Fibroma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: FBR054 MIFTS: 47	Fibroma Categories: Cancer diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Fibroma

MalaCards integrated aliases for Fibroma:

Name: Fibroma ¹² ⁷⁷ ³⁰ ⁵⁶ ⁴⁵ ¹⁵ ¹⁷

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0050871

MeSH ⁴⁵ D005350

EFO ¹⁷ EFO_0002424

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Summaries for Fibroma

Disease Ontology : ¹² A connective tissue benign neoplasm composed of fibrous or connective tissues that derives from mesenchymal tissue.

MalaCards based summary : Fibroma is related to chondromyxoid fibroma and fibromatosis. An important gene associated with Fibroma is MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1), and among its related pathways/superpathways are Cytoskeleton remodeling Neurofilaments and Striated Muscle Contraction. The drugs Anesthetics and Anesthetics, Local have been mentioned in the context of this disorder. Affiliated tissues include bone, ovary and skin, and related phenotypes are cellular and cardiovascular system

Wikipedia : ⁷⁷ Fibromas are benign tumors that are composed of fibrous or connective tissue. They can grow in all... more...

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Related Diseases for Fibroma

Diseases related to Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 345)

#	Related Disease	Score	Top Affiliating Genes
1	chondromyxoid fibroma	33.3	ACTC1 COL12A1 DES S100A1 VIM
2	fibromatosis	32.5	ACTC1 CTNNB1 DES VIM
3	birt-hogg-dube syndrome	31.9	CTNNB1 PTCH1
4	cutaneous fibrous histiocytoma	31.9	ACTC1 DES F13A1 SERPINA3 VIM
5	fibrosarcoma	30.8	DES MALAT1 VIM
6	epulis	30.7	DES VIM
7	chondroma	30.2	ACTC1 CTNNB1
8	granular cell tumor	30.2	DES SERPINA3 VIM
9	giant cell tumor	30.1	ACTC1 DES SERPINA3 VIM
10	infantile digital fibromatosis	30.1	DES VIM
11	odontoma	30.1	KRT14 VIM
12	spindle cell sarcoma	30.1	ACTC1 DES VIM
13	inflammatory myofibroblastic tumor	30.1	ACTC1 DES VIM
14	cutaneous leiomyosarcoma	30.0	ACTC1 DES
15	congenital epulis	30.0	CD34 DES VIM
16	pleomorphic liposarcoma	30.0	DES VIM
17	osteoblastoma	30.0	CTNNB1 USP6
18	ameloblastoma	30.0	KRT14 PTCH1 SERPINA3
19	odontogenic myxoma	29.9	SERPINA3 VIM
20	mesenchymal chondrosarcoma	29.9	DES VIM
21	erythema elevatum diutinum	29.9	CD34 F13A1
22	chordoma	29.9	DES S100A1 VIM
23	congenital fibrosarcoma	29.9	ACTC1 DES VIM
24	leiomyosarcoma	29.8	ACTC1 DES S100A1 VIM
25	leiomyoma	29.8	ACTC1 CD34 DES S100A1 VIM
26	liposarcoma	29.7	CD34 DES VIM
27	hemangiopericytoma, malignant	29.6	ACTC1 DES F13A1 VIM
28	carcinosarcoma	29.6	ACTC1 CTNNB1 DES VIM
29	dermatofibrosarcoma protuberans	29.5	ACTC1 CD34 DES F13A1 SERPINA3 VIM
30	fibrous histiocytoma	29.3	ACTC1 DES F13A1 SERPINA3 VIM
31	juvenile ossifying fibroma	12.4
32	ovarian fibroma	12.4
33	ossifying fibroma	12.4
34	discoid fibromas, familial multiple	12.3
35	testicular fibroma	12.2
36	calcifying aponeurotic fibroma	12.2
37	liver fibroma	12.1
38	osteofibrous dysplasia	12.0
39	hyperparathyroidism 2 with jaw tumors	11.9
40	familial adenomatous polyposis 1	11.5
41	basal cell nevus syndrome	11.5
42	terminal osseous dysplasia	11.5
43	leiomyoma, uterine	11.3
44	fibromatosis multiple non ossifying	11.3
45	gigantiform cementoma, familial	11.2
46	skin tag	11.2
47	encephalocraniocutaneous lipomatosis	11.0
48	bladder benign neoplasm	11.0
49	pleural disease	11.0
50	dupuytren contracture	11.0

Graphical network of the top 20 diseases related to Fibroma:

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Symptoms & Phenotypes for Fibroma

MGI Mouse Phenotypes related to Fibroma:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cellular	MP:0005384	9.96	ACTC1 CD34 CDC73 COL12A1 CTNNB1 DES
2	cardiovascular system	MP:0005385	9.92	ACTC1 CDC73 CTNNB1 DES F13A1 PTCH1
3	homeostasis/metabolism	MP:0005376	9.85	ACTC1 CD34 CDC73 CTNNB1 DES F13A1
4	muscle	MP:0005369	9.56	ACTC1 CDC73 COL12A1 CTNNB1 DES PTCH1
5	respiratory system	MP:0005388	9.17	CDC73 CTNNB1 F13A1 KRT14 PTCH1 S100A1

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Drugs & Therapeutics for Fibroma

Drugs for Fibroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 105)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Anesthetics

Phase 4,Phase 3,Phase 2,Not Applicable

Anesthetics, Local

Phase 4,Phase 3,Phase 2

Mifepristone

Approved, Investigational

Phase 2, Phase 3

84371-65-3

55245

Sorafenib

Approved, Investigational

Phase 3

284461-73-0

216239 406563

Miconazole

Approved, Investigational, Vet_approved

Phase 3,Phase 1,Phase 2

22916-47-8

4189

Sirolimus

Approved, Investigational

Phase 3,Phase 1,Phase 2

53123-88-9

46835353 6436030 5284616

Everolimus

Approved

Phase 3,Phase 1,Phase 2

159351-69-6

6442177 70789204

Petrolatum

Approved, Investigational

Phase 2, Phase 3

8009-03-8

Triamcinolone

Approved, Vet_approved

Phase 3,Phase 1

124-94-7

31307

Calcium

Approved, Nutraceutical

Phase 3,Phase 2

7440-70-2

271

Vitamin A

Approved, Nutraceutical, Vet_approved

Phase 3

22737-96-8, 68-26-8, 11103-57-4

9904001 445354

Hormones

Phase 2, Phase 3,Phase 3,Phase 1,Early Phase 1

Hormone Antagonists

Phase 2, Phase 3,Phase 3,Phase 1,Early Phase 1

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 2, Phase 3,Phase 3,Phase 1,Early Phase 1

Contraceptives, Postcoital

Phase 2, Phase 3

Contraceptive Agents

Phase 2, Phase 3

Contraceptives, Oral

Phase 2, Phase 3

Luteolytic Agents

Phase 2, Phase 3

Protein Kinase Inhibitors

Phase 3,Phase 1,Phase 2

Anti-Bacterial Agents

Phase 3,Phase 1,Phase 2

Anti-Infective Agents

Phase 3,Phase 1,Phase 2

Immunosuppressive Agents

Phase 3,Phase 1,Phase 2

Immunologic Factors

Phase 3,Phase 1,Phase 2

Antibiotics, Antitubercular

Phase 3,Phase 1,Phase 2

Antifungal Agents

Phase 3,Phase 1,Phase 2

Anesthetics, General

Phase 3

Calcium, Dietary

Phase 3,Phase 2

Triamcinolone hexacetonide

Phase 3,Phase 1

Anti-Inflammatory Agents

Phase 3,Phase 2,Phase 1

Retinol palmitate

Phase 3

retinol

Phase 3

Triamcinolone diacetate

Phase 3,Phase 1

glucocorticoids

Phase 3,Phase 1

triamcinolone acetonide

Phase 3,Phase 1

Toremifene

Approved, Investigational

Phase 2

89778-26-7

3005573

Denosumab

Approved

Phase 2

615258-40-7

Hydroxyurea

Approved

Phase 2

127-07-1

3657

Aminolevulinic acid

Approved

Phase 2

106-60-5

137

leucovorin

Approved

Phase 2

58-05-9

6006 143

Vinblastine

Approved

Phase 2

865-21-4

13342 241903

Methotrexate

Approved

Phase 2

1959-05-2, 59-05-2

126941

Sulindac

Approved, Investigational

Phase 2

38194-50-2

1548887 5352

Sodium Citrate

Approved, Investigational

Phase 2

68-04-2

Tamoxifen

Approved

Phase 2,Phase 1

10540-29-1

2733526

Ipilimumab

Approved

Phase 2

477202-00-9

nivolumab

Approved

Phase 2

946414-94-4

Adalimumab

Approved

Phase 2

331731-18-1

16219006

Bupivacaine

Approved, Investigational

Phase 2

2180-92-9, 38396-39-3

2474

Paclitaxel

Approved, Vet_approved

Phase 2

33069-62-4

36314

Ibuprofen

Approved

Phase 2

15687-27-1

3672

Interventional clinical trials:

(show top 50) (show all 109)

#	Name	Status	NCT ID	Phase	Drugs
1	Prospective Trial Comparing the Performance Profiles of Two Non-Cross-Linked Porcine Dermal Matrices in Abdominal Wall Reconstruction	Recruiting	NCT02228889	Phase 4
2	Fasciectomy vs Collagenase Injection in Recurrent Dupuytren Disease	Enrolling by invitation	NCT03406338	Phase 4	Collagenase Clostridium Histolyticum
3	Trial Comparing Treatment Strategies in Dupuytren's Contracture	Recruiting	NCT03192020	Phase 4	Collagenase Clostridium Histolyticum 2.9 MG/ML [Xiaflex]
4	Collagenase Injection vs Percutaneous Needle Aponeurotomy for Dupuytren's Disease	Recruiting	NCT03000114	Phase 4	XIAFLEX
5	Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF	Active, not recruiting	NCT02647619	Phase 4	Xiapex
6	Prospective Randomized Trial Between Needle Fasciotomy and Xiapex for Dupuytrens Contracture	Recruiting	NCT02476461	Phase 4	xiapex
7	Retreatment of Recurrent Dupuytren's Contractures	Completed	NCT01498640	Phase 4
8	MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex	Completed	NCT01450397	Phase 4
9	Efficacy and Safety of Xiaflex Injection for Treatment of Dupuytren's Contracture of the Thumb	Completed	NCT01265420	Phase 4
10	Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's Contracture	Terminated	NCT01226121	Phase 4
11	Study of Volume Reduction of Uterine Fibroids After Embolization or Microwave Treatment	Recruiting	NCT02942537	Phase 2, Phase 3
12	Mifepristone to Treat Uterine Fibroids	Terminated	NCT01786226	Phase 2, Phase 3	Oral administration of mifepristone 2.5 mg daily for three months;Oral administration of mifepristone 5 mg daily for three months
13	Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis	Active, not recruiting	NCT02066181	Phase 3	Sorafenib Tosylate
14	Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)	Recruiting	NCT03785964	Phase 3	Nirogacestat oral tablet;Placebo Oral Tablet
15	Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)	Completed	NCT00789828	Phase 3	Everolimus;Placebo
16	Ledderhose Disease: Radiotherapy or Not?	Recruiting	NCT03507010	Phase 3
17	Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's	Recruiting	NCT02725528	Phase 3	collagenase injection
18	Non-US Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease	Completed	NCT00533273	Phase 3
19	Safety and Efficacy Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease	Completed	NCT00528840	Phase 3
20	AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease	Completed	NCT00528424	Phase 3
21	Collagenase in the Treatment of Dupuytrens Disease	Completed	NCT00260429	Phase 3
22	Collagenase and Needle Aponeurotomy: Single Modality Versus Combination Treatment for Dupuytren's Disease	Withdrawn	NCT01776892	Phase 3	Collegenase injection
23	Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures	Completed	NCT01674634	Phase 3
24	Collagenase Option for Reduction of Dupuytren's Contracture in Japan	Completed	NCT01588353	Phase 3	Collagenase Clostridium Histolyticum
25	Administration of Two Injections for Multiple Dupuytren's Contractures	Completed	NCT01407068	Phase 3
26	Treatment Of Dupuytren's Contracture With Collagenase Clostridium Histolyticum Injection (Xiapex)	Completed	NCT01229436	Phase 3	Xiapex
27	Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound Healing	Completed	NCT00931567	Phase 2, Phase 3
28	Effects of Steroid Injection With Percutaneous Needle Aponeurotomy in Dupuytren's Contracture	Completed	NCT00565019	Phase 3	Triamcinolone Acetonide
29	AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's Contracture	Completed	NCT00528606	Phase 3
30	Phase III Randomized Study of Collagenase in Patients With Residual Stage Dupuytren's Disease	Completed	NCT00014742	Phase 3	collagenase
31	Toremifene in Desmoid Tumor: Prospective Clinical Trial and Identification of Potential Molecular Targets	Unknown status	NCT02353429	Phase 2	Toremifene
32	Dupuytren's Disease and Extracorporeal Shockwave Therapy (DupuyShock-2010)	Unknown status	NCT01184586	Phase 2
33	Open Label Immunotherapy of Myoma	Recruiting	NCT03550703	Phase 2
34	Denosumab in Subjects With Giant Cell Rich Tumors of Bone	Recruiting	NCT03605199	Phase 2	Denosumab
35	A Phase 2, Study to Evaluate the Safety and Efficacy Proellex® (Telapristone Acetate) Administered Vaginally in the Treatment of Uterine Fibroids	Completed	NCT02323646	Phase 2	Placebo Comparator;Proellex 6 mg;Proellex 12 mg
36	A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis	Recruiting	NCT01265030	Phase 1, Phase 2	Sirolimus
37	Effect of Hydroxyurea as Treatment for Primary Desmoid Tumors	Withdrawn	NCT00978146	Phase 2	Hydroxyurea
38	Imatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis	Completed	NCT00287846	Phase 1, Phase 2	imatinib mesylate
39	Radiation Therapy in Treating Patients With Aggressive Fibromatoses	Completed	NCT00030680	Phase 2
40	A Trial of Imatinib for Patients With Aggressive Desmoid Tumor (Aggressive Fibromatosis)	Completed	NCT02495519	Phase 2	Imatinib
41	Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis	Active, not recruiting	NCT01981551	Phase 2	PF-03084014
42	Study to Evaluate Imatinib in Desmoid Tumors	Completed	NCT01137916	Phase 2	Imatinib
43	Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex	Recruiting	NCT03363763	Phase 2	Sirolimus 0.2%;Sirolimus 0.4%;Placebo ointment
44	A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor	Not yet recruiting	NCT03802084	Phase 1, Phase 2	vactosertib/imatinib combination
45	Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors	Recruiting	NCT01898416	Phase 2	5-AMINOLEVULINIC ACID (5-ALA), is a non fluorescent prodrug.
46	PAZOPANIB Efficacy and Tolerance in Desmoids Tumors	Recruiting	NCT01876082	Phase 2	PAZOPANIB treatment;Active Comparator: Vinblastine and Methotrexate
47	Vinblastine and Methotrexate in Treating Children With Desmoid Tumors	Completed	NCT00003019	Phase 2	methotrexate;vinblastine sulfate
48	Toremifene in Treating Patients With Desmoid Tumors	Completed	NCT00002595	Phase 2	toremifene
49	Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor	Completed	NCT00068419	Phase 2	tamoxifen citrate;sulindac
50	Nivolumab and Ipilimumab in Treating Patients With Rare Tumors	Recruiting	NCT02834013	Phase 2

Search NIH Clinical Center for Fibroma

Cochrane evidence based reviews: fibroma

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Genetic Tests for Fibroma

Genetic tests related to Fibroma:

#	Genetic test	Affiliating Genes
1	Fibroma ³⁰

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Anatomical Context for Fibroma

MalaCards organs/tissues related to Fibroma:

⁴²

Bone, Ovary, Skin, Heart, Kidney, Tongue, Breast

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Publications for Fibroma

Articles related to Fibroma:

(show top 50) (show all 3019)

#	Title	Authors	Year
1	Sex Cord-stromal Tumors With Steroid Cell Tumor and Fibroma Components: Report of 2 Cases, Including One of Extraovarian Origin. ( 29369920 )	Wong RW...McCluggage WG	2019
2	Management of an extensive equine juvenile ossifying fibroma by rostral mandibulectomy and reconstruction of the mandibular symphysis using String of Pearls plates with cortical and cancellous bone autografts. ( 30370537 )	Ogden NKE...Zedler ST	2019
3	Two-stage surgical treatment for a giant sellar psammomatoid juvenile ossifying fibroma: case report. ( 30611151 )	Twitchell S...Brockmeyer D	2019
4	Electrochemotherapy with cisplatin for the treatment of a non-operable cutaneous fibroma in a cockatiel (Nymphicus hollandicus). ( 30626280 )	Racnik J...Tozon N	2019
5	Fibroma of the Tendon Sheath Arising From the Flexor Digitorum Superficialis Tendon. ( 30680050 )	Jordan MM...Reisler T	2019
6	Stereotactic radiosurgery as a treatment for recurrent ventricular tachycardia associated with cardiac fibroma. ( 30693205 )	Haskova J...Kautzner J	2019
7	Gingival choristoma masquerading as fibroma. ( 30706888 )	Laxmidevi BL...Mahadesh J	2019
8	Skull base juvenile psammomatoid ossifying fibroma: clinical characteristics, treatment and prognosis. ( 30743026 )	Wang K...Wu Z	2019
9	An Unusual Presentation of Ovarian Fibroma Originating from an Autoamputated Ovary. ( 30783589 )	Yazawa H...Imaizumi K	2019
10	Fibroma of the patellar tendon sheath-a rare case in a young boy. ( 30783711 )	Pilania K...Memon FW	2019
11	Non-ossifying fibroma: a RAS-MAPK driven benign bone neoplasm. ( 30809793 )	Bov?e JVMG...Hogendoorn PCW	2019
12	Fibrous Dysplasia and Juvenile Psammomatoid Ossifying Fibroma: A Case of Mistaken Identity. ( 30813749 )	Turin SY...Gosain AK	2019
13	Reconstruction of the Proximal Aspect of the Radius After Desmoplastic Fibroma Resection: A Case Report. ( 30817326 )	Lans J...Lozano-Calder?n S	2019
14	Multimodal radiological imaging of collagenous fibroma arising from the subacromial region in a patient with osteosarcoma: A case report. ( 30847175 )	Murata H...Nishigaki Y	2019
15	Unilateral visual loss resulting from orbital encroachment of an ethmoidal juvenile trabecular ossifying fibroma. ( 30854866 )	Ta NH...Philpott C	2019
16	A case of irritation fibroma. ( 30858793 )	Jiang M...Gu H	2019
17	Juvenile Trabecular Ossifying Fibroma-a Case Report. ( 29887713 )	Seifi S....Mohammadi M.R.	2018
18	Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma. ( 28991228 )	Lee S....Tuckermann J.	2018
19	Chondromyxoid Fibroma of the Metatarsal Bone: A Diagnosis Using Fine Needle Aspiration Biopsy. ( 29403178 )	Dey B....Ray A.	2018
20	Ovarian fibroma with luteinized thecal cells and minor sex cord element: A rare case report. ( 29676374 )	Mathur A....Pant L.	2018
21	Chondromyxoid Fibroma Arising in Craniofacial Sites: A Clinicopathologic Analysis of 25 Cases. ( 29324473 )	Meredith D.M....Jo V.Y.	2018
22	Peripheral Ameloblastic Fibroma of Anterior Maxillary Gingiva Simulating Pyogenic Granuloma. ( 29950270 )	Bajpai M....Vijay P.	2018
23	Uterine fibroid or ovarian fibroma: importance of comprehensive preoperative consent-taking to include unexpected findings with management implications. ( 29437720 )	Kwek L.K....Chern S.M.B.	2018
24	Rare case of a recurrent juvenile ossifying fibroma of the lumbosacral spine. ( 29521580 )	Dalle Ore C.L....Ames C.P.	2018
25	Juvenile Ossifying Fibroma in the Mandible. ( 29963444 )	Khanna J....Ramaswami R.	2018
26	Cardiac Fibroma: An Uncommon Cause of a Fixed Defect on Myocardial Perfusion Imaging. ( 29215416 )	Pittman S....Pampaloni M.H.	2018
27	CT and MR imaging characteristics of histological subtypes of head and neck ossifying fibroma. ( 29595323 )	Kawaguchi M....Matsuo M.	2018
28	Benign Chondromyxoid Fibroma of the Iliac Crest. ( 29385939 )	Johnson G.C....Christensen M.	2018
29	A Case of Juvenile Psammomatoid Ossifying Fibroma on Skull Base. ( 29762329 )	Kim D.Y....Cho J.H.	2018
30	A case report on partial scapulectomy with glenoid preservation for Chondromyxoid fibroma of scapula. ( 29628714 )	Chetia N.P....Borgohain M.	2018
31	Calcifying Aponeurotic Fibroma of the Hallux <sub>A Case Report</sub>. ( 29547027 )	Sheikh R.N....Karlic K.	2018
32	Conservative Management of Ovarian Fibroma in A Case of Gorlin-Goltz Syndrome Comorbid with Endometriosis. ( 29334213 )	Khodaverdi S....Tajbakhsh B.	2018
33	MicroRNA profiling reveals dysregulated microRNAs and their target gene regulatory networks in cemento-ossifying fibroma. ( 29032608 )	Pereira T.D.S.F....Gomez R.S.	2018
34	Late-stage nodular erythema elevatum diutinum mimicking sclerotic fibroma. ( 29068068 )	Shi K.Y....Vandergriff T.	2018
35	Cardiac Fibroma with Ventricular Tachycardia: An Unusual Clinical Presentation of Nevoid Basal Cell Carcinoma Syndrome. ( 30140199 )	Ritter AL...Izumi K	2018
36	Multiple calcifying aponeurotic fibroma: case report and review of the literature. ( 30701881 )	Chaltsev BD...Nikonorova NO	2018
37	Calcifying aponeurotic fibroma: a core biopsy-based diagnosis. ( 30799443 )	Motta F...Magro G	2018
38	Treatment of cryotherapy and orthotopic transplantation following chondromyxoid fibroma of zygomatic bone: A case report. ( 30075574 )	Zhu ZC...Yang WJ	2018
39	Huge chondromyxoid fibroma of the right iliac wing with tremendous soft tissue extensions. ( 30363225 )	Ali HM	2018
40	Surface-type chondromyxoid fibroma in an elderly patient: a case report and literature review. ( 30498967 )	Harrington KA...La Rocca Vieira R	2018
41	Chondromyxoid Fibroma of the Pelvis: Institutional Case Series With a Focus on Distinctive Features. ( 30580642 )	Sono T...James AW	2018
42	Chondromyxoid fibroma with a secondary aneurysmal bone cyst of the distal radius: A case report. ( 30580890 )	Toda Y...Mawatari M	2018
43	Chondromyxoid fibroma of the temporal bone: A case report and review of the literature. ( 30613685 )	Zheng YM...Dong C	2018
44	Letter to the Editor/Comments on "Endometrial cancer after ulipristal acetate for uterine fibroma" by Ignatov et al. Eur J Obstet Gynecol Reprod Biol 2017; Dec;219:134. ( 29287965 )	Chabbert-Buffet N...Fernandez H	2018
45	Pleomorphic fibroma of the skin with MDM2 immunoreactivity: A potential diagnostic pitfall. ( 28981153 )	Tashakori M...Williamson SR	2018
46	Chronic Calf Pain Caused by Fibroma-Induced Chronic Inflammation Around the Tibial and Peroneal Nerves that Was Misdiagnosed as Centralized Neuropathic Pain: A Case Report. ( 29284194 )	Park J...Kim YA	2018
47	Subperiosteal fibroma of the orbit. ( 29303383 )	Rong AJ...Choi CJ	2018
48	Fibroma-like PEComa: A Tuberous Sclerosis Complex-related Lesion. ( 29324470 )	Larque AB...Deshpande V	2018
49	Granular cell tumors of the tongue: fibroma or schwannoma. ( 29329562 )	Musha A...Yokoo S	2018
50	Right atrial fibroma in an adult patient. ( 29336396 )	Heidari A...Faraji R	2018

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Genes for Fibroma

Genes related to Fibroma (0 elite genes):

(show all 15)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	MALAT1	Metastasis Associated Lung Adenocarcinoma Transcript 1	RNA Gene	150	Experimental evidence: Regulation ⁴⁰	27101025
2	CDC73	Cell Division Cycle 73	Protein Coding	40.31	Novoseek inferred ⁵⁶ GeneCards inferred via : Disorders Publications Variants (show sections)	15070940
3	PTCH1	Patched 1	Protein Coding	30.81	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	16084949 15659790 9071574 (more) 15545745 15688838 18329553
4	ACTC1	Actin Alpha Cardiac Muscle 1	Protein Coding	30.38	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	18425046 9237180 7688213 (more) 11745071
5	VIM	Vimentin	Protein Coding	29.42	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	1721670 7527534 11795834 (more) 12147091 7543314 7523665 15370129 7593822 10638360 1381130 1384016
6	F13A1	Coagulation Factor XIII A Chain	Protein Coding	26.38	Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	7523665 11401666
7	DES	Desmin	Protein Coding	25.91	Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	2159271 9060599 7688213 (more) 11745071 7523665 7593822 11795834
8	SERPINA3	Serpin Family A Member 3	Protein Coding	24.82	DISEASES inferred ¹⁵ ¹⁵ GeneCards inferred via : Publications (show sections)
9	CTNNB1	Catenin Beta 1	Protein Coding	21.95	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	MUC16	Mucin 16, Cell Surface Associated	Protein Coding	21.7	Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	11795834
11	USP6	Ubiquitin Specific Peptidase 6	Protein Coding	21.44	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	COL12A1	Collagen Type XII Alpha 1 Chain	Protein Coding	21.3	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	KRT14	Keratin 14	Protein Coding	20.96	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
14	CD34	CD34 Molecule	Protein Coding	16.2	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	14744088
15	S100A1	S100 Calcium Binding Protein A1	Protein Coding	15.64	Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	9237180 11745071 18425046

Sources

Variations for Fibroma

Sources

Expression for Fibroma

Search GEO for disease gene expression data for Fibroma.

Sources

Pathways for Fibroma

Pathways related to Fibroma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cytoskeleton remodeling Neurofilaments ²³ Show member pathways Cytoskeleton remodeling Keratin filaments ²³	11.17	DES KRT14 VIM
2	Striated Muscle Contraction ¹ ⁶⁷	10.66	ACTC1 DES VIM

Sources

GO Terms for Fibroma

Cellular components related to Fibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular exosome	GO:0070062	9.56	ACTC1 COL12A1 CTNNB1 DES KRT14 MUC16
2	blood microparticle	GO:0072562	9.5	ACTC1 F13A1 SERPINA3
3	Z disc	GO:0030018	9.43	CTNNB1 DES S100A1
4	I band	GO:0031674	9.37	ACTC1 S100A1
5	fascia adherens	GO:0005916	9.16	CTNNB1 DES
6	cell periphery	GO:0071944	8.8	CD34 CTNNB1 KRT14

Biological processes related to Fibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of gene expression	GO:0010628	9.67	ACTC1 CD34 CTNNB1 VIM
2	beta-catenin-TCF complex assembly	GO:1904837	9.4	CDC73 CTNNB1
3	renal system development	GO:0072001	9.32	CTNNB1 PTCH1
4	cell fate determination	GO:0001709	9.26	CTNNB1 PTCH1
5	intermediate filament organization	GO:0045109	9.16	DES VIM
6	endodermal cell fate commitment	GO:0001711	8.96	CDC73 CTNNB1
7	muscle filament sliding	GO:0030049	8.8	ACTC1 DES VIM

Molecular functions related to Fibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	structural constituent of cytoskeleton	GO:0005200	9.13	DES KRT14 VIM
2	keratin filament binding	GO:1990254	8.62	KRT14 VIM

Sources

Sources for Fibroma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia