MCID: FLT007
MIFTS: 15

Flotch Syndrome

Categories: Genetic diseases, Rare diseases, Skin diseases

Aliases & Classifications for Flotch Syndrome

MalaCards integrated aliases for Flotch Syndrome:

Name: Flotch Syndrome 52 58 71
Familial Occurrence of Total Leukonychia, Trichilemmal Cysts and Ciliary Dystrophy with Dominant Autosomal Heredity 52
Leukonychia Totalis-Trichilemmal Cysts-Ciliary Dystrophy Syndrome 58

Classifications:

Orphanet: 58  
Rare skin diseases


External Ids:

MESH via Orphanet 44 C537065
ICD10 via Orphanet 33 L60.8
UMLS via Orphanet 72 C2931411
Orphanet 58 ORPHA2045
UMLS 71 C2931411

Summaries for Flotch Syndrome

MalaCards based summary : Flotch Syndrome, also known as familial occurrence of total leukonychia, trichilemmal cysts and ciliary dystrophy with dominant autosomal heredity, is related to nail disorder, nonsyndromic congenital, 3. Affiliated tissues include skin and eye, and related phenotypes are photophobia and abnormality of the nail

Related Diseases for Flotch Syndrome

Diseases related to Flotch Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 nail disorder, nonsyndromic congenital, 3 10.4

Symptoms & Phenotypes for Flotch Syndrome

Human phenotypes related to Flotch Syndrome:

58 31 (show all 9)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 photophobia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000613
2 abnormality of the nail 58 31 hallmark (90%) Very frequent (99-80%) HP:0001597
3 neoplasm of the skin 58 31 hallmark (90%) Very frequent (99-80%) HP:0008069
4 sparse eyelashes 58 31 hallmark (90%) Very frequent (99-80%) HP:0000653
5 blepharitis 58 31 frequent (33%) Frequent (79-30%) HP:0000498
6 nephrolithiasis 58 31 frequent (33%) Frequent (79-30%) HP:0000787
7 abnormality of the eyelashes 58 Very frequent (99-80%)
8 abnormality of the eyelid 58 Very frequent (99-80%)
9 inflammatory abnormality of the eye 58 Very frequent (99-80%)

Drugs & Therapeutics for Flotch Syndrome

Search Clinical Trials , NIH Clinical Center for Flotch Syndrome

Genetic Tests for Flotch Syndrome

Anatomical Context for Flotch Syndrome

MalaCards organs/tissues related to Flotch Syndrome:

40
Skin, Eye

Publications for Flotch Syndrome

Articles related to Flotch Syndrome:

# Title Authors PMID Year
1
Leukonychia totalis associated with multiple pilar cysts: report of a five-generation family: FLOTCH syndrome? 61
21659070 2011
2
[The FLOTCH syndrome. Familial occurrence of total LeukOnychia, Trichilemmal cysts and Ciliary dystrophy with dominant autosomal Heredity]. 61
3813407 1986

Variations for Flotch Syndrome

Expression for Flotch Syndrome

Search GEO for disease gene expression data for Flotch Syndrome.

Pathways for Flotch Syndrome

GO Terms for Flotch Syndrome

Sources for Flotch Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....