MCID: FSH003
MIFTS: 30

Fish Allergy

Categories: Immune diseases

Aliases & Classifications for Fish Allergy

MalaCards integrated aliases for Fish Allergy:

Name: Fish Allergy 12 15
Allergy to Fish 70

Classifications:



External Ids:

Disease Ontology 12 DOID:0060513
UMLS 70 C0856904

Summaries for Fish Allergy

Disease Ontology : 12 A food allergy triggered by fish.

MalaCards based summary : Fish Allergy, also known as allergy to fish, is related to food allergy and atlantic cod allergy. An important gene associated with Fish Allergy is PVALB (Parvalbumin), and among its related pathways/superpathways are cGMP-PKG signaling pathway and Dilated cardiomyopathy. The drugs Pharmaceutical Solutions and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and skin.

Wikipedia : 73 Fish allergy is an immune hypersensitivity to proteins found in fish. Symptoms can be either rapid or... more...

Related Diseases for Fish Allergy

Diseases related to Fish Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 food allergy 30.3 PVALB IGHE
2 atlantic cod allergy 11.4
3 atlantic salmon allergy 11.4
4 carp allergy 11.4
5 zebrafish allergy 11.1
6 rainbow trout allergy 11.1
7 papillomatosis, confluent and reticulated 10.2
8 urticaria 10.2
9 angioedema 10.2
10 dermatitis, atopic 10.1
11 nut allergy 10.1 PDCL IGHE
12 wheat allergy 10.1 PDCL IGHE
13 egg allergy 10.1 PDCL IGHE
14 peanut allergy 10.0 PDCL IGHE
15 ige responsiveness, atopic 10.0
16 dermatitis 10.0
17 rhinitis 10.0
18 ascaris lumbricoides infection 9.9 TPM4 TPM2
19 congenital structural myopathy 9.9 TPM4 TPM2
20 parasitic ectoparasitic infectious disease 9.9 TPM4 TPM2
21 tomato allergy 9.9 PDCL PDC
22 anisakiasis 9.8 TPM4 TPM2 IGHE
23 timothy grass allergy 9.8 PDCL PDC
24 dermal ridges-off-the-end 9.8
25 enterocolitis 9.8
26 allergic rhinitis 9.8
27 asthma-related traits 4 9.8
28 intraocular pressure quantitative trait locus 9.8
29 cyanosis, transient neonatal 9.8
30 c1 inhibitor deficiency 9.8
31 mumps 9.8
32 rickets 9.8
33 allergic disease 9.8
34 diarrhea 9.8
35 primary angle-closure glaucoma 9.8
36 measles 9.8
37 rubella 9.8
38 legume allergy 9.8 PDCL PDC
39 fruit allergy 9.8 PDCL PDC
40 crab allergy 9.8 TPM4 TPM2 TPM1
41 crustacean allergy 9.7 TPM4 TPM2 TPM1
42 snail allergy 9.7 TPM4 TPM2 TPM1
43 shrimp allergy 9.7 TPM4 TPM2 TPM1
44 pthirus pubis infestation 9.7 TPM4 TPM2 TPM1
45 orange allergy 9.7 PVALB PDCL PDC
46 lice infestation 9.7 TPM4 TPM2 TPM1
47 apple allergy 9.7 PPIC PDCL PDC
48 nasal cavity disease 9.7 PDCL PDC
49 pollen allergy 9.7 PDCL PDC IGHE
50 respiratory allergy 9.7 PDCL PDC IGHE

Graphical network of the top 20 diseases related to Fish Allergy:



Diseases related to Fish Allergy

Symptoms & Phenotypes for Fish Allergy

Drugs & Therapeutics for Fish Allergy

Drugs for Fish Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Pharmaceutical Solutions Phase 2
2 Immunologic Factors
3 Immunoglobulins
4 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Multinational Phase IIb Study to Investigate the Efficacy and Safety of Subcutaneous Immunotherapy With a Modified Fish- Parvalbumin Given in Single Rising and Maintenance Doses to Subjects Allergic to Fish Completed NCT02382718 Phase 2
2 FAST-Fish -Food Allergy Specific Treatment for Fish Allergy. Completed NCT02017626 Phase 1, Phase 2
3 Potential Allergens in Wine: Double Blind Placebo-controlled Trial and Basophil Activation Analysis Completed NCT00163735 Administration of wine fined with potential food allergens
4 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Role of Anisakidae and/or Fish Flesh Antigens in Fish Allergies. Completed NCT02666092
5 Allergy Against Different Species of Fish in Children and Adolescents Allergic to Fish Completed NCT02365168
6 Protists and Nematodes Fish Parasites: From Their Circulation in Ecosystems to Their Impact on Human Health - Prevalence of Fish Allergy in Occupational Settings. Completed NCT02661074
7 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813

Search NIH Clinical Center for Fish Allergy

Genetic Tests for Fish Allergy

Anatomical Context for Fish Allergy

MalaCards organs/tissues related to Fish Allergy:

40
Bone Marrow, Skin

Publications for Fish Allergy

Articles related to Fish Allergy:

(show top 50) (show all 164)
# Title Authors PMID Year
1
IgE and IgG4 epitopes revealed on the major fish allergen Lat c 1. 61
33423763 2021
2
IgE-mediated fish allergy in pediatric age: Does canned tuna have a chance for tolerance? 61
33605499 2021
3
IgE-Mediated Fish Allergy in Children. 61
33477460 2021
4
A review on food processing and preparation methods for altering fish allergenicity. 61
33307772 2020
5
Development of New White Fish Allergy after Bone Marrow Transplantation from a Non-atopic Donor. 61
33380929 2020
6
Letter to the editor: Study Summary - Randomized Control Trial of Omega-3 Fatty Acid Supplementation for the Treatment of COVID-19 Related Olfactory Dysfunction. 61
33225989 2020
7
Canned tuna tolerance in children with IgE-mediated fish allergy: an allergological and nutritional view. 61
32686923 2020
8
Collagen-An Important Fish Allergen for Improved Diagnosis. 61
32389794 2020
9
IgE reactivity to fish allergens from Pacific cod (Gadus macrocephalus) in atopic dogs. 61
32938440 2020
10
Expanding the allergen repertoire of salmon and catfish. 61
32860256 2020
11
True insulin allergy? Lessons from a case of suspected insulin allergy 61
32822327 2020
12
Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options. 61
32712803 2020
13
Basophil Activation Test Based on CD203c Expression in the Diagnosis of Fish Allergy. 61
32400130 2020
14
Role of Recombinant Parvalbumin Gad c 1 in the Diagnosis and Prognosis of Fish Allergy. 61
31530508 2020
15
Clinical Management of Seafood Allergy. 61
31950908 2020
16
Myosin heavy chain, a novel allergen for fish allergy in patients with atopic dermatitis. 61
31209867 2019
17
Fish-derived low molecular weight components modify bronchial epithelial barrier properties and release of pro-inflammatory cytokines. 61
31102986 2019
18
Variability of allergens in commercial fish extracts for skin prick testing. 61
30762884 2019
19
Anaesthetic management of patients with pre-existing allergic conditions: a narrative review. 61
30916009 2019
20
Molecular characterization of B-cell epitopes for the major fish allergen, parvalbumin, by shotgun proteomics, protein-based bioinformatics and IgE-reactive approaches. 61
30974223 2019
21
[Allergy to fish]. 61
30942967 2019
22
Patients Allergic to Fish Tolerate Ray Based on the Low Allergenicity of Its Parvalbumin. 61
30471362 2019
23
What Do We Know About Fish Allergy at the End of the Decade? 61
30741635 2019
24
Characterization of Ras k 1 a novel major allergen in Indian mackerel and identification of parvalbumin as the major fish allergen in 33 Asia-Pacific fish species. 61
29193486 2018
25
Jellyfish ingestion was safe for patients with crustaceans, cephalopods, and fish allergy. 61
29423370 2018
26
Advances on the molecular characterization, clinical relevance, and detection methods of Gadiform parvalbumin allergens. 61
26714098 2017
27
Cross-reactivity in fish allergy: A double-blind, placebo-controlled food-challenge trial. 61
28479332 2017
28
Food Specific IgE as A Biomarker of Oral Immunotherapy Efficacy in Comparison to Double Blind Food Challenge Test. 61
29528585 2017
29
Blocking antibodies induced by immunization with a hypoallergenic parvalbumin mutant reduce allergic symptoms in a mouse model of fish allergy. 61
27876628 2017
30
Occupational fish allergy caused by percutaneous sensitization with α-actinin-3. 61
28386978 2017
31
Kounis syndrome following canned tuna fish ingestion. 61
27997286 2017
32
Allergenicity of bony and cartilaginous fish - molecular and immunological properties. 61
28117510 2017
33
Cross-reactivity to fish and chicken meat - a new clinical syndrome. 61
27344988 2016
34
Hypersensitivity reaction to components of parenteral nutrition in pediatrics. 61
27349487 2016
35
Allergy to fish collagen: Thermostability of collagen and IgE reactivity of patients' sera with extracts of 11 species of bony and cartilaginous fish. 61
27236375 2016
36
Fish allergy in patients with parvalbumin-specific immunoglobulin E depends on parvalbumin content rather than molecular differences in the protein among fish species. 61
27251554 2016
37
Scombroid syndrome: it seems to be fish allergy but... it isn't. 61
27466827 2016
38
The amyloid fold of Gad m 1 epitopes governs IgE binding. 61
27597317 2016
39
Prevalence of fish and shellfish allergy: A systematic review. 61
27613460 2016
40
Scombroid Poisoning: A Practical Approach. 61
27133773 2016
41
Study of the cross-reactivity of fish allergens based on a questionnaire and blood testing. 61
26875665 2016
42
Doctor, can I desensitize my food-allergic child using directly the allergenic molecules? 61
27031674 2016
43
Fish collagen is an important panallergen in the Japanese population. 61
26785247 2016
44
SENSITIZATION PATTERN AND CLINICAL PECULARITIES OF FOOD ALLERGY IN GEORGIA. 61
27249439 2016
45
Tolerability to dogfish in children with fish allergy. 61
26337570 2016
46
Histamine (Scombroid) Fish Poisoning: a Comprehensive Review. 61
25876709 2016
47
Prevalence of sensitization to food allergens and challenge proven food allergy in patients visiting allergy centers in Rawalpindi and Islamabad, Pakistan. 61
27563525 2016
48
Update on the bird-egg syndrome and genuine poultry meat allergy. 61
27340614 2016
49
Peanut and fish allergy due to platelet transfusion in a child. 61
25852036 2015
50
Fish-allergic patients may be able to eat fish. 61
25666551 2015

Variations for Fish Allergy

Expression for Fish Allergy

Search GEO for disease gene expression data for Fish Allergy.

Pathways for Fish Allergy

Pathways related to Fish Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12 TPM4 TPM2 TPM1
2
Show member pathways
11.7 TPM4 TPM2 TPM1
3 11.27 TPM4 TPM2 TPM1
4 10.99 TPM4 TPM2 TPM1
5 10.36 TPM4 TPM2 TPM1

GO Terms for Fish Allergy

Cellular components related to Fish Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.81 TPM4 TPM2 TPM1 PVALB PPIC PDCL
2 actin cytoskeleton GO:0015629 9.43 TPM4 TPM2 TPM1
3 stress fiber GO:0001725 9.32 TPM4 TPM1
4 actin filament GO:0005884 9.13 TPM4 TPM2 TPM1
5 muscle thin filament tropomyosin GO:0005862 8.8 TPM4 TPM2 TPM1

Biological processes related to Fish Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin filament organization GO:0007015 9.33 TPM4 TPM2 TPM1
2 regulation of G protein-coupled receptor signaling pathway GO:0008277 9.26 PDCL PDC
3 muscle contraction GO:0006936 9.13 TPM4 TPM2 TPM1
4 muscle filament sliding GO:0030049 8.8 TPM4 TPM2 TPM1

Molecular functions related to Fish Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.55 TPM4 TPM2 TPM1 PVALB ENO3
2 protein-containing complex binding GO:0044877 9.54 PVALB PDCL ENO3
3 actin binding GO:0003779 9.5 TPM4 TPM2 TPM1
4 protein heterodimerization activity GO:0046982 9.43 TPM4 TPM2 TPM1
5 actin filament binding GO:0051015 9.13 TPM4 TPM2 TPM1
6 structural constituent of muscle GO:0008307 8.8 TPM4 TPM2 TPM1

Sources for Fish Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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