Folliculitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: FLL008 MIFTS: 46	Folliculitis Categories: Skin diseases	Data Licensing For inquiries, contact: [email protected]
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Folliculitis

MalaCards integrated aliases for Folliculitis:

Name: Folliculitis ¹¹ ⁵³ ⁴³ ¹⁴ ¹⁶ ⁷¹ ⁷⁵

Classifications:

MalaCards categories:
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:4409

MeSH ⁴³ D005499

NCIt ⁴⁹ C94408

SNOMED-CT ⁶⁸ 156411003

EFO ¹⁶ EFO_1000702

UMLS ⁷¹ C0016436

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Summaries for Folliculitis

MalaCards based summary: Folliculitis is related to hypereosinophilic syndrome and herpes zoster, and has symptoms including exanthema An important gene associated with Folliculitis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are ERK Signaling and MIF Mediated Glucocorticoid Regulation. The drugs Ketoconazole and Retapamulin have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and bone marrow, and related phenotypes are homeostasis/metabolism and immune system

Wikipedia: ⁷⁵ Folliculitis is the infection and inflammation of one or more hair follicles. The condition may occur... more...

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Related Diseases for Folliculitis

Diseases related to Folliculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 742)

#	Related Disease	Score	Top Affiliating Genes
1	hypereosinophilic syndrome	30.9	IL5 IL4 IFNG CCL5 CCL11
2	herpes zoster	30.7	IFNG FCGR3A CD4 CCR6
3	exanthem	30.6	TNF IL4 IFNG CD4 CCR6
4	follicular mucinosis	30.5	CD4 CD1E
5	dermatitis	30.5	TNF IL5 IL4 IFNG CCR6 CCL11
6	dermatophytosis	30.4	TNF DEFB4A CD4 CCR6
7	acquired immunodeficiency syndrome	30.4	TNF IFNG FCGR3A CD4
8	ige responsiveness, atopic	30.4	IL5 IL4 IFNG
9	mycosis fungoides	30.4	IL5 IL4 IFNG CCR6
10	human immunodeficiency virus type 1	30.3	IFNG CD4 CCL5 CCL11
11	histiocytosis	30.2	TNF IL4 IFNG CCR6
12	smallpox	30.2	TNF IL4 IFNG
13	cellulitis	30.1	TNF IL5 DEFB4A CD4 CCR6
14	thyroiditis	30.1	TNF IL4 IFNG
15	kimura disease	30.1	IL5 IL4 CD1E
16	lymphadenitis	30.1	TNF IFNG CCR6
17	chronic rhinitis	30.0	PTGDR2 IL5 IL4
18	lichen planus	30.0	TNF IL4 IFNG DEFB4A
19	langerhans cell histiocytosis	30.0	TNF CD1E CCR6
20	chickenpox	30.0	TNF IL4 IFNG FCGR3A CD4 CCR6
21	syphilis	29.9	TNF CD4 CCR6
22	alopecia areata	29.9	TNF IL4 IFNG
23	primary cutaneous t-cell non-hodgkin lymphoma	29.9	IL5 IL4 IFNG CD4 CCR6
24	pulmonary eosinophilia	29.9	IL5 IL4 CCL5 CCL11
25	scabies	29.9	IL5 IL4 CD4 CD1E CCR6
26	drug allergy	29.9	IL5 IL4 CD4
27	eczema herpeticum	29.9	IL4 DEFB4A CCR6
28	seborrheic dermatitis	29.8	TNF DEFB4A CD4 CD1E CCR6
29	immune deficiency disease	29.8	TNF IL4 IFNG FCGR3A CD4 CCR6
30	anogenital venereal wart	29.8	TNF CD4 CCR6
31	tropical spastic paraparesis	29.8	IFNG CD4 CCL5
32	corneal ulcer	29.8	TNF EGF CCL11
33	erythema multiforme	29.8	TNF IL5 IL4 IFNG GNLY CCL5
34	viral infectious disease	29.8	TNF IL4 IFNG CD4 CCR6 CCL5
35	pericarditis	29.8	TRAF3IP2 TNF IFNG
36	sclerosing cholangitis	29.8	TNF CD4 CCR6
37	candidiasis	29.8	TRAF3IP2 TNF IL5 IL4 IL17RA IFNG
38	leishmaniasis	29.8	TNF IL5 IL4 IFNG
39	sezary's disease	29.8	IL5 IL4 IFNG CD4 CCR6
40	hyper ige recurrent infection syndrome 1	29.8	IL17RA CD4 CCR6
41	panniculitis	29.8	IFNG CD4 CCR6
42	allergic rhinitis	29.8	IL5 IL4 IFNG CCL5 CCL11
43	blepharitis	29.7	TNF IL4 CD4 CCR6
44	granuloma annulare	29.7	TNF CD4 CD1E
45	sporotrichosis	29.7	TNF IFNG CD4
46	cystitis	29.7	TNF IL4 EGF
47	macs syndrome	29.7	TNF IFNG CD4
48	osteomyelitis	29.7	TNF IL4 IFNG CCL5
49	alcohol use disorder	29.7	TNF CD4 CCR6
50	localized scleroderma	29.7	TNF IL4 CD4

Graphical network of the top 20 diseases related to Folliculitis:

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Symptoms & Phenotypes for Folliculitis

UMLS symptoms related to Folliculitis:

exanthema

GenomeRNAi Phenotypes related to Folliculitis according to GeneCards Suite gene sharing:

²⁵

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	no effect	GR00402-S-1	10.18	CCL11 CCL5 CCR6 CD160 CD1E CD4
2	no effect	GR00402-S-2	10.18	CCL11 CCL5 CCR6 CD160 CD1E CD4

MGI Mouse Phenotypes related to Folliculitis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	10.17	CCR6 CD160 CD4 FCGR3A IFNG IL10RA
2	immune system	MP:0005387	10.11	CCL11 CCL5 CCR6 CD160 CD4 DEFB4A
3	digestive/alimentary	MP:0005381	9.96	CD4 EGF IFNG IL10RA IL10RB IL4
4	respiratory system	MP:0005388	9.56	CCL11 IFNG IL10RB IL17RA IL4 IL5
5	hematopoietic system	MP:0005397	9.55	CCL11 CCL5 CCR6 CD160 CD4 DEFB4A

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Drugs & Therapeutics for Folliculitis

Drugs for Folliculitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Ketoconazole

Approved, Investigational

Phase 4

65277-42-1, 142128-57-2

47576 3823 638701

Retapamulin

Approved

Phase 4

224452-66-8

6918462

Cephalexin

Approved, Investigational, Vet_approved

Phase 4

15686-71-2

27447

Meticillin

Approved, Investigational

Phase 4

61-32-5

6087

Clindamycin

Approved, Vet_approved

Phase 4

18323-44-9, 24729-96-2

29029

Clindamycin phosphate

Phase 4

32603

Clindamycin palmitate

Phase 4

Miconazole

Approved, Investigational, Vet_approved

Phase 2, Phase 3

22916-47-8

4189

Clotrimazole

Approved, Vet_approved

Phase 2, Phase 3

23593-75-1

2812

Hormones

Phase 2, Phase 3

Hormone Antagonists

Phase 2, Phase 3

glucocorticoids

Phase 2, Phase 3

Anti-Inflammatory Agents

Phase 2, Phase 3

Anti-Infective Agents

Phase 2, Phase 3

Antifungal Agents

Phase 2, Phase 3

Cytochrome P-450 Enzyme Inhibitors

Phase 2, Phase 3

Cytochrome P-450 CYP3A Inhibitors

Phase 2, Phase 3

Anti-Bacterial Agents

Phase 2, Phase 3

Anti-Asthmatic Agents

Phase 2, Phase 3

Respiratory System Agents

Phase 2, Phase 3

Beclomethasone

Phase 2, Phase 3

2308 20469

Anti-Infective Agents, Local

Phase 2, Phase 3

Gentamicins

Phase 2, Phase 3

Dermatologic Agents

Phase 2, Phase 3

Cetuximab

Approved

Phase 2

205923-56-4

Phylloquinone

Approved, Investigational

Phase 2

84-80-0

5284607

Betamethasone

Approved, Vet_approved

Phase 2

378-44-9

9782

Erlotinib

Approved, Investigational

Phase 2

183319-69-9, 183321-74-6

176870

Menadione

Approved, Nutraceutical

Phase 2

58-27-5

4055

Menaquinone

Investigational

Phase 2

1182-68-9

Vitamins

Phase 2

Vitamin K 3

Phase 2

Vitamin K

Phase 2

Trace Elements

Phase 2

Antifibrinolytic Agents

Phase 2

Hemostatics

Phase 2

Naphthoquinone

Phase 2

Micronutrients

Phase 2

Coagulants

Phase 2

Betamethasone-17,21-dipropionate

Phase 2

Betamethasone Valerate

Phase 2

2152-44-5

Betamethasone sodium phosphate

Phase 2

Betamethasone benzoate

Phase 2

Mitogens

Phase 2

Triamcinolone

Approved, Vet_approved

124-94-7

31307

Mupirocin

Approved, Investigational, Vet_approved

12650-69-0

446596

Itraconazole

Approved, Investigational

84625-61-6

55283

Triamcinolone hexacetonide

Triamcinolone diacetate

Triamcinolone Acetonide

6436

Interventional clinical trials:

(show all 13)

#	Name	Status	NCT ID	Phase	Drugs
1	An Open-Label, Proof of Concept Study to Determine the Safety and Efficacy of Ketoconazole 2% Foam in the Treatment of Pityrosporum Folliculitis	Completed	NCT00824863	Phase 4	ketoconazole 2% foam
2	Randomized Clinical Trial of Wound Packing Following Incision and Drainage of Superficial Skin Abscesses in the Pediatric Emergency Department	Completed	NCT00746109	Phase 4
3	Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection	Completed	NCT01126268	Phase 4	Retapamulin (Altabax)
4	Comparison of Cephalexin Versus Clindamycin in the Empiric, Outpatient Treatment of Suspected Staphylococcal Cutaneous Infections in the Era of Community-associated Methicillin-resistant Staphylococcus Aureus (CA-MRSA)	Completed	NCT00352612	Phase 4	clindamycin;cephalexin
5	Isolation and Comparative Efficacy of the Combination of beclometasona0, 025% + Gentamicin 0.1% + Clotrimazole 1% Topical Dermatological Cream of GLENMARK PHARMACEUTICALS, in Patients Infected With Acne	Suspended	NCT01244256	Phase 2, Phase 3	Clotrimazole + Gentamicin + Beclomethasone;Clotrimazole + Gentamicin
6	Placebo-controlled Trial Investigating the Effect of Vitamin K3-lotion for the Treatment of Cetuximab Induced Folliculitis	Completed	NCT01094444	Phase 2
7	Phase II Multicentric Study About Preventive Treatment of Folliculitis Induced by the EGF-R Inhibitors in Patients With Metastatic Colorectal Cancer and Treated by Cetuximab or With Non-small-cell Lung Carcinoma Treated by Erlotinib	Completed	NCT00910676	Phase 2	Diprosone
8	Prospective, Controlled Study of the Efficacy of NdYag for Acne Keloidalis Nuchae	Unknown status	NCT00757315		Topical corticosteroid alone
9	Role of Staphylococcus Aureus on Folliculitis Decalvans. A Comparative Bacteriological Study.	Completed	NCT02157688
10	Post Market Study Using The Elite IQ Device	Completed	NCT04807205
11	An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus Infection in Soldiers: a Controlled Trial	Completed	NCT00289588		Mupirocin (drug)
12	Effect of Cold Atmospheric Plasma on Malassezia Folliculitis: a Randomized Controlled Trial	Recruiting	NCT04886323		Itraconazole Capsules
13	Open, Non-comparative, Multicentre, Interventional Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Ialuxid Gel in the Treatment of Acne Vulgaris, Impetigo and Folliculitis	Not yet recruiting	NCT05345093

Search NIH Clinical Center for Folliculitis

Cochrane evidence based reviews: folliculitis

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Genetic Tests for Folliculitis

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Anatomical Context for Folliculitis

Organs/tissues related to Folliculitis:

MalaCards : Skin, Lung, Bone Marrow, Bone, Thyroid, Breast, Neutrophil

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Publications for Folliculitis

Articles related to Folliculitis:

(show top 50) (show all 2537)

#	Title	Authors	PMID	Year
1	Involvement of granulysin-producing T cells in the development of superficial microbial folliculitis. ⁵³ ⁶²	Oono T...Iwatsuki K	15149502	2004
2	Localization of human beta-defensin-2 and human neutrophil peptides in superficial folliculitis. ⁵³ ⁶²	Oono T...Iwatsuki K	12534631	2003
3	Role of Th2 cytokines, RANTES and eotaxin in AIDS-associated eosinophilic folliculitis. ⁵³ ⁶²	Amerio P...Sauder DN	11501668	2001
4	Folliculitis decalvans and dystrophic epidermolysis bullosa: a significant association. ⁶²	Matard B...Reygagne P	35904062	2022
5	Production and Quantification of Virulence Factors in Malassezia Species. ⁶²	Hadrich I...Ayadi A	36473111	2022
6	Possible interaction between eosinophils and other immune cells in the pathomechanism of eosinophilic pustular folliculitis. ⁶²	Ichimura R...Ohtsuki M	35398896	2022
7	Intervention efficacy of MARSI nursing management on skin injury at peripherally inserted central catheter insertion site on oncological patients. ⁶²	Zhao Y...Yang J	35570386	2022
8	Breast Autologous Fat Transfer Entirely Under Tumescent Anesthesia: Safety and Efficacy. ⁶²	Salmon PJM	36449875	2022
9	Efficacy and safety of oral pioglitazone in the management of lichen planopilaris in comparison with clobetasol: A randomized clinical trial. ⁶²	Lajevardi V...Peymanfar AA	36169160	2022
10	Eosinophilic pustule smear in the diagnosis of pediatric post-transplant eosinophilic folliculitis. ⁶²	Pupa L...Hunt R	36379224	2022
11	Management of folliculitis decalvans with ayurveda- A case report. ⁶²	Gautam S...Joshi RK	36436296	2022
12	Perforating folliculitis. ⁶²	Diez-Madueno K...de la Cueva Dobao P	35945061	2022
13	[Translated article] Chronic Lichenoid Folliculitis Decalvans. ⁶²	Lopez Mateos A...Azana Defez JM	36206816	2022
14	Chronic Lichenoid Folliculitis Decalvans. ⁶²	Lopez Mateos A...Azana Defez JM	35469792	2022
15	Eosinophilic pustular folliculitis developing at the site of COVID-19 vaccination. ⁶²	Rikitake S...Fujimoto N	35699624	2022
16	Drug Survival of Oral Retinoids in Hidradenitis Suppurativa: A Real-Life Cohort Study. ⁶²	Bouwman K...Horvath B	36070059	2022
17	KERATIN 17-related recessive atypical pachyonychia congenita with variable hair and tooth anomalies. ⁶²	Koprulu M...Tolun A	35676340	2022
18	Eosinophilic pustular folliculitis due to naltrexone: A case report. ⁶²	Smith SS...Tonti E	35987727	2022
19	Clearance of atypical cutaneous manifestations of hyper-IgE syndrome with dupilumab. ⁶²	Nihal A...Arkin LM	35734823	2022
20	Acneiform Eruption Following Elexacaftor-Tezacaftor-Ivacaftor Treatment in Patients With Cystic Fibrosis. ⁶²	Okroglic L...Oules B	36449298	2022
21	A first-in-human, phase 1a dose-escalation study of the selective MEK1/2 inhibitor FCN-159 in patients with advanced NRAS-mutant melanoma. ⁶²	Mao L...Si L	36113242	2022
22	Syphilitic Folliculitis: A Case Report With Demonstration of Spirochetes Showing Follicular Epitheliotropism. ⁶²	Isler MF...Ruhoy SM	35925589	2022
23	Optimizing Antibiotic Treatment of Skin Infections in Pediatric Emergency and Urgent Care Centers. ⁶²	Wiltrakis SM...Jain S	36073197	2022
24	Facial demodicosis in the immunosuppressed state: a retrospective case series from a tertiary referral center. ⁶²	Amitay-Laish I...Segal R	35398883	2022
25	One-year safety and efficacy of tapinarof cream for the treatment of plaque psoriasis: Results from the PSOARING 3 trial. ⁶²	Strober B...Lebwohl MG	35772599	2022
26	Tapinarof for the treatment of psoriasis. ⁶²	Nogueira S...Torres T	36226669	2022
27	Clinico-laboratory findings of Malassezia folliculitis in Indonesia: A multicentre study. ⁶²	Niode NJ...Widaty S	35920036	2022
28	Necrotizing Infundibular Crystalline Folliculitis-A Case Report of a Rare Entity and Review of the Literature. ⁶²	Wiedemeyer K...Naert K	36122337	2022
29	Refractory folliculitis decalvans treated with biologics: Case series in 4 situations. ⁶²	Lobato-Berezo A...Pujol RM	35988046	2022
30	Therapeutic options for perifolliculitis capitis abscedens et suffodens: A review. ⁶²	Wu Q...Fang F	35946169	2022
31	Factors affecting the outcome of fractional carbon dioxide laser resurfacing of various types of scars in skin of color. ⁶²	Maninder K...Suman P	34932873	2022
32	Tufted hairs: A bouquet of flowers in different hair diseases. ⁶²	Starace M...Piraccini BM	35001495	2022
33	Refractory folliculitis decalvans treated with adalimumab: A case series of 23 patients. ⁶²	Iorizzo M...Tosti A	35245565	2022
34	Demodex: The worst enemies are the ones that used to be friends. ⁶²	Paichitrojjana A	36199896	2022
35	Does SAPHO syndrome exist in dermatology? ⁶²	Chen W...Plewig G	35462435	2022
36	Changing spectrum of hair and scalp disorders over the last decade in a tertiary medical centre. ⁶²	Lyakhovitsky A...Barzilai A	36066315	2022
37	Orbital myositis as an initial manifestation of Behcet's disease. ⁶²	Abe S...Hayashi A	35845748	2022
38	Malassezia Folliculitis following Triple Therapy for Cystic Fibrosis. ⁶²	Li Pomi F...Borgia F	36143881	2022
39	Dupilumab-induced skin-associated side effects in patients with chronic rhinosinusitis with nasal polyposis. ⁶²	Chromy D...Bangert C	36177732	2022
40	Facial dermatitis in a healthy 9-year-old boy. ⁶²	Hiep A...Gross E	36007117	2022
41	Marginal Traction Alopecia: Hair Care Practices, Severity Score and Trichoscopic Features in Lagos, Nigeria. ⁶²	Anaba EL...Akwara I	36057972	2022
42	Pelodera strongyloides in the critically endangered Apennine brown bear (Ursus arctos marsicanus). ⁶²	Di Bari MA...Agrimi U	35168109	2022
43	Difficulties in diagnosing Malassezia furfur bloodstream infection and possibility of spontaneous resolution in a patient undergoing chemotherapy for neuroblastoma: A case report. ⁶²	Tetsuka N...Yagi T	35279379	2022
44	Effectiveness of FastFung agar in the isolation of Malassezia furfur from skin samples. ⁶²	Atsu N...Ilkit M	35506984	2022
45	Skin and respiratory ill-health attributed to occupational face mask use. ⁶²	Seed MJ...van Tongeren M	35689550	2022
46	Inflammatory complications after hair transplantation: Report of 10 cases. ⁶²	Saad S...Reygagne P	35841210	2022
47	Cutaneous manifestations of obesity in Turkish children: A comparative study. ⁶²	Guven M...Sendur N	35285075	2022
48	Dermatitis Cruris Pustulosa et Atrophicans: Scarring Alopecia Beyond Scalp Hair. ⁶²	Joao AL...Lencastre A	35983463	2022
49	Folliculitis caused by Pantoea dispersa as a souvenir from a self-discovery excursion in bat caves. ⁶²	Preis S...Zink A	35677602	2022
50	Pityrosporum folliculitis in immunocompromised populations: A systematic review. ⁶²	Green M...Maibach H	35868569	2022

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Genes for Folliculitis

Genes related to Folliculitis (0 elite genes):

(show all 24)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	15.04	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11501668
2	IFNG	Interferon Gamma	Protein Coding	13.03	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
3	IL4	Interleukin 4	Protein Coding	12.88	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
4	IL5	Interleukin 5	Protein Coding	12.55	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
5	IL17RA	Interleukin 17 Receptor A	Protein Coding	12.3	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
6	PTGDR2	Prostaglandin D2 Receptor 2	Protein Coding	11.96	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
7	TRAF3IP2	TRAF3 Interacting Protein 2	Protein Coding	11.66	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
8	GNLY	Granulysin	Protein Coding	11.55	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
9	EGF	Epidermal Growth Factor	Protein Coding	11.24	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
10	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	11.23	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
11	FCGR3A	Fc Gamma Receptor IIIa	Protein Coding	11	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
12	DEFB4A	Defensin Beta 4A	Protein Coding	10.73	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	12534631 15149502
13	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	10.67	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
14	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	8.37	DISEASES inferred ¹⁴ ¹⁴
15	CD160	CD160 Molecule	Protein Coding	7.31	GeneCards inferred via : Publications (show sections)
16	IL10RB	Interleukin 10 Receptor Subunit Beta	Protein Coding	6.6	DISEASES inferred ¹⁴
17	IL10RA	Interleukin 10 Receptor Subunit Alpha	Protein Coding	6.54	DISEASES inferred ¹⁴
18	CD4	CD4 Molecule	Protein Coding	6.44	DISEASES inferred ¹⁴
19	TNF	Tumor Necrosis Factor	Protein Coding	6.1	DISEASES inferred ¹⁴
20	CD1E	CD1e Molecule	Protein Coding	5.93	DISEASES inferred ¹⁴
21	CD1A	CD1a Molecule	Protein Coding	5.9	DISEASES inferred ¹⁴
22	IL10	Interleukin 10	Protein Coding	5.88	DISEASES inferred ¹⁴
23	CD1B	CD1b Molecule	Protein Coding	5.88	DISEASES inferred ¹⁴
24	IL17A	Interleukin 17A	Protein Coding	5.87	DISEASES inferred ¹⁴

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Variations for Folliculitis

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Expression for Folliculitis

Search GEO for disease gene expression data for Folliculitis.

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Pathways for Folliculitis

Pathways related to Folliculitis according to GeneCards Suite gene sharing:

(show top 50) (show all 51)

#	Super pathways	Score	Top Affiliating Genes
1	ERK Signaling ⁶⁴ Show member pathways ILK Signaling ⁶⁴ MAPK Signaling ⁶⁴ Molecular Mechanisms of Cancer ⁶⁴ Rho Family GTPases ⁶⁴	13.79	TRAF6 TNF IL5 IL4 IL17RA IL10RB
2	MIF Mediated Glucocorticoid Regulation ⁶⁴ Show member pathways all-trans-Retinoic Acid Signaling in Brain ⁶⁴ Endothelin-1 Signaling Pathway ⁶⁴ Glucocorticoid Receptor Signaling ⁶⁴ IL-6 Pathway ⁶⁴ MIF Regulation of Innate Immune Cells ⁶⁴ NFAT Signaling and Lymphocyte Interactions ⁶⁴ Overview of proinflammatory and profibrotic mediators ⁷⁴ PEDF Induced Signaling ⁶⁴ PGC1Alpha Pathway ⁶⁴ RAR-Gamma-RXR-Alpha Degradation ⁶⁴ STAT3 Pathway ⁶⁴	13.61	TNF IL5 IL4 IL17RA IL10RB IL10RA
3	Innate Immune System ⁶⁶ Show member pathways Immune System ⁶⁶ Neutrophil degranulation ⁶⁶	13.61	TRAF6 TNF IL5 IL4 IL17RA IL10RB
4	TGF-Beta Pathway ⁶⁴ Show member pathways JAK-STAT Pathway ⁶⁴ JNK Pathway ⁶⁴ MAPK Family Pathway ⁶⁴ Regulation of eIF4 and p70S6K ⁶⁴ SOCS Pathway ⁶⁴	13.54	TNF IL5 IL4 IL10RB IL10RA IFNG
5	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.22	CCL11 CCL5 CD4 IFNG IL10RA IL10RB
6	Akt Signaling ⁶⁴ Show member pathways p38 Signaling ⁶⁴ Tec Kinases Signaling ⁶⁴	13.18	CCL11 CCL5 CCR6 CD4 EGF IL10RA
7	PAK Pathway ⁶⁴ Show member pathways Antioxidant Action of Vitamin-C ⁶⁴ Epithelial Adherens Junctions ⁶⁴	13.17	TNF IL5 IL4 IL17RA IL10RB IL10RA
8	4-1BB Pathway ⁶⁴ Show member pathways CD27 Pathway ⁶⁴ CD40 Signaling ⁶⁴ CMV and MAPK Pathways ⁶⁴ NF-KappaB Activation by EBV ⁶⁴ NF-kappaB Activation by Viruses ⁶⁴ PKR Pathway ⁶⁴ SUMO Pathway ⁶⁴ TNFR2 Pathway ⁶⁴	12.7	TRAF6 TRAF3IP2 TNF IFNG EGF CD4
9	Overview of interferons-mediated signaling pathway ⁷⁴ Show member pathways all-trans-Retinoic Acid Mediated Apoptosis ⁶⁴ Cytokine Network ⁶⁴ Immune response IFN alpha/beta signaling pathway ²² Interferon alpha/beta signaling ⁶⁶ Jak/STAT Signaling Pathway ⁶⁵ Regulation of IFNA/IFNB signaling ⁶⁶ Type III interferon signaling ⁷⁴	12.67	EGF IFNG IL10RA IL10RB IL4 IL5
10	Immune response IL-23 signaling pathway ²² Show member pathways Angiopoietin receptor Tie2-mediated signaling ⁶¹ Angiopoietin-TIE2 Signaling ⁶⁴ Development Angiopoietin - Tie2 signaling ²² Development PDGF signaling via STATs and NF-kB ²² IL23-mediated signaling events ⁶¹ Immune response IL-10 signaling pathway ²² RAC1/PAK1/p38/MMP2 pathway ⁷⁴	12.6	TNF IL10RB IL10RA IFNG CD4
11	NF-kappaB Signaling ³	12.59	TRAF6 TNF IL4 IFNG CCL5
12	Bacterial infections in CF airways ²² Show member pathways Altered glycosylation of MUC1 in tumor microenvironment ⁷⁴ IL-1 beta-dependent CFTR expression ²² IL1-mediated signaling events ⁶¹ Immune response Bacterial infections in normal airways ²² Immune response TLR signaling pathways ²² NTHi-Induced Signaling ⁶⁴ Signal transduction through IL1R ⁷⁴	12.43	TRAF6 TNF IL4 IFNG DEFB4A CCL11
13	Defensins ⁶⁶ Show member pathways Alpha-defensins ⁶⁶ Antimicrobial peptides ⁶⁶ Beta defensins ⁶⁶ Ion influx/efflux at host-pathogen interface ⁶⁶ Metal sequestration by antimicrobial proteins ⁶⁶	12.31	GNLY DEFB4A CD4 CCR6
14	IL-17 Family Signaling Pathways ⁶⁵ Show member pathways IL17 signaling pathway ⁶⁷ IL-17 signaling pathway ⁷⁴ Mucin expression in CF via IL-6, IL-17 signaling pathways ²²	12.28	TRAF6 TRAF3IP2 TNF IL17RA
15	Immune response CD16 signaling in NK cells ²² Show member pathways Immune response Role of DAP12 receptors in NK cells ²²	12.21	TNF IL4 IFNG FCGR3A
16	T-cell activation SARS-CoV-2 ⁷⁴ Show member pathways T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection ⁷⁴	12.18	TNF IL5 IL4 IFNG CD4
17	Neuroinflammation and glutamatergic signaling ⁷⁴	12.13	TNF IL4 IL10RB IL10RA IFNG
18	IL12-mediated signaling events ⁶¹ Show member pathways Immune response IL-12-induced IFN-gamma production ²²	12	TRAF6 IL4 IFNG CD4
19	Hematopoietic Stem Cells and Lineage-specific Markers ⁶⁵	11.97	TNF PTGDR2 IL5 IL4 IFNG CD4
20	Th17 Differentiation ⁶⁵ Show member pathways IL-21 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁵	11.91	IL4 IL17RA IFNG CD4
21	Allograft rejection ⁷⁴	11.89	GNLY IFNG IL4 IL5 TNF
22	Cytokine production by Th17 cells in CF (Mouse model) ²² Show member pathways Cytokine production by Th17 cells in CF ²²	11.85	TRAF6 TRAF3IP2 IL17RA
23	Dendritic Cells Developmental Lineage Pathway ⁶⁵	11.81	TNF IL17RA IFNG CD4
24	Glucocorticoid receptor regulatory network ⁶¹	11.77	IL5 IL4 IFNG
25	Calcineurin-regulated NFAT-dependent transcription in lymphocytes ⁶¹ Show member pathways Calcium signaling in the CD4+ TCR pathway ⁶¹	11.76	TNF IL5 IL4 IFNG
26	Extrafollicular B cell activation by SARS-CoV-2 ⁷⁴	11.73	TNF IL4 IFNG
27	Th17 cell differentiation pathway ⁷⁴	11.72	IL4 IFNG CD4
28	IL 10 signaling pathway ⁶⁷	11.72	TRAF6 TNF IL10RB IL10RA
29	AP-1 transcription factor network ⁶¹	11.71	IL5 IL4 IFNG
30	Inflammatory bowel disease signaling ⁷⁴ Show member pathways Ulcerative colitis signaling ⁷⁴	11.68	TNF IL5 IL4 IFNG
31	Photodynamic therapy-induced NF-kB survival signaling ⁷⁴ Show member pathways Immune response MIF-mediated glucocorticoid regulation ²²	11.67	TRAF6 TNF IFNG
32	IL4-mediated signaling events ⁶¹	11.64	IL5 IL4 CCL11
33	SARS-CoV-2 innate immunity evasion and cell-specific immune response ⁷⁴	11.6	TRAF6 TNF CD160 CCL5
34	Non-genomic actions of 1,25 dihydroxyvitamin D3 ⁷⁴	11.57	TNF IFNG DEFB4A
35	THC Differentiation Pathway ⁶⁴	11.56	TNF IL4 IL10RB IL10RA IFNG CD4
36	Interleukin-10 signaling ⁶⁶	11.55	CCL5 IL10RA IL10RB TNF
37	Interactions between immune cells and microRNAs in tumor microenvironment ⁷⁴	11.54	CCL5 IL4 TRAF6
38	Th2 Differentiation ⁶⁵	11.52	IL5 IL4 IFNG CD4 CCL11
39	IL-10 Pathway ⁶⁴	11.39	TNF IL10RB IL10RA
40	Inflammatory response pathway ⁷⁴	11.36	IL5 IL4 IFNG
41	Development and heterogeneity of the ILC family ⁷⁴	11.35	TNF IL5 IL4 IFNG
42	OX40 Pathway ⁶⁴	11.25	IFNG IL4 IL5
43	Interactions of natural killer cells in pancreatic cancer ⁷⁴	11.24	TNF IFNG FCGR3A CCL5
44	Immune infiltration in pancreatic cancer ⁷⁴	11.23	TNF IL5 IL4 IFNG
45	Lung fibrosis ⁷⁴	11.23	TNF IL5 IL4 EGF CCL5 CCL11
46	Ebstein-Barr virus LMP1 signaling ⁷⁴	11.19	TRAF6 TNF CCL5
47	Cytokines and inflammatory response ⁷⁴	11.18	TNF IL5 IL4 IFNG CD4
48	Innate Lymphoid Cells Differentiation ⁶⁵	11.13	TNF PTGDR2 IL5 IL4 IFNG CD4
49	G-protein signaling_Rap2B regulation pathway ²²	11.04	TNF IL5 IL4 EGF CCL5 CCL11
50	Selective expression of chemokine receptors during T-cell polarization ⁷⁴	10.99	IL4 IFNG CD4

Sources

GO Terms for Folliculitis

Cellular components related to Folliculitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	10.2	TNF IL5 IL4 IFNG GNLY FCGR3A
2	extracellular region	GO:0005576	10.02	CCL11 CCL5 CD160 DEFB4A EGF FCGR3A
3	plasma membrane	GO:0005886	9.74	TNF PTGDR2 IL17RA IL10RB IL10RA FCGR3A
4	plasma membrane	GO:0005887	9.74	TNF PTGDR2 IL17RA IL10RB IL10RA FCGR3A

Biological processes related to Folliculitis according to GeneCards Suite gene sharing:

(show all 23)

#	Name	GO ID	Score	Top Affiliating Genes
1	signal transduction	GO:0007165	10.37	CCL11 CCL5 CCR6 CD4 IFNG IL10RB
2	inflammatory response	GO:0006954	10.25	CCL11 CCL5 IL10RB IL17RA IL5 TNF
3	positive regulation of interleukin-6 production	GO:0032755	10.17	TRAF6 TNF IL17RA IFNG
4	chemotaxis	GO:0006935	10.13	PTGDR2 DEFB4A CCR6 CCL5 CCL11
5	regulation of insulin secretion	GO:0050796	10.08	TNF IFNG CCL5
6	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	10.08	TNF IL4 IFNG CCL5
7	response to virus	GO:0009615	10.07	TNF IL17RA IFNG CCL5 CCL11
8	immune system process	GO:0002376	10.06	CD160 CD1E CD4 FCGR3A IL17RA TRAF6
9	humoral immune response	GO:0006959	10.06	CCR6 IFNG TNF TRAF3IP2
10	defense response to fungus	GO:0050832	10.05	IL17RA GNLY DEFB4A
11	microglial cell activation	GO:0001774	10.01	TNF IL4 IFNG
12	positive regulation of osteoclast differentiation	GO:0045672	10	TRAF6 TNF IFNG
13	neuroinflammatory response	GO:0150076	9.91	IL4 IFNG
14	positive regulation of mononuclear cell migration	GO:0071677	9.9	TNF IL4
15	T-helper 17 type immune response	GO:0072538	9.89	TRAF3IP2 IL17RA
16	positive regulation of nitrogen compound metabolic process	GO:0051173	9.86	IFNG TNF
17	positive regulation of calcidiol 1-monooxygenase activity	GO:0060559	9.85	IFNG TNF
18	calcium-mediated signaling	GO:0019722	9.85	TNF PTGDR2 FCGR3A CD4 CCR6
19	positive regulation of vitamin D biosynthetic process	GO:0060557	9.81	TNF IFNG
20	interleukin-17-mediated signaling pathway	GO:0097400	9.8	TRAF6 TRAF3IP2 IL17RA
21	positive regulation of cellular respiration	GO:1901857	9.73	IFNG IL10RB IL4
22	immune response	GO:0006955	9.7	CCL11 CCL5 CCR6 CD1E CD4 DEFB4A
23	positive regulation of receptor signaling pathway via JAK-STAT	GO:0046427	9.65	TNF IL5 IL10RB IL10RA CCL5