Focal Chorioretinitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Focal Chorioretinitis

MalaCards integrated aliases for Focal Chorioretinitis:

Name: Focal Chorioretinitis ¹² ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Eye diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the eye and adnexa

Disorders of choroid and retina

Chorioretinal inflammation

Focal chorioretinal inflammation

External Ids:

Disease Ontology ¹² DOID:1979

ICD10 ³³ H30.0 H30.00

ICD9CM ³⁵ 363.0 363.00

SNOMED-CT ⁶⁸ 15847003 193433002 193439003 more

UMLS ⁷³ C0154870

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Summaries for Focal Chorioretinitis

MalaCards based summary : Focal Chorioretinitis is related to chorioretinitis and syphilis. An important gene associated with Focal Chorioretinitis is CNGB3 (Cyclic Nucleotide Gated Channel Beta 3), and among its related pathways/superpathways are Phototransduction and Visual Cycle in Retinal Rods. Affiliated tissues include eye.

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Related Diseases for Focal Chorioretinitis

Diseases related to Focal Chorioretinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)

#	Related Disease	Score	Top Affiliating Genes
1	chorioretinitis	30.0	CD40LG SAG
2	syphilis	29.0	CD40LG DDX41
3	peripheral focal chorioretinitis	12.0
4	retinitis pigmentosa 48	10.0	CD40LG SAG
5	panuveitis	9.9	CD40LG SAG
6	cardiovascular syphilis	9.7	CD40LG DDX41
7	tertiary syphilis	9.7	CD40LG DDX41
8	latent syphilis	9.7	CD40LG DDX41
9	congenital syphilis	9.7	CD40LG DDX41
10	iridocyclitis	9.7
11	meningitis	9.7
12	secondary syphilis	9.7	CD40LG DDX41
13	asymptomatic neurosyphilis	9.7	CD40LG DDX41
14	immunodeficiency 17	9.6	CD40LG DDX41
15	retinal disease	9.6	CNGB3 SAG
16	tertiary neurosyphilis	9.6	CD40LG DDX41
17	primary bacterial infectious disease	9.5	CD40LG DDX41
18	hypersensitivity reaction disease	9.5	CD40LG DDX41
19	congenital stationary night blindness	9.5	CNGB3 SAG
20	immune system disease	9.4	CD40LG DDX41
21	behcet syndrome	9.2	CD40LG SAG
22	ewing sarcoma	9.2	CD40LG CNGB3 SAG

Graphical network of the top 20 diseases related to Focal Chorioretinitis:

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Symptoms & Phenotypes for Focal Chorioretinitis

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Drugs & Therapeutics for Focal Chorioretinitis

Search Clinical Trials , NIH Clinical Center for Focal Chorioretinitis

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Genetic Tests for Focal Chorioretinitis

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Anatomical Context for Focal Chorioretinitis

MalaCards organs/tissues related to Focal Chorioretinitis:

⁴¹

Eye

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Publications for Focal Chorioretinitis

Articles related to Focal Chorioretinitis:

#	Title	Authors	Year
1	Bilateral papillitis and unilateral focal chorioretinitis as the presenting features of syphilis. ( 26069511 )	Benson C.E....Do D.V.	2015
2	FOCAL CHORIORETINITIS IN THAILAND. ( 23928678 )	Pathanapitoon K....Rothova A.	2013
3	Meningococcal group B meningitis associated with a focal chorioretinitis. ( 15731773 )	Rathod D....Heath J.D.	2005
4	Focal chorioretinitis and iridocyclitis associated with scleroderma. ( 942839 )	David R....Ivry M.	1976
5	FOCAL CHORIORETINITIS PRODUCED BY ULTRASOUND. ( 14238877 )	Purnell E.W....TANER N.	1964
6	THE PRODUCTION OF FOCAL CHORIORETINITIS BY ULTRASOUND. A PRELIMINARY REPORT. ( 14233719 )	Purnell E.W....HOLASEK E.	1964

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Genes for Focal Chorioretinitis

Genes related to Focal Chorioretinitis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CNGB3	Cyclic Nucleotide Gated Channel Beta 3	Protein Coding	16.15	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	SAG	S-Antigen Visual Arrestin	Protein Coding	15.37	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	DDX41	DEAD-Box Helicase 41	Protein Coding	14.47	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	CD40LG	CD40 Ligand	Protein Coding	14.16	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

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Variations for Focal Chorioretinitis

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Expression for Focal Chorioretinitis

Search GEO for disease gene expression data for Focal Chorioretinitis.

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Pathways for Focal Chorioretinitis

Pathways related to Focal Chorioretinitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Phototransduction ³⁷ Show member pathways Activation of the phototransduction cascade ⁶⁶ Inactivation, recovery and regulation of the phototransduction cascade ⁶⁶ The phototransduction cascade ⁶⁶ Visual signal transduction- Cones ¹ Visual signal transduction- Rods ¹	11.15	CNGB3 SAG
2	Visual Cycle in Retinal Rods ⁶⁴	10.6	CNGB3 SAG

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GO Terms for Focal Chorioretinitis

Cellular components related to Focal Chorioretinitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	photoreceptor outer segment	GO:0001750	8.62	CNGB3 SAG

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