MCID: FTL064
MIFTS: 26

Fetal Methylmercury Syndrome

Categories: Fetal diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Fetal Methylmercury Syndrome

MalaCards integrated aliases for Fetal Methylmercury Syndrome:

Name: Fetal Methylmercury Syndrome 52 58
Minamata Disease 52 58
Methyl Mercury Antenatal Infection 58
Methyl Mercury Antenatal Exposure 52

Characteristics:

Orphanet epidemiological data:

58
fetal methylmercury syndrome
Inheritance: Not applicable; Age of onset: Antenatal,Neonatal;

Classifications:

Orphanet: 58  
Developmental anomalies during embryogenesis
Teratologic disorders


External Ids:

ICD10 via Orphanet 33 T56.1
UMLS via Orphanet 72 C0086626 C0265376
Orphanet 58 ORPHA1917

Summaries for Fetal Methylmercury Syndrome

NIH Rare Diseases : 52 The following summary is from Orphanet , a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 1917 Definition A rare disorder characterized by a group of symptoms that may be observed in a foetus or newborn when the mother was exposed during pregnancy to excessive amounts of methylmercury. Epidemiology Accidents have led to the birth of about 800 affected children worldwide over the last 50 years. Clinical description In the late-1950s, methylmercury toxicity became highly publicised after an outbreak of cerebral palsy and microcephaly in newborns from the fishing village of Minimata Bay, Japan. These abnormalities were caused by methylmercury contamination of fish in the bay, and were termed Minimata Disease. Similar intoxications also occurred in Iraq after seeds contaminated with methylmercury were mistakenly used to make bread. In this population, infants exposed in utero displayed psychomotor retardation and cerebral palsy. Similar neurological impairment has been reported in other instances of food contamination, such as in infants of American Indian women who ingested pork contaminated with phenylmercuric acetate. Etiology There are two main types of mercury, metallic mercury (a heavy liquid element at room temperature, used in thermometers) and organic mercury (like methylmercury, used as antifungal agent in seed dressings). The selective neurotoxicity of organic mercury does not appear to apply to metallic mercury and its salts. Methylmercury is lipophilic and more readily distributed to the brain tissue than mercuric salts. Metallic mercury does not cross the placenta readily, and it has been estimated that the rate of methylmercury transport into the brain may exceed that of mercury by a factor of 10. Diagnostic methods Exposure to methylmercury can be monitored by measuring the concentration in the hair. All fish contain some methylmercury, and frequent consumption of highly contaminated fish can lead to a hair concentration of methylmercury ranging between 10 and 50 ppm. A level of 50 ppm in hair has been established as the lowest toxic level, and the World Health Organization (WHO) has applied a safety factor of 10 to cover risks in the most sensitive populations. Thus, 5 ppm has been generally adopted as the international standard for the upper tolerable level of mercury in hair. Management and treatment Since maternal exposure to methylmercury is primarily through fish consumption, it is recommended that women of childbearing age should not consume more than 350g of fish per week. In addition, they should not be occupationally exposed to air concentrations of mercury vapor greater than 0.01 mg. per cubic meter, to inorganic and phenylmercuric compounds at concentrations greater than 0.02 mg per cubic meter, or to any detectable concentration of methylmercury. Visit the Orphanet disease page for more resources.

MalaCards based summary : Fetal Methylmercury Syndrome, also known as minamata disease, is related to mercury poisoning and ataxia and polyneuropathy, adult-onset. Affiliated tissues include brain, placenta and cortex, and related phenotypes are muscular hypotonia and hearing impairment

Related Diseases for Fetal Methylmercury Syndrome

Diseases related to Fetal Methylmercury Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 35, show less)
# Related Disease Score Top Affiliating Genes
1 mercury poisoning 11.7
2 ataxia and polyneuropathy, adult-onset 10.4
3 tremor 10.4
4 cerebral palsy 10.4
5 aceruloplasminemia 10.2
6 paresthesia 10.2
7 neuropathy 10.1
8 pathologic nystagmus 10.1
9 cerebellar degeneration 10.1
10 diencephalic syndrome 10.1
11 spasticity 10.1
12 spondylosis, cervical 10.0
13 strabismus 10.0
14 arachnoid cysts, intracranial 10.0
15 retinitis pigmentosa 10.0
16 gastric cancer 10.0
17 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
18 neuroretinitis 10.0
19 nephrotic syndrome 10.0
20 low compliance bladder 10.0
21 spondylosis 10.0
22 sensory peripheral neuropathy 10.0
23 retinitis 10.0
24 liver disease 10.0
25 brain edema 10.0
26 poliomyelitis 10.0
27 peripheral nervous system disease 10.0
28 paraplegia 10.0
29 cerebrovascular disease 10.0
30 cataract 10.0
31 speech disorder 10.0
32 mechanical strabismus 10.0
33 wallerian degeneration 10.0
34 cerebral atrophy 10.0
35 encephalopathy 10.0

Graphical network of the top 20 diseases related to Fetal Methylmercury Syndrome:



Diseases related to Fetal Methylmercury Syndrome

Symptoms & Phenotypes for Fetal Methylmercury Syndrome

Human phenotypes related to Fetal Methylmercury Syndrome:

58 31 (showing 5, show less)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 muscular hypotonia 58 31 hallmark (90%) Very frequent (99-80%) HP:0001252
2 hearing impairment 58 31 hallmark (90%) Very frequent (99-80%) HP:0000365
3 short stature 58 31 hallmark (90%) Very frequent (99-80%) HP:0004322
4 microcephaly 58 31 hallmark (90%) Very frequent (99-80%) HP:0000252
5 visual impairment 58 31 hallmark (90%) Very frequent (99-80%) HP:0000505

Drugs & Therapeutics for Fetal Methylmercury Syndrome

Search Clinical Trials , NIH Clinical Center for Fetal Methylmercury Syndrome

Genetic Tests for Fetal Methylmercury Syndrome

Anatomical Context for Fetal Methylmercury Syndrome

MalaCards organs/tissues related to Fetal Methylmercury Syndrome:

40
Brain, Placenta, Cortex, Testes, Cerebellum, Endothelial, Spleen

Publications for Fetal Methylmercury Syndrome

Articles related to Fetal Methylmercury Syndrome:

(showing 280, show less)
# Title Authors PMID Year
1
Lessons From an Early-stage Epidemiological Study of Minamata Disease. 61
31685724 2020
2
Mercury speciation in preserved historical sludge: Potential risk from sludge contained within reclaimed land of Minamata Bay, Japan. 61
31648069 2020
3
Toxicity of mercury: Molecular evidence. 61
31881386 2019
4
Mercury cycling in the terrestrial, aquatic and atmospheric environment of the Slovak Republic - an overview. 61
31232059 2019
5
Cerebellar Transcranial Magnetic Stimulation Improves Ataxia in Minamata Disease. 61
31543798 2019
6
Mercury pollution in modern times and its socio-medical consequences. 61
30448663 2019
7
Methylmercury-induced neural degeneration in rat dorsal root ganglion is associated with the accumulation of microglia/macrophages and the proliferation of Schwann cells. 61
30842371 2019
8
Chronic Neurological Disease Due to Methylmercury Poisoning. 61
30278852 2018
9
Accelerated functional losses in ageing congenital Minamata disease patients. 61
30102975 2018
10
Methylmercury causes epigenetic suppression of the tyrosine hydroxylase gene in an in vitro neuronal differentiation model. 61
29856999 2018
11
Health Impacts and Biomarkers of Prenatal Exposure to Methylmercury: Lessons from Minamata, Japan. 61
30081479 2018
12
Survey of the Extent of the Persisting Effects of Methylmercury Pollution on the Inhabitants around the Shiranui Sea, Japan. 61
30037044 2018
13
Potential therapeutic effect of repetitive transcranial magnetic stimulation for tremor in Minamata disease: A case report. 61
29627030 2018
14
[Mercury as a Global Pollutant and Mercury Exposure Assessment and Health Effects]. 61
30270289 2018
15
Methylmercury promotes prostacyclin release from cultured human brain microvascular endothelial cells via induction of cyclooxygenase-2 through activation of the EGFR-p38 MAPK pathway by inhibiting protein tyrosine phosphatase 1B activity. 61
28958600 2017
16
Temporal trends of infant and birth outcomes in Minamata after severe methylmercury exposure. 61
28967567 2017
17
Activation of interleukin-6 and -8 expressions by methylmercury in human U937 macrophages involves RelA and p50. 61
27917510 2017
18
An inter-laboratory comparison of different analytical methods for the determination of monomethylmercury in various soil and sediment samples: A platform for method improvement. 61
27855329 2017
19
Novel carbon nanotube (CNT)-based ultrasensitive sensors for trace mercury(II) detection in water: A review. 61
27539821 2017
20
Effects of Prenatal Methylmercury Exposure: From Minamata Disease to Environmental Health Studies. 61
28931792 2017
21
Secondary sex ratio in regions severely exposed to methylmercury "Minamata disease". 61
26497019 2016
22
Neurological and neurocognitive functions from intrauterine methylmercury exposure. 61
26267674 2016
23
Three Case Reports of Successful Vibration Therapy of the Plantar Fascia for Spasticity Due to Cerebral Palsy-Like Syndrome, Fetal-Type Minamata Disease. 61
27082608 2016
24
[Food Sanitation Act and Minamata Disease]. 61
26832624 2016
25
Characteristics of hand tremor and postural sway in patients with fetal-type Minamata disease. 61
27853104 2016
26
Recent Epidemiological Studies on Methylmercury, Mercury and Selenium. 61
27725427 2016
27
Evaluation of mercury exposure level, clinical diagnosis and treatment for mercury intoxication. 61
26807265 2016
28
[Textual research for Tibetan medicine Qumazi]. 61
26390671 2015
29
Tracking the fate of mercury in the fish and bottom sediments of Minamata Bay, Japan, using stable mercury isotopes. 61
25877383 2015
30
The role of calcium and cyclic nucleotide signaling in cerebellar granule cell migration under normal and pathological conditions. 61
25066767 2015
31
[Clinical aspects of the Niigata Minamata disease]. 61
25585433 2015
32
[Epidemiology of Minamata Disease--Focus on the Clinical Features Related to the 1977 Diagnostic Criteria]. 61
26411946 2015
33
Intrauterine Exposure to Methylmercury and Neurocognitive Functions: Minamata Disease. 61
24971622 2015
34
Association between social group participation and perceived health among elderly inhabitants of a previously methylmercury-polluted area. 61
24643882 2014
35
Methylmercury exposure and neurological outcomes in Taiji residents accustomed to consuming whale meat. 61
24685489 2014
36
S-mercuration of cellular proteins by methylmercury and its toxicological implications. 61
25242398 2014
37
[History of ignorance of methylmercury toxicity and intoxication in Japan in relation to Minamata disease]. 61
24476597 2014
38
Signs and symptoms of methylmercury contamination in a First Nations community in Northwestern Ontario, Canada. 61
24091119 2014
39
Lower urinary tract symptoms in patients with Niigata Minamata disease: a case-control study 50 years after methyl mercury pollution. 61
23163739 2013
40
Cerebellar abnormalities typical of methylmercury poisoning in a fledged saltmarsh sparrow, Ammodramus caudacutus. 61
23478946 2013
41
Expression of VEGF-related proteins in cultured human brain microvascular endothelial cells and pericytes after exposure to methylmercury. 61
24213003 2013
42
Critical appraisal of the 1977 diagnostic criteria for Minamata disease. 61
23298421 2013
43
Global trends in mercury management. 61
23230466 2012
44
Rescue of neuronal migration deficits in a mouse model of fetal Minamata disease by increasing neuronal Ca2+ spike frequency. 61
22411806 2012
45
Role of intracellular defense factors against methylmercury toxicity. 61
23123460 2012
46
Vibration therapy of the plantar fascia improves spasticity of the lower limbs of a patient with fetal-type Minamata disease in the chronic stage. 61
22675016 2011
47
[Bibliographical study of the toxicity of organic mercury compounds]. 61
21996777 2011
48
Recent evidence from epidemiological studies on methylmercury toxicity. 61
21996768 2011
49
Long-term exposure to methylmercury and psychiatric symptoms in residents of Minamata, Japan. 61
21470684 2011
50
Congenital minamata disease: intrauterine methylmercury poisoning. Teratology 18:285-8. 1978. 61
20973053 2010
51
The pathology of methylmercury poisoning (Minamata disease): The 50th Anniversary of Japanese Society of Neuropathology. 61
20500453 2010
52
[An examination of "Minamata disease general investigation and research liaison council"--The process of making uncertain the organic mercury causal theory]. 61
21032857 2010
53
What has methylmercury in umbilical cords told us? - Minamata disease. 61
19878970 2009
54
[Development of neurology in Japan and its contribution to elucidate and resolve the sociomedical problems]. 61
20030198 2009
55
[History of neurology and education on neurology in Japan]. 61
20030263 2009
56
Index of congenital Minamata disease in Canadian areas of concern in the Great Lakes: an eco-social epidemiological approach. 61
19953398 2009
57
Minamata disease: catastrophic poisoning due to a failed public health response. 61
19367301 2009
58
[Global lessons of Minamata disease--a man's worth]. 61
19227150 2009
59
Hair mercury concentrations of children and mothers in Korea: implication for exposure and evaluation. 61
18502474 2008
60
[Association between Minamata disease status and activities of daily living among inhabitants in previously methylmercury-polluted areas]. 61
18840944 2008
61
Somatosensory disturbance by methylmercury exposure. 61
17640630 2008
62
[Medical problems concerning Minamata disease and the approach by the Japanese Society of Psychiatry and Neurology]. 61
19291911 2008
63
The delayed appearance of a mercurial warning. 61
18091412 2008
64
Minamata disease revisited: an update on the acute and chronic manifestations of methyl mercury poisoning. 61
17681548 2007
65
Neurophysiological evidence of methylmercury neurotoxicity. 61
17450510 2007
66
[Comparison of current activities of daily living (ADL) scores of fetal-type minamata disease patients with their ADL scores 15 years ago and communication disorders of these patients]. 61
17575788 2007
67
[Pathological and biochemical studies of 30 Niigata autopsy cases related to Minamata disease]. 61
17334095 2007
68
[Methylmercury causes diffuse damage to the somatosensory cortex: how to diagnose Minamata disease]. 61
17642257 2007
69
Metallothioneins: mercury species-specific induction and their potential role in attenuating neurotoxicity. 61
17018868 2006
70
Recent advances in evaluation of health effects on mercury with special reference to methylmercury-A minireview. 61
21432376 2006
71
[Minamata disease: a neuropathological viewpoint]. 61
16532696 2006
72
Reappraisal of somatosensory disorders in methylmercury poisoning. 61
16087068 2005
73
[Factors relating to the conditions and characteristics of mental health among the inhabitants in a methylmercury polluted area]. 61
16130909 2005
74
Long-term follow-up study of health status in population living in methylmercury-polluted area. 61
16308560 2005
75
[Preparation of a "chronological table of main diseases in Japanese history" for pharmacy students of the 6-year program]. 61
17152837 2005
76
The severity of Minamata disease declined in 25 years: temporal profile of the neurological findings analyzed by multiple logistic regression model. 61
15635274 2005
77
Environmental distribution, analysis, and toxicity of organometal(loid) compounds. 61
15239389 2004
78
Social factors associated with psychological distress among inhabitants in a methyl-mercury polluted area in rural Japan. 61
15750582 2004
79
Cases of mercury exposure, bioavailability, and absorption. 61
12915150 2003
80
Mercury in hair and in fish consumed by Riparian women of the Rio Negro, Amazon, Brazil. 61
12909555 2003
81
[Health and socio-economic condition of certified Minamata disease patients, 1999]. 61
14533569 2003
82
Neurotoxicity of organomercurial compounds. 61
12835120 2003
83
Japanese experiences of environmental management. 61
12578167 2003
84
[Environmental problems and internal medicine--from the experience with Minamata Disease]. 61
12655687 2002
85
Autonomic nervous functions in fetal type Minamata disease patients: assessment of heart rate variability. 61
12630553 2002
86
[Contribution to the study of Minamata Disease by Japanese researchers]. 61
12652776 2002
87
An autopsy case of minamata disease (methylmercury poisoning)--pathological viewpoints of peripheral nerves. 61
12512873 2002
88
[Contribution of Japanese researchers to progress in the field of neurology in the last 100 years: Minamata disease]. 61
12373838 2002
89
[Neurotological long-term follow-up in Minamata disease in Niigata, Japan]. 61
11974878 2002
90
[On the exacerbation of the systems of fetal Minamata disease patients an urgent proposal of the urgent follow up study for the victims by environmental health hazards]. 61
11915316 2002
91
Logistic model analysis of neurological findings in Minamata disease and the predicting index. 61
11838584 2002
92
Evaluation of genotoxic and cytotoxic potential of thiola (N-2-mercaptopropionylglycine), a medicine used in the treatment of humans contaminated with mercury. 61
11813292 2002
93
[Bibliographical study of Minamata disease]. 61
11868395 2002
94
Clinical investigation of the lesions responsible for sensory disturbance in Minamata disease. 61
11874251 2001
95
Mercury pollution in the Tapajos River basin, Amazon: mercury level of head hair and health effects. 61
11686639 2001
96
Declining Minamata male birth ratio associated with increased male fetal death due to heavy methylmercury pollution. 61
11683592 2001
97
Methylmercury poisoning in common marmosets--a study of selective vulnerability within the cerebral cortex. 61
11695574 2001
98
Reappraisal of the historic 1959 cat experiment in Minamata by the Chisso Factory. 61
11725835 2001
99
Cerebellar blood flow in methylmercury poisoning (Minamata disease). 61
11338409 2001
100
Health assessment for mercury exposure among schoolchildren residing near a gold processing and refining plant in Apokon, Tagum, Davao del Norte, Philippines. 61
11032133 2000
101
Minamata disease. 61
11037181 2000
102
Mercury contamination in the Yatsushiro Sea, south-western Japan: spatial variations of mercury in sediment. 61
10989922 2000
103
Congenital Minamata disease: warnings from Japan's experience. 61
10921517 2000
104
Health surveillance in the population living in a methyl mercury-polluted area over a long period. 61
10856180 2000
105
[Total mercury in hair samples of inhabitants of Tapajós River, Pará State, Brazil]. 61
10881131 2000
106
[Reconsideration on "clinico-pathological study on the autopsy cases showing glove-and-stocking type sensory disturbance in relation to Minamata disease"]. 61
10810895 2000
107
[Fetal methylmercury syndrome]. 61
11057159 2000
108
Differential diagnosis between organic and inorganic mercury poisoning in human cases--the pathologic point of view. 61
10588547 1999
109
Methylmercury level in umbilical cords from patients with congenital Minamata disease. 61
10507148 1999
110
[An appraisal of the judgements of the Kumamoto Minamata Disease Certification Commission from May 1981 to July 1992 for applicants from December 1975 to April 1981]. 61
10479890 1999
111
Monitoring of mercury pollution in Tanzania: relation between head hair mercury and health. 61
10231987 1999
112
[Re: Studies of sensation disorders in Minamata disease. By Drs. Tsuda and Nakamura. Refutation]. 61
10610509 1999
113
Change and behavior of residual mercury in paddy soils and rice of Japan. 61
9753762 1998
114
The present mercury contents of scalp hair and clinical symptoms in inhabitants of the Minamata area. 61
9600809 1998
115
Methylmercury dose estimation from umbilical cord concentrations in patients with Minamata disease. 61
9600802 1998
116
MR findings of Minamata disease--organic mercury poisoning. 61
9562057 1998
117
Widespread neuronal degeneration in rats following oral administration of methylmercury during the postnatal developing phase: a model of fetal-type minamata disease. 61
9518689 1998
118
Mercury in the Amazon. 61
9666740 1998
119
Pathology of Minamata disease. 61
9437807 1997
120
[Causal inference in medicine: a reaction to the report, "incidence of Minamata disease in communities along the Agano River, Niigata, Japan--patterns of the exposure and official diagnosis of patients"]. 61
9301222 1997
121
Representation of the visual field in the striate cortex: comparison of MR findings with visual field deficits in organic mercury poisoning (Minamata disease). 61
9194440 1997
122
Migration of granule neurons in cerebellar organotypic cultures is impaired by methylmercury. 61
9175597 1997
123
[Cerebellar atrophy in Minamata disease: comparison with spino-cerebellar degeneration on MR images]. 61
9077090 1997
124
[An appraisal on the judgements of the Kumamoto Minamata Disease Certification Commission]. 61
9102475 1997
125
Comparison of heavy metal concentrations in human umbilical cord in 1980 and 1990. 61
8997086 1996
126
Evidence for delayed neurotoxicity produced by methylmercury. 61
9086479 1996
127
[Neurophysiological studies of minamata disease with HTLV-I associated myelopathy--a case report]. 61
8976128 1996
128
Cancer mortality in Minamata disease patients exposed to methylmercury through fish diet. 61
8952217 1996
129
Environmental health. 61
8800283 1996
130
[Incidence of Minamata disease in communities along the Agano river, Niigata, Japan--patterns of the exposure and official diagnosis of patients]. 61
8783877 1996
131
Human brain disturbance by methylmercury poisoning, focusing on the long-term effect on brain weight. 61
8784829 1996
132
Minamata disease redress settled. 61
8551833 1995
133
Neurologic features of chronic minamata disease (organic mercury poisoning) and incidence of complications with aging. 61
8522732 1995
134
Neurologic features of chronic Minamata disease (organic mercury poisoning) certified at autopsy. 61
8563113 1995
135
Minamata disease: methylmercury poisoning in Japan caused by environmental pollution. 61
7734058 1995
136
Concentration of mercury in hair of diseased people in Japan. 61
7874464 1995
137
Methylmercury induces apoptosis of rat cerebellar neurons in primary culture. 61
7945377 1994
138
Atmospheric pollution due to mobile sources and effects on human health in Japan. 61
7529709 1994
139
MR findings in seven patients with organic mercury poisoning (Minamata disease). 61
7985580 1994
140
MR imaging of minamata disease: qualitative and quantitative analysis. 61
7863032 1994
141
Mercury in the Umbilical Cord: Implications for Risk Assessment for Minamata Disease. 61
9679113 1994
142
[Health conditions among fishermen living in the Minamata disease prevalent area]. 61
8049511 1994
143
Profile of subjective complaints and activities of daily living among current patients with Minamata disease after 3 decades. 61
8243418 1993
144
Epidemiological and clinical features of Minamata disease. 61
8404770 1993
145
Environmental release of chemicals and reproductive ecology. 61
8243381 1993
146
Effects of methylmercury on the brain of infant rats reared artificially. 61
8211983 1993
147
[Influence of age and sex on threshold dose of mercury in Minamata disease as determined by hair mercury concentration]. 61
8329758 1993
148
A fetal type of Minamata disease. An autopsy case report with special reference to the nervous system. 61
1520402 1992
149
Truncal hypesthesia in patients with Minamata disease. 61
1600268 1992
150
The discovery of the causal agent of Minamata disease. 61
1536159 1992
151
Common factors contributing to intractable pain and medical problems with insufficient drug uptake in areas to be treated, and their pathogenesis and treatment: Part I. Combined use of medication with acupuncture, (+) Qi gong energy-stored material, soft laser or electrical stimulation. 61
1353650 1992
152
Minamata disease: a story of mercury's malevolence. 61
1948221 1991
153
Present mercury levels in red blood cells of nearby inhabitants about 30 years after the outbreak of Minamata disease. 61
1914996 1991
154
Minamata disease: A 1989 update on the mercury poisoning epidemic in Japan. 61
24202728 1991
155
Minamata disease: what is a keystone of its molecular mechanism? A biochemical theory on the nature of methyl mercury neurotoxicity. 61
2269614 1990
156
Serum immunoglobulin levels in monkeys treated with methylmercury. 61
2279459 1990
157
Neurospecific translation control and the problem of potent danger of drugs and chemicals: a caution. 61
2691419 1989
158
[Profile: Dr. Yaeko Itai, a physician involved in the care of patients with Minamata disease and now challenging a new area of hospital care]. 61
2733216 1989
159
Mercury level and histochemical distribution in a human brain with Minamata disease following a long-term clinical course of twenty-six years. 61
2562539 1989
160
Neurotological follow-up studies upon Minamata disease. 61
2635534 1989
161
Methylmercury and the health of autochthons in northwest Quebec. 61
3396257 1988
162
Minamata disease demonstrated by computed tomography. 61
3357567 1988
163
[Diagnostic problems in chronic Minamata disease (organic mercury poisoning)--with special reference to the neurological features and actual condition of complications]. 61
3581596 1987
164
Methylmercury exposure and mortality in southern Japan: a close look at causes of death. 61
3746182 1986
165
Mortality and survival for Minamata disease. 61
4086144 1985
166
[Computed tomography in chronic Minamata disease (organic mercury poisoning)--with special reference to comparison between the computed tomography of recognized Minamata disease patients and non-recognized ones]. 61
4092396 1985
167
Cutaneous and auditory function in rats following methyl mercury poisoning. 61
4035685 1985
168
Effect of organic mercury on the electrical resistance of phosphatidylserine bilayers. 61
4005237 1985
169
[Electrophysiologic and histopathologic studies on sural nerves from Minamata disease patients of delayed onset showing distal sensory impairments]. 61
3995852 1985
170
Mercury dispersion from Minamata Bay to the Yatsushiro Sea during 1975-1980. 61
6510323 1984
171
Mercury in feathers of wild birds from the mercury-polluted area along the shore of the Shiranui Sea, Japan. 61
6523130 1984
172
[Computed tomography in chronic Minamata disease (organic mercury poisoning)--quantitative analysis of computed tomography in the most recent cases of Minamata disease]. 61
6518692 1984
173
[Clinical features of chronic Minamata disease (organic mercury poisoning). Analysis of the neurological findings in the most recent 100 cases]. 61
6467744 1984
174
Comparison of the inhibitory effects of mercuric chloride on cytosolic and mitochondrial hexokinase activities in rat brain, kidney and spleen. 61
6146488 1984
175
Causes of death in Minamata disease: analysis of death certificates. 61
6480121 1984
176
Quantitative analysis of tremor in Minamata disease. 61
6636146 1983
177
Minamata disease (organic mercury poisoning): neuroradiologic and electrophysiologic studies. 61
6890643 1982
178
The Minamata disease. 61
7165023 1982
179
Urinary beta-2-microglobulin does not serve as diagnostic tool for Minamata disease. 61
6185093 1982
180
The many faces of methylmercury poisoning. 61
6763633 1982
181
[Congenital Minamata disease accompanied by arachnoid cyst (author's transl)]. 61
7093064 1982
182
Minamata disease. 61
22656217 1982
183
Pathology of Minamata disease. With special reference to its pathogenesis. 61
6765001 1982
184
[Mercury and methylmercury pollution of fishery products. Toxicological effects on human health (author's transl)]. 61
7340004 1981
185
[Neuro-pathological study on superior colliculus of Minamata disease, especially chronic and prolonged cases (author's transl)]. 61
7315656 1981
186
Grating test of contrast sensitivity in patients with Minamata disease. 61
7236573 1981
187
[One autopsy case of newly found congenital Minamata disease (author's transl)]. 61
7330116 1981
188
[A simple grating test for contrast sensitivity (Arden grating test) with Minamata disease (author's transl)]. 61
484383 1979
189
Congenital Minamata disease: intrauterine methylmercury poisoning. 61
362594 1978
190
A pathological study of prolonged cases of Minamata disease. With particular reference to 83 autopsy cses. 61
716883 1978
191
Ultrastructural changes of human sural nerves in the neuropathy induced by intrauterine methylmercury poisoning (so-called fetal Minamata disease). 61
417462 1978
192
[Psychiatric aspects of Minamata disease (author's transl)]. 61
601113 1977
193
Renal tubular dysfunction in Minamata disease. Detection of renal tubular antigen and beta-2-microglobin in the urine. 61
68693 1977
194
The outbreak of Minamata disease (methyl mercury poisoning) in cats on Northwestern Ontario reserves. 61
862594 1977
195
[Urinary protein analysis in toxic nephropathy suspected to be caused by heavy metals. 1. Organic mercury poisoning--Minamata disease]. 61
559830 1977
196
Pathological changes of human sural nerves in Minamato disease (methylmercury poisoning). Light and electron microscopic studies. 61
402737 1977
197
Apallic syndrome in chronic mercury poisoning. 61
199444 1977
198
Late changes in human sural nerves in Minamata disease and in nerves of rats with experimental organic mercury poisoning. 61
936978 1976
199
Minamata disease with a long-term follow-up. 61
1017915 1976
200
[Pathology of the occipital cortex of Minamata disease, especially chronic and prolonged cases (author's transl)]. 61
1239160 1975
201
Minamata disease--methyl mercury poisoning. 61
168241 1975
202
[Review of the film, "Medical Study of Minamata Disease"]. 61
1049332 1975
203
[Poisoning by organic mercury compounds-Minamata disease (author's transl)]. 61
1168749 1975
204
The neurologic effects of noxious marine creatures. 61
237736 1975
205
[Pathology of the occipital white matter of Minamata disease (2), especially the passing route of the internal sagittal stratum in prolonged and chronic cases]. 61
4476984 1974
206
[Pathogenesis of Minamata disease (methylmercury toxicosis)--with special reference to the standpoint of experimental pathology]. 61
4472805 1974
207
Minamata disease. A case report and a comparative study. 61
4774318 1973
208
[Neuroophthalmological findings and their transition of organic mercury poisoning, "Minamata disease", in Agano area of Niigata Prefacture (author's transl)]. 61
4799030 1973
209
[The 3rd outbreak of Minamata disease]. 61
4490870 1973
210
[Hearing, equilibrium function, olfactory sense, taste and speech disorders in patients with fetal Minamata disease]. 61
4676115 1972
211
[Discussion on Minamata disease]. 61
4675942 1972
212
[Minamata disease in the fetus]. 61
4675939 1972
213
[Neuro-ophthalmological studies on Minamata disease (methyl mercury poisoning)]. 61
4674246 1972
214
[Clinical and epidemiological study on Minamata disease in Niigata]. 61
4675937 1972
215
[Follow-up of Minamata disease--with special reference to pathology]. 61
4675938 1972
216
[Clinical study of Minamata disease progressing over a long period of time]. 61
4675936 1972
217
[Research on Minamata disease 10 years since its discovery]. 61
4483759 1972
218
Studies on the cause of the Niigata episode of Minamata disease outbreak. 61
5043163 1972
219
[Epidemiology of Minamata disease--epidemiological approach to the organomercury poisoning]. 61
4942701 1971
220
[Pathological changes of the peripheral nerves in Minamata disease in man: electron microscopic observation]. 61
5106516 1971
221
[Criticism on the Department of Welfare. Lack of initiative in incidents of Minamata disease and control of drugs]. 61
4992145 1970
222
[Minamata disease (mercury poisoning)]. 61
4989626 1970
223
[Development of disturbance of hearing acuity, vestibular function, sense of taste and speech in Minamata disease]. 61
5311775 1970
224
[On the prognosis of Minamata disease. A long-term follow-up study of persons poisoned with organic mercury]. 61
5468448 1970
225
Studies on the Niigata episode of Minamata disease outbreak. Investigation of causative agents of organic mercury poisoning in the district along the river Agano. 61
5464506 1970
226
Electron microscopic studies on experimental Minamata disease--changes caused by long term administration of a small amount of organic mercury compound. 61
5391349 1969
227
[Induction of neuro-encephalopathy in experimental organic mercury poisoning and Minamata disease]. 61
5817309 1969
228
[Sequelae of acquired Minamata disease. Symptoms and changes 4 1/2 - 7 1/2 years from onset]. 61
5816808 1969
229
[Clinical aspects of Minamata disease]. 61
5816807 1969
230
[Pathology of Minamata disease, with special reference to its pathogenesis]. 61
5816811 1969
231
[Experimental development of congenital Minamata disease]. 61
5816793 1969
232
[Mechanism of the outbreak of Minamata disease]. 61
5816794 1969
233
[Sanitary engineering aspects on Minamata disease]. 61
5816795 1969
234
An electron microscopic study on the experimental congenital Minamata disease in the rat. 61
5793493 1969
235
A short history of Minamata disease research and the present situation of mercury pollution in Japan. 61
4896829 1969
236
[Experimental studies on organic mercury poisoning, on the behavior of the Minamata disease causal agent in maternal bodies and its transfer to their infants via either placenta or breast milk]. 61
5818468 1969
237
[Minamata disease as observed by public health nurses]. 61
5190073 1968
238
[Electron microscopic studies on experimental Minamata disease--findings in the brain of rats with the sequelae of poisoning]. 61
5750610 1968
239
[Studies on the brain and bladder. 1. Clinical and experimental studies on minamata disease]. 61
5750052 1968
240
[Minamata disease]. 61
5750672 1968
241
Electroencephalographic studies of Minamata disease in children. 61
5653106 1968
242
[Minamata disease and its symptoms]. 61
5187095 1967
243
[Electron microscopic studies on experimental Minamata disease--mechanism of pathological changes in the granular cells of cerebellum]. 61
5628002 1967
244
[Histopathological changes of Purkinje cells in the cerebellum in Minamata disease]. 61
5631314 1967
245
[Mercury in food products. I. Minamata disease]. 61
5597080 1967
246
[Studies on the origin of the causative agent of Minamata disease. IX. Transition of the pollution of Minamata Bay and its neighbourhood]. 61
5626077 1967
247
[A study on congenital Minamata disease. 1. Effects of organic mercury administration on pregnant animals, with reference to the mercury content in the maternal and fetal organs]. 61
5630732 1967
248
[Transition of brain lesions in the chronic course of Minamata disease]. 61
6010164 1966
249
Medical rehabilitation for motor disturbance in Minamata disease. 61
5980235 1966
250
"The Minamata disease". 61
5180608 1966
251
Fetal Minamata disease. A neuropathological study of two cases of intrauterine intoxication by a methyl mercury compound. 61
5890913 1965
252
[Minamata disease in a 4-year-old boy]. 61
5861433 1965
253
[Experimental studies on the cause of Minamata disease in the cat. (2). Hg content of organs chronically intoxicated with fish and Hg-ethyl phosphates]. 61
5894379 1965
254
[TOXICITY AND METABOLISM OF METHYL MERCURY COMPOUNDS IN ANIMALS--ESPECIALLY IN RELATION TO MINAMATA DISEASE]. 61
14322137 1965
255
(STUDIES ON THE ORGANIC MERCURY COMPOUND IN THE FISH AND SHELLFISH FROM MINAMATA BAY AS THE CAUSATIVE AGENT OF MINAMATA DISEASE AND THE FORMATION OF THE POISON. V. IR SPECTRA OF ALKYL MERCURY COMPOUNDS.) 61
14221956 1964
256
[STUDIES ON THE COURSE THAT THE CAUSATIVE AGENT OF MINAMATA DISEASE WAS FORMED, ESPECIALLY ON THE ORGANOMERCURY COMPOUND EXTRACTED FROM THE ACETALDEHYDE PLANT IN MINAMATA FACTORY AND THE ORGANOMERCURY COMPOUND CONTAINED IN THE SHELLFISH FROM MINAMATA BAY]. 61
14210852 1964
257
[EXPERIMENTAL STUDY ON ETIOLOGY OF MINAMATA DISEASE, ESPECIALLY ON INTOXICATION OF METHYLMERCURIC SULFIDE COMPOUNDS IN CATS]. 61
14162553 1964
258
[STUDIES ON THE ORIGIN OF THE CAUSATIVE AGENT OF MINAMATA DISEASE. IV. SYNTHESIS OF METHYL(METHYLTHIO)MERCURY]. 61
14140137 1964
259
[CONSIDERATION OF THE TOXICITY OF METHYLMERCURIC COMPOUNDS AND THE CAUSATIVE AGENT OF MINAMATA DISEASE]. 61
14150048 1963
260
[STUDIES ON THE COURSE THAT THE CAUSATIVE AGENT OF MINAMATA DISEASE WAS FORMED, ESPECIALLY ON THE ACCUMULATION OF THE MERCURY COMPOUND IN THE FISH AND SHELLFISH OF MINAMATA BAY]. 61
14092162 1963
261
[A EXPERIMENTAL STUDY OF MINAMATA DISEASE, ESPECIALLY ON THE HISTOCHEMICAL DEMONSTRATION OF MERCURY IN THE TISSUES]. 61
14054414 1963
262
Water pollution and Minamata disease. 61
14033236 1963
263
[Neurological studies on Minamata disease]. 61
13980349 1963
264
[Psychiatric studies on Minamata disease]. 61
13956597 1963
265
MINAMATA DISEASE. 61
14061445 1963
266
[Identification of the causal agent of Minamata disease with an organic mercury compound, methylmethyl-mercuric sulfide, with special reference to its chemical synthesis and animal experiments]. 61
13956598 1962
267
[Isolation and identification of an organic mercury compound from the shelfish Hormomya mutabilis Gould, causal source of Minamata disease]. 61
13954717 1962
268
[Organomercury compounds and Minamata disease. Subtle changes within the organism]. 61
13987554 1962
269
Studies on the origin of the causative agent of Minamata disease. III. Industrial wastes containing mercury compounds from Minamata Factory. 61
13956701 1962
270
[The pathological studies on the brain of experimental Minamata disease in cats]. 61
13918984 1962
271
[Neuropathological study of Minamata disease]. 61
14471279 1961
272
Minamata disease. 61
13755287 1961
273
Studies on Minamata disease. I. Establishment of the criterion for etiological reserch in mice. 61
14496123 1961
274
[Study of the causes of so-called Minamata disease and its mechanism of development. XXVII. Effect of vitamin B on the mouse poisoned by thallium]. 61
13775193 1961
275
[Study of the causes of so-called Minamata disease and its mechanism of development. XXVII. Effect of vitamin B-1 on the chicken poisoned by thallium]. 61
13729047 1961
276
Minamata disease. 61
13777231 1961
277
Minamata disease. The outbreak of a neurologic disorder in Minamata, Japan, and its relationship to the ingestion of seafood contaminated by mercuric compounds. 61
13755288 1960
278
Pathologic observations of the Minamata disease. 61
13919260 1959
279
MINAMATA disease. 61
13644822 1959
280
Minamata disease: an unusual neurological disorder caused by contaminated fish. 61
13588955 1958

Variations for Fetal Methylmercury Syndrome

Expression for Fetal Methylmercury Syndrome

Search GEO for disease gene expression data for Fetal Methylmercury Syndrome.

Pathways for Fetal Methylmercury Syndrome

GO Terms for Fetal Methylmercury Syndrome

Sources for Fetal Methylmercury Syndrome

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