MCID: FBR001
MIFTS: 31

Fibrous Meningioma

Categories: Cancer diseases, Neuronal diseases
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Aliases & Classifications for Fibrous Meningioma

MalaCards integrated aliases for Fibrous Meningioma:

Name: Fibrous Meningioma 11 53 14 16 71
Fibroblastic Meningioma 11

Classifications:



External Ids:

Disease Ontology 11 DOID:7211
MeSH 43 D008579
NCIt 49 C4330
SNOMED-CT 68 511008
UMLS 71 C0334606

Summaries for Fibrous Meningioma

MalaCards based summary: Fibrous Meningioma, also known as fibroblastic meningioma, is related to hemangioblastoma and neurofibromatosis, type ii. An important gene associated with Fibrous Meningioma is NF2 (NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor), and among its related pathways/superpathways are Signaling by Receptor Tyrosine Kinases and Validated nuclear estrogen receptor beta network. Affiliated tissues include spinal cord, salivary gland and temporal lobe, and related phenotypes are Increased proliferation and neoplasm

Related Diseases for Fibrous Meningioma

Diseases related to Fibrous Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
# Related Disease Score Top Affiliating Genes
1 hemangioblastoma 30.1 S100B MUC1 CD34
2 neurofibromatosis, type ii 29.9 TRAF7 SMARCB1 NF2
3 hemangiopericytoma, malignant 29.9 STAT6 S100B NAB2 MUC1 CD34
4 meninges hemangiopericytoma 29.8 STAT6 NF2 NAB2 CD34
5 mesenchymal cell neoplasm 29.8 STAT6 SMARCB1 NAB2 CD34
6 neurilemmoma 29.7 SMARCB1 S100B NF2 MUC1 CD34
7 wilms tumor 1 29.3 SMARCB1 PGR MUC1 CD34
8 transitional meningioma 28.0 TRAF7 SMARCE1 SMARCB1 POLR2A PGR NF2
9 meningothelial meningioma 27.9 TRAF7 SMARCE1 SMARCB1 POLR2A PGR NF2
10 meningioma, familial 27.8 TRAF7 STAT6 SMARCE1 SMARCB1 S100B PTGDS
11 papillary ependymoma 10.4 S100B NF2
12 supratentorial meningioma 10.3 S100B NF2
13 central nervous system fibrosarcoma 10.3 NF2 CD34
14 epithelioid neurofibroma 10.3 NF2 CD34
15 neurilemmoma of the fifth cranial nerve 10.3 NF2 CD34
16 tuberculum sellae meningioma 10.3 TRAF7 NF2
17 sella turcica neoplasm 10.3 TRAF7 NF2
18 small intestine leiomyoma 10.3 NF2 CD34
19 trigeminal nerve neoplasm 10.3 NF2 CD34
20 colonic lymphangioma 10.3 MUC1 CD34
21 nasal cavity benign neoplasm 10.3 NAB2 CD34
22 clear cell ependymoma 10.3 NF2 MUC1
23 epidural spinal canal neoplasm 10.3 NF2 CD34
24 sarcomatoid renal cell carcinoma 10.3 NF2 CD34
25 petroclival meningioma 10.3 TRAF7 NF2
26 spindle cell thymoma 10.3 NAB2 CD34
27 orbital cancer 10.3 NF2 CD34
28 mucinous tubular and spindle renal cell carcinoma 10.3 MUC1 CD34
29 neurofibroma of the heart 10.3 STAT6 CD34
30 monophasic synovial sarcoma 10.2 NAB2 CD34
31 benign perivascular tumor 10.2 STAT6 CD34
32 glomangioma 10.2 STAT6 CD34
33 myxopapillary ependymoma 10.2 S100B NF2 MUC1
34 cellular ependymoma 10.2 S100B NF2 MUC1
35 neurofibromatosis, type i 10.2 S100B NF2 CD34
36 cerebellopontine angle meningioma 10.2 SMARCE1 NF2
37 intraneural perineurioma 10.2 TRAF7 NF2 CD34
38 glomus tumor 10.2 S100B MUC1 CD34
39 sarcomatoid mesothelioma 10.2 NF2 NAB2
40 full schwannomatosis 10.2 SMARCB1 NF2
41 cystic teratoma 10.2 MUC1 CD34
42 foramen magnum meningioma 10.2 TRAF7 POLR2A NF2
43 posterior pituitary gland neoplasm 10.2 SMARCB1 NF2
44 benign peritoneal mesothelioma 10.2 MUC1 CD34
45 central nervous system angiosarcoma 10.2 SMARCB1 CD34
46 peripheral nerve schwannoma 10.2 SMARCB1 NF2
47 pineal region meningioma 10.2 SMARCB1 NF2
48 testicular fibroma 10.2 STAT6 CD34
49 malignant peripheral nerve sheath tumor 10.2 S100B NF2 CD34
50 schwannomatosis 1 10.2 SMARCB1 NF2

Graphical network of the top 20 diseases related to Fibrous Meningioma:



Diseases related to Fibrous Meningioma

Symptoms & Phenotypes for Fibrous Meningioma

GenomeRNAi Phenotypes related to Fibrous Meningioma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Fibrous Meningioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.91 CD34 KLF4 MUC1 NF2 PGR POLR2A
2 normal MP:0002873 9.76 ARHGAP28 EGFL6 KLF4 MUC1 NAB2 PGR
3 immune system MP:0005387 9.7 ARHGAP28 CD34 FBLN1 KLF4 NF2 PGR
4 integument MP:0010771 9.4 CD34 FBLN1 KLF4 MUC1 NAB2 NF2

Drugs & Therapeutics for Fibrous Meningioma

Search Clinical Trials, NIH Clinical Center for Fibrous Meningioma

Genetic Tests for Fibrous Meningioma

Anatomical Context for Fibrous Meningioma

Organs/tissues related to Fibrous Meningioma:

MalaCards : Spinal Cord, Salivary Gland, Temporal Lobe, Pineal, Brain, Colon, Thyroid

Publications for Fibrous Meningioma

Articles related to Fibrous Meningioma:

(show top 50) (show all 169)
# Title Authors PMID Year
1
Primary Heterotopic Meningioma of Nasal Cavity: Case Report and Literature Review. 62
33215534 2022
2
MRI and CT characteristics of a grade I meningioma with concurrent cribriform plate lysis in a dog. 62
36440542 2022
3
Utility of multiparametric pre-operative magnetic resonance imaging in differentiation of chordoid meningioma from the other histopathological subtypes of meningioma-a retrospective study. 62
33837805 2022
4
Case of primary extracranial meningioma of the maxillary sinus presenting as buccal swelling associated with headache: A case report. 62
35127914 2022
5
[Giant petrosal meningioma invading the fourth ventricle: total removal of a recurrent tumor after eighteen years. Neurosurgical nuances. Case report and literature review]. 62
35758082 2022
6
Atypical evolution of meningiomatosis after discontinuation of cyproterone acetate: clinical cases and histomolecular characterization. 62
34613529 2022
7
Fibroblastic meningioma mimicking an intracerebral hemorrhage: case report. 62
34408888 2021
8
Reasons for Diagnostic Delay of Foot Drop Caused by Parasagittal Meningioma: Two Case Reports. 62
34177539 2021
9
Computerized Tomography-Guided Core-Needle Biopsy of Orbital Space-Occupying Lesions: A Case Series. 62
33796518 2021
10
Venous hypertension caused by a meningioma involving the sigmoid sinus: case report. 62
33731025 2021
11
Meningioma with ring enhancement on MRI: a rare case report. 62
33568080 2021
12
Atypical and Fibrous Meningioma with Differential Cerebral Blood Volume on Magnetic Resonance Imaging: A Case Report. 62
34897170 2021
13
An Infratemporal Meningioma: A Diagnostic Dilemma. 62
33717402 2021
14
Magnetic Resonance Imaging (MRI) Differential Diagnosis of Meningiomas Using ANOVA. 62
34354552 2021
15
Occurrence of Chordoid Glioma With Sodium Ion Metabolism Disorder 5 Years After Meningioma Surgery and Whole-Exome Sequencing: A Case Report and Literature Review. 62
34040630 2021
16
Giant Intraparenchymal Meningioma in a Female Child: Case Report and Literature Review. 62
33658857 2021
17
Primary Extracranial Fibrous Meningioma of the Maxillary Sinus: A Case Report and Literature Review. 62
36237455 2021
18
Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Analysis of Microvascular Permeability in Peritumor Brain Edema of Fibrous Meningiomas. 62
34315157 2021
19
Analysis of the inflammatory tumor microenvironment in meningeal neoplasms. 62
32831157 2020
20
[Glioblastoma Mimicking Meningioma Recurrence: A Case Report]. 62
33051400 2020
21
[Fibrous Meningioma with Ring Enhancement in Cerebellopontine Angle Region:Report of One Case]. 62
32385038 2020
22
Solitary fibrous tumour of cervical spinal cord. 62
32499472 2020
23
Fibrous Meningioma in a Patient with Encephalocraniocutaneous Lipomatosis: A Rare Case with Unique Features. 62
32884367 2020
24
[A Case of Atypical Meningioma with Liver Metastasis at 9 Years after Initial Surgery]. 62
31983690 2020
25
Fibrous Meningioma with Skull Invasion. 62
31831993 2019
26
Meningioma in a Postrenal Transplant Case: More than Meets the Eye. 62
31302277 2019
27
Ventricular Meningiomas: Surgical Strategies and a New Finding That Suggest an Origin From the Choroid Plexus Epithelium. 62
31121376 2019
28
Radiomics and machine learning may accurately predict the grade and histological subtype in meningiomas using conventional and diffusion tensor imaging. 62
30443758 2019
29
Intraparenchymal Meningioma in the Basal Ganglia. 62
31082550 2019
30
Acute Subdural Hemorrhage of a Convexity Meningioma in the Postpartum Period; Case Report and Literature Review. 62
31392235 2019
31
Fourth Ventricular Meningiomas. 62
31004862 2019
32
Differentiation Researches on the Meningioma Subtypes by Radiomics from Contrast-Enhanced Magnetic Resonance Imaging: A Preliminary Study. 62
30831287 2019
33
A rare case of paediatric meningioma masquerading as intra-axial lesion. 62
30647227 2018
34
Meningioma With Tyrosine-Rich Crystalloids: A Case Report and Review of the Literature. 62
28817996 2018
35
Ossified extradural en-plaque meningioma of the cervical spine. 62
29422366 2018
36
The role of three-dimensional pseudo-continuous arterial spin labelling in grading and differentiating histological subgroups of meningiomas. 62
29031810 2018
37
Meningiomas with different histological grade in the same patient: Case report. 62
29390304 2017
38
A Distinctive Pathologic Meningioma Completely without Enhancement and Dural Tail Sign on Imaging Findings. 62
28254600 2017
39
Validation of nuclear STAT6 immunostaining as a diagnostic marker of meningeal solitary fibrous tumor (SFT)/hemangiopericytoma. 62
28128724 2017
40
Aneurysm of azygos anterior cerebral artery associated with falcine meningioma: Case Report and review of the literature. 62
28303205 2017
41
Multiple meningiomas consisting of fibrous meningioma, transitional meningioma, and meningotheliomatous meningioma in one adult patient. 62
26425174 2015
42
Sox10 is superior to S100 in the diagnosis of meningioma. 62
25265429 2015
43
Cystic meningioma. 62
25670784 2015
44
Convexity meningioma associated with depression: a case report. 62
25518538 2014
45
Non-dural-based spinal meningioma : the first case report of a fibrous subtype and a review of the literature. 62
25289128 2014
46
A large intramedullary neurofibroma in the thoracic spinal cord: case report. 62
24418789 2014
47
Marginal zone B-cell lymphoma involving a longstanding fibrous meningioma: an initial manifestation of systemic disease. 62
23850496 2013
48
A tentorial venous hemangioma presenting as an extra-axial mass in the ambient cistern: a case report. 62
23946924 2012
49
Radiation-associated meningiomas in children: clinical, pathological, and cytogenetic characteristics with a critical review of the literature. 62
22900483 2012
50
Wilms tumor-1, claudin-1 and ezrin are useful immunohistochemical markers that help to distinguish schwannoma from fibroblastic meningioma. 62
21909685 2012

Variations for Fibrous Meningioma

Expression for Fibrous Meningioma

Search GEO for disease gene expression data for Fibrous Meningioma.

Pathways for Fibrous Meningioma

Pathways related to Fibrous Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.74 STAT6 S100B POLR2A PGR NAB2
2 10.13 SMARCE1 SMARCB1

GO Terms for Fibrous Meningioma

Cellular components related to Fibrous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 bBAF complex GO:0140092 8.92 SMARCE1 SMARCB1

Biological processes related to Fibrous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell differentiation GO:0045597 9.73 SMARCE1 SMARCB1 NF2
2 DNA-templated transcription elongation GO:0006354 9.5 SMARCB1 NAB2 MUC1
3 paracrine signaling GO:0038001 9.46 PGR CD34
4 DNA-templated transcription GO:0006351 9.26 POLR2A NAB2 MUC1 KLF4
5 positive regulation of histone H4 acetylation GO:0090240 8.92 SMARCB1 MUC1

Sources for Fibrous Meningioma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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