MCID: FTL005
MIFTS: 31

Fetal Adenoma

Categories: Cancer diseases, Endocrine diseases, Fetal diseases

Aliases & Classifications for Fetal Adenoma

MalaCards integrated aliases for Fetal Adenoma:

Name: Fetal Adenoma 12 15
Microfollicular Adenoma 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:8102
NCIt 50 C4160
SNOMED-CT 68 30301008
UMLS 73 C0334328

Summaries for Fetal Adenoma

MalaCards based summary : Fetal Adenoma, also known as microfollicular adenoma, is related to mucoepidermoid thyroid carcinoma and suppurative thyroiditis. An important gene associated with Fetal Adenoma is TG (Thyroglobulin), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Long-term potentiation. Affiliated tissues include thyroid, lung and skin, and related phenotypes are endocrine/exocrine gland and neoplasm

Related Diseases for Fetal Adenoma

Diseases related to Fetal Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 75)
# Related Disease Score Top Affiliating Genes
1 mucoepidermoid thyroid carcinoma 10.3 CALCA TG
2 suppurative thyroiditis 10.3 CALCA TG
3 thyroid sarcoma 10.3 CALCA TG
4 struma ovarii 10.3 NKX2-1 TG
5 acute thyroiditis 10.2 CALCA TG
6 giant congenital nevus 10.2 HRAS NRAS
7 ovarian germ cell cancer 10.2 NKX2-1 TG
8 athyreosis 10.2 NKX2-1 TG
9 schimmelpenning-feuerstein-mims syndrome 10.2 HRAS NRAS
10 hypoadrenalism 10.2 CALCA TG
11 ovarian melanoma 10.2 HRAS NRAS
12 chromosome 14q11-q22 deletion syndrome 10.2 HRAS NKX2-1
13 amyloid tumor 10.2 CALCA TG
14 malignant conjunctival melanoma 10.2 HRAS NRAS
15 melanomatosis 10.2 HRAS NRAS
16 marcus gunn phenomenon 10.2 HRAS NRAS
17 papillary thymic adenocarcinoma 10.2 CD5 TG
18 nontoxic goiter 10.2 CALCA TG
19 nodular malignant melanoma 10.2 HRAS NRAS
20 secondary hypertrophic osteoarthropathy 10.2 CALCA HRAS
21 lung adenoid cystic carcinoma 10.2 HRAS NKX2-1
22 myelodysplastic myeloproliferative cancer 10.2 HRAS NRAS
23 lymphoepithelioma-like thymic carcinoma 10.2 CD5 TG
24 meningeal melanomatosis 10.2 HRAS NRAS
25 shrimp allergy 10.2 ACTB LGALS3
26 melanocytic nevus syndrome, congenital 10.1 HRAS NRAS
27 sigmoid neoplasm 10.1 CEACAM5 HRAS
28 benign struma ovarii 10.1 HRAS NRAS TG
29 pancreatic cystadenocarcinoma 10.1 CALCA CEACAM5
30 apocrine adenoma 10.1 CEACAM5 HRAS
31 clear cell adenoma 10.1 CEACAM5 TG
32 papillary thyroid microcarcinoma 10.1 CALCA NKX2-1 TG
33 acneiform dermatitis 10.1 HRAS NRAS
34 ovarian germ cell teratoma 10.1 NKX2-1 NRAS TG
35 ovarian cystic teratoma 10.1 CALCA NKX2-1 TG
36 crustacean allergy 10.1 ACTB LGALS3
37 aggressive digital papillary adenocarcinoma 10.1 CEACAM5 HRAS
38 nodular goiter 10.1 CALCA LGALS3 TG
39 vulvar melanoma 10.1 HRAS NRAS
40 mucinous bronchioloalveolar adenocarcinoma 10.1 LGALS3 NKX2-1
41 hashimoto thyroiditis 10.1 CALCA LGALS3 TG
42 rete testis adenocarcinoma 10.1 CEACAM5 NKX2-1
43 colloid adenoma 10.1 LGALS3 NKX2-1 TG
44 prostate squamous cell carcinoma 10.1 CEACAM5 HRAS
45 hypothyroidism, congenital, nongoitrous, 2 10.1 LGALS3 NKX2-1 TG
46 atypical follicular adenoma 10.1 CALCA CEACAM5 TG
47 thymus adenocarcinoma 10.1 CD5 CEACAM5
48 mucoepidermoid carcinoma 10.1 CALCA CEACAM5 TG
49 biliary papillomatosis 10.1 CEACAM5 HRAS
50 cell type benign neoplasm 10.1 CEACAM5 HRAS TG

Graphical network of the top 20 diseases related to Fetal Adenoma:



Diseases related to Fetal Adenoma

Symptoms & Phenotypes for Fetal Adenoma

MGI Mouse Phenotypes related to Fetal Adenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.5 ACTB HRAS NKX2-1 NR4A1 NR4A3 NRAS
2 neoplasm MP:0002006 9.17 ACTB HRAS LGALS3 NKX2-1 NR4A1 NR4A3

Drugs & Therapeutics for Fetal Adenoma

Search Clinical Trials , NIH Clinical Center for Fetal Adenoma

Genetic Tests for Fetal Adenoma

Anatomical Context for Fetal Adenoma

MalaCards organs/tissues related to Fetal Adenoma:

41
Thyroid, Lung, Skin, Liver, Ovary, Testis, Thymus

Publications for Fetal Adenoma

Articles related to Fetal Adenoma:

# Title Authors Year
1
Microfollicular adenoma of ectopic thyroid gland masquerading as salivary gland tumor - a diagnostic and therapeutic challenge: a case report. ( 25103611 )
2014
2
Involvement of the HMGI(Y) gene in a microfollicular adenoma of the thyroid. ( 10451711 )
1999
3
Lung carcinoma metastatic to microfollicular adenoma of the thyroid. A case report. ( 2239314 )
1990
4
Fetal adenoma of the thyroid. A common source for false-positive thallium-201/technetium-99m pertechnetate subtraction parathyroid scintigraphy. ( 2886243 )
1987
5
Fetal adenoma of the pigmented ciliary epithelium associated with persistent hyperplastic primary vitreous. ( 3785893 )
1986
6
Signet-ring cell microfollicular adenoma arising in a nodular ectopic thyroid. A case report. ( 3104557 )
1986
7
Reverse discordant behavior in microfollicular adenoma of thyroid. Case report. ( 2998673 )
1985
8
Mucin producing microfollicular adenoma of the thyroid. ( 3973051 )
1985
9
Signet-cell-simulating microfollicular adenoma of the thyroid. ( 6383090 )
1984

Variations for Fetal Adenoma

Expression for Fetal Adenoma

Search GEO for disease gene expression data for Fetal Adenoma.

Pathways for Fetal Adenoma

GO Terms for Fetal Adenoma

Biological processes related to Fetal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 thyroid gland development GO:0030878 9.16 NKX2-1 TG
2 regulation of type B pancreatic cell proliferation GO:0061469 8.96 NR4A1 NR4A3
3 cellular response to corticotropin-releasing hormone stimulus GO:0071376 8.62 NR4A1 NR4A3

Molecular functions related to Fetal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.26 ACTB NKX2-1 NR4A1 NR4A3
2 glucocorticoid receptor binding GO:0035259 8.62 NR4A1 NR4A3

Sources for Fetal Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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