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MCID: FDL002
MIFTS: 55

Food Allergy

Categories: Immune diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Food Allergy

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MalaCards integrated aliases for Food Allergy:

Name: Food Allergy 12 43 15 73
Food Hypersensitivity 12 44
Food Allergies 63
Allergy Food 55

Classifications:

MalaCards categories:
Anatomical: Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:3044
MeSH 44 D005512
UMLS 73 C0016470
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Summaries for Food Allergy

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MedlinePlus : 43 Food allergy is an abnormal response to a food triggered by your body's immune system. In adults, the foods that most often trigger allergic reactions include fish, shellfish, peanuts, and tree nuts, such as walnuts. Problem foods for children can include eggs, milk, peanuts, tree nuts, soy, and wheat. The allergic reaction may be mild. In rare cases it can cause a severe reaction called anaphylaxis. Symptoms of food allergy include Itching or swelling in your mouth Vomiting, diarrhea, or abdominal cramps and pain Hives or eczema Tightening of the throat and trouble breathing Drop in blood pressure Your health care provider may use a detailed history, elimination diet, and skin and blood tests to diagnose a food allergy. When you have food allergies, you must be prepared to treat an accidental exposure. Wear a medical alert bracelet or necklace, and carry an auto-injector device containing epinephrine (adrenaline). You can only prevent the symptoms of food allergy by avoiding the food. After you and your health care provider have identified the foods to which you are sensitive, you must remove them from your diet. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Food Allergy, also known as food hypersensitivity, is related to egg allergy and peanut allergy. An important gene associated with Food Allergy is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Pathways in cancer. The drugs Epinephrine and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and tongue, and related phenotypes are endocrine/exocrine gland and hematopoietic system

Disease Ontology : 12 A hypersensitivity reaction type I disease that is an abnormal response to a food, triggered by the body's immune system.

PubMed Health : 63 About food allergies: If someone keeps having the same reaction (e.g. nausea, a rash or feeling unwell) after eating certain foods, it may be logical to assume that they have a food allergy.But food allergies are actually less common than many people believe: The symptoms are often caused by something else instead. It’s important to get the right diagnosis in order to get the right treatment – and avoid removing certain foods from your diet for no reason.

Wikipedia : 76 A food allergy is an abnormal immune response to food. The signs and symptoms may range from mild to... more...

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Related Diseases for Food Allergy

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Diseases related to Food Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 238)
# Related Disease Score Top Affiliating Genes
1 egg allergy 32.8 IL4 IL5
2 peanut allergy 32.2 FLG IFNG IL10 IL13
3 fruit allergy 32.1 CETP MS4A2 SCP2
4 esophagitis, eosinophilic, 1 32.1 FLG IL13 IL5 STAT6
5 angioimmunoblastic lymphadenopathy with dysproteinemia 30.7 IL13 IL5
6 colitis 30.3 FOXP3 IFNG IL10 IL4
7 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 30.2 FOXP3 IFNG IL10
8 dermatitis 30.2 FLG IFNG IL13 IL4 IL5 RNASE3
9 pneumonia 30.1 IL10 IL13 IL5
10 rhinitis 29.8 EPX IL13 IL4 IL5 RNASE3
11 milk allergy 29.8 CSN1S1 CSN3 IL10 IL4 IL5 RNASE3
12 eosinophilic gastroenteritis 29.7 ALB EPX IL5 RNASE3
13 fascioliasis 29.7 ALB IFNG IL10
14 contact dermatitis 29.4 FLG IFNG IL10 IL4 IL5
15 autoimmune disease 29.4 FOXP3 IFNG IL10 IL4 IL5
16 celiac disease 1 29.1 ALB FOXP3 IFNG IL10
17 gastroenteritis 29.0 ALB IFNG IL10 IL4 IL5 RNASE3
18 apple allergy 28.6 FOXP3 IL10 IL13 IL4 IL5 SCP2
19 allergic rhinitis 27.7 EPX IFNG IL10 IL13 IL4 IL5
20 asthma 27.1 EPX FLG IFNG IL10 IL13 IL4
21 allergic asthma 26.9 EPX IFNG IL10 IL13 IL4 IL5
22 dermatitis, atopic 26.6 CSN1S1 EPX FLG IFNG IL10 IL13
23 ige responsiveness, atopic 26.2 CSN1S1 FLG IFNG IL10 IL13 IL4
24 allergic hypersensitivity disease 26.2 CSN1S1 EPX FLG IFNG IL10 IL13
25 erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper-ige 11.6
26 fish allergy 11.2
27 aphthous stomatitis 11.2
28 tropical endomyocardial fibrosis 10.9 IL10 IL4
29 loeffler endocarditis 10.9 IL5 RNASE3
30 loeys-dietz syndrome 1 10.9
31 wheat allergy 10.9
32 eosinophilic cystitis 10.9
33 cytokine deficiency 10.9 IL13 IL5
34 mycoplasmal pneumonia 10.8 IFNG IL4
35 tungiasis 10.8 IL10 IL4
36 blepharoconjunctivitis 10.8 IL4 RNASE3
37 endomyocardial fibrosis 10.8 IL10 IL4
38 immunoglobulin a deficiency 1 10.8 IL10 IL4
39 ascaridiasis 10.8 IL10 IL13
40 eosinophilic fasciitis 10.8 IFNG IL5
41 cough variant asthma 10.7 IL4 IL5 RNASE3
42 intrinsic asthma 10.7 IL4 IL5 RNASE3
43 respiratory syncytial virus infectious disease 10.7 IL13 IL5
44 gastrointestinal allergy 10.7 IL4 IL5 RNASE3
45 kimura disease 10.7 IL4 IL5 RNASE3
46 cow milk allergy 10.7 IL10 IL5 RNASE3
47 acute necrotizing encephalitis 10.7 FOXP3 IFNG
48 necatoriasis 10.7 IL10 IL5
49 b-cell growth factor 10.7 IFNG IL4
50 paragonimiasis 10.7 IL13 IL5 RNASE3

Graphical network of the top 20 diseases related to Food Allergy:



Diseases related to Food Allergy
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Symptoms & Phenotypes for Food Allergy

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MGI Mouse Phenotypes related to Food Allergy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.97 IFNG STAT6 IL10 ALB IL13 CSN3
2 hematopoietic system MP:0005397 9.97 MS4A2 IFNG STAT6 IL10 IL13 EPX
3 immune system MP:0005387 9.96 MS4A2 SCP2 IL10 STAT6 IL13 EPX
4 digestive/alimentary MP:0005381 9.95 IFNG IL10 ALB IL13 IL4 FOXP3
5 integument MP:0010771 9.7 IFNG STAT6 IL10 CSN3 IL13 IL4
6 liver/biliary system MP:0005370 9.56 SCP2 IL10 STAT6 ALB IL4 FOXP3
7 respiratory system MP:0005388 9.17 IL10 STAT6 IL13 IL4 FOXP3 IL5
Sources

Drugs & Therapeutics for Food Allergy

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PubMedHealth treatment related to Food Allergy: 63

The main thing people can do to prevent allergic reactions is avoid the food that causes them.Medication is generally only used in acute situations, if people have a more severe allergic reaction. It doesn’t tend to be used for the long-term treatment of food allergies.Anaphylactic reactions are treated using emergency kits. These contain medications to reduce severe allergic reactions and prevent them from getting worse.

Drugs for Food Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 193)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4,Not Applicable 51-43-4 5816
2
Racepinephrine Approved Phase 4,Not Applicable 329-65-7 838
3
Montelukast Approved Phase 4 158966-92-8 5281040
4
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
5
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
6
Fluticasone Approved, Experimental, Investigational Phase 4,Not Applicable 90566-53-3 62924
7
Pimecrolimus Approved, Investigational Phase 4 137071-32-0 6447131 17753757
8
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
9
Caffeine Approved, Nutraceutical Phase 4 58-08-2 2519
10
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 1406-16-2
11 English walnut Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Not Applicable
12
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2 50-14-6 5280793
13
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 2 67-97-0 6221 5280795
14
BCG vaccine Investigational Phase 4,Phase 3
15 Analgesics Phase 4,Phase 1,Early Phase 1
16 Analgesics, Non-Narcotic Phase 4,Phase 1,Early Phase 1
17 Anti-Inflammatory Agents Phase 4,Phase 2,Early Phase 1,Not Applicable
18 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Early Phase 1
19 Antirheumatic Agents Phase 4,Phase 3,Early Phase 1
20 Calcium, Dietary Phase 4
21 Mesalamine Phase 4 89-57-6
22 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
23 Anti-Asthmatic Agents Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
24 Respiratory System Agents Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
25 Vaccines Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
26 Micronutrients Phase 4,Phase 2,Phase 1,Not Applicable
27 Trace Elements Phase 4,Phase 2,Phase 1,Not Applicable
28 Vitamins Phase 4,Phase 2,Phase 1,Not Applicable
29 Adrenergic Agents Phase 4,Not Applicable
30 Adrenergic Agonists Phase 4,Not Applicable
31 Adrenergic alpha-Agonists Phase 4,Not Applicable
32 Adrenergic beta-Agonists Phase 4,Not Applicable
33 Autonomic Agents Phase 4,Phase 2,Not Applicable
34 Bronchodilator Agents Phase 4,Phase 2,Not Applicable
35 Epinephryl borate Phase 4,Not Applicable
36 Mydriatics Phase 4,Not Applicable
37 Neurotransmitter Agents Phase 4,Phase 2,Not Applicable
38 Vasoconstrictor Agents Phase 4,Not Applicable
39 Dermatologic Agents Phase 4,Phase 2,Phase 1,Not Applicable
40 Hormone Antagonists Phase 4,Phase 2
41 Hormones Phase 4,Phase 2
42 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
43 Leukotriene Antagonists Phase 4
44 Antacids Phase 4,Not Applicable
45 Anti-Ulcer Agents Phase 4,Not Applicable
46 diuretics Phase 4
47 Gastrointestinal Agents Phase 4,Not Applicable
48 Natriuretic Agents Phase 4
49 Proton Pump Inhibitors Phase 4,Not Applicable
50 Adjuvants, Immunologic Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 357)
# Name Status NCT ID Phase Drugs
1 Clinical Management of Childhood Intestinal Lymphoid Nodular Hyperplasia Unknown status NCT01789294 Phase 4 Mesalamine
2 Growth, Safety and Tolerance of a Rice Protein Hydrolysate Formula in Infants With Cow's Milk Protein Allergy Unknown status NCT02405923 Phase 4
3 Effects of Montelukast in Asthmatic Children With and Without Food Allergy Completed NCT01618929 Phase 4 Montelukast
4 iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions Completed NCT02552537 Phase 4 Omeprazole;Placebo
5 Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens Completed NCT00557284 Phase 4 Montelukast;Placebo
6 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
7 A Phase-IV, Open-label Study to Evaluate Safety/Tolerability of Once-daily AVAMYS (TM) Aqueous Nasal Spray 110mcg Among Vietnamese Adult Patients With Established Perennial Allergic Rhinitis Completed NCT01270958 Phase 4 Avamys aqueous nasal spray 110mcg
8 NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants Completed NCT03219931 Phase 4 Bifidobacterium breve BR03 and Bifidobacterium breve B632;Placebos
9 Safety of Nasal Influenza Immunisation in Egg Allergic Children - The SNIFFLE 2 Study Completed NCT02111512 Phase 4 Administration of Live attenuated influenza vaccine (LAIV)
10 Safety of Oral Immunotherapy for Cow's Milk Allergy in School-aged Children Completed NCT01361347 Phase 4
11 Can Vitamin D Supplementation in Infants Prevent Food Allergy in the First Year of Life? The VITALITY Trial Recruiting NCT02112734 Phase 4 Vitamin D;placebo
12 Basophil Activation Test (BAT) Sensitivity in Child Food Allergy Recruiting NCT01966640 Phase 4
13 Pharmacokinetics of Intramuscular Adrenaline in Food--Allergic Teenagers Recruiting NCT03366298 Phase 4
14 Safety and Efficacy of Pimecrolimus Cream 1% in Atopic Disease Modification Terminated NCT00124709 Phase 4 Pimecrolimus;Corticosteroid
15 Parmigiano-Reggiano Cheese as a Possible Strategy to Acquire Oral Tolerance in Children With Cow's Milk Allergy Unknown status NCT02081651 Phase 3
16 Use of Probiotic Bacteria in Prevention of Allergic Disease in Children 1999-2008 Unknown status NCT00298337 Phase 2, Phase 3 Mixture of probiotic bacteria and prebiotic oligosaccharide
17 Peanut Oral Induction Tolerance in Peanut's Allergic Teenagers Unknown status NCT02046083 Phase 2, Phase 3 arachid
18 Prebiotics in Prevention of Atopy Completed NCT02116452 Phase 3
19 Efficacy and Safety of Viaskin Peanut in Children With Immunoglobulin E (IgE)-Mediated Peanut Allergy Completed NCT02636699 Phase 3
20 GP2013 Treatment in Patients With Active Rheumatoid Arthritis, Previously Treated With Rituxan® or MabThera® Completed NCT02514772 Phase 3
21 Evaluation of the Hypoallergenicity of an Extensively Hydrolyzed Formula Completed NCT02711163 Phase 3
22 Cow Milk Allergy: Evaluation of the Efficacy of a New Thickened Extensively Hydrolyzed Formula in Infants With Confirmed Cow Milk Allergy Completed NCT02351531 Phase 3
23 PALISADE Follow-on Study (ARC004) Recruiting NCT02993107 Phase 3
24 Follow-up of the PEPITES Study to Evaluate Long-term Efficacy and Safety of Viaskin Peanut in Children Active, not recruiting NCT03013517 Phase 3 Viaskin Peanut 250µg
25 Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction Active, not recruiting NCT01906853 Phase 3
26 ARTEMIS Peanut Allergy In Children Active, not recruiting NCT03201003 Phase 3
27 Safety Study of Viaskin Peanut to Treat Peanut Allergy Active, not recruiting NCT02916446 Phase 3
28 Peanut Allergy Oral Immunotherapy Study of AR101 for Desensitization in Children and Adults (PALISADE) Active, not recruiting NCT02635776 Phase 3
29 Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Young Children 1-3 Years of Age Active, not recruiting NCT03211247 Phase 3
30 Real-World AR101 Market-Supporting Experience Study in Peanut-Allergic Children Active, not recruiting NCT03126227 Phase 3
31 AR101 Real-World Open-Label Extension Study Enrolling by invitation NCT03337542 Phase 3
32 Long-term Safety Study of AR101 in Subjects Who Participated in a Prior AR101 Study (ARC008) Enrolling by invitation NCT03292484 Phase 3
33 Improving the Safety of Oral Immunotherapy in Cow's Milk Allergy Not yet recruiting NCT02216175 Phase 2, Phase 3
34 Therapeutic Effect of Chinese Herbal Medicine on Food Allergy Unknown status NCT00602160 Phase 2 FAHF-2 (TM)
35 The Effect of Extrinsic Factors on Food Allergy Unknown status NCT01429896 Phase 2
36 Treatment of Severe Peanut Allergy With Xolair (Omalizumab) and Oral Immunotherapy Unknown status NCT02402231 Phase 2 Omalizumab
37 Study to Assess Hypoallergenicity of a New Amino-acid Based Infant Formula in Children With Cow's Milk Allergy Unknown status NCT02414243 Phase 2
38 Evaluation of the Efficacy of a New Infant Formula in Subjects With Cow's Milk Allergy Unknown status NCT02149134 Phase 2
39 Epigenetic Effects Elicited By Lactobacillus GG In Children With Cow's Milk Allergy Unknown status NCT02062476 Phase 2
40 Pilot Study to Evaluate the Effect of Ketotifen on the Adverse Events Associated With Peanut Desensitization Unknown status NCT01625715 Phase 2 Ketotifen
41 FluMist in Egg Allergic Patients Unknown status NCT01248208 Phase 1, Phase 2
42 FAST-Fish -Food Allergy Specific Treatment for Fish Allergy. Completed NCT02017626 Phase 1, Phase 2
43 Multi Immunotherapy to Test Tolerance and Xolair Completed NCT02626611 Phase 2 Omalizumab;Food Flour Buildup
44 An Autism Study Using Nambudripad's Food Allergy Elimination Treatments Completed NCT00247156 Phase 1, Phase 2
45 Study Using Xolair in Rush Multi Oral Immunotherapy in Multi Food Allergic Patients Completed NCT02643862 Phase 1, Phase 2 Xolair;Placebo
46 OIT and Xolair® (Omalizumab) in Cow's Milk Allergy Completed NCT01157117 Phase 2 Milk powder
47 Study of Milk Allergy and Tolerance in Children Completed NCT00778258 Phase 2
48 FAST Fish Phase IIb Clinical Trial for the Treatment of Fish Allergy by Subcutaneous Immunotherapy Completed NCT02382718 Phase 2
49 Oral Immunotherapy for Childhood Egg Allergy Completed NCT00461097 Phase 2 Egg oral immunotherapy;Control Group
50 A Randomized, Double-Blind Placebo-Controlled Peanut Sublingual Immunotherapy Trial Completed NCT00580606 Phase 1, Phase 2 Glycerinated peanut allergenic extract;Placebo for peanut extract (glycerin)

Search NIH Clinical Center for Food Allergy

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: food hypersensitivity

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Genetic Tests for Food Allergy

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Anatomical Context for Food Allergy

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MalaCards organs/tissues related to Food Allergy:

41
Testes, Skin, Tongue, T Cells, B Cells, Liver, Bone
Sources

Publications for Food Allergy

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Articles related to Food Allergy:

(show top 50) (show all 854)
# Title Authors Year
1
The Challenges of Preventing Food Allergy: lessons learned from LEAP and EAT. ( 29909054 )
2018
2
The role of gastrointestinal permeability in food allergy. ( 29803708 )
2018
3
Factors Affecting Food Allergy-Related Quality of Life From Parents' Perception in Turkish Children. ( 29949834 )
2018
4
A new approach to oral allergen immunotherapy for food allergy? ( 29947140 )
2018
5
IgE-expressing memory B cells and plasmablasts are increased in blood of children with asthma, food allergy and atopic dermatitis. ( 29380876 )
2018
6
The Genetics of Food Allergy. ( 29374367 )
2018
7
Benefits of school nurse training sessions for food allergy and anaphylaxis management. ( 29807143 )
2018
8
Social media as a tool for the management of food allergy in children. ( 29411703 )
2018
9
Fecal Microbiome and Food Allergy in Pediatric Atopic Dermatitis: A Cross-Sectional Pilot Study. ( 29393195 )
2018
10
Food Allergy Training for Schools and Restaurants (The Food Allergy Community Program): Protocol to Evaluate the Effectiveness of a Web-Based Program. ( 29895510 )
2018
11
How Different Parts of the World Provide New Insights Into Food Allergy. ( 29949829 )
2018
12
Enhancing the Safety and Efficacy of Food Allergy Immunotherapy: a Review of Adjunctive Therapies. ( 29968170 )
2018
13
Phenotypes and endotypes of food allergy: a path to better understanding the pathogenesis and prognosis of food allergy. ( 29378246 )
2018
14
Oral Immunotherapy for Food Allergy -The FAST perspective. ( 29928983 )
2018
15
Protocol for Pertussis Immunisation and Food Allergy (PIFA): a case-control study of the association between pertussis vaccination in infancy and the risk of IgE-mediated food allergy among Australian children. ( 29391374 )
2018
16
From the pages of allergywatch recent advances in food allergy prevention and treatment. ( 29409852 )
2018
17
Study of the allergenic potential of Bacillus thuringiensis Cry1Ac toxin following intra-gastric administration in a murine model of food-allergy. ( 29886072 )
2018
18
Safety and Efficacy of Epicutaneous Immunotherapy for Food Allergy. ( 29369411 )
2018
19
Skin prick test analysis reveals cross-sensitization to tomato profilin and grass pollen in nasobronchialallergic patients with history of tomato food allergy. ( 29350017 )
2018
20
Global perspectives on food allergy. ( 29398243 )
2018
21
Quail egg homogenate alleviates food allergy induced eosinophilic esophagitis like disease through modulating PAR-2 transduction pathway in peanut sensitized mice. ( 29348584 )
2018
22
Accidental food allergy reactions: products and undeclared ingredients. ( 29908992 )
2018
23
On the reliability of the CD123-endowed basophil activation test (BAT) and its application in food allergy. ( 29905025 )
2018
24
Goals and Motivations of Families Pursuing Oral Immunotherapy for Food Allergy. ( 29936191 )
2018
25
Very early introduction of semisolid foods in preterm infants does not increase food allergies or atopic dermatitis. ( 29981439 )
2018
26
Behavioral risks associated with food allergy management in an urban pediatric population. ( 29371074 )
2018
27
Food allergy and anaphylaxis. ( 29950871 )
2018
28
Evaluation of food allergy candidate loci in the Genetics of Food Allergy Study. ( 29969633 )
2018
29
The importance of food allergy to the practicing clinician. ( 29391200 )
2018
30
Food Allergy Perceptions and Health-Related Quality of Life in a Racially Diverse Sample. ( 29882771 )
2018
31
Risk Factors for Food Allergy in Early Adolescence: The SchoolNuts Study. ( 29397374 )
2018
32
Impact of Food Allergy on the Growth of Children with Moderate-Severe Atopic Dermatitis. ( 29378286 )
2018
33
The Atopic Dermatitis and Food Allergy: A Paediatric Approach. ( 29895253 )
2018
34
Peptide and Recombinant Allergen Vaccines for Food Allergy. ( 29368278 )
2018
35
The environment and food allergy. ( 29410214 )
2018
36
Animal models of allergen-specific immunotherapy in food allergy: Overview and opportunities. ( 29920810 )
2018
37
Increased prevalence of eating disorders as a biopsychosocial implication of food allergy. ( 29944672 )
2018
38
Activated leucocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy. ( 29363753 )
2018
39
Mast cell heterogeneity underlies different manifestations of food allergy in mice. ( 29370173 )
2018
40
Corrigendum to "Prevention of food allergy - Early dietary interventions" [Allergol Int 65 (2016) 370-377]. ( 28081842 )
2017
41
Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy. ( 28802077 )
2017
42
Pollen food allergy syndrome in Turkey: Clinical characteristics and evaluation of its association with skin test reactivity to pollens. ( 28938837 )
2017
43
The Implications of DNA Methylation on Food Allergy. ( 28848217 )
2017
44
Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy. ( 29030101 )
2017
45
Genetic variation at the Th2 immune gene IL13 is associated with IgE-mediated paediatric food allergy. ( 28544327 )
2017
46
Genetically modified products and food allergy: Beliefs, evidence, and opportunity. ( 28890014 )
2017
47
Having your cake and EATing it too: early timing of multiple allergen introduction does not increase the risk of developing food allergy in standard risk, breastfed infants. ( 28053205 )
2017
48
Dietary intervention for preventing food allergy in children. ( 28914636 )
2017
49
Antibiotics and food allergy. ( 28070950 )
2017
50
Immunotherapy of Food Allergy: a Comprehensive Review. ( 28929421 )
2017
Sources

Variations for Food Allergy

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Expression for Food Allergy

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Search GEO for disease gene expression data for Food Allergy.
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Pathways for Food Allergy

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Pathways related to Food Allergy according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Cytokine Signaling in Immune system 66
Show member pathways
 13.2 IFNG IL10 IL13 IL4 IL5 STAT6
2
Pathways in cancer 37
12.71 IFNG IL13 IL4 IL5 STAT6
3
Allograft rejection 1 37
Show member pathways
 12.65 EPX FOXP3 IFNG IL10 IL13 IL4
4
Regulation of IFNA signaling 66
Show member pathways
 12.51 IFNG IL10 IL13 IL4 IL5 STAT6
5
NF-kappaB Signaling 4
12.46 FOXP3 IFNG IL10 IL4 STAT6
6
Immune response Fc epsilon RI pathway 22
Show member pathways
 12.44 IL13 IL4 IL5 MS4A2
7
T cell receptor signaling pathway 37
Show member pathways
 12.31 IFNG IL10 IL4 IL5
8
Th17 cell differentiation 37
Show member pathways
 12.29 FOXP3 IFNG IL10 IL13 IL4 IL5
9
IL-17 Family Signaling Pathways 65
Show member pathways
 12.22 IFNG IL13 IL4 IL5
10
Immune response IFN gamma signaling pathway 22
Show member pathways
 11.97 IFNG IL10 IL13 IL4 IL5
11
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.89 IFNG IL10 IL4 IL5
12
Interleukin-4 and 13 signaling 66
11.87 IL10 IL13 IL4 STAT6
13
IL12-mediated signaling events 1
Show member pathways
 11.83 IFNG IL4 STAT6
14
Glucocorticoid receptor regulatory network 1
11.71 IFNG IL13 IL4 IL5
15
Innate Lymphoid Cell Differentiation Pathways 65
11.67 IFNG IL10 IL13 IL4 IL5
16
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 1
Show member pathways
 11.66 FOXP3 IFNG IL4 IL5
17
IL4-mediated signaling events 1
11.56 IL10 IL4 IL5 STAT6
18
Lung fibrosis 1
11.55 IL13 IL4 IL5
19
Interleukin-10 signaling 66
11.43 IL10 IL13 IL4
20
Inflammatory Response Pathway 1
11.23 IFNG IL4 IL5
21
Development and heterogeneity of the ILC family 1
11.21 IFNG IL13 IL4 IL5
22
Cytokines and Inflammatory Response 1
11.03 IFNG IL10 IL13 IL4 IL5
23
Th2 Differentiation Pathway 65
10.83 FOXP3 IFNG IL10 IL13 IL4 IL5
24
OX40 Pathway 64
10.77 IFNG IL10 IL13 IL4 IL5
Sources

GO Terms for Food Allergy

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Cellular components related to Food Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ALB CETP CSN1S1 CSN3 EPX IFNG
2 extracellular space GO:0005615 9.36 ALB CETP CSN1S1 CSN3 EPX IFNG

Biological processes related to Food Allergy according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.88 IFNG IL10 IL13 IL4 IL5
2 positive regulation of interleukin-4 production GO:0032753 9.57 EPX FOXP3
3 high-density lipoprotein particle remodeling GO:0034375 9.56 ALB CETP
4 regulation of regulatory T cell differentiation GO:0045589 9.55 FOXP3 IFNG
5 positive regulation of macrophage activation GO:0043032 9.54 IL10 IL13
6 positive regulation of B cell proliferation GO:0030890 9.54 IL13 IL4 IL5
7 negative regulation of interleukin-10 production GO:0032693 9.52 EPX FOXP3
8 negative regulation of interleukin-17 production GO:0032700 9.51 FOXP3 IFNG
9 positive regulation of MHC class II biosynthetic process GO:0045348 9.49 IL10 IL4
10 type 2 immune response GO:0042092 9.46 IL10 IL4
11 negative regulation of interleukin-5 production GO:0032714 9.43 EPX FOXP3
12 regulation of isotype switching GO:0045191 9.4 IL10 IL4
13 cytokine-mediated signaling pathway GO:0019221 9.35 IL10 IL13 IL4 IL5 STAT6
14 negative regulation of endothelial cell apoptotic process GO:2000352 9.33 IL10 IL13 IL4
15 positive regulation of isotype switching to IgE isotypes GO:0048295 9.32 IL4 STAT6
16 negative regulation of complement-dependent cytotoxicity GO:1903660 9.26 IL13 IL4
17 immune response GO:0006955 9.1 IFNG IL10 IL13 IL4 IL5 MS4A2

Molecular functions related to Food Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IFNG IL10 IL13 IL4 IL5
Sources

Sources for Food Allergy

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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