Follicular Lymphoma 1 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Follicular Lymphoma 1

MalaCards integrated aliases for Follicular Lymphoma 1:

Name: Follicular Lymphoma 1 ⁵⁷ ²⁹

Follicular Lymphoma, Susceptibility to, 1 ⁵⁷ ¹³

Lymphoma, Follicular, Type 1 ⁴⁰

Lymphoma, Follicular ⁷³

Follicular Lymphoma ⁵⁹

Fl1 ⁵⁷

Characteristics:

Orphanet epidemiological data:

⁵⁹

follicular lymphoma
Inheritance: Multigenic/multifactorial,Not applicable; Prevalence: 1-5/10000 (Europe),1-9/100000 (France); Age of onset: Adult; Age of death: adult;

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Blood diseases Immune diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Neoplasms

Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue

Follicular lymphoma

Cutaneous follicle centre lymphoma

Diffuse follicle centre lymphoma

Follicular lymphoma grade I

Follicular lymphoma grade II

Follicular lymphoma grade III, unspecified

Follicular lymphoma grade IIIa

Follicular lymphoma grade IIIb

Follicular lymphoma, unspecified

Other types of follicular lymphoma

Orphanet: ⁵⁹

Rare haematological diseases

External Ids:

OMIM ⁵⁷ 613024

Orphanet ⁵⁹ ORPHA545

ICD10 via Orphanet ³⁴ C82.1 C82.2 C82.3 more

UMLS via Orphanet ⁷⁴ C0024301

MESH via Orphanet ⁴⁵ D008224

MedGen ⁴² C2751665

SNOMED-CT via HPO ⁶⁹ 115244002 118600007 188676008 more

UMLS ⁷³ C0024301

Sources

Summaries for Follicular Lymphoma 1

OMIM : ⁵⁷ Follicular non-Hodgkin lymphoma is an indolent B-cell malignancy with an annual incidence exceeding 10,000 cases in the United States (Bohen et al., 2003). One form of susceptibility to follicular lymphoma (FL1) is associated with a region on chromosome 6p21.33. (613024)

MalaCards based summary : Follicular Lymphoma 1, also known as follicular lymphoma, susceptibility to, 1, is related to follicular lymphoma and t-cell/histiocyte rich large b cell lymphoma. An important gene associated with Follicular Lymphoma 1 is BCL10 (B Cell CLL/Lymphoma 10), and among its related pathways/superpathways are Immune response Antigen presentation by MHC class II and Direct p53 effectors. The drugs Cisplatin and Gemcitabine have been mentioned in the context of this disorder. Affiliated tissues include b cells, skin and pancreas, and related phenotypes are lymphoma and lymphedema

Sources

Related Diseases for Follicular Lymphoma 1

Diseases in the Follicular Lymphoma family:

Follicular Lymphoma 1

Diseases related to Follicular Lymphoma 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)

#	Related Disease	Score	Top Affiliating Genes
1	follicular lymphoma	28.6	BCL10 BCL2 BCL6 FL1 IGH
2	t-cell/histiocyte rich large b cell lymphoma	10.0	BCL6 IGH
3	high grade b-cell lymphoma with myc and/ or bcl2 and/or bcl6 rearrangement	9.9	BCL2 BCL6
4	nodal marginal zone b-cell lymphoma	9.9	BCL2 BCL6
5	multicentric castleman disease	9.9	BCL6 IGH
6	intravascular large b-cell lymphoma	9.9	BCL2 BCL6
7	primary mediastinal large b-cell lymphoma	9.8	BCL2 BCL6
8	precursor t-cell acute lymphoblastic leukemia	9.8	BCL10 IGH
9	primary central nervous system lymphoma	9.8	BCL2 BCL6
10	human herpesvirus 8	9.8	BCL2 BCL6
11	syphilis	9.6	BCL2 HLA-DRB1
12	gastric lymphoma	9.5	BCL10 BCL2 BCL6
13	diffuse large b-cell lymphoma	9.5	BCL10 BCL6
14	marginal zone b-cell lymphoma	9.5	BCL10 BCL2 BCL6
15	b-cell lymphomas	9.4	BCL10 BCL2 BCL6
16	mantle cell lymphoma	9.4	BCL2 BCL6 IGH
17	lymphoma	9.2	BCL10 BCL2 BCL6
18	lymphoma, mucosa-associated lymphoid type	9.0	BCL10 BCL2 BCL6 IGH
19	lymphoma, non-hodgkin, familial	8.9	BCL10 BCL2 BCL6 IGH
20	leukemia, chronic lymphocytic	8.9	BCL10 BCL2 BCL6 IGH

Graphical network of the top 20 diseases related to Follicular Lymphoma 1:

Sources

Symptoms & Phenotypes for Follicular Lymphoma 1

Clinical features from OMIM:

613024

Human phenotypes related to Follicular Lymphoma 1:

⁵⁹ ³² (show all 13)

#	Description	Orphanet Frequency	HPO Source Accession
1	lymphoma ⁵⁹ ³²	Very frequent (99-80%)	HP:0002665
2	lymphedema ⁵⁹	Occasional (29-5%)
3	meningitis ⁵⁹	Occasional (29-5%)
4	splenomegaly ⁵⁹	Frequent (79-30%)
5	weight loss ⁵⁹	Very frequent (99-80%)
6	fever ⁵⁹	Very frequent (99-80%)
7	pleural effusion ⁵⁹	Occasional (29-5%)
8	abnormality of the peritoneum ⁵⁹	Occasional (29-5%)
9	lymphadenopathy ⁵⁹	Very frequent (99-80%)
10	fatigue ⁵⁹	Frequent (79-30%)
11	night sweats ⁵⁹	Very frequent (99-80%)
12	mediastinal lymphadenopathy ⁵⁹	Very frequent (99-80%)
13	skin nodule ⁵⁹	Occasional (29-5%)

Sources

Drugs & Therapeutics for Follicular Lymphoma 1

Drugs for Follicular Lymphoma 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Cisplatin

Approved

Phase 2

15663-27-1

84093 441203 2767

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatine

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

2

Gemcitabine

Approved

Phase 2

95058-81-4

60750

Synonyms:

103882-84-4

122111-03-9

2',2'-DFDC

2',2'-DiF-dC

2',2'-difluoro-2'-Deoxycytidine

2',2'-Difluoro-2'-deoxycytidine

2',2'-Difluorodeoxycytidine

2'-Deoxy-.beta.-D-2',2'-difluorocytidine

2'-Deoxy-2',2'-difluorocytidine

2'-Deoxy-2',2''-difluorocytidine-5'-O-monophosphate

2'-Deoxy-2'-difluorocytidine

4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,4R,5R)-3,3-difluoro-4-Hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one

95058-81-4

AB1004842

AC1L1TUQ

C07650

CCRIS 8984

CHEBI:175901

CHEMBL888

CID60750

Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine

D02368

DB00441

DDFC

DFdC

DFDC

DFdCyd

Folfugem

Gamcitabine

Gemcel

Gemcin

Gemcitabin

Gemcitabina

Gemcitabina [INN-Spanish]

gemcitabine

Gemcitabine

Gemcitabine (USAN/INN)

Gemcitabine HCl

Gemcitabine hydrochloride

Gemcitabine stereoisomer

Gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer

Gemcitabine, (beta-D-threo-pentafuranosyl)-isomer

Gemcitabine, (D-threo-pentafuranosyl)-isomer

Gemcitabinum

Gemcitabinum [INN-Latin]

GemLip

Gemtro

Gemzar

Gemzar (hydrochloride)

GEO

HMS2089P10

HSDB 7567

Inno-D07001

LS-59139

LY 188011

LY188011

LY-188011

NCGC00168784-01

NChemBio.2007.10-comp25

nchembio.573-comp7

nchembio.90-comp2

NSC 613327

NSC613327

TL8005979

UNII-B76N6SBZ8R

Zefei

ZINC18279854

3

Pancrelipase

Approved, Investigational

Phase 2

53608-75-6

4

Sorafenib

Approved, Investigational

Phase 2

284461-73-0

216239 406563

Synonyms:

284461-73-0

4-(4-((((4-chloro-3-(Trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide

4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide

4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate

4-(4-(3-(4-chloro-3-Trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate

4-(4-{3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide

4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide

4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide

4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE

AB1004622

AC-1674

AC1L50CF

BAX

BAY 439006

BAY 43-9006

BAY 43-9006 (free base)

BAY 43-9006 tosylate salt

BAY 54-9085 (tosylate salt)

BAY-43-0006

BAY43-9006

BAY-43-9006

BAY-54-9085

Bio-0100

BRD-K23984367-001-01-8

CHEBI:47228

CHEBI:50924

CHEMBL1336

CID216239

D08524

DB00398

DB07438

EN002709

I06-0856

K00597a

Kinome_766

LS-186067

LS-187021

LS-187788

MolPort-003-850-270

N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcar bamoyl)-4-pyridyloxy)phenyl)urea

N-(4-chloro-3-(Trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea

N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea

N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea

NCGC00167488-01

nchembio.117-comp17

Nexavar

NSC-724772

NSC747971

sorafenib

Sorafenib

Sorafenib (INN)

Sorafenib [INN]

Sorafenib N-oxide

Sorafenib tosylate

sorafenibum

Sorafenibum

STK627350

UNII-9ZOQ3TZI87

ZINC01493878

5

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 2

59-30-3

6037

Synonyms:

(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

01769_FLUKA

2d0k

33609-88-0

36653-55-1 (mono-potassium salt)

59-30-3

6484-89-5 (mono-hydrochloride salt)

AC-11682

AC1L1LNX

Acfol (Spain)

Acide folique

Acide folique [INN-French]

Acido folico

Acido folico [INN-Spanish]

Acidum folicum

Acidum folicum [INN-Latin]

Acifolic

AI3-26387

AKOS000503224

Antianemia factor

Apo-Folic

ARONIS014410

b9, Vitamin

BIDD:ER0563

BIDD:GT0641

BIF0608

bmse000299

BPBio1_000654

BSPBio_000594

BSPBio_002338

C00504

C20H20N6O6

CAS-59-30-3

CCRIS 666

CHEBI:27470

CHEMBL1622

CID6037

CPD000471860

Cytofol

D00070

DB00158

DivK1c_000494

Dosfolat b activ

Dosfolat B activ

EINECS 200-419-0

F0043

F7876_SIAL

F7876_SIGMA

F8758_SIGMA

F8798_SIAL

F8890_SIGMA

Facid

Factor U

FOL

Folacid

Folacin

Folaemin

Folaemin [Netherlands]

Folan

Folasic (Australia)

Folate

Folbal

Folcidin

Folcidin (VAN)

Folcysteine

Foldine

Foldine [France]

Folettes

Foliamin

Folic

folic acid

Folic acid

Folic acid (JP15/USP/INN)

Folic acid (TN)

Folic acid [BAN:INN:JAN]

Folic acid [INN:BAN:JAN]

Folic acid dihydrate

Folic acid, (D)-isomer

Folic acid, (DL)-isomer

Folic acid, calcium salt (1:1)

Folic acid, monopotassium salt

Folic acid, monosodium salt

Folic acid, potassium salt

Folic acid, sodium salt

Folicet

Folicet (TN)

Folico

Folico (Italy)

Folina

Folina (Italy)

Folipac

Folsaeure

Folsan

Folsaure

Folsav

Folvite

Folvron

Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L

HMS1921D20

HMS2092N17

HMS501I16

HSDB 2002

IDI1_000494

Incafolic

InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s

KBio1_000494

KBio2_001861

KBio2_004429

KBio2_006997

KBio3_001558

KBioGR_002222

KBioSS_001861

Kyselina listova

Kyselina listova [Czech]

Liver lactobacillus casei factor

Liver Lactobacillus casei factor

LS-2157

Millafol

Mission prenatal

Mittafol

MLS001304016

MLS001335861

MolPort-004-285-551

N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid

N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamate

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid

N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-Pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

NCGC00016265-01

NCGC00142391-01

nchembio.108-comp10

Nifolin

Nifolin [Denmark]

NINDS_000494

Novofolacid

Novofolacid [Canada]

N-Pteroyl-L-glutamate

N-Pteroyl-L-glutamic acid

NSC 3073

PGA

PGA (VAN)

Prestwick_230

Prestwick3_000627

PteGlu

Pteroylglutamate

Pteroylglutamic acid

Pteroyl-L-glutamate

Pteroyl-L-glutamic acid

Pteroyl-L-monoglutamate

Pteroyl-L-monoglutamic acid

Pteroylmonoglutamate

Pteroylmonoglutamic acid

SAM002264616

SDCCGMLS-0066738.P001

Serum Folate Level

SMP2_000137

SMR000471860

SPBio_001357

Spectrum_001381

SPECTRUM1502020

Spectrum2_001459

Spectrum3_000749

Spectrum4_001751

Spectrum5_000602

UNII-935E97BOY8

Usaf cb-13

Vitamin B11

Vitamin b9

Vitamin B9

Vitamin Bc

Vitamin BC

Vitamin be

Vitamin Be

Vitamin m

Vitamin M

6

Niacin

Approved, Investigational, Nutraceutical

Phase 2

59-67-6

938

Synonyms:

3 Pyridinecarboxylic acid

3-Carboxylpyridine

3-carboxypyridine

3-Carboxypyridine

3-Pyridinecarboxylate

3-Pyridinecarboxylic acid

3-Pyridylcarboxylate

3-Pyridylcarboxylic acid

Acide nicotinique

Acide Nicotinique

acido Nicotinico

Acido nicotinico

Acidum nicotinicum

Acidum Nicotinicum

Akotin

Aluminum salt, niacin

Anti-pellagra vitamin

Apelagrin

beta-Pyridinecarboxylate

beta-Pyridinecarboxylic acid

b-Pyridinecarboxylate

b-Pyridinecarboxylic acid

Daskil

Efacin

Enduracin

Hydrochloride, niacin

Induracin

Linic

Lithium nicotinate

m-Pyridinecarboxylate

m-Pyridinecarboxylic acid

M-Pyridinecarboxylic Acid

Niac

Niacin

Niacin aluminum salt

Niacin ammonium salt

Niacin calcium salt

Niacin cobalt (2+) salt

Niacin copper (2+) salt

Niacin hydrochloride

Niacin iron (2+) salt

Niacin lithium salt

Niacin lithium salt, hemihydrate

Niacin magnesium salt

Niacin manganese (2+) salt

Niacin potassium salt

Niacin sodium salt

Niacin tartrate

Niacin tosylate

Niacin zinc salt

Niacine

Niacor

Nicacid

Nicamin

Nicangin

nico 400

nico-400

Nico400

Nicobid

Nicocap

Nicodelmine

Nicolar

Niconacid

Nicosan 3

nico-Span

Nicotinate

Nicotinate, lithium

Nicotinic Acid

Nicotinipca

Nicyl

Nikotinsaeure

Nyclin

P.P. factor

Pellagra preventive factor

Pellagrin

Pelonin

Potassium salt, niacin

PP Factor

Pyridine-b-carboxylate

Pyridine-b-carboxylic acid

Pyridine-beta-carboxylate

Pyridine-beta-carboxylic acid

Pyridine-β-carboxylate

pyridine-β-carboxylic acid

Pyridine-β-carboxylic acid

slo-Niacin

Sodium salt, niacin

Tartrate, niacin

Tosylate, niacin

Vitamin b3

Vitamin B3

Wampocap

β-pyridinecarboxylate

β-pyridinecarboxylic acid

7

Nicotinamide

Approved, Investigational, Nutraceutical

Phase 2

98-92-0

936

Synonyms:

.beta.-Pyridinecarboxamide

11032-50-1

123574-63-0

1yc5

3 Pyridinecarboxamide

37321-14-5

3-Carbamoylpyridine

3-Pyridinecarboxamide

3-Pyridinecarboxylic acid amide

47865U_SUPELCO

55600-01-6

63748-44-7

72340_FLUKA

72340_SIGMA

72347_FLUKA

78731-47-2

98-92-0

A186B02E-6C70-4E54-9739-79398D439AAA

AC1L1ACZ

AC1Q4ZFV

AC-907/25014114

Acid amide

AI3-02906

Amid kyseliny nikotinove

Amid kyseliny nikotinove [Czech]

Amide PP

Aminicotin

Amixicotyn

Amnicotin

Astra brand OF niacinamide

Astra Brand of Niacinamide

Austrovit PP

b 3, Vitamin

B 3, Vitamin

b3, Vitamin

B3, Vitamin

BB_NC-2290

Benicot

beta-Pyridinecarboxamide

bmse000281

b-Pyridinecarboxamide

C00153

C6H6N2O

CCRIS 1901

CHEBI:17154

CHEMBL1140

CID936

CPD000058212

D00036

D009536

DB02701

DEA No. 1405

Delonin amide

Dipegyl

Dipigyl

EINECS 202-713-4

EINECS 234-265-0

Endobion

Enduramide

Factor pp

Factor PP

Hansamid

HMS2052M21

HMS2090B05

HMS2093H03

HSDB 1237

I02-1741

I02-2250

InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9

Inovitan PP

Jenapharm brand OF niacinamide

Jenapharm Brand of Niacinamide

Jenapharm, Nicotinsaureamid

Jenapharm, nicotinsäureamid

LS-2051

m-(Aminocarbonyl)pyridine

Mediatric

Merck brand OF niacinamide

Merck Brand of Niacinamide

MLS000069714

MolMap_000061

MolPort-001-783-876

N0078

N0636_SIGMA

N2142_SIGMA

N3376_SIGMA

N5535_SIAL

NAM

Nandervit-N

NCGC00093354-03

NCGC00093354-04

nchembio.154-comp4

nchembio.73-comp6

Niacevit

Niacin

niacin - Vitamin B3

niacinamide

Niacinamide

Niacinamide (USP)

Niacinamide [USAN]

Niacinamide astra brand

Niacinamide Astra Brand

Niacinamide jenapharm brand

Niacinamide Jenapharm Brand

Niacinamide merck brand

Niacinamide Merck Brand

Niacinamide pharmagenix brand

Niacinamide Pharmagenix Brand

Niacinamide, Nicotinic acid amide, Nicotinamide

Niacotinamide

Niamide

Niavit PP

Nicamide

Nicamina

Nicamindon

Nicasir

Nicobion

Nicofort

Nicogen

Nicomidol

Nicosan 2

Nicosylamide

Nicota

Nicotamide

Nicotilamide

Nicotililamido

Nicotinamid

Nicotinamida

Nicotinamida [INN-Spanish]

nicotinamide

Nicotinamide

Nicotinamide (JP15/INN)

Nicotinamide (Niacinamide)

Nicotinamide, niacin, vitamin B3

Nicotinamide-carbonyl-14C

Nicotinamidum

Nicotinamidum [INN-Latin]

Nicotinate amide

Nicotine acid amide

Nicotine amide

Nicotinic acid amide

Nicotinic amide

Nicotinsaeureamid

Nicotinsaureamid

Nicotinsaureamid [German]

Nicotinsaureamid Jenapharm

Nicotinsäureamid jenapharm

Nicotol

Nicotylamide

Nicotylamidum

Nicovel

Nicovit

Nicovitina

Nicovitol

Nicozymin

Nictoamide

Nikasan

Nikazan

niko-Tamin

Niko-tamin

Nikotinamid

Nikotinsaeureamid

Nikotinsaeureamid [German]

Niocinamide

Niozymin

NSC 13128

NSC13128

NSC27452

Papulex

Pelmin

Pelmine

Pelonin amide

Pharmagenix brand OF niacinamide

Pharmagenix Brand of Niacinamide

PP-Faktor

Propamine a

pyridine-3-carboxamide

Pyridine-3-carboxylic acid amide

S1899_Selleck

SAM001246860

Savacotyl

SGCUT00176

SMR000058212

to_000073

UNII-25X51I8RD4

Vi-nicotyl

Vi-Nicotyl

Vi-noctyl

Vitamin B

Vitamin B (VAN)

Vitamin b 3

Vitamin B 3

Vitamin b3

Vitamin H1

vitamin PP

Vitamin PP

Witamina PP

WLN: T6NJ CVZ

ZINC00005878

β-pyridinecarboxamide

8

Antibodies

Phase 2

9

Antibodies, Monoclonal

Phase 2

10

Immunoglobulins

Phase 2

11

Anti-Infective Agents

Phase 2

12

Antimetabolites

Phase 2

13

Antimetabolites, Antineoplastic

Phase 2

14

Antiviral Agents

Phase 2

15

Immunosuppressive Agents

Phase 2

16

Micronutrients

Phase 2

17

Nicotinic Acids

Phase 2

18

pancreatin

Phase 2

19

Protein Kinase Inhibitors

Phase 2

20

Trace Elements

Phase 2

21

Vitamin B Complex

Phase 2

22

Vitamins

Phase 2

23

Folate

Nutraceutical

Phase 2

24

Vitamin B3

Nutraceutical

Phase 2

25

Vitamin B9

Nutraceutical

Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Clinical Comparison of RPDs Retained by Conical and Galvanoformed Double Crowns.	Unknown status	NCT00176215	Phase 4
2	Consolidation Treatment With Y90-Ibritumomab Tiuxetan After R-CHOP Induction in High Risk Patients According to Follicular Lymphoma International Prognostic Index (FLIPI) With Follicular Lymphoma	Unknown status	NCT00722930	Phase 2	Y90 Ibritumomab Tiuxetan
3	Metastatic Advanced Pancreas Sorafenib	Unknown status	NCT00758381	Phase 2	Sorafenib 400 mg po bid, continuously;Gemcitabina, Cisplatino

Search NIH Clinical Center for Follicular Lymphoma 1

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :

ibritumomab tiuxetan

Sources

Genetic Tests for Follicular Lymphoma 1

Genetic tests related to Follicular Lymphoma 1:

#	Genetic test	Affiliating Genes
1	Follicular Lymphoma 1 ²⁹	BCL10

Sources

Anatomical Context for Follicular Lymphoma 1

MalaCards organs/tissues related to Follicular Lymphoma 1:

⁴¹

B Cells, Skin, Pancreas, T Cells

Sources

Publications for Follicular Lymphoma 1

Articles related to Follicular Lymphoma 1:

#	Title	Authors	Year
1	A rare composite lymphoma: follicular and in situ mantle cell. ( 27103006 )	MarA--Jimenez P....SA!nchez-GarcA-a J.	2016
2	Diffuse large B-cell lymphoma/follicular lymphoma arising in a background of IgG4-related pachymeningitis. ( 24247630 )	Lightfoot N....Kalnins R.	2013
3	Clinicopathologic analysis of peripheral T-cell lymphoma, follicular variant, and comparison with angioimmunoblastic T-cell lymphoma: Bcl-6 expression might affect progression between these disorders. ( 22586046 )	Miyoshi H....Ohshima K.	2012
4	Genetic and molecular genetic studies in the diagnosis of B-cell lymphomas I: mantle cell lymphoma, follicular lymphoma, and Burkitt's lymphoma. ( 12733111 )	Campo E.	2003

Sources

Genes for Follicular Lymphoma 1

Genes related to Follicular Lymphoma 1 (6 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	BCL10	B Cell CLL/Lymphoma 10	Protein Coding	500	Pathogenic ⁶ Genetic Tests ²⁹
2	IGH	Immunoglobulin Heavy Locus	Protein Coding	350	Gene fusion ⁵⁹
3	BCL6	B Cell CLL/Lymphoma 6	Protein Coding	350	Gene fusion ⁵⁹
4	BCL2	BCL2, Apoptosis Regulator	Protein Coding	350	Gene fusion ⁵⁹
5	FL1	Follicular Lymphoma, Susceptibility To, 1	Genetic Locus	50	Susceptibility factor ⁵⁷
6	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	25	Susceptibility factor ⁵⁹

Sources

Variations for Follicular Lymphoma 1

ClinVar genetic disease variations for Follicular Lymphoma 1:

⁶

(show all 12)

#	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1	BCL10	NM_003921.4(BCL10): c.427_428dupTT (p.Glu145Leufs)	duplication	Pathogenic	rs587776632	GRCh37	Chromosome 1, 85733584: 85733585
2	BCL10	NM_003921.4(BCL10): c.427_428dupTT (p.Glu145Leufs)	duplication	Pathogenic	rs587776632	GRCh38	Chromosome 1, 85267901: 85267902
3	BCL10	NM_003921.4(BCL10): c.231dupA (p.Gly78Argfs)	duplication	Pathogenic	rs587776633	GRCh37	Chromosome 1, 85736416: 85736416
4	BCL10	NM_003921.4(BCL10): c.231dupA (p.Gly78Argfs)	duplication	Pathogenic	rs587776633	GRCh38	Chromosome 1, 85270733: 85270733
5	BCL10	NM_003921.4(BCL10): c.525_541del17 (p.Val176Asnfs)	deletion	Pathogenic	rs587776634	GRCh37	Chromosome 1, 85733471: 85733487
6	BCL10	NM_003921.4(BCL10): c.525_541del17 (p.Val176Asnfs)	deletion	Pathogenic	rs587776634	GRCh38	Chromosome 1, 85267788: 85267804
7	BCL10	NM_003921.4(BCL10): c.410delA (p.Asn137Ilefs)	deletion	Pathogenic	rs587776635	GRCh37	Chromosome 1, 85733602: 85733602
8	BCL10	NM_003921.4(BCL10): c.410delA (p.Asn137Ilefs)	deletion	Pathogenic	rs587776635	GRCh38	Chromosome 1, 85267919: 85267919
9	BCL10	NM_003921.4(BCL10): c.398dupT (p.Ser134Leufs)	duplication	Pathogenic	rs587776636	GRCh37	Chromosome 1, 85733614: 85733614
10	BCL10	NM_003921.4(BCL10): c.398dupT (p.Ser134Leufs)	duplication	Pathogenic	rs587776636	GRCh38	Chromosome 1, 85267931: 85267931
11	BCL10	NM_003921.4(BCL10): c.635_637delAAG (p.Glu212del)	deletion	Pathogenic	rs587776637	GRCh37	Chromosome 1, 85733375: 85733377
12	BCL10	NM_003921.4(BCL10): c.635_637delAAG (p.Glu212del)	deletion	Pathogenic	rs587776637	GRCh38	Chromosome 1, 85267692: 85267694

Sources

Expression for Follicular Lymphoma 1

Search GEO for disease gene expression data for Follicular Lymphoma 1.

Sources

Pathways for Follicular Lymphoma 1

Pathways related to Follicular Lymphoma 1 according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Immune response Antigen presentation by MHC class II ²² Show member pathways G-protein signaling N-RAS regulation pathway ²² IL-22 Pathway ⁶⁴ Immune response IL-22 signaling pathway ²²	11.6	BCL2 HLA-DRB1
2	Direct p53 effectors ¹	11.52	BCL2 BCL6
3	DNA Damage Response (only ATM dependent) ¹	11.38	BCL2 BCL6
4	Interleukin-4 and 13 signaling ⁶⁶	11.31	BCL2 BCL6
5	TCR signaling in naive CD4+ T cells ¹ Show member pathways TCR signaling in naive CD8+ T cells ¹	11.19	BCL10 HLA-DRB1
6	Tuberculosis ³⁷	11.05	BCL10 BCL2 HLA-DRB1
7	NF-kappa B signaling pathway ³⁷	10.93	BCL10 BCL2

Sources

GO Terms for Follicular Lymphoma 1

Biological processes related to Follicular Lymphoma 1 according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	immune system process	GO:0002376	9.43	BCL10 BCL6 HLA-DRB1
2	negative regulation of cell growth	GO:0030308	9.37	BCL2 BCL6
3	cell morphogenesis	GO:0000902	9.32	BCL2 BCL6
4	B cell differentiation	GO:0030183	9.16	BCL2 BCL6
5	regulation of apoptotic process	GO:0042981	9.13	BCL10 BCL2 BCL6
6	positive regulation of B cell proliferation	GO:0030890	8.62	BCL2 BCL6

Molecular functions related to Follicular Lymphoma 1 according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protease binding	GO:0002020	8.62	BCL10 BCL2

Sources

Sources for Follicular Lymphoma 1

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia

Follicular Lymphoma 1

Aliases & Classifications for Follicular Lymphoma 1

MalaCards integrated aliases for Follicular Lymphoma 1:

Characteristics:

Orphanet epidemiological data:

Classifications:

External Ids:

Summaries for Follicular Lymphoma 1

Related Diseases for Follicular Lymphoma 1

Diseases in the Follicular Lymphoma family:

Diseases related to Follicular Lymphoma 1 via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Follicular Lymphoma 1:

Symptoms & Phenotypes for Follicular Lymphoma 1

Clinical features from OMIM:

Human phenotypes related to Follicular Lymphoma 1:

Drugs & Therapeutics for Follicular Lymphoma 1

Drugs for Follicular Lymphoma 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 73 / NDF-RT 51 :

Genetic Tests for Follicular Lymphoma 1

Genetic tests related to Follicular Lymphoma 1:

Anatomical Context for Follicular Lymphoma 1

MalaCards organs/tissues related to Follicular Lymphoma 1:

Publications for Follicular Lymphoma 1

Articles related to Follicular Lymphoma 1:

Genes for Follicular Lymphoma 1

Genes related to Follicular Lymphoma 1 (6 elite genes):

Variations for Follicular Lymphoma 1

ClinVar genetic disease variations for Follicular Lymphoma 1:

Expression for Follicular Lymphoma 1

Pathways for Follicular Lymphoma 1

Pathways related to Follicular Lymphoma 1 according to GeneCards Suite gene sharing:

GO Terms for Follicular Lymphoma 1

Biological processes related to Follicular Lymphoma 1 according to GeneCards Suite gene sharing:

Molecular functions related to Follicular Lymphoma 1 according to GeneCards Suite gene sharing:

Sources for Follicular Lymphoma 1

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :