Folliculitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: FLL008 MIFTS: 47	Folliculitis Categories: Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Folliculitis

MalaCards integrated aliases for Folliculitis:

Name: Folliculitis ¹² ⁵⁵ ³ ⁴⁴ ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4409

MeSH ⁴⁴ D005499

NCIt ⁵⁰ C94408

SNOMED-CT ⁶⁸ 13600006

UMLS ⁷³ C0016436

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Summaries for Folliculitis

CDC : ³ Swimming and other water-related activities are excellent ways to get the physical activity and health benefits needed for a healthy life. However, they are not risk-free. CDC’s Healthy Swimming website provides information for all groups of individuals involved in a healthy and safe swimming experience about how to maximize the health benefits of swimming while minimizing the risk of illness and injury.

MalaCards based summary : Folliculitis is related to eosinophilic pustular folliculitis and dermatitis, and has symptoms including exanthema An important gene associated with Folliculitis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Lidocaine and Ketoconazole have been mentioned in the context of this disorder. Affiliated tissues include skin, neutrophil and bone, and related phenotype is immune system.

Wikipedia : ⁷⁶ Folliculitis is the infection and inflammation of one or more hair follicles. The condition may occur... more...

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Related Diseases for Folliculitis

Diseases related to Folliculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 287)

#	Related Disease	Score	Top Affiliating Genes
1	eosinophilic pustular folliculitis	34.3	IFNG PTGDR2
2	dermatitis	30.5	CCL11 IFNG IL4 IL5
3	viral infectious disease	30.0	CCL5 IFNG IL4
4	blepharitis	29.8	CCL11 SAT1
5	strongyloidiasis	29.8	CCL11 IFNG IL5
6	contact dermatitis	29.7	IFNG IL4 IL5
7	cutaneous leishmaniasis	29.7	IFNG IL4 IL5
8	leishmaniasis	29.7	IFNG IL4 IL5
9	orofacial granulomatosis	29.6	CCL5 IFNG IL4
10	tropical spastic paraparesis	29.6	CCL5 IFNG IL2RA
11	rheumatoid arthritis	29.6	CCL5 IFNG IL2RA IL4
12	pulmonary eosinophilia	29.4	CCL11 CCL5 IL4 IL5
13	psoriasis	29.4	CCL5 DEFB4A IFNG IL4
14	skin disease	29.1	CCL11 DEFB4A IFNG IL4 IL5
15	inflammatory bowel disease	28.8	CCL11 CCL5 DEFB4A IFNG IL4 IL5
16	quinquaud's decalvans folliculitis	12.6
17	tufted hair folliculitis	12.2
18	atrophoderma vermiculata	11.9
19	perifolliculitis capitis abscedens et suffodiens, familial	11.6
20	pyoderma	11.4
21	tinea barbae	11.4
22	pseudofolliculitis barbae	11.4
23	ulerythema ophryogenesis	11.0
24	alopecia	10.3
25	autoimmune myocarditis	10.2	IFNG IL4
26	b-cell growth factor	10.2	IFNG IL4
27	eosinophilic fasciitis	10.2	IFNG IL5
28	cephalosporin allergy	10.2	IFNG IL5
29	baylisascariasis	10.2	IFNG IL4
30	penicillin allergy	10.2	IFNG IL4
31	blepharoconjunctivitis	10.2	CCL11 IL4
32	crustacean allergy	10.2	IFNG IL4
33	pemphigoid gestationis	10.2	CCL11 IL5
34	papillary conjunctivitis	10.2	CCL11 IL4
35	lymphoma	10.2
36	giant papillary conjunctivitis	10.2	CCL11 IL4
37	large granular lymphocyte leukemia	10.2	IFNG IL2RA
38	chronic meningitis	10.2	CCL11 IL5
39	cardiac sarcoidosis	10.2	IFNG IL5
40	mikulicz disease	10.2	IL5 PTGDR2
41	eosinophilia-myalgia syndrome	10.2	IFNG IL5
42	ascaris lumbricoides infection	10.2	IFNG IL5
43	eosinophilic gastroenteritis	10.2	CCL11 IL5
44	cough variant asthma	10.2	IL4 IL5
45	chronic graft versus host disease	10.2	IFNG IL2RA
46	hypersplenism	10.2	IFNG IL4
47	egg allergy	10.2	IL4 IL5
48	hyper ige syndrome	10.2	IFNG IL4
49	sulfamethoxazole allergy	10.2	IL4 IL5
50	gaucher disease, type ii	10.2	IL4 IL5

Graphical network of the top 20 diseases related to Folliculitis:

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Symptoms & Phenotypes for Folliculitis

UMLS symptoms related to Folliculitis:

exanthema

MGI Mouse Phenotypes related to Folliculitis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	immune system	MP:0005387	9.23	CCL11 CCL5 EGF IFNG IL2RA IL4

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Drugs & Therapeutics for Folliculitis

Drugs for Folliculitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 112)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Lidocaine

Approved, Vet_approved

Phase 4,Early Phase 1,Not Applicable

137-58-6

3676

Ketoconazole

Approved, Investigational

Phase 4

65277-42-1

3823 47576

Miconazole

Approved, Investigational, Vet_approved

Phase 4

22916-47-8

4189

Clindamycin

Approved, Vet_approved

Phase 4

18323-44-9

29029

Cephalexin

Approved, Investigational, Vet_approved

Phase 4

15686-71-2

27447

Clobetasol

Approved, Experimental, Investigational

Phase 4,Phase 3

25122-46-7, 25122-41-2

5311051 32798

Tetracaine

Approved, Vet_approved

Phase 4,Not Applicable

94-24-6

5411

Prilocaine

Approved

Phase 4

721-50-6

4906

Calcitriol

Approved, Nutraceutical

Phase 4,Phase 3

32222-06-3

5280453 134070

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4,Phase 3,Phase 2,Not Applicable

Hormone Antagonists

Phase 4,Phase 3,Phase 2,Not Applicable

Hormones

Phase 4,Phase 3,Phase 2,Not Applicable

glucocorticoids

Phase 4,Phase 3,Phase 2,Not Applicable

Anti-Inflammatory Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Vasoconstrictor Agents

Phase 4,Phase 3,Early Phase 1

Central Nervous System Depressants

Phase 4,Early Phase 1

Anti-Arrhythmia Agents

Phase 4,Early Phase 1

Anesthetics, Local

Phase 4,Early Phase 1

Anesthetics

Phase 4,Early Phase 1

Diuretics, Potassium Sparing

Phase 4,Early Phase 1

Peripheral Nervous System Agents

Phase 4,Phase 3,Early Phase 1

Sodium Channel Blockers

Phase 4,Early Phase 1

Cytochrome P-450 CYP3A Inhibitors

Phase 4

Cytochrome P-450 Enzyme Inhibitors

Phase 4

Steroid Synthesis Inhibitors

Phase 4

Antifungal Agents

Phase 4

Anti-Infective Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Clindamycin palmitate

Phase 4

Anti-Bacterial Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Clindamycin phosphate

Phase 4

methicillin

Phase 4,Not Applicable

Micronutrients

Phase 4,Phase 3,Phase 2

Vitamins

Phase 4,Phase 3,Phase 2

Trace Elements

Phase 4,Phase 3,Phase 2

Bone Density Conservation Agents

Phase 4,Phase 3

Calcium, Dietary

Phase 4,Phase 3

EMLA

Phase 4

Apremilast

Approved, Investigational

Phase 3

608141-41-9

11561674

Clotrimazole

Approved, Vet_approved

Phase 2, Phase 3

23593-75-1

2812

Immunologic Factors

Phase 3,Not Applicable

Immunosuppressive Agents

Phase 3,Not Applicable

Respiratory System Agents

Phase 2, Phase 3,Early Phase 1

Dermatologic Agents

Phase 2, Phase 3

Anti-Asthmatic Agents

Phase 2, Phase 3,Early Phase 1

Angiogenesis Modulating Agents

Phase 3

Analgesics

Phase 3

Angiogenesis Inhibitors

Phase 3

Anti-Inflammatory Agents, Non-Steroidal

Phase 3

Analgesics, Non-Narcotic

Phase 3

Antirheumatic Agents

Phase 3

Interventional clinical trials:

(show all 31)

#	Name	Status	NCT ID	Phase	Drugs
1	Safety and Efficacy of Ketoconazole 2% Foam in the Treatment of Pityrosporum Folliculitis	Completed	NCT00824863	Phase 4	ketoconazole 2% foam
2	Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection	Completed	NCT01126268	Phase 4	Retapamulin (Altabax)
3	Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections	Completed	NCT00352612	Phase 4	clindamycin;cephalexin
4	Study of Wound Packing After Superficial Skin Abscess Drainage	Completed	NCT00746109	Phase 4
5	Efficacy/Safety/Subject Satisfaction/Duration of Response of Clobetasol Propionate Spray vs Ointment in Plaque Psoriasis	Completed	NCT00733954	Phase 4	clobetasol propionate spray;clobetasol propionate ointment
6	Evaluate Safety/Efficacy of Two Treatment Regimens for Vectical™ Ointment & Clobex® Spray for Moderate Plaque Psoriasis	Completed	NCT00988637	Phase 4	Vectical™ Ointment weekdays and Clobex® Spray weekends regimen;Clobex® Spray morning and Vectical™ Ointment evening regimen
7	Tape Versus Semirigid Versus Lace-up Ankle Support in the Treatment of Acute Lateral Ankle Ligament Injury.	Completed	NCT01126242	Phase 4
8	7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream	Completed	NCT02372786	Phase 4	2,5% lidocaine / 2,5% prilocaine cream;7% lidocaine / 7% tetracaine cream
9	The Efficacy of Laser Assisted Hair Removal in the Treatment of Acne Keloidalis Nuchae; a Pilot Study	Completed	NCT01548898	Phase 4
10	Safety & Effectiveness of Clobex Spray, Followed by Calcitriol Ointment in Management of Plaque Psoriasis	Completed	NCT00658788	Phase 3	clobetasol propionate spray 0.05%;calcitriol ointment
11	A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behcet's Disease	Active, not recruiting	NCT02307513	Phase 3	Apremilast (CC-10004);Placebo
12	Evaluation of Efficacy and Comparative Isolation of the Association Beclomethasone Clotrimzaol + + Gentamicin in Patients With Acne Contaminated	Suspended	NCT01244256	Phase 2, Phase 3	Clotrimazole + Gentamicin + Beclomethasone;Clotrimazole + Gentamicin
13	A Phase 2 Dose Ranging, Evaluator-Blinded Study to Evaluate the Safety of Topical IDP-118	Unknown status	NCT01670513	Phase 1, Phase 2	IDP-118 Low Strength;IDP-118 High Strength
14	Xia Shi Surgical Treatment for Eczema Multi-center Clinical Research	Unknown status	NCT02517957	Phase 2	Furoic acid loperamide hydrochloride cream;Mullite ointment;3% boric acid solution;Zine oxide
15	Investigation of the Effect of Vitamin K3-lotion for the Treatment of Cetuximab Induced Folliculitis	Completed	NCT01094444	Phase 2
16	Study About Preventive Treatment of Folliculitis Induced by Epidermal Growth Factor Receptor Inhibitors	Completed	NCT00910676	Phase 2	Diprosone
17	A Study of Management of Tarceva - Induced Rash in Patients With Non-Small Cell Lung Cancer.	Completed	NCT00531934	Phase 2	Doxycline;erlotinib [Tarceva]
18	Determination of the Efficacy and Safety of Psirelax in the Relief of the Disease in Psoriasis	Completed	NCT01000714	Phase 2	Psirelax
19	Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal Matrix	Completed	NCT00129428	Phase 1, Phase 2
20	Panitumumab Skin Toxicity Prevention Trial	Recruiting	NCT03167268	Phase 2	Lycopene
21	Safety and Pharmacokinetics Study of New Formulation of Bimatoprost in Patients With Alopecia	Completed	NCT01189279	Phase 1	bimatoprost Formulation A;bimatoprost Formulation B;bimatoprost Formulation C
22	NdYag Laser for Acne Keloidalis Nuchae	Unknown status	NCT00757315	Not Applicable	Topical corticosteroid alone
23	Reducing Side-effects of Autologous Skin Tissue Harvesting	Unknown status	NCT02234193	Early Phase 1
24	Impact of Staphylococcus Aureus on Folliculitis Decalvans	Completed	NCT02157688
25	An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection in Soldiers	Completed	NCT00289588	Not Applicable	Mupirocin (drug)
26	PCR (Polymerase Chain Reaction) Assay for Diagnosis of Sarcoptes Scabiei	Completed	NCT02254564
27	Fournier's Gangrene and the Origin of the Infection as a Prognostic of Morbidity and Mortality, an Analysis of 121 Patients	Completed	NCT03443544
28	Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy	Completed	NCT01328080	Not Applicable
29	Effectiveness of Laser Hair Removal in Pilonidal Disease	Recruiting	NCT03276065	Not Applicable
30	Trichoscopy in Diagnosis of Immunobollous Diseases	Not yet recruiting	NCT03478072
31	UVA1 Light for Scleroderma and Similar Conditions	Terminated	NCT00476697	Not Applicable

Search NIH Clinical Center for Folliculitis

Cochrane evidence based reviews: folliculitis

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Genetic Tests for Folliculitis

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Anatomical Context for Folliculitis

MalaCards organs/tissues related to Folliculitis:

⁴¹

Skin, Neutrophil, Bone, Bone Marrow, Lung, T Cells, B Cells

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Publications for Folliculitis

Articles related to Folliculitis:

(show top 50) (show all 885)

#	Title	Authors	Year
1	Do Cutibacterium acnes and Staphylococcus aureus define two different types of folliculitis?: Bacteriological study of scalp folliculitis. ( 29341254 )	Frenard C....Dreno B.	2018
2	Nilotinib-induced Perforating Folliculitis: Two Cases. ( 29769784 )	Saraswat N....Talukdar K.	2018
3	Lymphocytic Mural Folliculitis Resembling Epitheliotropic Lymphoma in Tigers ( Panthera tigris). ( 29661122 )	Sula M.M....Ramsay E.C.	2018
4	Atypical clinical presentations of Malassezia folliculitis: a retrospective analysis of 94 biopsy-proven cases. ( 29313953 )	Tsai Y.C....Wang Y.J.	2018
5	Primary cutaneous<i>Rhizopus</i>folliculitis in an immunocompetent woman. ( 29296649 )	Johnson V.E....Boyd A.S.	2018
6	Mycobacterium immunogenum folliculitis on the lower extremities of a healthy young adult. ( 29920742 )	McNeil E.P....Farah R.S.	2018
7	Malassezia: a case of coexisting pityriasis versicolor and Malassezia folliculitis. ( 29926112 )	Choi E....Aw D.	2018
8	Inflammasome Activation Characterizes Lesional Skin of Folliculitis Decalvans. ( 29542810 )	Eyraud A....Seneschal J.	2018
9	Primary cutaneous follicle center lymphoma mimicking folliculitis. ( 29529119 )	Chockalingam R....Patel A.B.	2018
10	Isotretinoin treatment for folliculitis decalvans: a retrospective case-series study. ( 29313960 )	Aksoy B....Mutlu E.	2018
11	Tumour necrosis factor-I+-inhibitor-induced neutrophilic folliculitis presenting with strong lesional expression of interleukin-36I^. ( 29315748 )	Werninghaus I....Wenzel J.	2018
12	Tinea Incognito with Folliculitis-Like Presentation: A Case Series. ( 29386843 )		2018
13	Impact of Folliculitis Decalvans on Quality of Life and Subjective Perception of Disease. ( 29457012 )		2018
14	A case of atypical eosinophilic pustular folliculitis that emerged following the administration of capecitabine. ( 29444365 )		2018
15	Diversity of Staphylococcus pseudintermedius in carriage sites and skin lesions of dogs with superficial bacterial folliculitis: potential implications for diagnostic testing and therapy. ( 29781542 )		2018
16	Folliculitis Decalvans: Effectiveness of Therapies and Prognostic Factors In A Multicenter Series of 60 Patients With Long-Term Follow-Up. ( 29864465 )		2018
17	In vivo characterization of pustules in Malassezia Folliculitis by reflectance confocal microscopy and optical coherence tomography. A case series study. ( 29484711 )		2018
18	Overexpression of NLRP3, NLRC4 and AIM2 inflammasomes and their priming-associated molecules (TLR2, TLR4, Dectin-1, Dectin-2 and NFI_B) in Malassezia folliculitis. ( 28976036 )		2018
19	The Prevalence of <i>Malassezia</i> Folliculitis in Patients with Papulopustular/Comedonal Acne, and Their Response to Antifungal Treatment. ( 29911526 )		2018
20	Pityrosporum folliculitis: A retrospective review of 110 cases. ( 29138059 )		2018
21	Clinical and trichoscopic correlation of primary neutrophilic scarring alopecia: folliculitis decalvans and dissecting cellulitis. ( 30229638 )	Rossi A...Fortuna MC	2018
22	Eosinophilic Pustular Folliculitis Associated with Cutaneous Angiosarcoma. ( 29271395 )	Jiang YY...Jin HZ	2018
23	Dissecting folliculitis (dissecting cellulitis) of the scalp: a 66-patient case series and proposal of classification. ( 30168900 )	Lee CN...Yang CC	2018
24	Creeping eruption and eosinophilic folliculitis: Atypical cutaneous larva migrans. ( 29328517 )	Lockmann A...M??ner R	2018
25	Eosinophilic pustular folliculitis with underlying mantle cell lymphoma. ( 30063774 )	Owen RL...Purcell SM	2018
26	Epidermolysis Bullosa Pruriginosa Associated with Folliculitis Decalvans: Case Report and Review of the Literature. ( 30410911 )	Rivitti-Machado MC...Doche I	2018
27	Folliculitis decalvans and orofacial granulomatosis. ( 30008653 )	M?ci?ska-Jundzi?? K...Czajkowski R	2018
28	Recalcitrant and recurrent bacterial folliculitis during anti-IL17 therapy in a psoriatic patient. ( 30019574 )	Sacchelli L...Bardazzi F	2018
29	Updates in therapeutics for folliculitis decalvans: A systematic review with evidence-based analysis. ( 30092322 )	Rambhia PH...Bergfeld W	2018
30	Dermoscopy of Pityrosporum Folliculitis. ( 30244060 )	Jakhar D...Chaudhary R	2018
31	A case of necrotizing infundibular crystalline folliculitis. ( 30251266 )	Yim S...Chae SW	2018
32	A Case of Perforating Folliculitis Induced by Vemurafenib. ( 30281138 )	Shiraishi K...Sayama K	2018
33	Linear Circumscribed Scleroderma-Like Folliculitis Decalvans: Yet Another Face of a Protean Condition. ( 30386078 )	Rezende HD...Tre?b RM	2018
34	Persistent Folliculitis in An Immunocompetent Child. ( 30387251 )	Wen SC...Gwee A	2018
35	Adipose tissue transplant in recurrent folliculitis decalvans. ( 30482066 )	Tedesco M	2018
36	Sparing of the scalp in severe Demodex folliculitis after stem cell transplantation. ( 30510997 )	Chen C...Gallitano SM	2018
37	REPLY to JAAD-D-18-01922: ''Folliculitis decalvans: Effectiveness of therapies and prognostic factors in a multicenter series of 60 patients with long-term follow-up''. ( 30528500 )	Miguel-G?mez L...Va??-Galv?n S	2018
38	Comment on ''Folliculitis decalvans: Effectiveness of therapies and prognostic factors in a multicenter series of 60 patients with long-term follow-up''. ( 30528502 )	Litaiem N...Zeglaoui F	2018
39	Systemic photodynamic therapy in folliculitis decalvans. ( 28940572 )	Collier NJ...Allan E	2018
40	Utility of Gram staining for diagnosis of Malassezia folliculitis. ( 29131371 )	Tu WT...Shih YH	2018
41	Perforating folliculitis in association with liver impairment in a patient with chronic ductopenic rejection of liver transplant. ( 29777542 )	Steele L...Wakelin S	2018
42	Classic form of eosinophilic pustular folliculitis in an immunocompetent girl: rapid and complete resolution after low-dose oral indomethacin treatment. ( 29447640 )	Monastirli A....Tsambaos D.	2017
43	Disseminate recurrent folliculitis as the presenting picture of hidradenitis suppurativa. ( 28838562 )	Revuz J.	2017
44	Perforating Folliculitis Secondary to Bendamustine-Rituximab Chemotherapy: A Case Report. ( 28761855 )	Monteiro R....Rajlakshmi T.	2017
45	A Case of Congenital Folliculitis Caused by Pseudomonas aeruginosa in a Preterm Neonate. ( 28250259 )	Matsui K....Kondo M.	2017
46	Folliculitis, Tufted Hair ( 28613486 )	Hughes E.C.	2017
47	Crystalline folliculitis revealed by non-aqueous staining technique. ( 29469700 )	Siscos S.M....Fraga G.	2017
48	Folliculitis caused by Staphylococcus epidermidis? ( 28712270 )	Veraldi S....Grancini A.	2017
49	Lichenoid folliculitis: A unifying concept. ( 28345255 )	Turegano M.M....Sperling L.C.	2017
50	Necrotizing eosinophilic folliculitis: a new manifestation of the atopic diathesis? ( 27910130 )	Cunningham F....Magro C.M.	2017

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Genes for Folliculitis

Genes related to Folliculitis (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	23.94	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	11501668
2	IFNG	Interferon Gamma	Protein Coding	21.11	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	PTGDR2	Prostaglandin D2 Receptor 2	Protein Coding	21.09	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	IL4	Interleukin 4	Protein Coding	20.61	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	IL5	Interleukin 5	Protein Coding	20.4	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	DEFB4A	Defensin Beta 4A	Protein Coding	19.83	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	12534631 15149502
7	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	16.64	GeneCards inferred via : Publications (show sections)
8	EGF	Epidermal Growth Factor	Protein Coding	16.64	GeneCards inferred via : Publications (show sections)
9	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	16.64	GeneCards inferred via : Publications (show sections)
10	FCGR3A	Fc Fragment Of IgG Receptor IIIa	Protein Coding	16.64	GeneCards inferred via : Publications (show sections)
11	SAT1	Spermidine/Spermine N1-Acetyltransferase 1	Protein Coding	16.16	DISEASES inferred ¹⁵

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Variations for Folliculitis

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Expression for Folliculitis

Search GEO for disease gene expression data for Folliculitis.

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Pathways for Folliculitis

Pathways related to Folliculitis according to GeneCards Suite gene sharing:

(show all 37)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁶ Show member pathways Immune System ⁶⁶ Neutrophil degranulation ⁶⁶	13.82	CCL11 CCL5 DEFB4A EGF FCGR3A IFNG
2	TGF-Beta Pathway ⁶⁴ Show member pathways JAK-STAT Pathway ⁶⁴ JNK Pathway ⁶⁴ MAPK Family Pathway ⁶⁴ Regulation of eIF4 and p70S6K ⁶⁴ SOCS Pathway ⁶⁴	13.37	CCL11 CCL5 EGF IFNG IL2RA IL4
3	Akt Signaling ⁶⁴ Show member pathways p38 Signaling ⁶⁴ Tec Kinases Signaling ⁶⁴	13.26	CCL11 CCL5 EGF IL2RA IL4 IL5
4	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.16	CCL11 CCL5 EGF IFNG IL2RA IL4
5	PAK Pathway ⁶⁴ Show member pathways Antioxidant Action of Vitamin-C ⁶⁴ Epithelial Adherens Junctions ⁶⁴	13.15	CCL11 CCL5 EGF IL2RA IL4 IL5
6	Allograft rejection ¹ ³⁷ Show member pathways Antigen processing and presentation ³⁷ Asthma ³⁷ Autoimmune thyroid disease ³⁷ CTL Mediated Apoptosis ⁶⁴ Graft-versus-host disease ³⁷ Intestinal immune network for IgA production ³⁷ THC Differentiation Pathway ⁶⁴ Type I diabetes mellitus ³⁷ Viral myocarditis ³⁷	12.75	CCL11 IFNG IL2RA IL4 IL5
7	Pathways in cancer ³⁷	12.69	EGF IFNG IL2RA IL4 IL5
8	Influenza A ³⁷ Show member pathways Herpes simplex infection ³⁷ Measles ³⁷	12.65	CCL5 IFNG IL2RA IL4
9	Th17 cell differentiation ³⁷ Show member pathways IL-22 Pathway ⁶⁴ Immune response IL-22 signaling pathway ²² Inflammatory bowel disease (IBD) ³⁷ Th1 and Th2 cell differentiation ³⁷	12.48	IFNG IL2RA IL4 IL5
10	NF-kappaB Signaling ⁴	12.44	CCL5 IFNG IL2RA IL4
11	JAK-STAT signaling pathway (KEGG) ³⁷ Show member pathways Interleukin-19, 20, 22, 24 ⁶⁶ Jak/STAT Signaling Pathway ⁶⁵	12.24	EGF IFNG IL2RA IL4 IL5
12	Selenium Micronutrient Network ¹ Show member pathways Folate Metabolism ¹ Metabolism of ingested MeSeO2H into MeSeH ⁶⁶ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	12.18	CCL5 IFNG IL4
13	IL-17 Family Signaling Pathways ⁶⁵ Show member pathways IL17 signaling pathway ¹ IL-17 signaling pathway ³⁷ Interleukin-17 signaling ⁶⁶ Mucin expression in CF via IL-6, IL-17 signaling pathways ²²	12.16	CCL11 DEFB4A IFNG IL4 IL5
14	Immune response IFN alpha/beta signaling pathway ²² Show member pathways Cytokine Network ⁶⁴ Interferon alpha/beta signaling ⁶⁶ Regulation of IFNA signaling ⁶⁶	12.15	IFNG IL2RA IL4 IL5
15	Toxoplasmosis ³⁷ Show member pathways Leishmaniasis ³⁷	12.11	FCGR3A IFNG IL4
16	Bacterial infections in CF airways ²² Show member pathways IL-1 beta-dependent CFTR expression ²² Immune response Bacterial infections in normal airways ²² Immune response TLR signaling pathways ²²	12.07	CCL11 DEFB4A IFNG IL4
17	Microglia Activation During Neuroinflammation: Overview ⁶⁵ Show member pathways Microglia Activation During Neuroinflammation: Microglia Activation ⁶⁵	11.93	FCGR3A IFNG IL4
18	IL12-mediated signaling events ¹ Show member pathways Immune response IL-12-induced IFN-gamma production ²²	11.88	IFNG IL2RA IL4
19	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.83	IFNG IL2RA IL4 IL5 PTGDR2
20	Hematopoietic cell lineage ³⁷	11.79	IL2RA IL4 IL5
21	Jak-Stat Signaling Pathway (sino) ⁶⁷	11.77	EGF IFNG IL2RA
22	Glucocorticoid receptor regulatory network ¹	11.71	IFNG IL4 IL5
23	Calcineurin-regulated NFAT-dependent transcription in lymphocytes ¹ Show member pathways Calcium signaling in the CD4+ TCR pathway ¹	11.64	IFNG IL2RA IL4 IL5
24	Innate Lymphoid Cell Differentiation Pathways ⁶⁵	11.62	IFNG IL2RA IL4 IL5 PTGDR2
25	IL4-mediated signaling events ¹	11.57	CCL11 IL4 IL5
26	Microglia Activation During Neuroinflammation: Microglia Polarization ⁶⁵	11.51	CCL11 CCL5 FCGR3A IFNG IL4
27	Immune response IFN gamma signaling pathway ²² Show member pathways IFN-gamma pathway ¹	11.51	CCL11 CCL5 EGF IFNG IL2RA IL4
28	Lung fibrosis ¹	11.35	CCL11 CCL5 EGF IL4 IL5
29	Development and heterogeneity of the ILC family ¹	11.22	IFNG IL4 IL5
30	Inflammatory Response Pathway ¹	11.22	IFNG IL2RA IL4 IL5
31	Cytokines and Inflammatory Response ¹	11.16	IFNG IL4 IL5
32	Immune response_IL-12 signaling pathway ²² Show member pathways Interleukin-12 signaling ⁶⁶	11.13	IFNG IL2RA
33	IL12 signaling mediated by STAT4 ¹	11.11	IFNG IL2RA
34	G-protein signaling_RhoB regulation pathway ²²	11.09	CCL11 CCL5 IL4 IL5
35	OX40 Pathway ⁶⁴	11.09	IFNG IL4 IL5
36	G-protein signaling_Rap2B regulation pathway ²²	10.89	CCL11 CCL5 EGF IL4 IL5
37	Th2 Differentiation Pathway ⁶⁵	10.68	CCL11 IFNG IL2RA IL4 IL5

Sources

GO Terms for Folliculitis

Cellular components related to Folliculitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.7	CCL11 CCL5 DEFB4A EGF IFNG IL4
2	extracellular space	GO:0005615	9.5	CCL11 CCL5 DEFB4A EGF IFNG IL4
3	intracellular	GO:0005622	9.17	CCL11 DEFB4A IFNG IL2RA IL5 PTGDR2

Biological processes related to Folliculitis according to GeneCards Suite gene sharing:

(show all 16)

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of cell migration	GO:0030335	9.73	CCL11 CCL5 EGF
2	regulation of signaling receptor activity	GO:0010469	9.65	CCL11 CCL5 IFNG IL4 IL5
3	MAPK cascade	GO:0000165	9.62	CCL5 EGF IL2RA IL5
4	response to virus	GO:0009615	9.61	CCL11 CCL5 IFNG
5	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	9.58	CCL5 IFNG IL4
6	lymphocyte chemotaxis	GO:0048247	9.55	CCL11 CCL5
7	positive regulation of phosphorylation	GO:0042327	9.54	CCL5 EGF
8	positive regulation of T cell proliferation	GO:0042102	9.54	CCL5 IL2RA IL4
9	ERK1 and ERK2 cascade	GO:0070371	9.52	CCL11 EGF
10	positive regulation of JAK-STAT cascade	GO:0046427	9.51	CCL5 IL5
11	eosinophil chemotaxis	GO:0048245	9.49	CCL11 CCL5
12	positive regulation of T cell differentiation	GO:0045582	9.48	IL2RA IL4
13	regulation of regulatory T cell differentiation	GO:0045589	9.46	IFNG IL2RA
14	chemotaxis	GO:0006935	9.46	CCL11 CCL5 DEFB4A PTGDR2
15	cytokine-mediated signaling pathway	GO:0019221	9.35	CCL11 CCL5 IL2RA IL4 IL5
16	immune response	GO:0006955	9.28	CCL11 CCL5 DEFB4A FCGR3A IFNG IL2RA

Molecular functions related to Folliculitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	growth factor activity	GO:0008083	9.33	EGF IL4 IL5
2	chemoattractant activity	GO:0042056	9.32	CCL5 DEFB4A
3	CCR chemokine receptor binding	GO:0048020	9.26	CCL11 CCL5
4	Ras guanyl-nucleotide exchange factor activity	GO:0005088	9.13	EGF IL2RA IL5
5	cytokine activity	GO:0005125	9.02	CCL11 CCL5 IFNG IL4 IL5

Sources

Sources for Folliculitis

¹ BioSystems

² BitterDB

³ CDC

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⁵¹ NDF-RT

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⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

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⁶⁶ Reactome

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⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia