MCID: FSH003
MIFTS: 28

Fish Allergy

Categories: Immune diseases

Aliases & Classifications for Fish Allergy

MalaCards integrated aliases for Fish Allergy:

Name: Fish Allergy 12 15
Allergy to Fish 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0060513
UMLS 71 C0856904

Summaries for Fish Allergy

Disease Ontology : 12 A food allergy triggered by fish.

MalaCards based summary : Fish Allergy, also known as allergy to fish, is related to atlantic cod allergy and atlantic salmon allergy. An important gene associated with Fish Allergy is PVALB (Parvalbumin), and among its related pathways/superpathways are Striated Muscle Contraction and Smooth Muscle Contraction. The drugs Omega 3 Fatty Acid and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and b cells.

Related Diseases for Fish Allergy

Diseases related to Fish Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 atlantic cod allergy 11.9
2 atlantic salmon allergy 11.9
3 carp allergy 11.9
4 zebrafish allergy 11.3
5 rainbow trout allergy 11.3
6 food allergy 10.3
7 papillomatosis, confluent and reticulated 10.2
8 urticaria 10.2
9 drug allergy 10.2 PEDS1 IGHE
10 latex allergy 10.2 PDCL IGHE
11 angioedema 10.2
12 vegetable allergy 10.2 PEDS1 PDCL
13 dermatitis, atopic 10.1
14 nut allergy 10.0 PEDS1 PDCL IGHE
15 wheat allergy 10.0 PEDS1 PDCL IGHE
16 egg allergy 10.0 PEDS1 PDCL IGHE
17 dermatitis 10.0
18 rhinitis 10.0
19 peanut allergy 9.9 PEDS1 PDCL IGHE
20 conjunctival disease 9.9 PEDS1 PDCL
21 snail allergy 9.9 TPM4 TPM2
22 crab allergy 9.9 TPM4 TPM2
23 nose disease 9.9 PEDS1 PDCL
24 ascaris lumbricoides infection 9.8 TPM4 TPM2
25 congenital structural myopathy 9.8 TPM4 TPM2
26 dermal ridges-off-the-end 9.8
27 ige responsiveness, atopic 9.8
28 enterocolitis 9.8
29 allergic rhinitis 9.8
30 asthma-related traits 4 9.8
31 intraocular pressure quantitative trait locus 9.8
32 cyanosis, transient neonatal 9.8
33 c1 inhibitor deficiency 9.8
34 mumps 9.8
35 rickets 9.8
36 diarrhea 9.8
37 primary angle-closure glaucoma 9.8
38 measles 9.8
39 rubella 9.8
40 pthirus pubis infestation 9.8 TPM4 TPM2
41 tomato allergy 9.8 PDCL PDC
42 lice infestation 9.8 TPM4 TPM2
43 myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency 9.7 TPM4 TPM2
44 parasitic ectoparasitic infectious disease 9.7 TPM4 TPM2
45 anisakiasis 9.7 TPM4 TPM2 IGHE
46 crustacean allergy 9.7 TPM4 TPM2 PEDS1
47 orange allergy 9.6 PVALB PDCL PDC
48 timothy grass allergy 9.6 PEDS1 PDCL PDC
49 legume allergy 9.6 PEDS1 PDCL PDC
50 fruit allergy 9.6 PEDS1 PDCL PDC

Graphical network of the top 20 diseases related to Fish Allergy:



Diseases related to Fish Allergy

Symptoms & Phenotypes for Fish Allergy

Drugs & Therapeutics for Fish Allergy

Drugs for Fish Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Omega 3 Fatty Acid Phase 4
2 Anesthetics Phase 2, Phase 3
3 Anti-Retroviral Agents Phase 3
4 Pharmaceutical Solutions Phase 2
5
Hydrocortisone Approved, Vet_approved Early Phase 1 50-23-7 5754
6
Heparin Approved, Investigational Early Phase 1 9005-49-6 46507594 772
7
Hydrocortisone acetate Approved, Vet_approved Early Phase 1 50-03-3
8 Antibodies
9 Immunologic Factors
10 Immunoglobulins
11 Protamines Early Phase 1
12 Hydrocortisone 17-butyrate 21-propionate Early Phase 1
13 Anti-Inflammatory Agents Early Phase 1
14 Hydrocortisone hemisuccinate Early Phase 1
15 calcium heparin Early Phase 1

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 Effect of Fish Oil Monoglycerides on the Omega-3 Index: Pilot Study (IO3-02) Completed NCT03735836 Phase 4
2 Impact of Two Formulations of Fish Oil Monoglycerides on the Modulation of Mitochondrial Functions and Lactate Threshold in Athletes. A Pilot Study Active, not recruiting NCT03915535 Phase 4
3 Protocol for a Randomized, Placebo-Controlled, Double-Blinded Trial to Study the Effects of Supplementary Omega-3 Fatty Acids on Serum C-Reactive Protein Levels Terminated NCT00578578 Phase 4
4 Preoperative Carbohydrate Load and Intraoperative Omega-3 Polyunsaturated Fatty Acids Positively Impacts in Nosocomial Morbidity After CAGB Surgery. A Double-blind Randomized Trial. Completed NCT03017001 Phase 2, Phase 3 intravenous w-3 PUFA
5 Efficacy and Safety of Fish Oil (Omega-3 Fatty Acid) Supplementation With Therapeutic Lifestyle Changes Diet Associated With Lipidic Profile in HIV-positive Patients With Antiretroviral Therapy. Completed NCT02537236 Phase 3
6 A Multinational Phase IIb Study to Investigate the Efficacy and Safety of Subcutaneous Immunotherapy With a Modified Fish- Parvalbumin Given in Single Rising and Maintenance Doses to Subjects Allergic to Fish Completed NCT02382718 Phase 2
7 FAST-Fish -Food Allergy Specific Treatment for Fish Allergy. Completed NCT02017626 Phase 1, Phase 2
8 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Role of Anisakidae and/or Fish Flesh Antigens in Fish Allergies. Completed NCT02666092
9 Allergy Against Different Species of Fish in Children and Adolescents Allergic to Fish Completed NCT02365168
10 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Prevalence of Fish Allergy in Occupational Settings. Completed NCT02661074
11 The Role of Hydrocortisone Per-treatment in Decreasing Side Effects of Protamine Sulfate During Cardiac Surgeries, a Randomized Control Trial. Completed NCT04435912 Early Phase 1 Hydrocortisone 200mg IV
12 Potential Allergens in Wine: Double Blind Placebo-controlled Trial and Basophil Activation Analysis Completed NCT00163735 Administration of wine fined with potential food allergens
13 Introduction of Fish Early in the Complementary Feeding Period to Improve Infant Growth in Samfya District, Luapula Province, Zambia Completed NCT03993860
14 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813
15 Effect of Enteral Supplementation of Omega 3 Fatty Acids on the Quality of Life and Functionality of Patients With Head and Neck Squamous Cell Carcinoma Undergoing Radiotherapy Recruiting NCT03720158

Search NIH Clinical Center for Fish Allergy

Genetic Tests for Fish Allergy

Anatomical Context for Fish Allergy

MalaCards organs/tissues related to Fish Allergy:

40
Testes, Skin, B Cells

Publications for Fish Allergy

Articles related to Fish Allergy:

(show top 50) (show all 153)
# Title Authors PMID Year
1
Basophil Activation Test Based on CD203c Expression in the Diagnosis of Fish Allergy. 61
32400130 2020
2
Collagen - an important fish allergen for improved diagnosis. 61
32389794 2020
3
Clinical Management of Seafood Allergy. 61
31950908 2020
4
Myosin heavy chain, a novel allergen for fish allergy in patients with atopic dermatitis. 61
31209867 2019
5
Contribution of recombinant Parvalbumin Gad c 1 in the diagnosis and prognosis of fish allergy. 61
31530508 2019
6
Fish-derived low molecular weight components modify bronchial epithelial barrier properties and release of pro-inflammatory cytokines. 61
31102986 2019
7
Variability of allergens in commercial fish extracts for skin prick testing. 61
30762884 2019
8
Anaesthetic management of patients with pre-existing allergic conditions: a narrative review. 61
30916009 2019
9
Molecular characterization of B-cell epitopes for the major fish allergen, parvalbumin, by shotgun proteomics, protein-based bioinformatics and IgE-reactive approaches. 61
30974223 2019
10
[Allergy to fish]. 61
30942967 2019
11
Patients Allergic to Fish Tolerate Ray Based on the Low Allergenicity of Its Parvalbumin. 61
30471362 2019
12
What Do We Know About Fish Allergy at the End of the Decade? 61
30741635 2019
13
Characterization of Ras k 1 a novel major allergen in Indian mackerel and identification of parvalbumin as the major fish allergen in 33 Asia-Pacific fish species. 61
29193486 2018
14
Jellyfish ingestion was safe for patients with crustaceans, cephalopods, and fish allergy. 61
29423370 2018
15
Cross-reactivity in fish allergy: A double-blind, placebo-controlled food-challenge trial. 61
28479332 2017
16
Advances on the molecular characterization, clinical relevance, and detection methods of Gadiform parvalbumin allergens. 61
26714098 2017
17
Food Specific IgE as A Biomarker of Oral Immunotherapy Efficacy in Comparison to Double Blind Food Challenge Test. 61
29528585 2017
18
Blocking antibodies induced by immunization with a hypoallergenic parvalbumin mutant reduce allergic symptoms in a mouse model of fish allergy. 61
27876628 2017
19
Occupational fish allergy caused by percutaneous sensitization with α-actinin-3. 61
28386978 2017
20
Kounis syndrome following canned tuna fish ingestion. 61
27997286 2017
21
Allergenicity of bony and cartilaginous fish - molecular and immunological properties. 61
28117510 2017
22
Cross-reactivity to fish and chicken meat - a new clinical syndrome. 61
27344988 2016
23
Hypersensitivity reaction to components of parenteral nutrition in pediatrics. 61
27349487 2016
24
Scombroid syndrome: it seems to be fish allergy but... it isn't. 61
27466827 2016
25
Fish allergy in patients with parvalbumin-specific immunoglobulin E depends on parvalbumin content rather than molecular differences in the protein among fish species. 61
27251554 2016
26
Allergy to fish collagen: Thermostability of collagen and IgE reactivity of patients' sera with extracts of 11 species of bony and cartilaginous fish. 61
27236375 2016
27
Prevalence of fish and shellfish allergy: A systematic review. 61
27613460 2016
28
The amyloid fold of Gad m 1 epitopes governs IgE binding. 61
27597317 2016
29
Scombroid Poisoning: A Practical Approach. 61
27133773 2016
30
Study of the cross-reactivity of fish allergens based on a questionnaire and blood testing. 61
26875665 2016
31
Doctor, can I desensitize my food-allergic child using directly the allergenic molecules? 61
27031674 2016
32
Fish collagen is an important panallergen in the Japanese population. 61
26785247 2016
33
SENSITIZATION PATTERN AND CLINICAL PECULARITIES OF FOOD ALLERGY IN GEORGIA. 61
27249439 2016
34
Tolerability to dogfish in children with fish allergy. 61
26337570 2016
35
Histamine (Scombroid) Fish Poisoning: a Comprehensive Review. 61
25876709 2016
36
Update on the bird-egg syndrome and genuine poultry meat allergy. 61
27340614 2016
37
Prevalence of sensitization to food allergens and challenge proven food allergy in patients visiting allergy centers in Rawalpindi and Islamabad, Pakistan. 61
27563525 2016
38
Peanut and fish allergy due to platelet transfusion in a child. 61
25852036 2015
39
Fish-allergic patients may be able to eat fish. 61
25666551 2015
40
Immunological cross-reactivity between four distant parvalbumins-Impact on allergen detection and diagnostics. 61
25451973 2015
41
Fish and shellfish allergy. 61
26022875 2015
42
A Cross-Reactive Human Single-Chain Antibody for Detection of Major Fish Allergens, Parvalbumins, and Identification of a Major IgE-Binding Epitope. 61
26579717 2015
43
Development of a hypoallergenic recombinant parvalbumin for first-in-man subcutaneous immunotherapy of fish allergy. 61
25765512 2015
44
Eczema in early childhood, sociodemographic factors and lifestyle habits are associated with food allergy: a nested case-control study. 61
25926095 2015
45
Flushing and pruritus secondary to prescription fish oil ingestion in a patient with allergy to fish. 61
25314925 2014
46
Differential IgE binding to isoallergens from Asian seabass (Lates calcarifer) in children and adults. 61
24973736 2014
47
Purification and characterization of parvalbumin isotypes from grass carp (Ctenopharyngodon idella). 61
24866418 2014
48
[Food protein-induced enterocolitis syndrome caused by fish ingestion. A case report]. 61
25158381 2014
49
Fish allergy: in review. 61
23440653 2014
50
[Risk factors for adverse reactions after protamine administration in adult patients undergoing cardiac surgery- a case report and literature review]. 61
25004379 2014

Variations for Fish Allergy

Expression for Fish Allergy

Search GEO for disease gene expression data for Fish Allergy.

Pathways for Fish Allergy

Pathways related to Fish Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.81 TPM4 TPM2
2 10.18 TPM4 TPM2

GO Terms for Fish Allergy

Cellular components related to Fish Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.61 TPM4 TPM2 PVALB PPIC PDCL PDC
2 muscle thin filament tropomyosin GO:0005862 8.62 TPM4 TPM2

Biological processes related to Fish Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.62 TPM4 TPM2

Molecular functions related to Fish Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of muscle GO:0008307 8.62 TPM4 TPM2

Sources for Fish Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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