MCID: FDL002
MIFTS: 52

Food Allergy

Categories: Blood diseases, Immune diseases, Respiratory diseases

Aliases & Classifications for Food Allergy

MalaCards integrated aliases for Food Allergy:

Name: Food Allergy 12 43 15 17 72
Food Hypersensitivity 12 44
Food Allergies 15 63
Allergy Food 55

Classifications:



External Ids:

Disease Ontology 12 DOID:3044
MeSH 44 D005512
SNOMED-CT 68 52332009
UMLS 72 C0016470

Summaries for Food Allergy

MedlinePlus : 43 Food allergy is an abnormal response to a food triggered by your body's immune system. In adults, the foods that most often trigger allergic reactions include fish, shellfish, peanuts, and tree nuts, such as walnuts. Problem foods for children can include eggs, milk, peanuts, tree nuts, soy, and wheat. The allergic reaction may be mild. In rare cases it can cause a severe reaction called anaphylaxis. Symptoms of food allergy include Itching or swelling in your mouth Vomiting, diarrhea, or abdominal cramps and pain Hives or eczema Tightening of the throat and trouble breathing Drop in blood pressure Your health care provider may use a detailed history, elimination diet, and skin and blood tests to diagnose a food allergy. When you have food allergies, you must be prepared to treat an accidental exposure. Wear a medical alert bracelet or necklace, and carry an auto-injector device containing epinephrine (adrenaline). You can only prevent the symptoms of food allergy by avoiding the food. After you and your health care provider have identified the foods to which you are sensitive, you must remove them from your diet.

MalaCards based summary : Food Allergy, also known as food hypersensitivity, is related to egg allergy and fruit allergy. An important gene associated with Food Allergy is IL4 (Interleukin 4), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Epinephrine and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related phenotypes are hematopoietic system and integument

Disease Ontology : 12 A hypersensitivity reaction type I disease that is an abnormal response to a food, triggered by the body's immune system.

PubMed Health : 63 About food allergies: If someone keeps having the same reaction (e.g. nausea, a rash or feeling unwell) after eating certain foods, it may be logical to assume that they have a food allergy. But food allergies are actually less common than many people believe: The symptoms are often caused by something else instead. It’s important to get the right diagnosis in order to get the right treatment – and avoid removing certain foods from your diet for no reason.

Wikipedia : 75 A food allergy is an abnormal immune response to food. The symptoms of the allergic reaction may range... more...

Related Diseases for Food Allergy

Diseases related to Food Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 406)
# Related Disease Score Top Affiliating Genes
1 egg allergy 33.2 IL5 IL4 IGHE
2 fruit allergy 33.0 SCP2 CETP
3 peanut allergy 32.4 IL13 IL10 IGHE IFNG FLG
4 urticaria 31.7 RNASE3 IGHE AOC1
5 nut allergy 31.7 STAT6 SCP2 IL5 FOXP3 FLG
6 exercise-induced anaphylaxis 31.6 IGHE FLG
7 milk allergy 31.5 RNASE3 IL5 IL4 IL10 CSN3 CSN1S1
8 cow milk allergy 31.2 RNASE3 IL5 IL10
9 cytokine deficiency 31.2 IL5 IL13
10 gastroenteritis 31.2 RNASE3 IL5 IL4 IL10
11 eosinophilic gastroenteritis 31.1 RNASE3 IL5 EPX
12 dermatitis 31.1 IL5 IL4 IL13 IGHE IFNG FLG
13 otitis media 31.0 RNASE3 IL4 IL10 IGHE
14 rhinitis 30.8 RNASE3 IL5 IL4 IL13 IGHE EPX
15 immune deficiency disease 30.8 IL4 IL13 IL10
16 allergic asthma 30.6 STAT6 RNASE3 IL5 IL4 IL13 IL10
17 angioimmunoblastic lymphadenopathy with dysproteinemia 30.6 IL5 IL13
18 pollen allergy 30.6 RNASE3 IL5 IL13 FOXP3 EPX
19 colitis 30.5 IL4 IL10 IFNG FOXP3
20 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 30.5 IL10 IFNG FOXP3
21 intrinsic asthma 30.5 RNASE3 IL5 IL4
22 gastrointestinal system disease 30.5 IL10 IFNG FOXP3
23 eosinophilic granuloma 30.4 RNASE3 EPX
24 hypereosinophilic syndrome 30.4 RNASE3 IL5 IL4 IL13 IGHE EPX
25 hyper ige syndrome 30.4 IL4 IGHE IFNG
26 multiple sclerosis 30.3 IL4 IL10 IFNG FOXP3
27 contact dermatitis 30.3 IL5 IL4 IL10 IFNG FLG
28 autoimmune disease 30.2 IL4 IL10 IFNG FOXP3
29 autoimmune enteropathy 30.2 FOXP3 CSN1S1
30 pulmonary tuberculosis 30.1 IL4 IL10 IFNG
31 latex allergy 30.1 RNASE3 IL5 IL4 IL13 IGHE FLG
32 ige responsiveness, atopic 30.1 STAT6 RNASE3 IL5 IL4 IL13 IL10
33 dermatitis, atopic 30.1 STAT6 RNASE3 IL5 IL4 IL13 IL10
34 respiratory allergy 30.1 STAT6 RNASE3 IL5 IL4 IL13 IL10
35 lung disease 30.0 RNASE3 IL5 IL13 IL10
36 rheumatic disease 30.0 IL10 IFNG FLG
37 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 29.9 IL4 IL10 IFNG FOXP3
38 allergic conjunctivitis 29.9 RNASE3 IL5 IL4 IL13 IFNG
39 orofacial granulomatosis 29.9 IL4 IL10 IFNG FLG
40 inflammatory bowel disease 29.8 STAT6 IL4 IL13 IL10 IFNG FOXP3
41 peach allergy 29.8 SCP2 PVALB IGHE
42 conjunctivitis 29.8 RNASE3 IL5 IL4 IL13 IFNG EPX
43 tetanus 29.8 IL5 IL4 IL13 IL10 IFNG
44 allergic rhinitis 29.8 RNASE3 IL5 IL4 IL13 IL10 IGHE
45 skin disease 29.7 RNASE3 IL5 IL4 IL13 IL10 IFNG
46 rheumatoid arthritis 29.6 IL4 IL10 IFNG FOXP3 FLG
47 apple allergy 29.5 SCP2 IL5 IL4 IL13 IL10 FOXP3
48 proteasome-associated autoinflammatory syndrome 1 29.3 RNASE3 IL5 IL4 IL13 IL10 IGHE
49 asthma 28.7 STAT6 RNASE3 IL5 IL4 IL13 IL10
50 allergic hypersensitivity disease 28.6 SCP2 RNASE3 IL5 IL4 IL13 IL10

Graphical network of the top 20 diseases related to Food Allergy:



Diseases related to Food Allergy

Symptoms & Phenotypes for Food Allergy

MGI Mouse Phenotypes related to Food Allergy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.92 EPX FOXP3 IFNG IL10 IL13 IL4
2 integument MP:0010771 9.8 CSN3 FOXP3 IFNG IL10 IL13 IL4
3 liver/biliary system MP:0005370 9.7 FOXP3 IFNG IL10 IL4 IL5 SCP2
4 respiratory system MP:0005388 9.5 FOXP3 IFNG IL10 IL13 IL4 IL5
5 vision/eye MP:0005391 9.17 AOC1 FOXP3 IFNG IL10 IL4 PVALB

Drugs & Therapeutics for Food Allergy

PubMed Health treatment related to Food Allergy: 63

The main thing people can do to prevent allergic reactions is avoid the food that causes them. Medication is generally only used in acute situations, if people have a more severe allergic reaction. It doesn’t tend to be used for the long-term treatment of food allergies. Anaphylactic reactions are treated using emergency kits. These contain medications to reduce severe allergic reactions and prevent them from getting worse.

Drugs for Food Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 219)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
2
Racepinephrine Approved Phase 4 329-65-7 838
3
Montelukast Approved Phase 4 158966-92-8 5281040
4
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
5
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
6
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
7
Omalizumab Approved, Investigational Phase 4 242138-07-4
8
BCG vaccine Investigational Phase 4
9 Mesalamine Phase 4 89-57-6
10 Anti-Inflammatory Agents, Non-Steroidal Phase 4
11 Antirheumatic Agents Phase 4
12 Calcium Supplement Phase 4
13 Sympathomimetics Phase 4
14 Adrenergic Agonists Phase 4
15 Adrenergic alpha-Agonists Phase 4
16 Adrenergic beta-Agonists Phase 4
17 Mydriatics Phase 4
18 Adrenergic Agents Phase 4
19 Epinephryl borate Phase 4
20 Vasoconstrictor Agents Phase 4
21 Hormones Phase 4
22 Bifidobacterium Phase 4
23 Cytochrome P-450 Enzyme Inducers Phase 4
24 Hormone Antagonists Phase 4
25 Leukotriene Antagonists Phase 4
26 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
27 Antacids Phase 4
28 diuretics Phase 4
29 Natriuretic Agents Phase 4
30 Anti-Ulcer Agents Phase 4
31 Vaccines Phase 4
32 Adjuvants, Immunologic Phase 4
33 Corticotropin-Releasing Hormone Phase 4
34 Adrenocorticotropic Hormone Phase 4
35 Melanocyte-Stimulating Hormones Phase 4
36 beta-endorphin Phase 4
37 Anti-Allergic Agents Phase 4
38 Respiratory System Agents Phase 4
39 Anti-Asthmatic Agents Phase 4
40 Pharmaceutical Solutions Phase 4
41
Zinc Approved, Investigational Phase 3 7440-66-6 32051
42
Glutamic acid Approved, Nutraceutical Phase 3 56-86-0 33032
43
Vitamin D3 Approved, Nutraceutical Phase 3 67-97-0 6221 5280795
44
Ergocalciferol Approved, Nutraceutical Phase 3 50-14-6 5280793
45
Vitamin D Approved, Nutraceutical, Vet_approved Phase 3 1406-16-2
46 Vitamins Phase 3
47 Vitamin D2 Phase 3
48 Ergocalciferols Phase 3
49 Calciferol Phase 3
50 Bone Density Conservation Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 359)
# Name Status NCT ID Phase Drugs
1 CLINICAL MANAGEMENT OF CHILDHOOD INTESTINAL LYMPHOID NODULAR HYPERPLASIA: A RANDOMIZED CONTROLLED CLINICAL TRIAL. Unknown status NCT01789294 Phase 4 Mesalamine
2 A Double Blind Placebo Controlled Randomised Trial to Study the Effects of Birch Pollen Specific Immunotherapy (BP-SIT) on the Symptoms of the Oral Allergy Syndrome in Adult Patients Unknown status NCT01431859 Phase 4
3 Phase 4 Study of Effects of Montelukast Treatment on Allergic Inflammation in Children With and Without Food Allergy, Single Centered, Randomised, Double Blind, Placebo Controlled Parallel Group Cross-over Study Completed NCT01618929 Phase 4 Montelukast
4 Integrated Approaches to Food Allergen and Allergy Risk Management: iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions Completed NCT02552537 Phase 4 Omeprazole;Placebo
5 A Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy of Montelukast (Singulair) in Participants Ages 1 - 8 Years Diagnosed With Atopic Dermatitis Induced by Food Allergens Completed NCT00557284 Phase 4 Montelukast;Placebo
6 Pharmacokinetics of Intramuscular Adrenaline in Food--Allergic Teenagers: Does Dose Matter? Completed NCT03366298 Phase 4
7 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. A Prospective, Randomised, Clinical Trial. Completed NCT01694108 Phase 4
8 A Phase-IV, Open-label Study to Evaluate Safety/Tolerability of Once-daily AVAMYS (TM) Aqueous Nasal Spray 110mcg Among Vietnamese Adult Patients With Established Perennial Allergic Rhinitis (PAR) Completed NCT01270958 Phase 4 Avamys aqueous nasal spray 110mcg
9 Effects of an Association of the Two Bifidobacteria Probiotics Bifidobacterium Breve B632 and Bifidobacterium Breve BR03 in Intestinal Bacterial Colonization and in the Prevention and/or Reduction of the Incidence of Colics in Infants Completed NCT03219931 Phase 4 Bifidobacterium breve BR03 and Bifidobacterium breve B632;Placebos
10 The Effect of Corticotrophin-releasing Hormone (CRH) on Esophageal Motility in Healthy Volunteers Completed NCT02736734 Phase 4 CRH
11 Can Vitamin D Supplementation in Infants Prevent Food Allergy in the First Year of Life? The VITALITY Trial. Recruiting NCT02112734 Phase 4 Vitamin D;placebo
12 Basophil Activation Test (BAT) Sensitivity in Child Food Allergy Recruiting NCT01966640 Phase 4
13 Protection From Food Induced Anaphylaxis by Reducing the Serum Level of Specific IgE (Protana). Recruiting NCT03964051 Phase 4 Omalizumab Injection
14 Treatment With Omalizumab in Food Allergic Children (TOFAC) Not yet recruiting NCT04037176 Phase 4 Omalizumab
15 Use of Probiotic Bacteria in Prevention of Allergic Disease in Children 1999-2008 Unknown status NCT00298337 Phase 2, Phase 3 Mixture of probiotic bacteria and prebiotic oligosaccharide
16 Parmigiano-Reggiano Cheese as a Possible Strategy of Immunonutrition Able to Stimulate the Acquisition of Oral Tolerance in Childre With Cow's Milk Allergy Unknown status NCT02081651 Phase 3
17 Effects of GOS/PDX Supplemented Formula in Preventing and Modifying the History of Allergy and Acute Infections in a Population of Infants at Risk of Atopy Completed NCT02116452 Phase 3
18 Development and Field Testing of Ready-to-use-therapeutic Foods Made of Local Ingredients in Bangladesh for the Treatment of Children With Severe Acute Malnutrition Completed NCT01889329 Phase 2, Phase 3
19 Efficacy of a New Hypotonic Oral Rehydration Solution Containing Zinc and Prebiotics in the Treatment of Children With Acute Diarrhea Completed NCT01025583 Phase 2, Phase 3
20 Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen Oral Immunotherapy (OIT) in Food Allergic Children and Adults (CoFAR-11) Recruiting NCT03881696 Phase 3 Omalizumab;Placebo for Omalizumab;Multi-Allergen Oral Immunotherapy;Placebo for Multi-Allergen Oral Immunotherapy
21 THE PEBBLES STUDY: A Randomised Controlled Trial to Prevent Eczema, Food Allergy and Sensitisation Using a Skin Barrier Improvement Strategy Recruiting NCT03667651 Phase 3 EpiCeram
22 Phase III Study of Metabolic Intervention With Glutamate in Coronary Surgery II Recruiting NCT02592824 Phase 3 glutamate infusion;saline infusion
23 Open-label Follow-up Study of the PEPITES Study to Evaluate the Long-term Efficacy and Safety of Viaskin Peanut Active, not recruiting NCT03013517 Phase 3 Viaskin Peanut 250µg
24 Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood Asthma (VDAART) Active, not recruiting NCT00920621 Phase 3
25 Real-World AR101 Market-Supporting Experience Study in Peanut-Allergic Children, Active Treatment Arm Open-Label Extension Study (RAMSES OLE) Active, not recruiting NCT03337542 Phase 3
26 A Randomised, Controlled Trial to Determine if BCG Immunisation at Birth Reduces Allergy and Infection in Infants Active, not recruiting NCT01906853 Phase 3
27 EFFICACITE ET INNOCUITE DU TANNATE DE GELATINE DANS LE TRAITEMENT DE LA DIARRHEE AIGUË DE L'ENFANT. UNE ETUDE RANDOMISEE, CONTROLEE, EN DOUBLE AVEUGLE (INDIGO) Not yet recruiting NCT04065529 Phase 3
28 Investigation of the Efficacy of the Food Allergy Herbal Formula (FAHF-2TM) in Patients With Food Allergy - Phase II Trial Unknown status NCT00602160 Phase 2 FAHF-2 (TM)
29 The Effect of Extrinsic Factors on Food Allergy Unknown status NCT01429896 Phase 2
30 Clinical Desensitization and Tolerance Following Peanut Oral Immunotherapy and Subsequent Allergen Avoidance Unknown status NCT01750879 Phase 1, Phase 2 Peanut Flour;Oat Flour
31 Effectiveness and Efficacy of Zinc With Probiotics for the Treatment of Acute Diarrhea in Young Children Unknown status NCT01140074 Phase 2 Zinc Sulfate
32 Randomized, Controlled, Blinded, Pilot Study Using Xolair in Rush Multi Oral Immunotherapy in Multi Food Allergic Patients Completed NCT02643862 Phase 1, Phase 2 Xolair;Placebo
33 Oral Desensitization to Egg With Subsequent Induction of Sustained Unresponsiveness for Egg-Allergic Children Using Baked Egg or Egg Oral Immunotherapy (OIT) Completed NCT01846208 Phase 2 Egg Oral Immunotherapy;Baked Egg
34 Epicutaneous Immunotherapy (EPIT) for Peanut Allergy: A Randomized, Double-Blind, Placebo-Controlled, Phase II Study in Children and Adults (DAIT COFAR6) Completed NCT01904604 Phase 2
35 A Phase 2 Study Multi Oral Immunotherapy in Multi Food Allergic Patients to Test Tolerance M-TAX Study Completed NCT02626611 Phase 2 Omalizumab;Food Flour Buildup
36 Sublingual Immunotherapy for Peanut Allergy: A Randomized, Double-Blind, Placebo-Controlled, Phase I/II Pilot Study With a Whole Peanut Extract Completed NCT00580606 Phase 1, Phase 2 Glycerinated peanut allergenic extract;Placebo for peanut extract (glycerin)
37 Inhibition of Anaphylaxis by Ibrutinib Completed NCT03149315 Phase 2 Ibrutinib
38 Oral Desensitization to Egg With Subsequent Induction of Tolerance for Egg-Allergic Children (CoFAR 3) Completed NCT00461097 Phase 2 Egg oral immunotherapy;Control Group
39 Effects of Omalizumab on Peanut Allergen Induced Cellular and Clinical Responses in Peanut Allergic Adults Completed NCT00949078 Phase 2 omalizumab
40 Oral Immunotherapy for Wheat Allergy Completed NCT01980992 Phase 1, Phase 2 Wheat OIT
41 Pilot Study of Omalizumab in Eosinophilic Gastroenteritis Completed NCT00084097 Phase 2 Omalizumab
42 Dietary Intervention in Milk Allergy and Tolerance Development Completed NCT00778258 Phase 2
43 FAST-Fish -Food Allergy Specific Treatment for Fish Allergy. Completed NCT02017626 Phase 1, Phase 2
44 A Double-blinded, Placebo-controlled Study of Peanut Sublingual Immunotherapy in Children - DBPC Peanut SLIT Completed NCT00597727 Phase 2 Peanut SLIT;Placebo SLIT
45 Mechanisms of Desensitization During Peanut Oral Immunotherapy Completed NCT01814241 Phase 2 Open label peanut OIT
46 A Multinational Phase IIb Study to Investigate the Efficacy and Safety of Subcutaneous Immunotherapy With a Modified Fish- Parvalbumin Given in Single Rising and Maintenance Doses to Subjects Allergic to Fish Completed NCT02382718 Phase 2
47 Oral Immunotherapy for Peanut Allergy (2nd Generation PMIT Collaboration With Arkansas Children's) Completed NCT00597675 Phase 2
48 Determining the Efficacy and Value of Immunotherapy on the Likelihood of Peanut Tolerance: The DEVIL Study; Grant "Optimizing Tolerance Induction in Peanut Allergy: The DEVIL Study" Completed NCT00932828 Phase 2 Peanut oral immunotherapy
49 A Phase II Multicenter, Controlled, Double-Blind Study Using Immunoprophylaxis in the Primary Prevention of Allergic Disease (ITN025AD) Completed NCT00346398 Phase 2
50 Efficacy of Baked Milk in Accelerating Resolution of Cow's Milk Allergy Completed NCT02738060 Phase 2

Search NIH Clinical Center for Food Allergy

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Cromolyn
Cromolyn Sodium

Cochrane evidence based reviews: food hypersensitivity

Genetic Tests for Food Allergy

Anatomical Context for Food Allergy

MalaCards organs/tissues related to Food Allergy:

41
Testes, Skin, T Cells, Breast, Liver, B Cells, Colon

Publications for Food Allergy

Articles related to Food Allergy:

(show top 50) (show all 8360)
# Title Authors PMID Year
1
Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety. 17
31030987 2019
2
Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy: The PEPITES Randomized Clinical Trial. 17
30794314 2019
3
Quick Uptakes: Food Allergies: Not Just Kid Stuff. 17
30840029 2019
4
[Component-based diagnostic approach. Detection of sensitization to lipid transfer proteins in food allergy]. 9 38
20390241 2010
5
Anaphylaxis to wheat flour-derived foodstuffs and the lipid transfer protein syndrome: a potential role of wheat lipid transfer protein Tri a 14. 9 38
20016200 2010
6
Food allergy after liver transplantation in children: a prospective study. 9 38
19239659 2009
7
Usefulness of wheat and soybean specific IgE antibody titers for the diagnosis of food allergy. 9 38
19776678 2009
8
Food allergy among children in the United States. 9 38
19917585 2009
9
Component-resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan-allergens. 9 38
19877313 2009
10
Is serum total IgE levels a good predictor of allergies in children? 9 38
19813686 2009
11
The non-specific lipid transfer protein, Ara h 9, is an important allergen in peanut. 9 38
19624524 2009
12
Maize food allergy: lipid-transfer proteins, endochitinases, and alpha-zein precursor are relevant maize allergens in double-blind placebo-controlled maize-challenge-positive patients. 9 38
19669736 2009
13
Management of cow's milk protein allergy in infants and young children: an expert panel perspective. 9 38
19702611 2009
14
The role of immunoglobulin E-binding epitopes in the characterization of food allergy. 9 38
19568005 2009
15
Elevation of plasma eotaxin levels in children with food allergy. 9 38
19564714 2009
16
Detection of IgE, IgG, IgA and IgM antibodies against raw and processed food antigens. 9 38
19435515 2009
17
EpidemAAITO: features of food allergy in Italian adults attending allergy clinics: a multi-centre study. 9 38
19220321 2009
18
Cytokine profile in children with asthma undergoing food challenges. 9 38
19274928 2009
19
Food allergy in Alergológica-2005. 9 38
19530417 2009
20
Is caesarean delivery associated with sensitization to food allergens and IgE-mediated food allergy: a systematic review. 9 38
19076564 2008
21
Association factors for atopic dermatitis in nursery school children in Ishigaki islands - Kyushu University Ishigaki Atopic Dermatitis Study (KIDS). 9 38
18693163 2008
22
Helicobacter pylori as a protective factor against food allergy. 9 38
18758415 2008
23
The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy. 9 38
18502490 2008
24
The role of protein digestibility and antacids on food allergy outcomes. 9 38
18539189 2008
25
Asthma and food allergy. 9 38
18043270 2008
26
Lupin sensitization and clinical allergy in food allergic children in Norway. 9 38
18076722 2008
27
Confirmation of the association between high levels of immunoglobulin E food sensitization and eczema in infancy: an international study. 9 38
18028467 2008
28
The predictive value of specific immunoglobulin E levels for the first diagnosis of cow's milk allergy. A critical analysis of pediatric literature. 9 38
17651374 2007
29
Uveitis associated with immunoglobulin E-mediated allergic diseases. 9 38
17894692 2007
30
Hypogammaglobulinaemia secondary to cow-milk allergy in children under 2 years of age. 9 38
17498216 2007
31
Lipid transfer protein allergy: primary food allergy or pollen/food syndrome in some cases. 9 38
17489047 2007
32
Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the FOXP3 gene. 9 38
17484868 2007
33
Influence of the allelic variants encoded at the Gli-B1 locus, responsible for a major allergen of wheat, on IgE reactivity for patients suffering from food allergy to wheat. 9 38
17263477 2007
34
Thioredoxin and food allergy. 9 38
17141854 2007
35
[Contribution of indicators of sensitized T lymphocytes in the diagnosis of IgE independent and IgE dependent cow's allergy in children]. 9 38
17965461 2007
36
Rice: another potential cause of food allergy in patients sensitized to lipid transfer protein. 9 38
17192718 2007
37
Wheat IgE-mediated food allergy in European patients: alpha-amylase inhibitors, lipid transfer proteins and low-molecular-weight glutenins. Allergenic molecules recognized by double-blind, placebo-controlled food challenge. 9 38
17496422 2007
38
Food allergy to proteins. 9 38
17245088 2007
39
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects. 9 38
16815152 2006
40
Prevalence of elevated total IgE and food allergies in a consecutive series of ENT pediatric patients. 9 38
16564375 2006
41
Eosinophilic esophagitis. 9 38
16606552 2006
42
Measurements of eosinophil activation before and after food challenges in adults with food hypersensitivity. 9 38
16757922 2006
43
Sensitivity and specificity of food specific IgE and IgG determinations for the diagnosis of food allergy. 9 38
16673562 2006
44
[Eosinophil cationic protein as a marker of eosinophil activity]. 9 38
17203813 2006
45
Time course of total and food specific IgE antibodies (Rast Fx5) in the developing allergic child. 9 38
16285230 2005
46
Utility of the ratio of food-specific IgE/total IgE in predicting symptomatic food allergy in children. 9 38
15969684 2005
47
Controlled oral food challenges in children--when indicated, when superfluous? 9 38
15932374 2005
48
Epsilon germ-line and IL-4 transcripts are expressed in human intestinal mucosa and enhanced in patients with food allergy. 9 38
15876314 2005
49
Food allergen sensitization in inner-city children with asthma. 9 38
15867869 2005
50
Peanut- and cow's milk-specific IgE, Th2 cells and local anaphylactic reaction are induced in Balb/c mice orally sensitized with cholera toxin. 9 38
15813812 2005

Variations for Food Allergy

Expression for Food Allergy

Search GEO for disease gene expression data for Food Allergy.

Pathways for Food Allergy

Pathways related to Food Allergy according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.92 STAT6 RNASE3 IL5 IL4 IL13 IL10
2
Show member pathways
13.25 STAT6 IL5 IL4 IL13 IL10 IGHE
3
Show member pathways
12.75 RNASE3 IL5 IL4 IL13 IL10 IFNG
4 12.74 STAT6 IL5 IL4 IL13 IFNG
5
Show member pathways
12.47 IL5 IL4 IL13 IGHE
6 12.47 STAT6 IL4 IL10 IFNG FOXP3
7
Show member pathways
12.46 IL5 IL4 IL10 IFNG
8
Show member pathways
12.4 STAT6 IL5 IL4 IL13 IL10 IFNG
9
Show member pathways
12.32 STAT6 IL5 IL4 IL13 IL10 IFNG
10
Show member pathways
12.24 IL5 IL4 IL13 IFNG
11
Show member pathways
12.17 IL5 IL4 IL13 IL10 IFNG
12
Show member pathways
11.99 IL5 IL4 IL13 IL10 IFNG
13
Show member pathways
11.92 IL4 IL13 IFNG
14 11.91 STAT6 IL4 IL13 IL10 IGHE
15 11.9 IL5 IL4 IL10 IFNG
16
Show member pathways
11.86 STAT6 IL4 IFNG
17 11.76 STAT6 IL10 IFNG
18 11.74 IL5 IL4 IL13 IFNG
19
Show member pathways
11.69 IL5 IL4 IFNG FOXP3
20 11.67 IL5 IL4 IL13 IL10 IFNG
21 11.65 IL4 IL13 IL10 IFNG
22 11.58 IL5 IL4 IL13
23 11.45 IL4 IL13 IL10
24 11.45 STAT6 IL5 IL4 IL10 IGHE
25 11.24 IL5 IL4 IFNG
26 11.24 IL5 IL4 IL13 IFNG
27 11.12 IL5 IL4 IL13 IL10
28 11.02 IL5 IL4 IL13 IL10 IFNG
29 10.83 STAT6 IL5 IL4 IL13 IL10 IFNG
30 10.77 IL5 IL4 IL13 IL10 IFNG

GO Terms for Food Allergy

Cellular components related to Food Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 RNASE3 IL5 IL4 IL13 IL10 IFNG
2 extracellular region GO:0005576 9.4 RNASE3 IL5 IL4 IL13 IL10 IGHE

Biological processes related to Food Allergy according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.81 RNASE3 IL10 IGHE EPX
2 positive regulation of cold-induced thermogenesis GO:0120162 9.71 STAT6 IL4 IL13
3 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.67 IL4 IL13 IFNG
4 positive regulation of interleukin-4 production GO:0032753 9.58 FOXP3 EPX
5 positive regulation of macrophage activation GO:0043032 9.57 IL13 IL10
6 regulation of regulatory T cell differentiation GO:0045589 9.56 IFNG FOXP3
7 negative regulation of interleukin-10 production GO:0032693 9.55 FOXP3 EPX
8 positive regulation of B cell proliferation GO:0030890 9.54 IL5 IL4 IL13
9 negative regulation of interleukin-17 production GO:0032700 9.52 IFNG FOXP3
10 positive regulation of MHC class II biosynthetic process GO:0045348 9.48 IL4 IL10
11 negative regulation of interleukin-5 production GO:0032714 9.46 FOXP3 EPX
12 type 2 immune response GO:0042092 9.43 IL4 IL10
13 immune response GO:0006955 9.43 IL5 IL4 IL13 IL10 IGHE IFNG
14 regulation of isotype switching GO:0045191 9.4 IL4 IL10
15 negative regulation of endothelial cell apoptotic process GO:2000352 9.33 IL4 IL13 IL10
16 positive regulation of isotype switching to IgE isotypes GO:0048295 9.32 STAT6 IL4
17 negative regulation of complement-dependent cytotoxicity GO:1903660 9.26 IL4 IL13
18 cytokine-mediated signaling pathway GO:0019221 9.1 STAT6 IL5 IL4 IL13 IL10 IGHE

Molecular functions related to Food Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL5 IL4 IL13 IL10 IFNG

Sources for Food Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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