FASD
MCID: FTL006
MIFTS: 43

Fetal Alcohol Spectrum Disorder (FASD)

Categories: Fetal diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Fetal Alcohol Spectrum Disorder

MalaCards integrated aliases for Fetal Alcohol Spectrum Disorder:

Name: Fetal Alcohol Spectrum Disorder 12 15
Fetal Alcohol Spectrum Disorders 52 71
Alcohol-Related Neurodevelopmental Disorder - Type 52
Alcohol-Related Birth Defects - Type 52
Fetal Alcohol Syndrome - Type 52
Fetal Alcohol Syndrome 71
Fasd 52

Classifications:



External Ids:

Disease Ontology 12 DOID:0050696
UMLS 71 C0015923 C2985290

Summaries for Fetal Alcohol Spectrum Disorder

Disease Ontology : 12 A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.

MalaCards based summary : Fetal Alcohol Spectrum Disorder, also known as fetal alcohol spectrum disorders, is related to alcohol-related neurodevelopmental disorder and alcohol-related birth defect. An important gene associated with Fetal Alcohol Spectrum Disorder is BDNF (Brain Derived Neurotrophic Factor), and among its related pathways/superpathways are superpathway of tryptophan utilization and Tyrosine metabolism. The drugs Ethanol and Choline have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and testes, and related phenotypes are craniofacial and no phenotypic analysis

Wikipedia : 74 Fetal alcohol spectrum disorders (FASDs) are a group of conditions that can occur in a person whose... more...

Related Diseases for Fetal Alcohol Spectrum Disorder

Diseases in the Fetal Alcohol Syndrome family:

Fetal Alcohol Spectrum Disorder

Diseases related to Fetal Alcohol Spectrum Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 214)
# Related Disease Score Top Affiliating Genes
1 alcohol-related neurodevelopmental disorder 33.3 SLC27A5 PFAS PAF1
2 alcohol-related birth defect 33.3 SLC27A5 PFAS CYP2E1 ADH1B
3 alcohol use disorder 32.5 SLC27A5 KDM4C H2AC18 GRIN2B CYP2E1 BDNF
4 fetal alcohol syndrome 32.4 SLC27A5 SHH PVALB PFAS PAF1 MIR9-1
5 substance abuse 31.0 SLC27A5 H2AC18 CYP2E1 BDNF ADH1B
6 alcohol dependence 30.9 GRIN2B CYP2E1 BDNF ALDH9A1 AKR1A1 ADH6
7 autism spectrum disorder 30.7 SHH MIR140 GRIN2B CASP3 BDNF ADNP
8 autism 30.6 SHH KDM4C GRIN2B CASP3 BDNF ADNP
9 status epilepticus 30.5 PVALB GRIN2B CASP3 BDNF
10 mental depression 30.5 H2AC18 GRIN2B BDNF
11 disease of mental health 30.3 PVALB MIR9-1 MIR30A MIR140 KDM4C H2AC18
12 traumatic brain injury 30.3 CASP3 BDNF
13 orofacial cleft 30.2 SHH MIR140 KDM4C H2AC18
14 fragile x syndrome 30.2 PVALB MIR9-1 H2AC18 GRIN2B BDNF
15 psychotic disorder 30.1 SLC27A5 PVALB MIR9-1 H2AC18 GRIN2B BDNF
16 pervasive developmental disorder 30.0 PVALB MIR9-1 MIR140 KDM4C H2AC18 GRIN2B
17 partial fetal alcohol syndrome 11.7
18 attention deficit-hyperactivity disorder 10.6
19 methanol poisoning 10.5 CYP2E1 AKR1A1 ADH1B
20 neonatal hypoxic and ischemic brain injury 10.5 PVALB BDNF
21 chromosome 16p13.3 deletion syndrome, proximal 10.5 MIR9-1 KDM4C H2AC18
22 alcoholic cardiomyopathy 10.5 CYP2E1 ADH6 ADH1B
23 global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies 10.5
24 occlusion precerebral artery 10.5 GRIN2B CASP3 BDNF
25 germ cell and embryonal cancer 10.5 MIR9-1 KDM4C H2AC18
26 ectodermal dysplasia 1, hypohidrotic, x-linked 10.5 H2AC18 CASP3 BDNF
27 hyaline fibromatosis syndrome 10.5 SHH GRIN2B BDNF
28 non-syndromic intellectual disability 10.5 MIR9-1 H2AC18 ADNP
29 oropharynx cancer 10.4 MIR9-1 H2AC18 CASP3
30 drug dependence 10.4 BDNF ADH6 ADH1B
31 inherited metabolic disorder 10.4 MIR9-1 MIR30A KDM4C H2AC18
32 leukocyte disease 10.4 MIR30A MIR140 KDM4C H2AC18
33 mature b-cell neoplasm 10.4 MIR9-1 KDM4C H2AC18
34 infratentorial cancer 10.4 SHH MIR9-1 KDM4C H2AC18
35 nasopharyngeal disease 10.4 MIR9-1 MIR30A MIR140 H2AC18
36 pharynx cancer 10.4 MIR9-1 MIR30A MIR140 H2AC18
37 cell type benign neoplasm 10.4 MIR30A MIR140 KDM4C H2AC18
38 upper respiratory tract disease 10.4 MIR9-1 MIR30A MIR140 H2AC18
39 esophageal disease 10.4 MIR30A MIR140 KDM4C H2AC18
40 alacrima, achalasia, and mental retardation syndrome 10.4
41 substance dependence 10.4 H2AC18 CYP2E1 BDNF ADH1B
42 alcoholic liver cirrhosis 10.4 CYP2E1 AKR1A1 ADH1B
43 cervix disease 10.4 MIR9-1 MIR30A MIR140 H2AC18
44 bone cancer 10.4 MIR9-1 MIR140 KDM4C H2AC18
45 overnutrition 10.4 MIR30A MIR140 KDM4C H2AC18
46 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 10.4 H2AC18 CASP3 BDNF
47 retinal cancer 10.4 MIR9-1 KDM4C H2AC18 CASP3
48 autosomal genetic disease 10.4 MIR9-1 MIR140 KDM4C H2AC18
49 kaufman oculocerebrofacial syndrome 10.4 PVALB H2AC18 GRIN2B BDNF
50 tobacco addiction 10.4 H2AC18 CYP2E1 BDNF ADH1B

Graphical network of the top 20 diseases related to Fetal Alcohol Spectrum Disorder:



Diseases related to Fetal Alcohol Spectrum Disorder

Symptoms & Phenotypes for Fetal Alcohol Spectrum Disorder

MGI Mouse Phenotypes related to Fetal Alcohol Spectrum Disorder:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.5 AKR1A1 BDNF CASP3 CYP2E1 L1CAM PFAS
2 no phenotypic analysis MP:0003012 9.17 BDNF CASP3 GRIN2B KDM4C L1CAM PVALB

Drugs & Therapeutics for Fetal Alcohol Spectrum Disorder

Drugs for Fetal Alcohol Spectrum Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 2, Phase 3 64-17-5 702
2
Choline Approved, Nutraceutical Phase 2, Phase 3 62-49-7 305
3 Neurotransmitter Agents Phase 3
4 Adrenergic Agents Phase 3
5 Atomoxetine Hydrochloride Phase 3
6 Hypolipidemic Agents Phase 2, Phase 3
7 Lipid Regulating Agents Phase 2, Phase 3
8 Gastrointestinal Agents Phase 2, Phase 3
9 Antimetabolites Phase 2, Phase 3
10
Glycerol Approved, Investigational Phase 2 56-81-5 753
11 Protective Agents Phase 2
12
Nitric Oxide Approved 10102-43-9 145068
13
tannic acid Approved 1401-55-4
14
Benzocaine Approved, Investigational 94-09-7, 1994-09-7 2337
15
Nicotine Approved 54-11-5 942 89594
16
leucovorin Approved 58-05-9 6006 143
17
Folic acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
18
Epigallocatechin Experimental, Investigational 970-74-1 72277
19
Epigallocatechin gallate Investigational 989-51-5 65064
20
Imidacloprid Vet_approved 105827-78-9 86418
21 Antioxidants
22 Neuroprotective Agents
23 Vitamins
24 Vitamin B Complex
25 Folate
26 Vitamin B9

Interventional clinical trials:

(show top 50) (show all 53)
# Name Status NCT ID Phase Drugs
1 An Open-label Study of the Long Term Tolerability and Safety of Atomoxetine in Treating the Inattention, Impulsivity and Hyperactivity in Children With Fetal-Alcohol Syndrome or Effects. Completed NCT00418262 Phase 3 Atomoxetine
2 A Randomized, Double-Blind, Placebo-controlled Clinical Trial of Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Development Not yet recruiting NCT04395196 Phase 2, Phase 3
3 Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders Completed NCT01911299 Phase 2
4 Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure Completed NCT01149538 Phase 1, Phase 2 Choline bitartrate
5 Fetal Alcohol Syndrome/ARND Research Consortion-Oklahoma Completed NCT00164554 Phase 1, Phase 2
6 Neurocognitive Habilitation for Children With FAS/ARND Completed NCT00164346 Phase 1, Phase 2
7 Study to Investigate the Effectiveness of a Math Intervention for Children With Fetal Alcohol Syndrome or Related Condition Completed NCT00164229 Phase 1, Phase 2
8 A Media Based Motivational Intervention to Reduce Alcohol Exposed Pregnancies (AEPs) Completed NCT00219336 Phase 2
9 Project CHOICES Efficacy Study for Preventing Alcohol-Exposed Pregnancies Completed NCT00153478 Phase 2
10 Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders Recruiting NCT02735473 Phase 2 Choline bitartrate;Placebo
11 Neighborhood Alcohol & HIV Prevention in South African Townships (Philani) Active, not recruiting NCT00996528 Phase 2
12 A Study of the Efficacy of Atomoxetine in Treating the Inattention, Impulsivity and Hyperactivity in Children With Fetal Alcohol Syndrome or Effects Completed NCT00417794 Phase 1 Strattera;Placebo
13 Computer-delivered SBIRT for Alcohol Use in Pregnancy: Planning a Stage II Trial Completed NCT01643044 Phase 1
14 Prevention of Fetal Alcohol Spectrum Disorder (FASD) by the Use of Technology Unknown status NCT02759874
15 Development, Implementation, and Evaluation of an Internet-based Behavioural Sleep Intervention for Children With NDD and Insomnia Unknown status NCT02694003
16 Effects of Hyperbaric Oxygen Therapy on Cognitive Function on Autistic Spectrum Disordered Children Unknown status NCT00631215
17 Strongest Families FASD: Parent Training for Challenging Behaviour in Children With Fetal Alcohol Spectrum Disorder (FASD) Completed NCT02210455
18 Evaluating the Effectiveness of an Attachment-Focused Intervention in Preschool Children With Fetal Alcohol Spectrum Disorder (FASD) or At-risk for FASD: A Randomized Controlled Field Trial Completed NCT01536184
19 Improving Self Regulation in Children With Fetal Alcohol Syndrome Spectrum Disorders: A Neuroplastic Intervention Completed NCT02457676
20 Neuromodulation Augmented Cognitive Remediation to Improve Executive Dysfunction in Fetal Alcohol Spectrum Disorder (FASD) Completed NCT03361293
21 Development of Education Materials for Prevention of Fetal Alcohol Syndrome (FAS) in Russia Completed NCT01971398
22 "Brief Alcohol Intervention: The Healthy Moms Project." Completed NCT00244062
23 Fetal Alcohol Spectrum Disorder-Is This a Ciliopathy? Completed NCT03802708
24 Self-Regulation in Adolescents With FASD: The Efficacy of a Targeted Intervention Completed NCT02912962
25 Reducing Alcohol Exposed Pregnancy Risk Completed NCT01446653
26 Dog-Assisted Therapy for Children and Adolescents With FASD: a Randomized Controlled Pilot Study Completed NCT04038164
27 Preventing FAS/ARND in Russian Children Completed NCT01961050
28 Newborn Phosphatidylethanol Screening to Detect Fetal Alcohol Exposure in Uruguay Completed NCT02600624
29 Prevention of Fetal Alcohol Damage Using Maternal Blood Markers Completed NCT00696085
30 A Randomized Clinical Trial of the Contraception and Alcohol Risk Reduction Internet Intervention to Reduce AEP Risk in Community Women Completed NCT02128880
31 Preventing FAS/ARND in Russian Children/Expansion to Interdisciplinary HIV Prevention in Women Completed NCT01994603
32 Comprehensive Program for Youth Mental Health Completed NCT02169960
33 Epigallocatechin Gallate (EGCG) as Therapeutic Tool to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) Children Completed NCT02558933
34 Early Identification of Affected Children and Nutritional Risk Factors for FASD in Ukraine Completed NCT03782935
35 Modeling and Testing Change in Mental Abilities in Childhood Through Computer-based Interventions Completed NCT02459873
36 Effects of Hyperbaric Oxygen Therapy on Clinical Symptoms and Markers of Inflammation and Oxidative Stress in Autistic Children: A Pilot Study Completed NCT00324909 Hyperbaric Oxygen Therapy
37 Face Anthropometric Pattern Recognition Technology, Based on 3D Reconstruction Technology, for Computer Aided Diagnosis of Human Genetic Disorders. Multicenter Collaborative Study. Completed NCT00705055
38 A Prospective, Randomized, Double-Blind, Controlled Study on the Clinical Effects of Hyperbaric Therapy in Autistic Children Completed NCT00335790
39 Feasibility Trial of the FMF Connect Mobile Health Intervention Recruiting NCT04194489
40 Development of an Epigenetic Biomarker for Prediction of Fetal Alcohol Spectrum Disorder Recruiting NCT03494738
41 Dissecting the Genetics of Fetal Alcohol Spectrum Disorders Recruiting NCT04072809
42 In Utero Alcoholic Exposure: PlGF, Biomarker of Fetal Brain Lesions Recruiting NCT03371641
43 The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology Recruiting NCT04026620
44 Parent Emotion Socialization and Child Emotion Regulation in FASD Recruiting NCT03524664
45 Native-Changing High-risk Alcohol Use and Increasing Contraception Effectiveness Study Recruiting NCT03930342
46 Preventing Alcohol Exposed Pregnancy Among Urban Native Young Women: Mobile CHOICES Recruiting NCT04376346
47 Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial Recruiting NCT03342495
48 The Effectiveness of an Educational Program on Parenting Stress and Coping Mechanism Among Parents of Children With Autism Spectrum Disorder in Amman, Jordan Recruiting NCT03805828
49 Food and Alcohol Behavior Study: Meaningful Enhancement Recruiting NCT04095052
50 Behavioral Exploration of Cognitive and Emotional Alterations in Adult Individuals Exposed to Alcohol During the Prenatal Period Active, not recruiting NCT03793920

Search NIH Clinical Center for Fetal Alcohol Spectrum Disorder

Genetic Tests for Fetal Alcohol Spectrum Disorder

Anatomical Context for Fetal Alcohol Spectrum Disorder

MalaCards organs/tissues related to Fetal Alcohol Spectrum Disorder:

40
Brain, Cortex, Testes, Fetal Brain, Cerebellum, Eye, Prefrontal Cortex

Publications for Fetal Alcohol Spectrum Disorder

Articles related to Fetal Alcohol Spectrum Disorder:

(show top 50) (show all 1654)
# Title Authors PMID Year
1
A review of studies exploring fetal alcohol spectrum disorders through eye tracking measures. 61
32470497 2020
2
Proceedings of the 2019 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group. 61
32171771 2020
3
A randomized controlled trial of transcranial direct-current stimulation and cognitive training in children with fetal alcohol spectrum disorder. 61
32360392 2020
4
Characterizing Alcohol-Related Neurodevelopmental Disorder: Prenatal Alcohol Exposure and the Spectrum of Outcomes. 61
32173870 2020
5
Fetal alcohol spectrum disorder among pre-adopted and foster children. 61
32493264 2020
6
Chronic Binge Alcohol Exposure During Pregnancy Alters mTOR System in Rat Fetal Hippocampus. 61
32333810 2020
7
Ophthalmologic Findings in Fetal Alcohol Spectrum Disorders - A Cohort Study From Childhood to Adulthood. 61
31926885 2020
8
Incontinence in persons with fetal alcohol spectrum disorders: a polish cohort. 61
32222270 2020
9
Cognitive and social/emotional influences on adaptive functioning in children with FASD: Clinical and cultural considerations. 61
32519571 2020
10
Sleep disturbance as a predictor of anxiety in children with Fetal Alcohol Spectrum Disorders and typically developing children. 61
32224364 2020
11
Moderate prenatal alcohol exposure alters the number and function of GABAergic interneurons in the murine orbitofrontal cortex. 61
32540413 2020
12
Short Exposure to Moderate Concentration of Alcohol During Embryonic Development Does Not Alter Gross Morphology in Zebrafish. 61
32493176 2020
13
Experiences of Children with Fetal Alcohol Spectrum Disorder and Their Families: A Critical Review. 61
32282931 2020
14
Neurocognitive Function and Fetal Alcohol Spectrum Disorder in Offenders with Mental Disorders. 61
32051201 2020
15
Caregiver-reported physical health status of children and young people with fetal alcohol spectrum disorder. 61
32513328 2020
16
A qualitative examination of the cognitive and behavioural challenges experienced by children with fetal alcohol spectrum disorder. 61
32521433 2020
17
The Demographic and Neurocognitive Profile of Clients Diagnosed With Fetal Alcohol Spectrum Disorder in PATCHES Paediatrics Clinics Across Western Australia and the Northern Territory. 61
32333805 2020
18
'That thing in his head': Aboriginal and non-Aboriginal Australian caregiver responses to neurodevelopmental disability diagnoses. 61
32579286 2020
19
Increased ethanol intake is associated with social anxiety in offspring exposed to ethanol on gestational day 12. 61
32535179 2020
20
Phosphatidylethanol Levels in Postpartum Women and Their Newborns in Uruguay and Brazil. 61
32441809 2020
21
Hippocampal transcriptome analysis following maternal separation implicates altered RNA processing in a mouse model of fetal alcohol spectrum disorder. 61
32416732 2020
22
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood. 61
32202514 2020
23
Single-day Postnatal Alcohol Exposure Induces Apoptotic Cell Death and Causes long-term Neuron Loss in Rodent Thalamic Nucleus Reuniens. 61
32251710 2020
24
Rescue of ethanol-induced FASD-like phenotypes via prenatal co-administration of choline. 61
32044264 2020
25
Postnatal Ethanol-Induced Neurodegeneration Involves CB1R-Mediated β-Catenin Degradation in Neonatal Mice. 61
32370076 2020
26
Early Ethanol Exposure Inhibits the Differentiation of Hippocampal Dentate Gyrus Granule Cells in a Mouse Model of Fetal Alcohol Spectrum Disorders. 61
32220014 2020
27
Corrigendum: Graded Cerebellar Lobular Volume Deficits in Adolescents and Young Adults with Fetal Alcohol Spectrum Disorders (FASD). 61
32249891 2020
28
Motor performance and sensory processing behaviors among children with fetal alcohol spectrum disorders compared to children with developmental coordination disorders. 61
32446153 2020
29
Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish. 61
32173352 2020
30
Community-based child development service fetal alcohol spectrum disorder assessment: A retrospective clinic audit. 61
31944476 2020
31
Fetal alcohol spectrum disorders: Genetic and epigenetic mechanisms. 61
32386259 2020
32
In utero MRI identifies consequences of early-gestation alcohol drinking on fetal brain development in rhesus macaques. 61
32312804 2020
33
Ethanol exposure during the brain growth spurt affects social behavior and increases susceptibility to acute ethanol effects during adolescence in male mice. 61
32077124 2020
34
Alterations in the whole brain network organization after prenatal ethanol exposure. 61
31855302 2020
35
Teacher-Reported Prevalence of FASD in Kindergarten in Canada: Association with Child Development and Problems at Home. 61
32472249 2020
36
Difficulties in Daily Living Experienced by Adolescents, Transition-Aged Youth, and Adults With Fetal Alcohol Spectrum Disorder. 61
32472600 2020
37
Maternal iron nutriture modulates placental development in a rat model of fetal alcohol spectrum disorder. 61
31734307 2020
38
Fetus morphology changes by second-trimester ultrasound in pregnant women drinking alcohol. 61
30811093 2020
39
Postnatal Ethanol Exposure Activates HDAC-Mediated Histone Deacetylation, Impairs Synaptic Plasticity Gene Expression and Behavior in Mice. 61
32170298 2020
40
Maternal alcohol consumption during pregnancy associates with bone fractures in early childhood. A birth-cohort study of 6718 participants. 61
32485362 2020
41
Fetal Alcohol Spectrum Disorders in a Midwestern City: Child Characteristics, Maternal Risk Traits, and Prevalence. 61
32293735 2020
42
Reduced Hippocampal Volumes Partially Mediate Effects of Prenatal Alcohol Exposure on Spatial Navigation on a Virtual Water Maze Task in Children. 61
32196695 2020
43
Fetal Alcohol Spectrum Disorders in a Southeastern County of the United States: Child Characteristics and Maternal Risk Traits. 61
32293734 2020
44
Fetal Alcohol Spectrum Disorders in a Rocky Mountain Region City: Child Characteristics, Maternal Risk Traits, and Prevalence. 61
32293732 2020
45
Neurodevelopment in adolescents and adults with fetal alcohol spectrum disorders (FASD): A magnetic resonance region of interest analysis. 61
31930998 2020
46
Kcnn2 blockade reverses learning deficits in a mouse model of fetal alcohol spectrum disorders. 61
32203497 2020
47
Hydrogen Sulfide Attenuates the Neurotoxicity in the Animal Model of Fetal Alcohol Spectrum Disorders. 61
31900896 2020
48
A Mobile Health Intervention for Fetal Alcohol Spectrum Disorders (Families Moving Forward Connect): Development and Qualitative Evaluation of Design and Functionalities. 61
32250274 2020
49
Increased Notching of the Corpus Callosum in Fetal Alcohol Spectrum Disorder: A Callosal Misunderstanding? 61
32193189 2020
50
Prenatal Drinking in the Northern Plains: Differences Between American Indian and Caucasian Mothers. 61
32061456 2020

Variations for Fetal Alcohol Spectrum Disorder

Expression for Fetal Alcohol Spectrum Disorder

Search GEO for disease gene expression data for Fetal Alcohol Spectrum Disorder.

Pathways for Fetal Alcohol Spectrum Disorder

GO Terms for Fetal Alcohol Spectrum Disorder

Biological processes related to Fetal Alcohol Spectrum Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.62 PFAS CYP2E1 CASP3 BDNF
2 response to ethanol GO:0045471 9.54 GRIN2B CYP2E1 ADH6
3 ethanol oxidation GO:0006069 9.26 ADH6 ADH1B
4 oxidation-reduction process GO:0055114 9.17 SLC27A5 KDM4C CYP2E1 ALDH9A1 AKR1A1 ADH6
5 cellular aldehyde metabolic process GO:0006081 9.16 ALDH9A1 AKR1A1
6 learning or memory GO:0007611 9.13 GRIN2B CASP3 BDNF

Molecular functions related to Fetal Alcohol Spectrum Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.17 SLC27A5 KDM4C CYP2E1 ALDH9A1 AKR1A1 ADH6
2 alcohol dehydrogenase activity, zinc-dependent GO:0004024 9.16 ADH6 ADH1B
3 retinol dehydrogenase activity GO:0004745 9.13 AKR1A1 ADH6 ADH1B

Sources for Fetal Alcohol Spectrum Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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