Folliculitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: FLL008 MIFTS: 46	Folliculitis Categories: Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Folliculitis

MalaCards integrated aliases for Folliculitis:

Name: Folliculitis ¹² ⁵⁴ ⁴³ ¹⁵ ¹⁷ ⁷¹

Classifications:

MalaCards categories:
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4409

MeSH ⁴³ D005499

NCIt ⁴⁹ C94408

SNOMED-CT ⁶⁷ 13600006

EFO ¹⁷ EFO_1000702

UMLS ⁷¹ C0016436

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Summaries for Folliculitis

MalaCards based summary : Folliculitis is related to eosinophilic pustular folliculitis and exanthem, and has symptoms including exanthema An important gene associated with Folliculitis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are ERK Signaling and Innate Immune System. The drugs Ketoconazole and Retapamulin have been mentioned in the context of this disorder. Affiliated tissues include skin, neutrophil and testes, and related phenotypes are Weakly decreased NFAT1-GFP nuclear translocation and digestive/alimentary

Wikipedia : ⁷⁴ Folliculitis is the infection and inflammation of one or more hair follicles. The condition may occur... more...

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Related Diseases for Folliculitis

Diseases related to Folliculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 531)

#	Related Disease	Score	Top Affiliating Genes
1	eosinophilic pustular folliculitis	35.1	PTGDR2 IFNG
2	exanthem	31.1	IFNG CD4 CCR6
3	dermatitis	31.0	IL5 IL4 IFNG CCR6 CCL11
4	dermatophytosis	30.8	DEFB4A CD4 CCR6
5	hypereosinophilic syndrome	30.7	IL5 IL4 IL2RA IFNG CCL5 CCL11
6	ige responsiveness, atopic	30.7	IL5 IL4 IFNG
7	herpes zoster	30.6	IFNG FCGR3A CD4 CCR6
8	chickenpox	30.5	IL4 IFNG CD4 CCR6
9	erythema multiforme	30.5	IL5 IL4 IFNG GNLY
10	acute graft versus host disease	30.5	IL4 IL2RA IFNG
11	candidiasis	30.5	IL4 IFNG DEFB4A CCR6
12	follicular mucinosis	30.4	MBTPS2 LPP CD4
13	scabies	30.4	CD4 CCR6 CCL11
14	cutaneous leishmaniasis	30.4	IL5 IL4 IFNG
15	contact dermatitis	30.4	IL5 IL4 IFNG CD4
16	orofacial granulomatosis	30.3	IL4 IFNG CCL5
17	acquired immunodeficiency syndrome	30.2	IL2RA IFNG FCGR3A CD4 CCR6
18	pilonidal sinus	30.2	IL2RA CD4
19	eczema herpeticum	30.2	IL4 IFNG CCR6
20	tropical spastic paraparesis	30.1	IL2RA IFNG CCL5
21	syphilis	30.1	IFNG CD4 CCR6
22	meningitis	30.1	IL5 IL4 IFNG CCL5
23	osteomyelitis	30.1	IL4 IFNG CCL5
24	eosinophilic pneumonia	30.1	IL5 IL4 CCL5 CCL11
25	cutaneous t cell lymphoma	30.1	IL5 IL4 IL2RA IFNG CCR6
26	langerhans cell histiocytosis	30.1	IFNG CD1A CCR6
27	histiocytosis	30.1	IFNG CD1A CCR6
28	cellulitis	30.1	IL5 IL4 IFNG DEFB4A CD4 CCR6
29	bullous pemphigoid	30.1	IL5 IL4 CCL5 CCL11
30	bronchitis	30.1	IL5 IL4 CCL5 CCL11
31	interstitial lung disease	30.0	IL5 IL4 IFNG CCL5
32	hyper ige syndrome	30.0	IL4 IFNG CCR6 CCL11
33	extrinsic allergic alveolitis	30.0	IL2RA CCR6 CCL5
34	conjunctivitis	30.0	PTGDR2 IL5 IL4 IFNG CCL11
35	graves' disease	29.9	IL4 IL2RA IFNG CCL5
36	strongyloidiasis	29.9	IL5 IFNG CD4 CCL11
37	proteasome-associated autoinflammatory syndrome 1	29.9	IL5 IL4 IFNG CCL5 CCL11
38	rhinitis	29.9	IL5 IL4 IFNG CCL5 CCL11
39	allergic rhinitis	29.9	IL5 IL4 IFNG CCL5 CCL11
40	immune deficiency disease	29.9	IL4 IL2RA IFNG FCGR3A CD4 CCR6
41	blepharitis	29.8	MBTPS2 IL4 CD4 CCR6
42	pulmonary eosinophilia	29.8	IL5 IL4 CCR6 CCL5 CCL11
43	blepharoconjunctivitis	29.7	IL4 CD4
44	systemic scleroderma	29.7	IL4 IFNG CD4 CCR6
45	meningoencephalitis	29.7	IL4 CD4 CCR6 CCL5
46	lichen planus	29.7	IL4 IFNG DEFB4A CD1A CCL5
47	allergic hypersensitivity disease	29.7	IL5 IL4 IFNG CD4 CCR6 CCL5
48	bacterial infectious disease	29.7	IFNG FCGR3A DEFB4A CD4 CCR6
49	mycosis fungoides	29.6	IL5 IL4 IL2RA IFNG CD1A CCR6
50	adult t-cell leukemia	29.6	IL2RA CD4 CCR6

Graphical network of the top 20 diseases related to Folliculitis:

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Symptoms & Phenotypes for Folliculitis

UMLS symptoms related to Folliculitis:

exanthema

GenomeRNAi Phenotypes related to Folliculitis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Weakly decreased NFAT1-GFP nuclear translocation	GR00359-A	8.92	CCR6 CD1E IL10RB MBTPS2

MGI Mouse Phenotypes related to Folliculitis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	digestive/alimentary	MP:0005381	9.76	CD4 EGF IFNG IL10RA IL10RB IL2RA
2	hematopoietic system	MP:0005397	9.7	CCL11 CCL5 CCR6 CD4 IFNG IL10RA
3	immune system	MP:0005387	9.44	CCL11 CCL5 CCR6 CD160 CD4 EGF

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Drugs & Therapeutics for Folliculitis

Drugs for Folliculitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 74)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Ketoconazole

Approved, Investigational

Phase 4

65277-42-1

47576

Retapamulin

Approved

Phase 4

224452-66-8

6918462

Cephalexin

Approved, Investigational, Vet_approved

Phase 4

15686-71-2

27447

Clindamycin

Approved, Vet_approved

Phase 4

18323-44-9

29029

Anti-Infective Agents

Phase 4

Anti-Bacterial Agents

Phase 4

methicillin

Phase 4

Clindamycin phosphate

Phase 4

Clindamycin palmitate

Phase 4

Clotrimazole

Approved, Vet_approved

Phase 2, Phase 3

23593-75-1

2812

Miconazole

Approved, Investigational, Vet_approved

Phase 2, Phase 3

22916-47-8

4189

Cytochrome P-450 Enzyme Inhibitors

Phase 2, Phase 3

Hormone Antagonists

Phase 2, Phase 3

Hormones

Phase 2, Phase 3

Antifungal Agents

Phase 2, Phase 3

Cytochrome P-450 CYP3A Inhibitors

Phase 2, Phase 3

glucocorticoids

Phase 2, Phase 3

Anti-Inflammatory Agents

Phase 2, Phase 3

Respiratory System Agents

Phase 2, Phase 3

Anti-Asthmatic Agents

Phase 2, Phase 3

Dermatologic Agents

Phase 2, Phase 3

Anti-Infective Agents, Local

Phase 2, Phase 3

Gentamicins

Phase 2, Phase 3

Beclomethasone

Phase 2, Phase 3

4419-39-0

20469

Zinc

Approved, Investigational

Phase 2

7440-66-6

32051

Zinc oxide

Approved

Phase 2

1314-13-2

Loperamide

Approved

Phase 2

53179-11-6

3955

Loratadine

Approved, Investigational

Phase 2

79794-75-5

3957

Cetuximab

Approved

Phase 2

205923-56-4

56842117 2333

Phylloquinone

Approved, Investigational

Phase 2

84-80-0

Tomato

Approved

Phase 2

Lycopene

Approved, Investigational

Phase 2

502-65-8

53477748

Panitumumab

Approved, Investigational

Phase 2

339177-26-3

50070211

Betamethasone

Approved, Vet_approved

Phase 2

378-44-9

9782

Menadione

Approved, Nutraceutical

Phase 2

58-27-5

4055

Menaquinone

Investigational

Phase 2

1182-68-9

Indirubin

Investigational

Phase 2

479-41-4

Antidiarrheals

Phase 2

Pharmaceutical Solutions

Phase 2

Gastrointestinal Agents

Phase 2

Erlotinib Hydrochloride

Phase 2

183319-69-9

176871

Mitogens

Phase 2

Hemostatics

Phase 2

Antifibrinolytic Agents

Phase 2

Vitamin K

Phase 2

naphthoquinone

Phase 2

Vitamin K 3

Phase 2

Coagulants

Phase 2

Carotenoids

Phase 2

Antioxidants

Phase 2

Interventional clinical trials:

(show all 23)

#	Name	Status	NCT ID	Phase	Drugs
1	An Open-Label, Proof of Concept Study to Determine the Safety and Efficacy of Ketoconazole 2% Foam in the Treatment of Pityrosporum Folliculitis	Completed	NCT00824863	Phase 4	ketoconazole 2% foam
2	Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection	Completed	NCT01126268	Phase 4	Retapamulin (Altabax)
3	Randomized Clinical Trial of Wound Packing Following Incision and Drainage of Superficial Skin Abscesses in the Pediatric Emergency Department	Completed	NCT00746109	Phase 4
4	Comparison of Cephalexin Versus Clindamycin in the Empiric, Outpatient Treatment of Suspected Staphylococcal Cutaneous Infections in the Era of Community-associated Methicillin-resistant Staphylococcus Aureus (CA-MRSA)	Completed	NCT00352612	Phase 4	clindamycin;cephalexin
5	Isolation and Comparative Efficacy of the Combination of beclometasona0, 025% + Gentamicin 0.1% + Clotrimazole 1% Topical Dermatological Cream of GLENMARK PHARMACEUTICALS, in Patients Infected With Acne	Suspended	NCT01244256	Phase 2, Phase 3	Clotrimazole + Gentamicin + Beclomethasone;Clotrimazole + Gentamicin
6	Xia Shi Surgical Treatment for Eczema Multi-center Clinical Research	Unknown status	NCT02517957	Phase 2	Furoic acid loperamide hydrochloride cream;Mullite ointment;3% boric acid solution;Zine oxide
7	Phase II Multicentric Study About Preventive Treatment of Folliculitis Induced by the EGF-R Inhibitors in Patients With Metastatic Colorectal Cancer and Treated by Cetuximab or With Non-small-cell Lung Carcinoma Treated by Erlotinib	Completed	NCT00910676	Phase 2	Diprosone
8	Placebo-controlled Trial Investigating the Effect of Vitamin K3-lotion for the Treatment of Cetuximab Induced Folliculitis	Completed	NCT01094444	Phase 2
9	Efficacy and Safety of Topical Indigo Naturalis in Treating Atopic Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Trial	Completed	NCT02669888	Phase 2	Indigo naturalis ointment;Placebo
10	Determination of the Efficacy and Safety of Psirelax in the Relief of the Disease in Psoriasis	Completed	NCT01000714	Phase 2	Psirelax
11	Double-blind, Phase II Study to Assess the Effectiveness of Lycopene vs Placebo to Reduce Skin Toxicity in Patients With Colorectal Carcinoma Treated With Panitumumab	Recruiting	NCT03167268	Phase 2	Lycopene
12	Validation of a Novel Composite of Skin Biomarkers as a Primary Outcome Measure for Evaluating the Safety of Treatments for Atopic Dermatitis: a Randomized Controlled Trial (Phase 2) Comparing the Effects of Crisaborole 2% Ointment to Betamethasone Valerate 0.1% Cream on Skin Structure and Function in Participants With Atopic Dermatitis.	Not yet recruiting	NCT04194814	Phase 2	crisaborole (2%) ointment;betamethasone valerate 0.1% cream
13	Prospective, Controlled Study of the Efficacy of NdYag for Acne Keloidalis Nuchae	Unknown status	NCT00757315		Topical corticosteroid alone
14	The Preventive Effect of Topical EGF Cream for Dermatologic Adverse Events Related to EGFR Inhibitors	Unknown status	NCT03051880		Repair Control EGF®;Cream without rhEGF
15	The Therapeutic Effect of Topical EGF Cream for Dermatologic Adverse Events Related to EGFR Inhibitors	Unknown status	NCT03047863		Repair Control EGF®;Cream without rhEGF
16	Role of Staphylococcus Aureus on Folliculitis Decalvans. A Comparative Bacteriological Study.	Completed	NCT02157688
17	PCR (Polymerase Chain Reaction) Assay for Diagnosis of Sarcoptes Scabiei	Completed	NCT02254564
18	Comparison of Malassezia Spp Proportions in Inflammatory and Non Inflammatory Facial Acne Vulgaris Lesions	Completed	NCT04367584
19	An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus Infection in Soldiers: a Controlled Trial	Completed	NCT00289588		Mupirocin (drug)
20	A Multicenter, Prospective Study to Evaluate CLn® BodyWash As An Adjunctive Therapy in Pediatric Subjects With Moderate to Severe, Staphylococcus Aureus Colonized Atopic Dermatitis	Completed	NCT01714245
21	Assessment of the Effect of Platelet Rich Plasma on the Healing of Operated Sacrococcygeal Pilonidal Sinus by Open Method	Completed	NCT04430413
22	Effectiveness of Vitamin D Supplementation to Reduce Injury and Illness in the UK Armed Forces With Specific Reference to Stress Fracture Risk Reduction	Recruiting	NCT03963128
23	The Role of Trichoscopy in the Preliminary Diagnosis of Immunobollous Diseases	Not yet recruiting	NCT03478072

Search NIH Clinical Center for Folliculitis

Cochrane evidence based reviews: folliculitis

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Genetic Tests for Folliculitis

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Anatomical Context for Folliculitis

MalaCards organs/tissues related to Folliculitis:

⁴⁰

Skin, Neutrophil, Testes, Lung, Bone, T Cells, Bone Marrow

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Publications for Folliculitis

Articles related to Folliculitis:

(show top 50) (show all 2251)

#	Title	Authors	PMID	Year
1	Involvement of granulysin-producing T cells in the development of superficial microbial folliculitis. ⁶¹ ⁵⁴	Oono T...Iwatsuki K	15149502	2004
2	Localization of human beta-defensin-2 and human neutrophil peptides in superficial folliculitis. ⁵⁴ ⁶¹	Oono T...Iwatsuki K	12534631	2003
3	Role of Th2 cytokines, RANTES and eotaxin in AIDS-associated eosinophilic folliculitis. ⁶¹ ⁵⁴	Amerio P...Sauder DN	11501668	2001
4	Improved telangiectasia and reduced recurrence rate of rosacea after treatment with 540 nm-wavelength intense pulsed light: A prospective randomized controlled trial with a 2-year follow-up. ⁶¹	Luo Y...Zhou N	32346416	2020
5	Dermatologic conditions in Down syndrome: A single-center retrospective chart review. ⁶¹	Rork JF...Belazarian L	32519435	2020
6	Eosinophilic pustular folliculitis on the vulva of a patient with cervical cancer. ⁶¹	Mikoshiba A...Okuyama R	32173885	2020
7	Cutaneous leishmaniasis: a pathological study of 360 cases with special emphasis on the contribution of immunohistochemistry and polymerase chain reaction to diagnosis. ⁶¹	Cardozo RS...Tardio JC	32578232	2020
8	Dermatomal necrotizing infundibular crystalline folliculitis following herpes zoster in a patient on PD-1 inhibitor therapy. ⁶¹	Fischer AS...Rubin AI	32428371	2020
9	Mycobacterium chelonae infection mimicking Demodex folliculitis. ⁶¹	Gibson M...Daniel BS	31675449	2020
10	Eosinophilic Dermatoses: Recognition and Management. ⁶¹	Marzano AV...Genovese G	32394361	2020
11	[Risk factors associated with acne keloidalis nuchae, in black subjects: A case-control study]. ⁶¹	Saka B...Pitche P	32081453	2020
12	The investigation of the amounts and expressions of epidermal growth factor, epidermal growth factor receptor, and epidermal growth factor receptor gene polymorphisms in acne vulgaris. ⁶¹	Aydingoz IE...Yenmis G	32421896	2020
13	Cutaneous Larva Migrans Presenting with Folliculitis. ⁶¹	Lander M...Walker SL	32383433	2020
14	Perforating folliculitis triggered by bevacizumab administration. ⁶¹	Maruyama A...Katoh N	32463526	2020
15	A Case of Persistent Beard Folliculitis. ⁶¹	Larrondo J...Gosch M	32416178	2020
16	Aminolevulinic acid photodynamic therapy for folliculitis decalvans: A case report. ⁶¹	Lin X...Zhu X	32233085	2020
17	Successful treatment of refractory folliculitis decalvans with secukinumab. ⁶¹	Ismail FF...Sinclair R	31646619	2020
18	Response to 'Folliculitis decalvans-like pustular plaques on the limbs sparing the scalp'. ⁶¹	Thakur V...Dass Radotra B	32196637	2020
19	Oral treatment with/without topical treatment vs topical treatment alone in Malassezia Folliculitis patients: A systematic review and meta-analysis. ⁶¹	Chaitidis N...Kyriazopoulou M	32319163	2020
20	Anxiety, Depression, and Suicidal Ideation amongst Patients with Facial Dermatoses (Acne, Rosacea, Perioral Dermatitis, and Folliculitis) in Lithuania. ⁶¹	Lukaviciute L...Zouboulis CC	32252051	2020
21	Two is better than one: The combined effects of glycolic acid and salicylic acid on acne-related disorders. ⁶¹	Wiegmann D...Haddad L	32250551	2020
22	Prevalence and cutaneous comorbidities of hidradenitis suppurativa in the German working population. ⁶¹	Kirsten N...Augustin M	32322958	2020
23	Dupilumab for the Treatment of Atopic Dermatitis in an Austrian Cohort-Real-Life Data Shows Rosacea-Like Folliculitis. ⁶¹	Quint T...Bangert C	32344789	2020
24	[Acute generalized pustular bacterid followed by Sweet's syndrome and erythema nodosum]. ⁶¹	Marzolf G...Lipsker D	31812362	2020
25	A novel TRAF3IP2 variant causing familial scarring alopecia with mixed features of discoid lupus erythematosus and folliculitis decalvans. ⁶¹	Nemer G...Kurban M	32350852	2020
26	An update on pityrosporum folliculitis in Singapore from a single tertiary care dermatological centre. ⁶¹	Yong AM...Tan CL	32349197	2020
27	Eosinophilic folliculitis of the scalp associated with PD-1/PDL1 inhibitors. ⁶¹	Rossi A...Carlesimo M	32281235	2020
28	Lichenoid folliculitis in facial lichen planus pigmentosus - a clue to frontal fibrosing alopecia? ⁶¹	Miteva M...Goldberg LJ	32301154	2020
29	Recalcitrant and recurrent bacterial folliculitis during anti-IL 17 therapy in a psoriatic patient. ⁶¹	Sacchelli L...Bardazzi F	30019574	2020
30	Histopathologic and dermoscopic features of 42 cases of folliculitis decalvans: a case series. ⁶¹	Uchiyama M...Tsuboi R	32272176	2020
31	Hookworm: An Uncommon Cause of Folliculitis in Travelers. ⁶¹	Saenz Aguirre A...Fatsini Blanch V	31982086	2020
32	Association between eosinophilic folliculitis and follicular mucinosis. A case series. ⁶¹	Munoz-Aceituno E...Dauden E	32323302	2020
33	Treatment of Trametinib-Associated Folliculitis Eruption With Fluconazole. ⁶¹	Steele C...Googe P	32267472	2020
34	Malassezia: a case of coexisting pityriasis versicolor and Malassezia folliculitis. ⁶¹	Choi E...Aw D	29926112	2020
35	Granulomatous mural folliculitis in a dog treated with ciclosporin and methotrexate. ⁶¹	Panzuti P...Pin D	31908101	2020
36	Secondary syphilis presenting as diffused folliculitis. ⁶¹	Adas A...Chaby G	31774197	2020
37	Antifungal activity of different essential oils against Malassezia pathogenic species. ⁶¹	Donato R...Bilia AR	31704415	2020
38	Characterization of infections and hypogammaglobulinemia treated with the combination of pertuzumab and trastuzumab. ⁶¹	Mortimer JE...Yuan Y	31641845	2020
39	Granulomatous Skin Diseases in a Tertiary Care Portuguese Hospital: A 10-Year Retrospective Study. ⁶¹	Queiros CS...Filipe P	32079818	2020
40	Folliculitis decalvans is characterized by a persistent, abnormal subepidermal microbiota. ⁶¹	Matard B...Reygagne P	30907453	2020
41	Folliculitis Decalvans and Lichen Planopilaris Phenotypic Spectrum-A Series of 7 New Cases With Focus on Histopathology. ⁶¹	Egger A...Miteva M	31855586	2020
42	Diagnostic evaluation of a point-of-care test for culture and microbial susceptibility testing in canine dermatological infections in clinical practice. ⁶¹	Perego R...Proverbio D	32367959	2020
43	Molecular epidemiology, in vitro susceptibility and exoenzyme screening of Malassezia clinical isolates. ⁶¹	Li W...Fan YM	32068525	2020
44	Analysis of cases managed by dermatological service in the Chinese peacekeeping level 1+ medical treatment facility in Lebanon, 2018-2019. ⁶¹	Wang X...Yu Q	32111673	2020
45	Long-term safety and efficacy of delgocitinib ointment, a topical Janus kinase inhibitor, in adult patients with atopic dermatitis. ⁶¹	Nakagawa H...Nagata T	31820485	2020
46	Clinical features and treatment of epidermal growth factor inhibitor-related late-phase papulopustular rash. ⁶¹	Tohyama M...Nishina T	31803963	2020
47	Synthetic hair reactions and treatment of complications: Case reports. ⁶¹	Triwongwaranat D...Thuangtong R	32060980	2020
48	Gram-negative infections in patients with folliculitis decalvans: a subset of patients requiring alternative treatment. ⁶¹	Samrao A...Mirmirani P	32239885	2020
49	Critical synthesis of available data in Malassezia folliculitis and a systematic review of treatments. ⁶¹	Vlachos C...Saunte DM	32012377	2020
50	Folliculitis decalvans-like pustular plaques on the limbs sparing the scalp. ⁶¹	Yang A...Kossard S	31621894	2020

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Genes for Folliculitis

Genes related to Folliculitis (0 elite genes):

(show all 22)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	14.59	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁴ GeneCards inferred via : Publications (show sections)	11501668
2	IFNG	Interferon Gamma	Protein Coding	12.13	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	IL4	Interleukin 4	Protein Coding	11.76	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	IL5	Interleukin 5	Protein Coding	11.68	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	GNLY	Granulysin	Protein Coding	11.05	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	DEFB4A	Defensin Beta 4A	Protein Coding	10.91	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁴	12534631 15149502
7	PTGDR2	Prostaglandin D2 Receptor 2	Protein Coding	10.88	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	EGF	Epidermal Growth Factor	Protein Coding	10.4	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	10.32	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	FCGR3A	Fc Fragment Of IgG Receptor IIIa	Protein Coding	10.2	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	10.18	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	7.82	DISEASES inferred ¹⁵ ¹⁵
13	LPP	LIM Domain Containing Preferred Translocation Partner In Lipoma	Protein Coding	7.25	DISEASES inferred ¹⁵
14	IL10RB	Interleukin 10 Receptor Subunit Beta	Protein Coding	6.77	DISEASES inferred ¹⁵
15	IL10RA	Interleukin 10 Receptor Subunit Alpha	Protein Coding	6.7	DISEASES inferred ¹⁵
16	CD4	CD4 Molecule	Protein Coding	6.62	DISEASES inferred ¹⁵
17	MBTPS2	Membrane Bound Transcription Factor Peptidase, Site 2	Protein Coding	6.52	DISEASES inferred ¹⁵
18	CD160	CD160 Molecule	Protein Coding	6.32	GeneCards inferred via : Publications (show sections)
19	CD1E	CD1e Molecule	Protein Coding	6.2	DISEASES inferred ¹⁵
20	CD1A	CD1a Molecule	Protein Coding	6.16	DISEASES inferred ¹⁵
21	CD1B	CD1b Molecule	Protein Coding	6.15	DISEASES inferred ¹⁵
22	TNF	Tumor Necrosis Factor	Protein Coding	6.03	DISEASES inferred ¹⁵

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Variations for Folliculitis

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Expression for Folliculitis

Search GEO for disease gene expression data for Folliculitis.

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Pathways for Folliculitis

Pathways related to Folliculitis according to GeneCards Suite gene sharing:

(show all 38)

#	Super pathways	Score	Top Affiliating Genes
1	ERK Signaling ⁶³ Show member pathways ILK Signaling ⁶³ MAPK Signaling ⁶³ Molecular Mechanisms of Cancer ⁶³ Rho Family GTPases ⁶³	13.8	IL5 IL4 IL2RA IL10RB IL10RA EGF
2	Innate Immune System ⁶⁵ Show member pathways Immune System ⁶⁵ Neutrophil degranulation ⁶⁵	13.75	IL5 IL4 IL2RA IL10RB IL10RA IFNG
3	PEDF Induced Signaling ⁶³ Show member pathways all-trans-Retinoic Acid Signaling in Brain ⁶³ Cytokine-cytokine receptor interaction ³⁶ Endothelin-1 Signaling Pathway ⁶³ Glucocorticoid Receptor Signaling ⁶³ IL-6 Pathway ⁶³ MIF Mediated Glucocorticoid Regulation ⁶³ MIF Regulation of Innate Immune Cells ⁶³ NFAT Signaling and Lymphocyte Interactions ⁶³ PGC1Alpha Pathway ⁶³ RAR-Gamma-RXR-Alpha Degradation ⁶³ STAT3 Pathway ⁶³	13.66	IL5 IL4 IL2RA IL10RB IL10RA IFNG
4	TGF-Beta Pathway ⁶³ Show member pathways JAK-STAT Pathway ⁶³ JNK Pathway ⁶³ MAPK Family Pathway ⁶³ Regulation of eIF4 and p70S6K ⁶³ SOCS Pathway ⁶³	13.5	IL5 IL4 IL2RA IL10RB IL10RA IFNG
5	Akt Signaling ⁶³ Show member pathways p38 Signaling ⁶³ Tec Kinases Signaling ⁶³	13.37	IL5 IL4 IL2RA IL10RB IL10RA EGF
6	Cytokine Signaling in Immune system ⁶⁵ Show member pathways Signaling by Interleukins ⁶⁵	13.29	IL5 IL4 IL2RA IL10RB IL10RA IFNG
7	PAK Pathway ⁶³ Show member pathways Antioxidant Action of Vitamin-C ⁶³ Epithelial Adherens Junctions ⁶³	13.17	IL5 IL4 IL2RA IL10RB IL10RA EGF
8	Allograft rejection ¹ ³⁶ Show member pathways Antigen processing and presentation ³⁶ Asthma ³⁶ Autoimmune thyroid disease ³⁶ CTL Mediated Apoptosis ⁶³ Graft-versus-host disease ³⁶ Intestinal immune network for IgA production ³⁶ THC Differentiation Pathway ⁶³ Type I diabetes mellitus ³⁶ Viral myocarditis ³⁶	12.83	IL5 IL4 IL2RA IFNG GNLY CD4
9	Pathways in cancer ³⁶	12.79	IL5 IL4 IL2RA IFNG EGF
10	Immune response NFAT in immune response ²² Show member pathways Immune response CD28 signaling ²² Immune response ICOS pathway in T-helper cell ²² Immune response T cell receptor signaling pathway ²²	12.63	IL4 IL2RA IL10RB IL10RA IFNG CD4
11	T cell receptor signaling pathway ³⁶ Show member pathways PD-L1 expression and PD-1 checkpoint pathway in cancer ³⁶ T-Cell antigen Receptor (TCR) Signaling Pathway ¹ T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection ¹	12.58	IL5 IL4 IFNG EGF CD4
12	Th17 cell differentiation ³⁶ Show member pathways IL-22 Pathway ⁶³ Immune response IL-22 signaling pathway ²² Inflammatory bowel disease (IBD) ³⁶ Th1 and Th2 cell differentiation ³⁶	12.57	IL5 IL4 IL2RA IL10RB IFNG CD4
13	JAK-STAT signaling pathway ³⁶ Show member pathways B-Cell Development ⁶³ IL-7 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁴ Interleukin-19, 20, 22, 24 ⁶⁵ Jak/STAT Signaling Pathway ⁶⁴ Type III interferon signaling ¹	12.37	IL5 IL4 IL2RA IL10RB IL10RA IFNG
14	IL-17 Family Signaling Pathways ⁶⁴ Show member pathways IL17 signaling pathway ¹ IL-17 signaling pathway ³⁶ Interleukin-17 signaling ⁶⁵ Mucin expression in CF via IL-6, IL-17 signaling pathways ²²	12.33	IL5 IL4 IFNG DEFB4A CCL11
15	Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions ⁶⁴ Show member pathways Chemokine receptors bind chemokines ⁶⁵ Viral protein interaction with cytokine and cytokine receptor ³⁶	12.31	IL2RA IL10RB IL10RA CCR6 CCL5 CCL11
16	Defensins ⁶⁵ Show member pathways Alpha-defensins ⁶⁵ Antimicrobial peptides ⁶⁵ Beta defensins ⁶⁵ Ion influx/efflux at host-pathogen interface ⁶⁵ Metal sequestration by antimicrobial proteins ⁶⁵	12.29	GNLY DEFB4A CD4 CCR6
17	Toxoplasmosis ³⁶ Show member pathways Leishmaniasis ³⁶	12.25	IL4 IL10RB IL10RA IFNG FCGR3A
18	Tuberculosis ³⁶	12.2	IL10RB IL10RA IFNG FCGR3A
19	Bacterial infections in CF airways ²² Show member pathways IL-1 beta-dependent CFTR expression ²² Immune response Bacterial infections in normal airways ²² Immune response TLR signaling pathways ²²	12.16	IL4 IFNG DEFB4A CCL11
20	IL12-mediated signaling events ¹ Show member pathways Immune response IL-12-induced IFN-gamma production ²²	11.98	IL4 IL2RA IFNG CD4
21	Hematopoietic Stem Cells and Lineage-specific Markers ⁶⁴	11.86	PTGDR2 IL5 IL4 IL2RA IFNG CD4
22	Th17 Differentiation ⁶⁴ Show member pathways IL-21 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁴	11.81	IL4 IFNG CD4
23	Calcineurin-regulated NFAT-dependent transcription in lymphocytes ¹ Show member pathways Calcium signaling in the CD4+ TCR pathway ¹	11.77	IL5 IL4 IL2RA IFNG
24	Glucocorticoid receptor regulatory network ¹	11.75	IL5 IL4 IFNG
25	Dendritic Cells Developmental Lineage Pathway ⁶⁴	11.7	IFNG CD4 CD1A
26	IL4-mediated signaling events ¹	11.63	IL5 IL4 CCL11
27	Hematopoietic cell lineage ³⁶	11.63	IL5 IL4 IL2RA CD4 CD1E CD1A
28	Lung fibrosis ¹	11.57	IL5 IL4 EGF CCL5 CCL11
29	Interleukin-10 signaling ⁶⁵	11.53	IL4 IL10RB IL10RA CCL5
30	Inflammatory Response Pathway ¹	11.33	IL5 IL4 IL2RA IFNG
31	Development and heterogeneity of the ILC family ¹	11.31	IL5 IL4 IFNG
32	IL12 signaling mediated by STAT4 ¹	11.23	IL2RA IFNG CD4
33	Cytokines and Inflammatory Response ¹	11.22	IL5 IL4 IFNG CD4
34	OX40 Pathway ⁶³	11.2	IL5 IL4 IFNG
35	Innate Lymphoid Cells Differentiation ⁶⁴	11.13	PTGDR2 IL5 IL4 IL2RA IFNG CD4
36	Th2 Differentiation ⁶⁴	11.1	IL5 IL4 IL2RA IFNG CD4 CCL11
37	G-protein signaling_Rap2B regulation pathway ²²	10.98	IL5 IL4 EGF CCL5 CCL11
38	IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁴	10.74	IL5 IL4

Sources

GO Terms for Folliculitis

Cellular components related to Folliculitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.85	IL5 IL4 IFNG GNLY FCGR3A EGF
2	external side of plasma membrane	GO:0009897	9.43	IL2RA FCGR3A CD4 CD1E CD1A CCR6
3	extracellular space	GO:0005615	9.32	IL5 IL4 IFNG GNLY EGF DEFB4A

Biological processes related to Folliculitis according to GeneCards Suite gene sharing:

(show all 23)

#	Name	GO ID	Score	Top Affiliating Genes
1	signal transduction	GO:0007165	10.11	PTGDR2 IL5 IL4 IL10RB EGF CD4
2	MAPK cascade	GO:0000165	9.91	IL5 IL2RA EGF CCL5
3	adaptive immune response	GO:0002250	9.91	IFNG CD4 CD1E CD1A CD160
4	inflammatory response	GO:0006954	9.88	IL5 IL2RA IL10RB CCL5 CCL11
5	positive regulation of cell migration	GO:0030335	9.87	IL4 EGF CCL5 CCL11
6	regulation of immune response	GO:0050776	9.85	IL4 FCGR3A CD1A CD160
7	positive regulation of peptidyl-tyrosine phosphorylation	GO:0050731	9.79	IL5 EGF CD4
8	cell chemotaxis	GO:0060326	9.77	DEFB4A CCR6 CCL5
9	defense response to Gram-negative bacterium	GO:0050829	9.76	DEFB4A CD4 CD160
10	chemokine-mediated signaling pathway	GO:0070098	9.71	CCR6 CCL5 CCL11
11	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	9.7	IL4 IFNG CCL5
12	chemotaxis	GO:0006935	9.65	PTGDR2 DEFB4A CCR6 CCL5 CCL11
13	positive regulation of T cell proliferation	GO:0042102	9.62	IL4 IL2RA CD4 CCL5
14	positive regulation of chemokine biosynthetic process	GO:0045080	9.6	IL4 IFNG
15	regulation of T cell activation	GO:0050863	9.58	CD4 CCL5
16	positive regulation of MHC class II biosynthetic process	GO:0045348	9.56	IL4 IFNG
17	cytokine-mediated signaling pathway	GO:0019221	9.56	IL5 IL4 IL2RA IL10RB IL10RA CD4
18	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	GO:0048007	9.49	CD1E CD1A
19	immune response	GO:0006955	9.47	PTGDR2 IL5 IL4 IL2RA IL10RB IFNG
20	positive regulation of JAK-STAT cascade	GO:0046427	9.46	IL5 IL10RB IL10RA CCL5
21	positive regulation of cellular respiration	GO:1901857	9.43	IL4 IFNG
22	neuroinflammatory response	GO:0150076	9.4	IL4 IFNG
23	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	GO:0048006	9.37	CD1E CD1A

Molecular functions related to Folliculitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	signaling receptor activity	GO:0038023	9.67	IL10RB IL10RA CD4 CCR6
2	lipopeptide binding	GO:0071723	9.32	CD1E CD1A
3	exogenous lipid antigen binding	GO:0030884	9.26	CD1E CD1A
4	endogenous lipid antigen binding	GO:0030883	9.16	CD1E CD1A
5	cytokine activity	GO:0005125	9.02	IL5 IL4 IFNG CCL5 CCL11
6	interleukin-10 receptor activity	GO:0004920	8.96	IL10RB IL10RA

Sources

Sources for Folliculitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

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²³ GeneHancer via GeneCards

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³⁵ IUPHAR

³⁶ KEGG

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⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

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⁵¹ NIH Clinical Center

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⁵³ NINDS

⁵⁴ Novoseek

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⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

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⁶¹ PubMed

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⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia