MCID: FTL005
MIFTS: 31

Fetal Adenoma

Categories: Cancer diseases, Endocrine diseases, Fetal diseases

Aliases & Classifications for Fetal Adenoma

MalaCards integrated aliases for Fetal Adenoma:

Name: Fetal Adenoma 12 15
Microfollicular Adenoma 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:8102
NCIt 51 C4160
SNOMED-CT 69 30301008
UMLS 74 C0334328

Summaries for Fetal Adenoma

MalaCards based summary : Fetal Adenoma, also known as microfollicular adenoma, is related to mucoepidermoid thyroid carcinoma and struma ovarii. An important gene associated with Fetal Adenoma is TG (Thyroglobulin), and among its related pathways/superpathways are Long-term potentiation and Thyroid hormone signaling pathway. Affiliated tissues include thyroid, lung and breast, and related phenotypes are endocrine/exocrine gland and growth/size/body region

Related Diseases for Fetal Adenoma

Diseases related to Fetal Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 mucoepidermoid thyroid carcinoma 10.4 CALCA TG
2 struma ovarii 10.4 NKX2-1 TG
3 suppurative thyroiditis 10.4 CALCA TG
4 thyroid sarcoma 10.4 CALCA TG
5 melanomatosis 10.4 HRAS NRAS
6 giant congenital nevus 10.4 HRAS NRAS
7 ovarian germ cell cancer 10.4 NKX2-1 TG
8 athyreosis 10.4 NKX2-1 TG
9 chromosome 14q11-q22 deletion syndrome 10.4 HRAS NKX2-1
10 schimmelpenning-feuerstein-mims syndrome 10.4 HRAS NRAS
11 hypoadrenalism 10.3 CALCA TG
12 ovarian melanoma 10.3 HRAS NRAS
13 papillary thymic adenocarcinoma 10.3 CD5 TG
14 malignant conjunctival melanoma 10.3 HRAS NRAS
15 marcus gunn phenomenon 10.3 HRAS NRAS
16 amyloid tumor 10.3 CALCA TG
17 mature teratoma of the ovary 10.3 ENO2 TG
18 nodular malignant melanoma 10.3 HRAS NRAS
19 secondary hypertrophic osteoarthropathy 10.3 CALCA HRAS
20 lung adenoid cystic carcinoma 10.3 HRAS NKX2-1
21 pancreatic somatostatinoma 10.3 CALCA ENO2
22 somatostatinoma 10.3 CALCA ENO2
23 lymphoepithelioma-like thymic carcinoma 10.3 CD5 TG
24 shrimp allergy 10.3 ACTB LGALS3
25 duodenal somatostatinoma 10.3 CALCA ENO2
26 benign struma ovarii 10.3 HRAS NRAS TG
27 malignant ectomesenchymoma 10.3 ENO2 HRAS
28 ectomesenchymoma 10.3 ENO2 HRAS
29 nontoxic goiter 10.3 CALCA TG
30 lung oat cell carcinoma 10.3 CALCA ENO2
31 ovarian germ cell teratoma 10.3 NKX2-1 NRAS TG
32 papillary thyroid microcarcinoma 10.3 CALCA NKX2-1 TG
33 ovarian cystic teratoma 10.3 CALCA NKX2-1 TG
34 small cell carcinoma of the bladder 10.2 ENO2 NKX2-1
35 sigmoid neoplasm 10.2 CEACAM5 HRAS
36 conventional fibrosarcoma 10.2 ENO2 NRAS
37 myelodysplastic myeloproliferative cancer 10.2 HRAS NRAS
38 apocrine adenoma 10.2 CEACAM5 HRAS
39 nodular goiter 10.2 CALCA LGALS3 TG
40 crustacean allergy 10.2 ACTB LGALS3
41 pancreatic cystadenocarcinoma 10.2 CALCA CEACAM5
42 clear cell adenoma 10.2 CEACAM5 TG
43 colloid adenoma 10.2 LGALS3 NKX2-1 TG
44 melanocytic nevus syndrome, congenital 10.2 HRAS NRAS
45 hypothyroidism, congenital, nongoitrous, 2 10.2 LGALS3 NKX2-1 TG
46 aggressive digital papillary adenocarcinoma 10.2 CEACAM5 HRAS
47 hashimoto thyroiditis 10.2 CALCA LGALS3 TG
48 prostate small cell carcinoma 10.2 ENO2 NKX2-1
49 acute thyroiditis 10.2 CALCA ENO2 TG
50 mucinous bronchioloalveolar adenocarcinoma 10.2 LGALS3 NKX2-1

Graphical network of the top 20 diseases related to Fetal Adenoma:



Diseases related to Fetal Adenoma

Symptoms & Phenotypes for Fetal Adenoma

MGI Mouse Phenotypes related to Fetal Adenoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.7 ACTB HRAS NKX2-1 NR4A1 NR4A3 NRAS
2 growth/size/body region MP:0005378 9.61 ACTB ENO2 HRAS LGALS3 NKX2-1 NR4A1
3 neoplasm MP:0002006 9.17 ACTB HRAS LGALS3 NKX2-1 NR4A1 NR4A3

Drugs & Therapeutics for Fetal Adenoma

Search Clinical Trials , NIH Clinical Center for Fetal Adenoma

Genetic Tests for Fetal Adenoma

Anatomical Context for Fetal Adenoma

MalaCards organs/tissues related to Fetal Adenoma:

42
Thyroid, Lung, Breast, Prostate, Testis, Salivary Gland, Thymus

Publications for Fetal Adenoma

Articles related to Fetal Adenoma:

# Title Authors Year
1
Microfollicular adenoma of ectopic thyroid gland masquerading as salivary gland tumor - a diagnostic and therapeutic challenge: a case report. ( 25103611 )
2014
2
Involvement of the HMGI(Y) gene in a microfollicular adenoma of the thyroid. ( 10451711 )
1999
3
Lung carcinoma metastatic to microfollicular adenoma of the thyroid. A case report. ( 2239314 )
1990
4
Fetal adenoma of the thyroid. A common source for false-positive thallium-201/technetium-99m pertechnetate subtraction parathyroid scintigraphy. ( 2886243 )
1987
5
Signet-ring cell microfollicular adenoma arising in a nodular ectopic thyroid. A case report. ( 3104557 )
1986
6
Fetal adenoma of the pigmented ciliary epithelium associated with persistent hyperplastic primary vitreous. ( 3785893 )
1986
7
Mucin producing microfollicular adenoma of the thyroid. ( 3973051 )
1985
8
Reverse discordant behavior in microfollicular adenoma of thyroid. Case report. ( 2998673 )
1985
9
Signet-cell-simulating microfollicular adenoma of the thyroid. ( 6383090 )
1984

Variations for Fetal Adenoma

Expression for Fetal Adenoma

Search GEO for disease gene expression data for Fetal Adenoma.

Pathways for Fetal Adenoma

GO Terms for Fetal Adenoma

Biological processes related to Fetal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 thyroid gland development GO:0030878 9.16 NKX2-1 TG
2 regulation of type B pancreatic cell proliferation GO:0061469 8.96 NR4A1 NR4A3
3 cellular response to corticotropin-releasing hormone stimulus GO:0071376 8.62 NR4A1 NR4A3

Molecular functions related to Fetal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.26 ACTB NKX2-1 NR4A1 NR4A3
2 glucocorticoid receptor binding GO:0035259 8.62 NR4A1 NR4A3

Sources for Fetal Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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