MCID: FBR091
MIFTS: 19

Fibroblastic Rheumatism

Categories: Bone diseases, Rare diseases

Aliases & Classifications for Fibroblastic Rheumatism

MalaCards integrated aliases for Fibroblastic Rheumatism:

Name: Fibroblastic Rheumatism 58 70

Classifications:

Orphanet: 58  
Rare systemic and rhumatological diseases


External Ids:

Orphanet 58 ORPHA477650
UMLS 70 C1302753

Summaries for Fibroblastic Rheumatism

MalaCards based summary : Fibroblastic Rheumatism is related to fibromatosis and langerhans cell histiocytosis. An important gene associated with Fibroblastic Rheumatism is ACTC1 (Actin Alpha Cardiac Muscle 1), and among its related pathways/superpathways are Dilated cardiomyopathy and Striated Muscle Contraction. Affiliated tissues include skin, and related phenotype is cardiovascular system.

Related Diseases for Fibroblastic Rheumatism

Diseases related to Fibroblastic Rheumatism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 77)
# Related Disease Score Top Affiliating Genes
1 fibromatosis 29.9 DES ACTC1
2 langerhans cell histiocytosis 29.8 F13A1 CD163
3 non-langerhans-cell histiocytosis 28.9 F13A1 DES CD163 ACTC1
4 enthesopathy 10.8
5 arthropathy 10.3
6 raynaud phenomenon 10.2
7 multicentric reticulohistiocytosis 10.1
8 progressive nodular histiocytosis 10.0 F13A1 ACTC1
9 scleromyxedema 10.0 F13A1 ACTC1
10 acroosteolysis 10.0
11 juvenile arthritis 10.0
12 peripheral vascular disease 10.0
13 plica syndrome 10.0
14 vascular disease 10.0
15 ankylosis 10.0
16 synovitis 10.0
17 histiocytosis 10.0
18 skin disease 10.0
19 systemic scleroderma 10.0
20 connective tissue disease 10.0
21 neurofibroma 9.9 F13A1 ACTC1
22 fibrosarcoma 9.9 DES ACTC1
23 ovarian fibrothecoma 9.9 DES ACTC1
24 adult cystic nephroma 9.9 DES ACTC1
25 nephroma 9.9 DES ACTC1
26 benign metastasizing leiomyoma 9.9 DES ACTC1
27 leiomyoma 9.9 DES ACTC1
28 pulmonary vein stenosis 9.9 DES ACTC1
29 cutaneous leiomyosarcoma 9.9 DES ACTC1
30 leiomyosarcoma 9.9 DES ACTC1
31 botryoid rhabdomyosarcoma 9.9 DES ACTC1
32 parachordoma 9.9 DES ACTC1
33 rare tumor 9.9 DES ACTC1
34 syringocystadenoma papilliferum 9.9 DES ACTC1
35 glomangioma 9.9 DES ACTC1
36 spindle cell lipoma 9.9 DES ACTC1
37 reticulum cell sarcoma 9.9 DES ACTC1
38 ossifying fibromyxoid tumor 9.9 DES ACTC1
39 chondromyxoid fibroma 9.9 DES ACTC1
40 epithelioid leiomyosarcoma 9.9 DES ACTC1
41 myofibroma 9.8 F13A1 DES
42 congenital fibrosarcoma 9.8 DES ACTC1
43 pleomorphic liposarcoma 9.8 DES ACTC1
44 adenosarcoma 9.8 DES ACTC1
45 sarcomatoid mesothelioma 9.8 DES ACTC1
46 perivascular epithelioid cell tumor 9.8 DES ACTC1
47 pseudosarcomatous fibromatosis 9.8 DES ACTC1
48 patent foramen ovale 9.8 F13A1 ACTC1
49 infantile myofibromatosis 9.8 DES ACTC1
50 glomus tumor 9.8 DES ACTC1

Graphical network of the top 20 diseases related to Fibroblastic Rheumatism:



Diseases related to Fibroblastic Rheumatism

Symptoms & Phenotypes for Fibroblastic Rheumatism

MGI Mouse Phenotypes related to Fibroblastic Rheumatism:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 8.92 ACTC1 CD163 DES F13A1

Drugs & Therapeutics for Fibroblastic Rheumatism

Search Clinical Trials , NIH Clinical Center for Fibroblastic Rheumatism

Genetic Tests for Fibroblastic Rheumatism

Anatomical Context for Fibroblastic Rheumatism

MalaCards organs/tissues related to Fibroblastic Rheumatism:

40
Skin

Publications for Fibroblastic Rheumatism

Articles related to Fibroblastic Rheumatism:

(show all 44)
# Title Authors PMID Year
1
Firm Cutaneous Nodule on the Dorsal Hand: A Case Report on Fibroblastic Rheumatism. 61
33052274 2020
2
Fibroblastic Rheumatism Versus Variant Disease of Multinucleate Cell Angiohistiocytoma. 61
31725486 2020
3
Self-healing juvenile cutaneous mucinosis: Clinical and histopathologic findings of 9 patients: The relevance of long-term follow-up. 61
29066274 2018
4
Fibroblastic rheumatism: A case of multiple nodules of fingers and hands, contractures of fingers and polyarthritis. 61
29314178 2018
5
Fibroblastic rheumatism: the first case with infiltration of multinuclear giant cells and raised blood lead level. 61
25545215 2015
6
Fibroblastic rheumatism: immunosuppressive therapy is not always required. 61
24112952 2014
7
Fibroblastic rheumatism - case report. 61
24141350 2013
8
Multicentric reticulohistiocytosis and fibroblastic rheumatism. 61
23040366 2012
9
Fibroblastic rheumatism: a report of 4 cases with potential therapeutic implications. 61
21982057 2012
10
Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism. 61
20340022 2012
11
An unusual case of polyarthritis, skin nodules and patchy skin thickening: fibroblastic rheumatism. 61
22324960 2012
12
[Fibroblastic rheumatism. Case report]. 61
21676412 2012
13
Fibroblastic rheumatism: an addition to fibromatosis. 61
21549631 2011
14
An Asian case of fibroblastic rheumatism: clinical, radiological, and histological features. 61
20715301 2010
15
Fibroblastic rheumatism: fibromatosis rather than non-Langerhans cell histiocytosis. 61
19615014 2010
16
Response of fibroblastic rheumatism to infliximab. 61
20585484 2009
17
Fibroblastic rheumatism. 61
19076791 2009
18
Radiological bone lesions in fibroblastic rheumatism; case report. 61
17321366 2007
19
Fibroblastic rheumatism. 61
16891927 2006
20
Fibroblastic rheumatism: a Scandinavian case report. 61
15608318 2005
21
Fibroblastic rheumatism: a variant of non-Langerhans cell histiocytoses? 61
14521576 2003
22
Proliferation characteristics and polyploidization of cultured myofibroblasts from a patient with fibroblastic rheumatism. 61
14514418 2003
23
Fibroblastic rheumatism: case report and review of the literature. 61
12437558 2002
24
Multicentric reticulohistiocytosis: a rare cause of erosive arthropathy of the distal interphalangeal finger joints. 61
12006317 2002
25
Fibroblastic rheumatism: a case without rheumatological symptoms. 61
12353712 2002
26
[Fibroblastic rheumatism: a case report]. 61
11339131 2001
27
Fibroblastic rheumatism: clinical and histologic evolution of cutaneous manifestations. 61
9818674 1998
28
Fibroblastic rheumatism: a fifteen-year followup study. 61
9550498 1998
29
Histiocytes and fibroblastic rheumatism: comment on the article by Romas et al. 61
9485101 1998
30
Destructive arthropathy in fibroblastic rheumatism: comment on the article by Romas et al. 61
9485102 1998
31
The arthropathy of fibroblastic rheumatism. 61
9008615 1997
32
Preliminary experience with low-dose methotrexate in fibroblastic rheumatism. 61
8961914 1996
33
Fibroblastic rheumatism. 61
7778925 1995
34
Fibroblastic rheumatism. 61
8033396 1994
35
Fibroblastic rheumatism: clinical, histological, immunohistological, ultrastructural and biochemical study of a case. 61
7681316 1993
36
[Fibroblastic rheumatism]. 61
2360764 1990
37
[Fibroblastic rheumatism]. 61
2099695 1990
38
[Fibroblastic rheumatism]. 61
2099696 1990
39
Case report 511: Fibroblastic rheumatism. 61
2785291 1989
40
[Fibroblastic rheumatism. A clinical and histological entity]. 61
3258442 1988
41
[Fibroblastic rheumatism of the elderly. Histopathological, ultrastructural data and problems of differential diagnosis]. 61
3497429 1987
42
Fibroblastic rheumatism. 61
3722483 1986
43
[Fibroblastic rheumatism. A case with study of synovial histology]. 61
6981190 1982
44
[Fibroblastic rheumatism]. 61
6984299 1982

Variations for Fibroblastic Rheumatism

Expression for Fibroblastic Rheumatism

Search GEO for disease gene expression data for Fibroblastic Rheumatism.

Pathways for Fibroblastic Rheumatism

Pathways related to Fibroblastic Rheumatism according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.23 DES ACTC1
2 10.48 DES ACTC1

GO Terms for Fibroblastic Rheumatism

Cellular components related to Fibroblastic Rheumatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 8.62 F13A1 ACTC1

Biological processes related to Fibroblastic Rheumatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.62 DES ACTC1

Sources for Fibroblastic Rheumatism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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