MCID: FBR091
MIFTS: 23

Fibroblastic Rheumatism

Categories: Bone diseases, Rare diseases

Aliases & Classifications for Fibroblastic Rheumatism

MalaCards integrated aliases for Fibroblastic Rheumatism:

Name: Fibroblastic Rheumatism 59 73

Classifications:



External Ids:

Orphanet 59 ORPHA477650
UMLS 73 C1302753

Summaries for Fibroblastic Rheumatism

MalaCards based summary : Fibroblastic Rheumatism is related to fibromatosis and langerhans cell histiocytosis. An important gene associated with Fibroblastic Rheumatism is CD163 (CD163 Molecule), and among its related pathways/superpathways are Dilated cardiomyopathy (DCM) and Striated Muscle Contraction. Affiliated tissues include bone, skin and smooth muscle, and related phenotype is cardiovascular system.

Related Diseases for Fibroblastic Rheumatism

Diseases related to Fibroblastic Rheumatism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 fibromatosis 29.8 ACTC1 DES
2 langerhans cell histiocytosis 29.4 CD163 F13A1
3 non-langerhans-cell histiocytosis 28.9 ACTC1 CD163 DES F13A1
4 enthesopathy 10.2
5 ovarian fibrothecoma 10.0 ACTC1 DES
6 cutaneous leiomyosarcoma 10.0 ACTC1 DES
7 leiomyosarcoma 10.0 ACTC1 DES
8 botryoid rhabdomyosarcoma 10.0 ACTC1 DES
9 rhabdomyosarcoma 10.0 ACTC1 DES
10 spindle cell lipoma 10.0 ACTC1 DES
11 glomangioma 10.0 ACTC1 DES
12 parachordoma 10.0 ACTC1 DES
13 ossifying fibromyxoid tumor 10.0 ACTC1 DES
14 epithelioid leiomyosarcoma 10.0 ACTC1 DES
15 benign metastasizing leiomyoma 10.0 ACTC1 DES
16 leiomyoma 10.0 ACTC1 DES
17 pulmonary vein stenosis 10.0 ACTC1 DES
18 perivascular epithelioid cell tumor 10.0 ACTC1 DES
19 congenital fibrosarcoma 10.0 ACTC1 DES
20 ischemic fasciitis 10.0 ACTC1 DES
21 fasciitis 10.0 ACTC1 DES
22 reticulum cell sarcoma 10.0 ACTC1 DES
23 pseudosarcomatous fibromatosis 10.0 ACTC1 DES
24 dedifferentiated liposarcoma 10.0 ACTC1 DES
25 glomus tumor 10.0 ACTC1 DES
26 spindle cell sarcoma 10.0 ACTC1 DES
27 smooth muscle tumor 10.0 ACTC1 DES
28 infantile myofibromatosis 10.0 ACTC1 DES
29 chondromyxoid fibroma 10.0 ACTC1 DES
30 rhabdoid tumor predisposition syndrome 1 10.0 ACTC1 DES
31 angiomyolipoma 10.0 ACTC1 DES
32 spindle cell carcinoma 10.0 ACTC1 DES
33 familial isolated dilated cardiomyopathy 10.0 ACTC1 DES
34 carcinosarcoma 9.9 ACTC1 DES
35 inflammatory myofibroblastic tumor 9.9 ACTC1 DES
36 myofibroma 9.9 DES F13A1
37 juvenile xanthogranuloma 9.9 DES F13A1
38 giant cell tumor 9.9 ACTC1 DES
39 progressive nodular histiocytosis 9.9 ACTC1 F13A1
40 scleromyxedema 9.9 ACTC1 F13A1
41 restrictive cardiomyopathy 9.9 ACTC1 DES
42 endometrial stromal sarcoma 9.9 ACTC1 DES
43 arthropathy 9.9
44 gastrointestinal stromal tumor 9.9 ACTC1 DES
45 left ventricular noncompaction 9.8 ACTC1 DES
46 patent foramen ovale 9.8 ACTC1 F13A1
47 hypertrophic cardiomyopathy 9.8 ACTC1 DES
48 angiolipoma 9.7 ACTC1 DES F13A1
49 cutaneous fibrous histiocytoma 9.7 ACTC1 DES F13A1
50 hemangiopericytoma, malignant 9.7 ACTC1 DES F13A1

Graphical network of the top 20 diseases related to Fibroblastic Rheumatism:



Diseases related to Fibroblastic Rheumatism

Symptoms & Phenotypes for Fibroblastic Rheumatism

MGI Mouse Phenotypes related to Fibroblastic Rheumatism:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 8.92 ACTC1 CD163 DES F13A1

Drugs & Therapeutics for Fibroblastic Rheumatism

Search Clinical Trials , NIH Clinical Center for Fibroblastic Rheumatism

Genetic Tests for Fibroblastic Rheumatism

Anatomical Context for Fibroblastic Rheumatism

MalaCards organs/tissues related to Fibroblastic Rheumatism:

41
Bone, Skin, Smooth Muscle

Publications for Fibroblastic Rheumatism

Articles related to Fibroblastic Rheumatism:

(show all 31)
# Title Authors Year
1
Fibroblastic rheumatism: A case of multiple nodules of fingers and hands, contractures of fingers and polyarthritis. ( 29314178 )
2018
2
Fibroblastic rheumatism: the first case with infiltration of multinuclear giant cells and raised blood lead level. ( 25545215 )
2015
3
Fibroblastic rheumatism: immunosuppressive therapy is not always required. ( 24112952 )
2014
4
Fibroblastic rheumatism - case report. ( 24141350 )
2013
5
An unusual case of polyarthritis, skin nodules and patchy skin thickening: fibroblastic rheumatism. ( 22324960 )
2012
6
Fibroblastic rheumatism: a report of 4 cases with potential therapeutic implications. ( 21982057 )
2012
7
Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism. ( 20340022 )
2012
8
Multicentric reticulohistiocytosis and fibroblastic rheumatism. ( 23040366 )
2012
9
Fibroblastic rheumatism: an addition to fibromatosis. ( 21549631 )
2011
10
Fibroblastic rheumatism: fibromatosis rather than non-Langerhans cell histiocytosis. ( 19615014 )
2010
11
An Asian case of fibroblastic rheumatism: clinical, radiological, and histological features. ( 20715301 )
2010
12
Response of fibroblastic rheumatism to infliximab. ( 20585484 )
2009
13
Fibroblastic rheumatism. ( 19076791 )
2009
14
Radiological bone lesions in fibroblastic rheumatism; case report. ( 17321366 )
2007
15
Fibroblastic rheumatism. ( 16891927 )
2006
16
Fibroblastic rheumatism: a Scandinavian case report. ( 15608318 )
2005
17
Proliferation characteristics and polyploidization of cultured myofibroblasts from a patient with fibroblastic rheumatism. ( 14514418 )
2003
18
Fibroblastic rheumatism: a variant of non-Langerhans cell histiocytoses? ( 14521576 )
2003
19
Fibroblastic rheumatism: case report and review of the literature. ( 12437558 )
2002
20
Fibroblastic rheumatism: a case without rheumatological symptoms. ( 12353712 )
2002
21
Fibroblastic rheumatism: clinical and histologic evolution of cutaneous manifestations. ( 9818674 )
1998
22
Histiocytes and fibroblastic rheumatism: comment on the article by Romas et al. ( 9485101 )
1998
23
Destructive arthropathy in fibroblastic rheumatism: comment on the article by Romas et al. ( 9485102 )
1998
24
Fibroblastic rheumatism: a fifteen-year followup study. ( 9550498 )
1998
25
The arthropathy of fibroblastic rheumatism. ( 9008615 )
1997
26
Preliminary experience with low-dose methotrexate in fibroblastic rheumatism. ( 8961914 )
1996
27
Fibroblastic rheumatism. ( 7778925 )
1995
28
Fibroblastic rheumatism. ( 8033396 )
1994
29
Fibroblastic rheumatism: clinical, histological, immunohistological, ultrastructural and biochemical study of a case. ( 7681316 )
1993
30
Case report 511: Fibroblastic rheumatism. ( 2785291 )
1989
31
Fibroblastic rheumatism. ( 3722483 )
1986

Variations for Fibroblastic Rheumatism

Expression for Fibroblastic Rheumatism

Search GEO for disease gene expression data for Fibroblastic Rheumatism.

Pathways for Fibroblastic Rheumatism

Pathways related to Fibroblastic Rheumatism according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.19 ACTC1 DES
2 10.48 ACTC1 DES

GO Terms for Fibroblastic Rheumatism

Cellular components related to Fibroblastic Rheumatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 8.62 ACTC1 F13A1

Biological processes related to Fibroblastic Rheumatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.62 ACTC1 DES

Sources for Fibroblastic Rheumatism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....