LUTO
MCID: FTL074
MIFTS: 18

Fetal Lower Urinary Tract Obstruction (LUTO)

Categories: Fetal diseases, Nephrological diseases, Rare diseases
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Aliases & Classifications for Fetal Lower Urinary Tract Obstruction

MalaCards integrated aliases for Fetal Lower Urinary Tract Obstruction:

Name: Fetal Lower Urinary Tract Obstruction 58 33
Other Atresia or Stenosis of Urethra or Bladder Neck 33
Fetal Luto - [lower Urinary Tract Obstruction] 33
Luto 58

Classifications:

Orphanet: 58  
Rare renal diseases
Developmental anomalies during embryogenesis


External Ids:

Orphanet 58 ORPHA435365
ICD11 33 1661120971

Summaries for Fetal Lower Urinary Tract Obstruction

MalaCards based summary: Fetal Lower Urinary Tract Obstruction, also known as other atresia or stenosis of urethra or bladder neck, is related to posterior urethral valves and atresia of urethra. Affiliated tissues include kidney.

Related Diseases for Fetal Lower Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Fetal Lower Urinary Tract Obstruction:



Diseases related to Fetal Lower Urinary Tract Obstruction

Symptoms & Phenotypes for Fetal Lower Urinary Tract Obstruction

Drugs & Therapeutics for Fetal Lower Urinary Tract Obstruction

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction (LUTO): A Prospective Trial Recruiting NCT03281798
2 Validation of the Standardized Prenatal Clinical Management of Fetuses With Lower Urinary Tract Obstruction (LUTO) Recruiting NCT02315521

Search NIH Clinical Center for Fetal Lower Urinary Tract Obstruction

Genetic Tests for Fetal Lower Urinary Tract Obstruction

Anatomical Context for Fetal Lower Urinary Tract Obstruction

Organs/tissues related to Fetal Lower Urinary Tract Obstruction:

MalaCards : Kidney

Publications for Fetal Lower Urinary Tract Obstruction

Articles related to Fetal Lower Urinary Tract Obstruction:

(show top 50) (show all 127)
# Title Authors PMID Year
1
Fetal therapy of LUTO (lower urinary tract obstruction) - a follow-up observational study. 62
34652254 2022
2
Obstetric outcomes after fetal intervention - a single-center descriptive review. 62
36411675 2022
3
Fetal Megacystis in the first trimester: Comparing management and outcomes between longitudinal bladder length groups. 62
36372362 2022
4
Prenatally Diagnosed Posterior Urethral Valves: Ethical Dilemmas of Fetal Intervention. 62
35680050 2022
5
Management of very young fetuses with LUTO. 62
35882994 2022
6
Reply to 'Management of very young fetuses with LUTO'. 62
35882995 2022
7
Chronic Kidney Disease in Boys with Posterior Urethral Valves-Pathogenesis, Prognosis and Management. 62
36009441 2022
8
Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group. 62
35136187 2022
9
Pathological and sonographic review of early isolated severe lower urinary tract obstruction and implications for prenatal treatment. 62
34182598 2022
10
Early 2nd trimester vesico-amniotic shunt insertion promises a new era of better outcomes for fetuses with isolated severe lower urinary tract obstruction (LUTO). 62
35307334 2022
11
Vesico-amniotic shunt insertion prior to the completion of 16 weeks results in improved preservation of renal function in surviving fetuses with isolated severe lower urinary tract obstruction (LUTO). 62
35337732 2022
12
Vesicoamniotic Shunting before 17 + 0 Weeks in Fetuses with Lower Urinary Tract Obstruction (LUTO): Comparison of Somatex vs. Harrison Shunt Systems. 62
35566484 2022
13
Vesico-amniotic shunt insertion prior to the completion of 16 weeks results in improved preservation of renal function in surviving fetuses with isolated severe lower urinary tract obstruction (LUTO). 62
35123910 2022
14
Development and in-vitro characterization of a novel fetal vesicoamniotic shunt - The Vortex shunt. 62
35048376 2022
15
Urine Biochemistry of a Human Fetus with Urinary Tract Obstruction - A Case Report. 62
35225147 2022
16
Evaluating the impact of pop-off mechanisms in boys with posterior urethral valves. 62
36330367 2022
17
Genome-wide association study in patients with posterior urethral valves. 62
36238604 2022
18
[DISTENDED FETAL BLADDER]. 62
34957714 2021
19
Z-scores of fetal bladder size for antenatal differential diagnosis between posterior urethral valves and urethral atresia. 62
33864313 2021
20
Prenatally diagnosed lower urinary tract obstruction: A 15-year experience at two tertiary centers in Japan. 62
34155735 2021
21
Genome-Wide Survey for Microdeletions or -Duplications in 155 Patients with Lower Urinary Tract Obstructions (LUTO). 62
34573432 2021
22
Peritoneal-amniotic shunt in management of urinary ascites complicating fetal lower urinary tract obstruction. 62
32770819 2021
23
Predictive accuracy of prenatal ultrasound findings for lower urinary tract obstruction: A systematic review and Bayesian meta-analysis. 62
34318486 2021
24
Novel scoring system for determining fetal candidacy for prenatal intervention for severe congenital lower urinary tract obstruction. 62
34010724 2021
25
Fetoscopic urethral meatotomy in fetuses with lower urinary tract obstruction by congenital megalourethra. 62
33792084 2021
26
Fetal interventions for congenital renal anomalies. 62
34189109 2021
27
Selection of candidates for foetal intervention in congenital lower urinary tract obstruction. 62
33620890 2021
28
Therapeutic intervention for fetal lower urinary tract obstruction: Current evidence and future strategies. 62
33583743 2021
29
Fetal Lower Urinary Tract Obstruction Complicated by Bladder Perforation. 62
33795406 2021
30
Perinatal outcome and prognostic factors of fetal megacystis diagnosed at 11-14 week's gestation. 62
33219696 2021
31
Evaluation of the Fetal Therapy Evidence in Lower Urinary Tract Obstruction: Would an ERAS Guideline Improve Outcomes? 62
34350862 2021
32
Evaluation of Sequential Urine Analysis when Selecting Candidates for Vesicoamniotic Shunting in Lower Urinary Tract Obstruction. 62
33756463 2021
33
Fetal lower urinary tract obstruction: a current overview of intrauterine diagnosis and treatment. 62
34020562 2021
34
Urethroplasty with balloon catheterization in fetal lower urinary tract obstruction: observational study of 10 fetuses. 62
31763721 2020
35
Fetal bladder outflow obstruction: Interventions, outcomes and management uncertainties. 62
32978001 2020
36
Serial Amnioinfusion as Regenerative Therapy for Pulmonary Hypoplasia in Fetuses With Intrauterine Renal Failure or Severe Renal Anomalies: Systematic Review and Future Perspectives. 62
32793867 2020
37
Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction. 62
32787795 2020
38
Antenatal intervention for congenital fetal lower urinary tract obstruction (LUTO): a systematic review and meta-analysis. 62
30501534 2020
39
Biometric and morphological features on magnetic resonance imaging of fetal bladder in lower urinary tract obstruction: new perspectives for fetal cystoscopy. 62
31006924 2020
40
Fetal lower urinary tract obstruction: What should we tell the prospective parents? 62
32065667 2020
41
Neurodevelopmental Outcome in Infants with Lower Urinary Tract Obstruction Based on Different Degrees of Severity. 62
32146466 2020
42
Fetal Cystoscopy and Vesicoamniotic Shunting in Lower Urinary Tract Obstruction: Long-Term Outcome and Current Technical Limitations. 62
31401627 2020
43
Prediction model of postnatal renal function in fetuses with lower urinary tract obstruction (LUTO)-Development and internal validation. 62
31659787 2019
44
Fetal cardiac findings and hemodynamic changes associated with severe lower urinary tract obstruction in utero. 62
30908816 2019
45
Outcome of fetuses with lower urinary tract obstruction and normal amniotic fluid volume in second trimester of pregnancy. 62
30977189 2019
46
Congenital urinary tract obstruction. 62
30819578 2019
47
First-year profile of biomarkers for early detection of renal injury in infants with congenital urinary tract obstruction. 62
30694385 2019
48
Myocardial function in fetuses with lower urinary tract obstruction: Is there a cardiac remodeling effect due to renal damage? 62
30957256 2019
49
Fetal megacystis: a lot more than LUTO. 62
30043466 2019
50
The role of renal biomarkers to predict the need of surgery in congenital urinary tract obstruction in infants. 62
30979613 2019

Variations for Fetal Lower Urinary Tract Obstruction

Expression for Fetal Lower Urinary Tract Obstruction

Search GEO for disease gene expression data for Fetal Lower Urinary Tract Obstruction.

Pathways for Fetal Lower Urinary Tract Obstruction

GO Terms for Fetal Lower Urinary Tract Obstruction

Sources for Fetal Lower Urinary Tract Obstruction

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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