Fibroma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: FBR054 MIFTS: 43	Fibroma Categories: Cancer diseases	Data Licensing For inquiries, contact: [email protected]
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Aliases & Classifications for Fibroma

MalaCards integrated aliases for Fibroma:

Name: Fibroma ¹¹ ⁷⁵ ²⁸ ⁵³ ⁴³ ¹⁴ ¹⁶

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:0050871

MeSH ⁴³ D005350

EFO ¹⁶ EFO_0002424

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Summaries for Fibroma

Disease Ontology: ¹¹ A connective tissue benign neoplasm composed of fibrous or connective tissues that derives from mesenchymal tissue.

MalaCards based summary: Fibroma is related to ossifying fibroma and skin tag. An important gene associated with Fibroma is MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Striated muscle contraction pathway. The drugs Prednisolone phosphate and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include bone, ovary and small intestine, and related phenotypes are homeostasis/metabolism and cellular

Wikipedia: ⁷⁵ Fibromas are benign tumors that are composed of fibrous or connective tissue. They can grow in all... more...

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Related Diseases for Fibroma

Diseases related to Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 837)

#	Related Disease	Score	Top Affiliating Genes
1	ossifying fibroma	32.4	USP6 SERPINA3 SATB2 NF1 CDC73 CD34
2	skin tag	32.4	SERPINA3 PTCH1 CD34
3	liver fibroma	32.1	VIM CALB2
4	testicular fibroma	32.0	CTNNB1 CD34 CALB2
5	basal cell nevus syndrome	31.7	PTCH1 NF1 CTNNB1
6	cutaneous fibrous histiocytoma	31.4	SERPINA3 S100A1 F13A1 DES CD68 CD34
7	fibromatosis	31.3	VIM DES CTNNB1 ACTC1
8	chondrosarcoma	31.2	VIM SERPINA3 S100A1 DES
9	desmoid tumor	31.0	DES CTNNB1 CD34 ACTC1
10	fibrosarcoma	31.0	VIM MALAT1 DES ACTC1
11	leiomyoma	30.8	VIM S100A1 DES CD34 ACTC1
12	tenosynovial giant cell tumor	30.7	USP6 SERPINA3 CD68
13	lipomatosis, multiple	30.6	SERPINA3 S100A1 NF1 DES CD34
14	ameloblastoma	30.6	SERPINA3 PTCH1 CTNNB1 CALB2
15	osteoblastoma	30.6	USP6 SATB2 CTNNB1
16	fasciitis	30.6	VIM USP6 DES CD34 ACTC1
17	chondroma	30.6	S100A1 NF1 CTNNB1 ACTC1
18	basal cell carcinoma	30.4	PTCH1 KRT7 F13A1 CTNNB1 CD34 ACTC1
19	perineurioma	30.4	VIM DES CD34 ACTC1
20	epulis	30.4	SERPINA3 KRT7 CDC73 CD68 CD34
21	giant cell reparative granuloma	30.3	USP6 SERPINA3 NF1 CD68
22	mesenchymal cell neoplasm	30.3	SERPINA3 NF1 CTNNB1 CD68 CD34
23	neurofibroma	30.2	VIM S100A1 NF1 F13A1 CD34 ACTC1
24	erythema elevatum diutinum	30.2	S100A9 CD34
25	sarcoma	30.2	VIM SERPINA3 S100A1 DES CTNNB1 CALB2
26	mixed cell type cancer	30.2	SERPINA3 KRT7 CTNNB1 CALB2
27	chordoma	30.2	VIM SERPINA3 S100A1 KRT7 DES CTNNB1
28	well-differentiated liposarcoma	30.2	SERPINA3 NF1 CD34
29	myoma	30.2	CD68 CD34 CALB2 ACTC1
30	myofibroma	30.2	USP6 S100A1 CD34
31	cowden syndrome	30.1	TSC1 PTCH1 NF1 CTNNB1
32	neuroma	30.1	SERPINA3 NF1 CD68 CD34
33	inflammatory myofibroblastic tumor	30.1	CTNNB1 CD68 CD34
34	congenital epulis	30.1	SERPINA3 S100A9 CD68
35	pericardial effusion	30.1	MUC16 CD68 CD34
36	chondroblastic osteosarcoma	30.0	SERPINA3 SATB2
37	mesenchymal chondrosarcoma	30.0	VIM KRT7 DES ACTC1
38	fibrous histiocytoma	30.0	VIM SERPINA3 F13A1 DES CD68 CD34
39	cystadenoma	30.0	SERPINA3 MUC16 KRT7 CALB2
40	obstructive jaundice	29.9	SERPINA3 MUC16 KRT7
41	myoblastoma	29.9	CD68 CALB2
42	benign teratoma	29.9	PTCH1 KRT7 CD34 CALB2
43	pseudosarcomatous fibromatosis	29.9	VIM USP6 SERPINA3 DES CTNNB1 CD68
44	dermatofibrosarcoma protuberans	29.8	VIM SERPINA3 S100A1 F13A1 DES CD68
45	signet ring cell adenocarcinoma	29.8	SERPINA3 KRT7 CTNNB1
46	fibrosarcomatous osteosarcoma	29.8	SERPINA3 SATB2
47	inguinal hernia	29.8	NF1 CD34 CALB2
48	adenoid cystic carcinoma	29.8	VIM SERPINA3 KRT7 CTNNB1 ACTC1
49	verruciform xanthoma of skin	29.8	SERPINA3 CD68
50	cutaneous leiomyosarcoma	29.8	CD68 CD34

Graphical network of the top 20 diseases related to Fibroma:

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Symptoms & Phenotypes for Fibroma

MGI Mouse Phenotypes related to Fibroma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.16	ACTC1 CD34 CDC73 CTNNB1 DES F13A1
2	cellular	MP:0005384	10	ACTC1 CD34 CDC73 CTNNB1 DES KRT7
3	muscle	MP:0005369	9.97	ACTC1 CDC73 CTNNB1 DES NF1 PTCH1
4	respiratory system	MP:0005388	9.61	CDC73 CTNNB1 F13A1 NF1 PTCH1 S100A1
5	hematopoietic system	MP:0005397	9.4	ACTC1 CD34 CD68 CDC73 CTNNB1 F13A1

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Drugs & Therapeutics for Fibroma

Drugs for Fibroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Prednisolone phosphate

Approved, Vet_approved

Phase 4

302-25-0

Prednisolone acetate

Approved, Vet_approved

Phase 4

52-21-1

Prednisolone

Approved, Vet_approved

Phase 4

50-24-8

4894 5755

Methylprednisolone hemisuccinate

Approved

Phase 4

2921-57-5

1875

Methylprednisolone

Approved, Vet_approved

Phase 4

83-43-2

4159 6741

Prednisolone hemisuccinate

Experimental

Phase 4

2920-86-7

4897

Methylprednisolone Acetate

Phase 4

584547

Sorafenib

Approved, Investigational

Phase 3

284461-73-0

216239

Protein Kinase Inhibitors

Phase 3

Toremifene

Approved, Investigational

Phase 2

89778-26-7

3005573

Doxorubicin

Approved, Investigational

Phase 2

23214-92-8

31703

Sirolimus

Approved, Investigational

Phase 1, Phase 2

53123-88-9

5284616 6436030

Miconazole

Approved, Investigational, Vet_approved

Phase 1, Phase 2

22916-47-8

4189

Clotrimazole

Approved, Vet_approved

Phase 1, Phase 2

23593-75-1

2812

Denosumab

Approved

Phase 2

615258-40-7

Cathine

Approved, Experimental, Illicit, Vet_approved, Withdrawn

Phase 2

14838-15-4, 492-39-7

131954576 4786 26934

Guaifenesin

Approved, Investigational, Vet_approved

Phase 2

93-14-1

3516

Nivolumab

Approved

Phase 2

946414-94-4

Ipilimumab

Approved

Phase 2

477202-00-9

Imidazole

Experimental, Investigational

Phase 2

288-32-4

795

Vaccines

Phase 2

Estrogens

Phase 2

Hormones

Phase 2

Hormone Antagonists

Phase 2

Antineoplastic Agents, Hormonal

Phase 2

Estrogen Receptor Modulators

Phase 2

Selective Estrogen Receptor Modulators

Phase 2

Imatinib Mesylate

Phase 2

220127-57-1

Immunosuppressive Agents

Phase 1, Phase 2

Immunologic Factors

Phase 1, Phase 2

Liposomal doxorubicin

Phase 2

Anti-Bacterial Agents

Phase 1, Phase 2

Anti-Infective Agents

Phase 1, Phase 2

Antifungal Agents

Phase 1, Phase 2

Antibiotics, Antitubercular

Phase 1, Phase 2

Chlorpheniramine, phenylpropanolamine drug combination

Phase 2

Immunoglobulins

Phase 2

Immune Checkpoint Inhibitors

Phase 2

Antibodies, Monoclonal

Phase 2

Antibodies

Phase 2

Antineoplastic Agents, Immunological

Phase 2

Triamcinolone

Approved, Vet_approved

Phase 1

124-94-7

31307

Triamcinolone hexacetonide

Phase 1

Triamcinolone diacetate

Phase 1

Triamcinolone Acetonide

Phase 1

6436

glucocorticoids

Phase 1

Anti-Inflammatory Agents

Phase 1

Estradiol

Approved, Investigational, Vet_approved

Early Phase 1

50-28-2

5757

Polyestradiol phosphate

Approved

Early Phase 1

28014-46-2

Cola

Interventional clinical trials:

(show all 38)

#	Name	Status	NCT ID	Phase	Drugs
1	Prospective Trial Comparing the Performance Profiles of Two Non-Cross-Linked Porcine Dermal Matrices in Abdominal Wall Reconstruction	Recruiting	NCT02228889	Phase 4
2	Percutaneous Needle Fasciotomy (PNF) +/- Corticosteroid Injection for Dupuytren's Contracture (DC) Affecting Metacarpophalangeal Joints (MCP) . A Randomized Controlled Trial	Not yet recruiting	NCT05440240	Phase 4	Corticosteroid injection
3	A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Nirogacestat Versus Placebo in Adult Patients With Progressing Desmoid Tumors/Aggressive Fibromatosis (DT/AF)	Active, not recruiting	NCT03785964	Phase 3	Nirogacestat oral tablet;Placebo Oral Tablet
4	A Phase III, Double Blind, Randomized, Placebo-Controlled Trial of Sorafenib in Desmoid Tumors or Aggressive Fibromatosis (DT/DF)	Active, not recruiting	NCT02066181	Phase 3	Sorafenib Tosylate
5	A Multi-Center, Open-Label, Extension Study to Evaluate the Long-Term Safety, Efficacy, and Durability of EN3835 in the Treatment and Retreatment of Plantar Fibromatosis	Enrolling by invitation	NCT05254457	Phase 3
6	Open Label Phase II Clinical Trial of Myoma Immunotherapy	Unknown status	NCT03550703	Phase 2
7	Toremifene in Desmoid Tumor: Prospective Clinical Trial and Identification of Potential Molecular Targets	Unknown status	NCT02353429	Phase 2	Toremifene
8	A Phase II Trial of Imatinib for Patients With Aggressive Desmoid Tumor (Aggressive Fibromatosis)	Completed	NCT02495519	Phase 2	Imatinib
9	Phase II Pilot Study Of Moderate Dose Radiotherapy For Inoperable Aggressive Fibromatoses	Completed	NCT00030680	Phase 2
10	Phase II Study to Evaluate Glivec (Imatinib Mesylate) to Induce Progression Arrest in Aggressive Fibromatosis / Desmoid Tumors Not Amenable to Surgical Resection With R0 Intent or Accompanied by Unacceptable Function Loss	Completed	NCT01137916	Phase 2	Imatinib
11	Multicentric Phase I/II Study Evaluating the Efficacy and Toxicity of Imatinib in Adult Patients With Aggressive Fibromatosis That Cannot be Treated by Surgery or Curative Radiotherapy	Completed	NCT00287846	Phase 1, Phase 2	imatinib mesylate
12	Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis	Completed	NCT03966742	Phase 2
13	A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis	Completed	NCT01265030	Phase 1, Phase 2	Sirolimus
14	An Open-label, Multi-center, Phase 2 Study of Denosumab in Subjects With Giant Cell Rich Tumors of Bone	Recruiting	NCT03605199	Phase 2	Denosumab
15	A Safety, Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor, Nirogacestat (PF-03084014) in Children and Adolescents With Progressive, Surgically Unresectable Desmoid Tumors	Recruiting	NCT04195399	Phase 2	Nirogacestat
16	Phase 2, Double-blind, Randomized, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis	Recruiting	NCT05152173	Phase 2
17	A Phase 1/2 Study of Tegavivint (NSC#826393) in Children, Adolescents, and Young Adults With Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors	Recruiting	NCT04851119	Phase 1, Phase 2	Tegavivint
18	DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors	Recruiting	NCT02834013	Phase 2
19	Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis	Active, not recruiting	NCT01981551	Phase 2	PF-03084014
20	Randomized Phase II Trial Evaluating Compliance With Monitoring Conducted Either by a Hospital-based Physician in Person or by a Nurse in Remote Monitoring	Not yet recruiting	NCT05500391	Phase 2
21	Effect of Hydroxyurea as Treatment for Primary Desmoid Tumors in Adults and Children (CHP-914)	Withdrawn	NCT00978146	Phase 2	Hydroxyurea
22	A Pilot Study of Intralesional Injection of Triamcinolone Acetonide for Desmoid Tumors	Completed	NCT03627741	Phase 1	Triamcinolone Acetonide
23	Operative Hysteroscopy for Fibroma by Classic Resection Versus Morcellation: a Ramdomised Study	Unknown status	NCT02406898
24	3-dimensional Versus Conventional Laparoscopy in Patients Undergoing Total Hysterectomy for Benign Disease - A Randomised Clinical Trial	Unknown status	NCT02610985
25	Clinicopathological and Molecular Correlation of Acrochordon in Relation to Human Papillomavirus Infection	Unknown status	NCT00520078
26	Tailored Beta-catenin Mutational Approach in Extra-abdominal Sporadic Desmoids Tumor Patients	Unknown status	NCT02547831
27	A Comparison of Long Term Outcomes Following Total Laparoscopic Hysterectomy and Laparoscopic Supracervical Hysterectomy.	Unknown status	NCT01289314
28	Peripheral Primitive Fibromatosis. Study Evaluating a Simple Initial Monitoring With Search of Scalability Predictive Factors and Registration of Treatments in Case of Progression	Unknown status	NCT01801176
29	A Prospective Analysis of Active Observation in Patients With Desmoid-Type Fibromatosis	Recruiting	NCT04281381
30	The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study	Recruiting	NCT02402244
31	Biomarkers for Tuberous Sclerosis Complex: An International Multicenter Observational Longitudinal Protocol	Active, not recruiting	NCT02654340
32	A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol	Active, not recruiting	NCT00919269
33	Biomarker for Hyaline Fibromatosis Syndrome - An International, Multicenter, Epidemiological Protocol	Active, not recruiting	NCT03196115
34	National Clinical-biological Prospective Cohort of Incident Cases of Aggressive Fibromatosis	Active, not recruiting	NCT02867033
35	The Evaluation of Health-related Quality of Life Issues Experienced by Patients With Desmoid-type Fibromatosis	Enrolling by invitation	NCT04289077
36	Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated With VizAblate® Intrauterine-ultrasound Guided RF Ablation	Terminated	NCT01998854
37	Pilot Investigation of 18F-FES PET/CT Imaging of Desmoid Tumors	Terminated	NCT02374931	Early Phase 1	F-18 16 Alpha-Fluoroestradiol
38	South Miami Hospital Fibroid Registry	Terminated	NCT02362009

Search NIH Clinical Center for Fibroma

Cochrane evidence based reviews: fibroma

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Genetic Tests for Fibroma

Genetic tests related to Fibroma:

#	Genetic test	Affiliating Genes
1	Fibroma ²⁸

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Anatomical Context for Fibroma

Organs/tissues related to Fibroma:

MalaCards : Bone, Ovary, Small Intestine, Uterus, Heart, Skin, Breast

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Publications for Fibroma

Articles related to Fibroma:

(show top 50) (show all 7510)

#	Title	Authors	PMID	Year
1	Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors. ⁵³ ⁶²	Zhao C...Vang R	19033865	2009
2	Loss of the PTCH1 gene locus in cardiac fibroma. ⁵³ ⁶²	Scanlan D...Bridge JA	18329553	2008
3	Mesenchymal-epithelial interactions involving epiregulin in tuberous sclerosis complex hamartomas. ⁵³ ⁶²	Li S...Darling TN	18292222	2008
4	Is loss of heterozygosity at 9q22.3 (PTCH gene) and 19p13.3 (STK11 gene) involved in the pathogenesis of ovarian stromal tumors? ⁵³ ⁶²	Tsuji T...Prat J	16084949	2005
5	Role of the hedgehog/patched signaling pathway in oncogenesis: a new polymorphism in the PTCH gene in ovarian fibroma. ⁵³ ⁶²	Levanat S...Oreskovic S	15659790	2004
6	Origin of stellate giant cells in oral fibrous lesions determined by immunohistochemical expression of vimentin, HHF-35, CD68 and factor XIIIa. ⁵³ ⁶²	Souza LB...Pinto LP	15370129	2004
7	Solitary sclerotic fibroma of skin: a possible link with pleomorphic fibroma with immunophenotypic expression for O13 (CD99) and CD34. ⁵³ ⁶²	Mahmood MN...Lee MW	14744088	2003
8	Ultrastructural and immunohistochemical characterization of the so-called giant multinucleate cells in cutaneous collagenomas. ⁵³ ⁶²	Ramos D...Llombart-Bosch A	12147091	2002
9	Fibroma and inflammatory myofibroblastic tumor of the heart. ⁵³ ⁶²	de Montpreville VT...Dulmet E	11745071	2001
10	S100A6 expression in fibrohistiocytic lesions. ⁵³ ⁶²	Fullen DR...McNutt NS	11401666	2001
11	Two cases of supernumerary ovary: one with large fibroma with Meig's syndrome and the other with endometriosis and cystic change. ⁵³ ⁶²	Kamiyama K...Iwamasa T	11795834	2001
12	Cytokeratin expression in trichoblastic fibroma (small nodular type trichoblastoma), trichoepithelioma and basal cell carcinoma. ⁵³ ⁶²	Yamamoto O...Asahi M	10215762	1999
13	Benign fibromatous tumors of the testis and paratesticular region: a report of 9 cases with a proposed classification of fibromatous tumors and tumor-like lesions. ⁵³ ⁶²	Jones MA...Scully RE	9060599	1997
14	Pleomorphic hamartoma of the subcutis: a lesion with possible myogenous and neural lineages. ⁵³ ⁶²	Shitabata PK...Wick MR	7593822	1995
15	An immunohistochemical study of odontogenic mixed tumours. ⁵³ ⁶²	Yamamoto K...Osaki T	7543314	1995
16	Phenotypic characterisation of stellate and giant cells in giant cell fibroma by immunocytochemistry. ⁵³ ⁶²	Odell EW...Lombardi TL	7523665	1994
17	So-called "immature dentinoma": a case presentation and histological comparison with ameloblastic fibrodentinoma. ⁵³ ⁶²	Takeda Y	8164161	1994
18	Histologic and immunohistochemical evidence for considering ovarian myxoma as a variant of the thecoma-fibroma group of ovarian stromal tumors. ⁵³ ⁶²	Costa MJ...Cohen C	7688213	1993
19	Mesothelial and related neoplasms in children and adolescents: a clinicopathologic and immunohistochemical analysis of eight cases. ⁵³ ⁶²	Coffin CM...Dehner LP	1384016	1992
20	Cytoskeletal gene expression in normal and neoplastic human odontogenic epithelia. ⁵³ ⁶²	Heikinheimo K...Bosch FX	1721670	1991
21	Immunohistochemical analysis for desmin in normal and neoplastic ovarian stromal tissue. ⁵³ ⁶²	Lastarria D...Nuovo GJ	2159271	1990
22	Transformation of Cemento-Ossifying Fibroma into Osteosarcoma after Radiotherapy and Nine Endoscopic Surgeries. ⁶²	Wang Y...Meng J	35575211	2023
23	Juvenile psammomatoid ossifying fibroma in paranasal sinuses: A case report and literature review. ⁶²	Trung NN...Duc NM	36324855	2023
24	Peripheral Ossifying Fibroma and Peripheral Odontogenic Fibroma: Close Relatives or Family? ⁶²	Ide F...Kikuchi K	35524033	2022
25	MDM2 Gene Amplification and Expression of MDM2 and CDK4 are Rare in Ossifying Fibroma of Craniofacial Bones. ⁶²	Bahceci DH...Horvai AE	35546651	2022
26	Ovarian Signet-ring Stromal Tumor: A Morphologic, Immunohistochemical, and Molecular Study of 7 Cases With Discussion of the Differential Diagnosis. ⁶²	Tchrakian N...McCluggage WG	36040033	2022
27	Calcifying aponeurotic fibroma: Radiologic-pathologic analysis of ten cases and review of the literature. ⁶²	Pena-Burgos EM...Pozo-Kreilinger JJ	36371890	2022
28	Unusual Findings in a Patient With Carney Complex due to a Novel PRKAR1A Mutation. ⁶²	Friedrich RE...Zenker M	36456122	2022
29	The rare ventricular arrhythmia recurrence following fibroma resection: Can we predict who is at risk? ⁶²	Motonaga KS	36336301	2022
30	Surgical Management of a Giant Left Ventricular Fibroma in a Newborn. ⁶²	Egunov OA...Yanulevich OS	35502859	2022
31	Desmoplastic fibroma of the left 6th rib in a 35-year-old man: A case report. ⁶²	Zhang K...Zhang J	35691815	2022
32	Chondromyxoid fibroma of the iliac bone: a brief radiological review. ⁶²	Alsford S...Mistry A	36446478	2022
33	Skull base pathology - a diagnostic conundrum. ⁶²	Devakumar H...Ferguson M	34924063	2022
34	Malignant fibroma presenting as a hypoglycemia and coma in a 45-year-old male patient: A case report. ⁶²	Hanif M...Vadiyala MR	36419579	2022
35	Clinical Impact of Cardiac Fibromas. ⁶²	Covington MK...Klarich KW	36055811	2022
36	Complex trigger wrist associated with carpal tunnel syndrome: a case report. ⁶²	Lychagin AV...Ponomarev AB	36371272	2022
37	Management of juvenile trabecular ossifying fibroma of bone of the maxilla in a child: A case report at a tertiary hospital in Northern Tanzania. ⁶²	Nnko KA...Mremi A	36257140	2022
38	A novel technique to repair orbital roof defects: irradiated homologous cadaveric rib (Tutoplast ®) graft in a recurrent frontal sinus ossifying fibroma. ⁶²	Acharya V...Clarke P	36425586	2022
39	Juvenile psammomatoid ossifying fibroma of the maxilla and mandible: A systematic review of published case reports. ⁶²	R C...Dhungel S	36325758	2022
40	Allogeneic Tendon Transplantation for the Treatment of Pathological Patellar Ligament Defect in Children: Technical Note and 4-Year Follow-Up. ⁶²	Zhou M...Yang R	36321600	2022
41	Recurrent FOSL1 rearrangements in desmoplastic fibroblastoma. ⁶²	De Noon S...Flanagan AM	36426824	2022
42	Brown Tumors Belong to the Spectrum of KRAS -driven Neoplasms. ⁶²	Turek D...Baumhoer D	36040039	2022
43	Prevalence of benign bone lesions of the lower extremity in the pediatric spinal disorders: a whole-body imaging study. ⁶²	Yucekul A...Alanay A	35102057	2022
44	Three Cases of Mandibular Ossifying Fibroma in Cattle. ⁶²	de Oliveira Freitas DC...Serakides R	36116887	2022
45	Peripheral Ossifying Fibroma Veiling a Nasopalatine Duct Cyst: An Unusual Concurrence. ⁶²	Popli H...Kamboj M	36452642	2022
46	Endoscopic Transnasal Management of Giant Paediatric Sinonasal Ossifying Fibroma. ⁶²	Eswaran S...Saravanam PK	36452801	2022
47	Oestrogen receptor expression distinguishes non-ossifying fibroma from other giant cell containing bone tumours. ⁶²	Cleven AHG...Bovee JVMG	35612673	2022
48	Ventricular arrhythmias after fibroma resection: Are patients still at risk? ⁶²	El Assaad I...O'Leary ET	36228870	2022
49	Histopathogenesis of bone- and soft-tissue tumor spectrum with USP6 gene rearrangement: multiple partners involved in the tissue repair process. ⁶²	Legrand M...de Pinieux G	36205240	2022
50	A case of death of patient with ovarian fibroma combined with Meigs Syndrome and literature review. ⁶²	Tan N...Zheng H	36253781	2022

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Genes for Fibroma

Genes related to Fibroma (0 elite genes):

(show all 26)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	MALAT1	Metastasis Associated Lung Adenocarcinoma Transcript 1	RNA Gene	150	Experimental evidence: Regulation ³⁷	27101025
2	CDC73	Cell Division Cycle 73	Protein Coding	28.37	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Disorders Publications (show sections)	15070940
3	PTCH1	Patched 1	Protein Coding	22.43	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	16084949 15659790 9071574 (more) 15545745 15688838 18329553
4	VIM	Vimentin	Protein Coding	21.56	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	1721670 7527534 11795834 (more) 12147091 7543314 7523665 15370129 7593822 10638360 1381130 1384016
5	ACTC1	Actin Alpha Cardiac Muscle 1	Protein Coding	21.4	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	18425046 9237180 7688213 (more) 11745071
6	CD34	CD34 Molecule	Protein Coding	18.08	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	14744088
7	F13A1	Coagulation Factor XIII A Chain	Protein Coding	17.25	Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	7523665 11401666
8	DES	Desmin	Protein Coding	16.99	Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	2159271 9060599 7688213 (more) 11745071 7523665 7593822 11795834
9	SERPINA3	Serpin Family A Member 3	Protein Coding	16.82	DISEASES inferred ¹⁴ ¹⁴ GeneCards inferred via : Publications (show sections)
10	S100A1	S100 Calcium Binding Protein A1	Protein Coding	16.56	Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	9237180 11745071 18425046
11	MUC16	Mucin 16, Cell Surface Associated	Protein Coding	16.51	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11795834
12	S100A9	S100 Calcium Binding Protein A9	Protein Coding	15	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11401666
13	TSC1	TSC Complex Subunit 1	Protein Coding	14.91	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	18292222 10534239
14	USP6	Ubiquitin Specific Peptidase 6	Protein Coding	14.53	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
15	CTNNB1	Catenin Beta 1	Protein Coding	14.15	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
16	CALB2	Calbindin 2	Protein Coding	14.09	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	19033865 12409724 15754297 (more) 12808064 18269580
17	NF1	Neurofibromin 1	Protein Coding	13.4	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
18	CD68	CD68 Molecule	Protein Coding	13.26	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
19	SATB2	SATB Homeobox 2	Protein Coding	13.07	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
20	KRT7	Keratin 7	Protein Coding	13.01	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
21	PECAM1	Platelet And Endothelial Cell Adhesion Molecule 1	Protein Coding	12.95	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
22	PGR	Progesterone Receptor	Protein Coding	12.9	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
23	GNAS	GNAS Complex Locus	Protein Coding	12.84	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
24	CD99	CD99 Molecule (Xg Blood Group)	Protein Coding	12.57	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
25	FN1	Fibronectin 1	Protein Coding	12.57	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
26	ESR1	Estrogen Receptor 1	Protein Coding	12.54	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)

Sources

Variations for Fibroma

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Expression for Fibroma

Search GEO for disease gene expression data for Fibroma.

Sources

Pathways for Fibroma

Pathways related to Fibroma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cytoskeletal Signaling ³	11.95	VIM KRT7 DES ACTC1
2	Striated muscle contraction pathway ⁷⁴ Show member pathways Striated Muscle Contraction ⁶⁶	10.67	VIM DES ACTC1
3	Transcription co-factors SKI and SKIL protein partners ⁷⁴	10.1	SATB2 NF1