused by Enoxaparin Therapy. ( 28848224 )
2017
6
Femoral Neuropathy Following Spontaneous Retroperitoneal Hemorrhage After Cardiac Surgery: A Case Report. ( 28079661 )
2017
7
A Case of Idiopathic Femoral Neuropathy With Subsequent Quadriceps Atrophy. ( 28221309 )
2017
8
Compressive Femoral Neuropathy Associated with Iliopsoas Hematoma Complicating Hip Hemiarthroplasty: A Case Report. ( 29242785 )
2017
9
Poster 269 A Rare Case of Femoral Neuropathy Following Anterolateral Total Hip Arthroplasty. ( 27673026 )
2016
10
Sports induced femoral neuropathy: Review of literature. ( 27841202 )
2016
11
Ischemic-reperfusion of unilateral external iliac artery in rat: A new model for vasculitic femoral neuropathy. ( 27288016 )
2016
12
Bilateral Femoral Neuropathy After Transurethral Lithotomy in the Lithotomy Position: Report of a Case. ( 27224440 )
2016
13
A Rare Case of Femoral Neuropathy Associated with Ilio-Psoas Bursitis After 10 Years of Total Hip Arthroplasty. ( 26312109 )
2015
14
A Rare Case of Femoral Neuropathy Associated with Ilio-Psoas Bursitis After 10 Years of Total Hip Arthroplasty. ( 26587059 )
2015
15
Bilateral Iatrogenic Femoral Neuropathy. ( 26256661 )
2015
16
Femoral neuropathy caused by hyperlordotic positioning. ( 24554248 )
2014
17
Conservative treatment of femoral neuropathy following retroperitoneal hemorrhage: a case report and review of literature. ( 24686104 )
2014
18
Femoral neuropathy: a rare complication of retroperitoneal hematoma caused by cesarean section. ( 22941351 )
2013
19
Large psoas haematoma and femoral neuropathy in a patient with type 2B von Willebrand's disease. ( 23005922 )
2012
20
High-resolution 3-T MR neurography of femoral neuropathy. ( 22194473 )
2012
21
Bilateral femoral neuropathy after massive toxic ingestion in a suicide attempt. ( 22367832 )
2012
22
Femoral neuropathy and meralgia paresthetica secondary to an iliacus hematoma. ( 22639754 )
2012
23
Femoral neuropathy following total hip arthroplasty: review and management guidelines. ( 22696981 )
2012
24
Femoral Neuropathy due to Iliacus Muscle Hematoma in a Patient on Warfarin Therapy. ( 22396845 )
2012
25
Femoral neuropathy after vaginal surgery: a complication of the lithotomy position. ( 21281008 )
2011
26
Transient femoral neuropathy after knee ligament reconstruction and nerve stimulator-guided continuous femoral nerve block: a case series. ( 21831093 )
2011
27
Duloxetine contributing to a successful multimodal treatment program for peripheral femoral neuropathy and comorbid 'reactive depression' in an adolescent. ( 22184557 )
2011
28
Lumbar plexopathy caused by metastatic tumor, which was mistaken for postoperative femoral neuropathy. ( 22220245 )
2011
29
Acute femoral neuropathy following renal transplantation: a retrospective, multicenter study in China. ( 20620504 )
2010
30
Iatrogenic femoral neuropathy: two cases and literature update. ( 21386773 )
2010
31
Postpartum femoral neuropathy following spontaneous vaginal delivery. ( 20143990 )
2010
32
Acute femoral neuropathy: a rare complication after renal transplantation. ( 21168704 )
2010
33
Femoral neuropathy caused by compressive iliopsoas hydatid cyst: a case report and review of the literature. ( 20478731 )
2010
34
Ultrasound-guided placement of a permanent percutaneous femoral nerve stimulator leads for the treatment of intractable femoral neuropathy. ( 19668289 )
2009
35
Case report: femoral neuropathy secondary to total hip arthroplasty wear debris. ( 19452234 )
2009
36
Non-operative management of femoral neuropathy secondary to a traumatic iliacus haematoma in an adolescent. ( 18827251 )
2008
37
Iliopsoas bursitis-associated femoral neuropathy exacerbated after internal fixation of an intertrochanteric hip fracture in rheumatoid arthritis: a case report. ( 18421416 )
2008
38
Transient femoral neuropathy after abdominoplasty. ( 18948773 )
2008
39
The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. ( 19097010 )
2008
40
Iatrogenic femoral neuropathy following pelvic surgery: a rare and often overlooked complication--four case reports and literature review. ( 17939268 )
2007
41
Femoral neuropathy in a patient with rheumatoid arthritis. ( 17963353 )
2007
42
Compressive femoral neuropathy: a rare complication of anticoagulation. ( 17342281 )
2007
43
Femoral Neuropathy following Vaginal Hysterectomy. ( 27408062 )
2007
44
Bilateral femoral neuropathy associated with disseminated intravascular coagulopathy: a case report. ( 17042241 )
2006
45
Femoral neuropathy following retroperitoneal hemorrhage: case series and review of the literature. ( 16741653 )
2006
46
Femoral neuropathy in a dog with iliopsoas muscle injury. ( 16472299 )
2006
47
Epidural analgesia masked the diagnosis of femoral neuropathy following renal transplantation. ( 17037007 )
2006
48
Femoral neuropathy induced by a low-grade myofibroblastic sarcoma of the groin. ( 15981081 )
2005
49
Femoral neuropathy due to patellar dislocation in a theatrical and jazz dancer: a case report. ( 15954069 )
2005
50
Bilateral femoral neuropathy complicating rhabdomyolysis and acute renal failure. ( 19078767 )
2005

Variations for Femoral Neuropathy

Expression for Femoral Neuropathy

Search GEO for disease gene expression data for Femoral Neuropathy.

Pathways for Femoral Neuropathy

GO Terms for Femoral Neuropathy

Cellular components related to Femoral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.92 AXL CEACAM5 F3 PLG

Biological processes related to Femoral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.43 F2 F3 PLG
2 fibrinolysis GO:0042730 9.16 F2 PLG
3 negative regulation of fibrinolysis GO:0051918 8.96 F2 PLG
4 hemostasis GO:0007599 8.8 F2 F3 PLG

Molecular functions related to Femoral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.13 F2 F3 PLG
2 apolipoprotein binding GO:0034185 8.62 PLG VLDLR

Sources for Femoral Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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