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MCID: FBR016
MIFTS: 21

Fibrosclerosis of Breast

Categories: Reproductive diseases, Cancer diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Fibrosclerosis of Breast

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MalaCards integrated aliases for Fibrosclerosis of Breast:

Name: Fibrosclerosis of Breast 12 15
Fibrosis of the Breast 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:10353
ICD10 33 N60.3
ICD9CM 35 610.3
NCIt 50 C3660
SNOMED-CT 68 29070004
UMLS 73 C0156318
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Summaries for Fibrosclerosis of Breast

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MalaCards based summary : Fibrosclerosis of Breast, also known as fibrosis of the breast, is related to mastitis and diabetic mastopathy. An important gene associated with Fibrosclerosis of Breast is XRCC1 (X-Ray Repair Cross Complementing 1), and among its related pathways/superpathways are DNA Damage and HIF-1-alpha transcription factor network. Affiliated tissues include breast and skin.

Wikipedia : 76 Fibrosclerosis of the breast is most frequently used to mean sclerosing lobular adenosis of the breast.... more...

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Related Diseases for Fibrosclerosis of Breast

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Diseases related to Fibrosclerosis of Breast via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mastitis 9.6
2 diabetic mastopathy 9.6
3 wilms tumor 1 9.2 NPM1 SRY
4 hematologic cancer 9.2 ENG NPM1
5 non-proliferative fibrocystic change of the breast 8.0 ENG NPM1 SRY XRCC1

Graphical network of the top 20 diseases related to Fibrosclerosis of Breast:



Diseases related to Fibrosclerosis of Breast
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Symptoms & Phenotypes for Fibrosclerosis of Breast

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Drugs & Therapeutics for Fibrosclerosis of Breast

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Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Shandong Cancer Hospital Affiliated to Shandong University Recruiting NCT02958033 Phase 3
2 Partial Breast Irradiation (PBI) for Selected Patients With Early Breast Cancer Completed NCT00325598 Phase 1, Phase 2
3 Accelerated Radiation Therapy (ART) to the Breast and Nodal Stations Recruiting NCT02917421 Phase 1, Phase 2
4 Study of Prone Accelerated Breast And Nodal IMRT Active, not recruiting NCT02308488 Phase 1, Phase 2 Radiation
5 Trial Comparing Prone and Supine Intensity-modulated Radiotherapy (IMRT) After Breast-conserving Surgery in Patients With Large Breast Volume at High Risk for Skin Toxicity and Fibrosis Unknown status NCT00887523 Not Applicable
6 Radiation Therapy Followed by Surgery in Treating Patients With Early-Stage Breast Cancer Completed NCT01024582 Not Applicable
7 Partial Breast Irradiation (PBI) for Selected Patients With Early Invasive or Non-Invasive Breast Cancer Active, not recruiting NCT00694577 Not Applicable

Search NIH Clinical Center for Fibrosclerosis of Breast

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Genetic Tests for Fibrosclerosis of Breast

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Anatomical Context for Fibrosclerosis of Breast

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MalaCards organs/tissues related to Fibrosclerosis of Breast:

41
Breast, Skin
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Publications for Fibrosclerosis of Breast

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Articles related to Fibrosclerosis of Breast:

# Title Authors Year
1
Lymphocytic mastitis and fibrosis of the breast in long-standing insulin-dependent diabetics. A histopathologic study on diabetic mastopathy and report of ten cases. ( 9269908 )
1997
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Variations for Fibrosclerosis of Breast

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Expression for Fibrosclerosis of Breast

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Search GEO for disease gene expression data for Fibrosclerosis of Breast.
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Pathways for Fibrosclerosis of Breast

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Pathways related to Fibrosclerosis of Breast according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
DNA Damage 4
11.43 NPM1 XRCC1
2
HIF-1-alpha transcription factor network 1
10.44 ENG NPM1
Sources

GO Terms for Fibrosclerosis of Breast

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Biological processes related to Fibrosclerosis of Breast according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 8.62 ENG XRCC1

Molecular functions related to Fibrosclerosis of Breast according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor binding GO:0008134 8.62 NPM1 SRY
Sources

Sources for Fibrosclerosis of Breast

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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