MCID: FMR003
MIFTS: 39

Femoral Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Femoral Neuropathy

MalaCards integrated aliases for Femoral Neuropathy:

Name: Femoral Neuropathy 12 44 15 73
Femoral Nerve Dysfunction 12
Femoral Nerve Lesions 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4196
ICD10 33 G57.2 G57.20
MeSH 44 D020428
NCIt 50 C27595
SNOMED-CT 68 193146000 25690000
UMLS 73 C0751931

Summaries for Femoral Neuropathy

Disease Ontology : 12 A mononeuropathy that is characterized by a loss of movement or sensation in parts of the legs due to damage to the femoral nerve.

MalaCards based summary : Femoral Neuropathy, also known as femoral nerve dysfunction, is related to hemophilia and neuropathy. An important gene associated with Femoral Neuropathy is VLDLR (Very Low Density Lipoprotein Receptor), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Anesthetics and Anesthetics, Local have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and kidney.

Wikipedia : 76 The femoral nerve is a nerve in the thigh that supplies skin on the upper thigh and inner leg, and the... more...

Related Diseases for Femoral Neuropathy

Diseases related to Femoral Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 107)
# Related Disease Score Top Affiliating Genes
1 hemophilia 30.1 F2 F3
2 neuropathy 10.8
3 conjugate gaze palsy 10.7 F3 PLG
4 fournier gangrene 10.6 F2 F3
5 cerebral sinovenous thrombosis 10.6 F2 F3
6 qualitative platelet defect 10.6 F2 F3
7 dysbaric osteonecrosis 10.6 F3 PLG
8 sagittal sinus thrombosis 10.6 F2 F3
9 von willebrand disease, type 1 10.6 F2 F3
10 alcohol-related birth defect 10.6 F2 F3
11 alpha-2-plasmin inhibitor deficiency 10.6 F2 PLG
12 hantavirus pulmonary syndrome 10.5 F2 F3
13 partial motor epilepsy 10.5 F3 SMUG1
14 bone epithelioid hemangioma 10.5 F3 SMUG1
15 splenic disease 10.5 F2 F3
16 marantic endocarditis 10.5 F2 F3
17 histidine metabolism disease 10.5 CYP2B6 PLG
18 purpura fulminans 10.5 F2 F3
19 vertebral artery occlusion 10.5 F3 PLG
20 anterior spinal artery syndrome 10.5 F2 PLG
21 inherited blood coagulation disease 10.5 F2 F3
22 pulmonary artery leiomyosarcoma 10.5 PLG SMUG1
23 hepatic infarction 10.5 F2 F3
24 basilar artery occlusion 10.5 F2 PLG
25 prothrombin deficiency 10.5 F2 F3
26 peripheral vertigo 10.5 F2 F3
27 retinal vascular occlusion 10.5 F2 PLG
28 intermediate coronary syndrome 10.5 F3 PLG
29 hemorrhagic fever 10.4 F2 F3
30 hepatic tuberculosis 10.4 F2 SMUG1
31 endometrial small cell carcinoma 10.4 F2 SMUG1
32 branch retinal artery occlusion 10.4 F2 F3
33 tuberculous empyema 10.4 CEACAM5 PLG
34 analbuminemia 10.4 F2 F3
35 squamous cell papilloma 10.4 F2 F3
36 baastrup's syndrome 10.4 RPL34 SMUG1
37 orbital cyst 10.4 CEACAM5 F2
38 factor xi deficiency 10.3 F2 F3
39 liver lymphoma 10.3 CEACAM5 SMUG1
40 splenic tuberculosis 10.3 CEACAM5 SMUG1
41 gallbladder squamous cell carcinoma 10.3 CEACAM5 SMUG1
42 protein s deficiency 10.3 F2 F3
43 malignant spiradenoma 10.3 CEACAM5 SMUG1
44 hepatic veno-occlusive disease 10.3 F3 PLG
45 tolosa-hunt syndrome 10.3 CEACAM5 SMUG1
46 gastric signet ring cell adenocarcinoma 10.3 CEACAM5 SMUG1
47 severe hemophilia a 10.3 F2 F3
48 pericardial tuberculosis 10.3 CEACAM5 SMUG1
49 peliosis hepatis 10.3 F2 SMUG1
50 descending colon cancer 10.3 CEACAM5 SMUG1

Graphical network of the top 20 diseases related to Femoral Neuropathy:



Diseases related to Femoral Neuropathy

Symptoms & Phenotypes for Femoral Neuropathy

Drugs & Therapeutics for Femoral Neuropathy

Drugs for Femoral Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics Phase 1,Not Applicable
2 Anesthetics, Local Phase 1
3
Morphine Approved, Investigational Not Applicable 57-27-2 5288826
4
Ropivacaine Approved Not Applicable 84057-95-4 71273 175805
5
Ibuprofen Approved Not Applicable 15687-27-1 3672
6 Analgesics Not Applicable
7 Central Nervous System Depressants Not Applicable
8 Narcotics Not Applicable
9 Analgesics, Opioid Not Applicable
10 Peripheral Nervous System Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Local Anaesthetic Following Hernia Repair Terminated NCT00471692 Phase 1 Ropivicaine
2 Femoral Nerve Block: Anatomical Insertion Point - A Prospective Randomised Double-Blind Controlled Trial Unknown status NCT00732706 Not Applicable
3 Femoral Neuropathy After Anterior Cruciate Ligament Reconstruction: Femoral Nerve Block vs Patient-controlled Analgesia (PCA) Completed NCT01321138 Not Applicable
4 Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block Withdrawn NCT01334632 Not Applicable

Search NIH Clinical Center for Femoral Neuropathy

Cochrane evidence based reviews: femoral neuropathy

Genetic Tests for Femoral Neuropathy

Anatomical Context for Femoral Neuropathy

MalaCards organs/tissues related to Femoral Neuropathy:

41
Skin, Bone, Kidney, Brain

Publications for Femoral Neuropathy

Articles related to Femoral Neuropathy:

(show top 50) (show all 184)
# Title Authors Year
1
Femoral Neuropathy Secondary to Autosomal Dominant Polycystic Kidney Disease: A Case Report. ( 29961749 )
2018
2
Bilateral Femoral Neuropathy Following Psoas Muscle Hematomas Caused by Enoxaparin Therapy. ( 28848224 )
2017
3
Femoral Neuropathy Following Spontaneous Retroperitoneal Hemorrhage After Cardiac Surgery: A Case Report. ( 28079661 )
2017
4
A Case of Idiopathic Femoral Neuropathy With Subsequent Quadriceps Atrophy. ( 28221309 )
2017
5
Compressive Femoral Neuropathy Associated with Iliopsoas Hematoma Complicating Hip Hemiarthroplasty: A Case Report. ( 29242785 )
2017
6
Poster 269 A Rare Case of Femoral Neuropathy Following Anterolateral Total Hip Arthroplasty. ( 27673026 )
2016
7
Sports induced femoral neuropathy: Review of literature. ( 27841202 )
2016
8
Ischemic-reperfusion of unilateral external iliac artery in rat: A new model for vasculitic femoral neuropathy. ( 27288016 )
2016
9
Bilateral Femoral Neuropathy After Transurethral Lithotomy in the Lithotomy Position: Report of a Case. ( 27224440 )
2016
10
A Rare Case of Femoral Neuropathy Associated with Ilio-Psoas Bursitis After 10 Years of Total Hip Arthroplasty. ( 26312109 )
2015
11
A Rare Case of Femoral Neuropathy Associated with Ilio-Psoas Bursitis After 10 Years of Total Hip Arthroplasty. ( 26587059 )
2015
12
Bilateral Iatrogenic Femoral Neuropathy. ( 26256661 )
2015
13
Femoral neuropathy caused by hyperlordotic positioning. ( 24554248 )
2014
14
Conservative treatment of femoral neuropathy following retroperitoneal hemorrhage: a case report and review of literature. ( 24686104 )
2014
15
Femoral neuropathy: a rare complication of retroperitoneal hematoma caused by cesarean section. ( 22941351 )
2013
16
Large psoas haematoma and femoral neuropathy in a patient with type 2B von Willebrand's disease. ( 23005922 )
2012
17
High-resolution 3-T MR neurography of femoral neuropathy. ( 22194473 )
2012
18
Bilateral femoral neuropathy after massive toxic ingestion in a suicide attempt. ( 22367832 )
2012
19
Femoral neuropathy and meralgia paresthetica secondary to an iliacus hematoma. ( 22639754 )
2012
20
Femoral neuropathy following total hip arthroplasty: review and management guidelines. ( 22696981 )
2012
21
Femoral Neuropathy due to Iliacus Muscle Hematoma in a Patient on Warfarin Therapy. ( 22396845 )
2012
22
Femoral neuropathy after vaginal surgery: a complication of the lithotomy position. ( 21281008 )
2011
23
Transient femoral neuropathy after knee ligament reconstruction and nerve stimulator-guided continuous femoral nerve block: a case series. ( 21831093 )
2011
24
Duloxetine contributing to a successful multimodal treatment program for peripheral femoral neuropathy and comorbid 'reactive depression' in an adolescent. ( 22184557 )
2011
25
Lumbar plexopathy caused by metastatic tumor, which was mistaken for postoperative femoral neuropathy. ( 22220245 )
2011
26
Acute femoral neuropathy following renal transplantation: a retrospective, multicenter study in China. ( 20620504 )
2010
27
Iatrogenic femoral neuropathy: two cases and literature update. ( 21386773 )
2010
28
Postpartum femoral neuropathy following spontaneous vaginal delivery. ( 20143990 )
2010
29
Acute femoral neuropathy: a rare complication after renal transplantation. ( 21168704 )
2010
30
Femoral neuropathy caused by compressive iliopsoas hydatid cyst: a case report and review of the literature. ( 20478731 )
2010
31
Ultrasound-guided placement of a permanent percutaneous femoral nerve stimulator leads for the treatment of intractable femoral neuropathy. ( 19668289 )
2009
32
Case report: femoral neuropathy secondary to total hip arthroplasty wear debris. ( 19452234 )
2009
33
Non-operative management of femoral neuropathy secondary to a traumatic iliacus haematoma in an adolescent. ( 18827251 )
2008
34
Iliopsoas bursitis-associated femoral neuropathy exacerbated after internal fixation of an intertrochanteric hip fracture in rheumatoid arthritis: a case report. ( 18421416 )
2008
35
Transient femoral neuropathy after abdominoplasty. ( 18948773 )
2008
36
The treatment of femoral neuropathy due to pseudotumour caused by metal-on-metal resurfacing arthroplasty. ( 19097010 )
2008
37
Iatrogenic femoral neuropathy following pelvic surgery: a rare and often overlooked complication--four case reports and literature review. ( 17939268 )
2007
38
Femoral neuropathy in a patient with rheumatoid arthritis. ( 17963353 )
2007
39
Compressive femoral neuropathy: a rare complication of anticoagulation. ( 17342281 )
2007
40
Bilateral femoral neuropathy associated with disseminated intravascular coagulopathy: a case report. ( 17042241 )
2006
41
Femoral neuropathy following retroperitoneal hemorrhage: case series and review of the literature. ( 16741653 )
2006
42
Femoral neuropathy in a dog with iliopsoas muscle injury. ( 16472299 )
2006
43
Epidural analgesia masked the diagnosis of femoral neuropathy following renal transplantation. ( 17037007 )
2006
44
Femoral neuropathy induced by a low-grade myofibroblastic sarcoma of the groin. ( 15981081 )
2005
45
Femoral neuropathy due to patellar dislocation in a theatrical and jazz dancer: a case report. ( 15954069 )
2005
46
Bilateral femoral neuropathy complicating rhabdomyolysis and acute renal failure. ( 19078767 )
2005
47
Transient femoral neuropathy after harvest of bone from the iliac crest. ( 15544891 )
2004
48
The role of knee immobilizers in cancer patients with femoral neuropathy. ( 14966718 )
2004
49
Femoral neuropathy after pelvic surgery. ( 15779491 )
2004
50
Acute femoral neuropathy secondary to an iliacus muscle hematoma. ( 12686414 )
2003

Variations for Femoral Neuropathy

Expression for Femoral Neuropathy

Search GEO for disease gene expression data for Femoral Neuropathy.

Pathways for Femoral Neuropathy

GO Terms for Femoral Neuropathy

Biological processes related to Femoral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.43 F2 F3 PLG
2 fibrinolysis GO:0042730 9.16 F2 PLG
3 negative regulation of fibrinolysis GO:0051918 8.96 F2 PLG
4 hemostasis GO:0007599 8.8 F2 F3 PLG

Molecular functions related to Femoral Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.13 F2 F3 PLG
2 apolipoprotein binding GO:0034185 8.62 PLG VLDLR

Sources for Femoral Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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