MCID: FRM001
MIFTS: 17

Freemartinism

Categories: Endocrine diseases

Aliases & Classifications for Freemartinism

MalaCards integrated aliases for Freemartinism:

Name: Freemartinism 12 44 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4671
MeSH 44 D005611
UMLS 70 C0016697

Summaries for Freemartinism

MalaCards based summary : Freemartinism is related to disorder of sexual development and infertility. An important gene associated with Freemartinism is AMELX (Amelogenin X-Linked). Affiliated tissues include testis.

Related Diseases for Freemartinism

Graphical network of the top 20 diseases related to Freemartinism:



Diseases related to Freemartinism

Symptoms & Phenotypes for Freemartinism

Drugs & Therapeutics for Freemartinism

Search Clinical Trials , NIH Clinical Center for Freemartinism

Cochrane evidence based reviews: freemartinism

Genetic Tests for Freemartinism

Anatomical Context for Freemartinism

MalaCards organs/tissues related to Freemartinism:

40
Testis

Publications for Freemartinism

Articles related to Freemartinism:

(showing 69, show less)
# Title Authors PMID Year
1
Economics of Twin Pregnancies in Dairy Cattle. 61
33672462 2021
2
A rare case of heteropaternal twin calves after natural mating in Brazil. 61
33791026 2021
3
Managing embryonic and calves losses after twin pregnancies induced by transfer of in vitro-produced Nellore embryos. 61
32345381 2020
4
Application of droplet digital PCR in diagnosing of X monosomy in mares. 61
31793061 2020
5
Genetic disorders of sex development in cats: An update. 61
32414464 2020
6
Technical note: Droplet digital PCR as a new molecular method for a simple and reliable diagnosis of freemartinism in cattle. 61
31447157 2019
7
Early Diagnostics of Freemartinism in Polish Holstein-Friesian Female Calves. 61
31739521 2019
8
Low prevalence of male microchimerism in women with Mayer-Rokitansky-Küster-Hauser syndrome. 61
31111890 2019
9
Disorders of Sex Development Are an Emerging Problem in French Bulldogs: A Description of Six New Cases and a Review of the Literature. 61
32203972 2019
10
Freemartinism in replacement ewe-lambs of the Ripollesa sheep breed. 61
30304885 2018
11
Applying real-time quantitative PCR to diagnosis of freemartin in Holstein cattle by quantifying SRY gene: a comparison experiment. 61
29719732 2018
12
Facets of Clinical Appearance and Aetiology in an Unusual Bovine Amorphus Globosus. 61
28718952 2017
13
Dizygotic monochorionic canine fetuses with blood chimaerism and suspected freemartinism. 61
26304144 2017
14
Natural exceptions to normal gonad development in mammals. 61
22626995 2013
15
Abnormal position of lymph nodes in a freemartin sheep. 61
30155428 2012
16
Freemartinism and FecXR allele determination in replacement ewes of the Rasa Aragonesa sheep breed by duplex PCR. 61
19773062 2009
17
XX/XY chimerism in cattle: clinical and cytogenetic studies. 61
18418032 2008
18
Diagnosis of bovine freemartinism by fluorescence in situ hybridization on interphase nuclei using a bovine Y chromosome-specific DNA probe. 61
17870153 2007
19
Comparison of cytogenetics and polymerase chain reaction based detection of the amelogenin gene polymorphism for the diagnosis of freemartinism in cattle. 61
17037616 2006
20
A case of freemartin with atresia recti and ani in Japanese Black calf. 61
15581503 2005
21
Freemartinism in river buffalo: clinical and cytogenetic observations. 61
15627757 2005
22
Genetic aspects of twinning in cattle. 61
12084971 2002
23
Inter-relationships among gonadotrophins, reproductive steroids and inhibin in freemartin ewes. 61
11597305 2001
24
Births of freemartins derived from embryos reconstructed with ear fibroblasts. 61
11411508 2001
25
XX/XY chimerism and freemartinism in a female llama co-twin to a male. 61
10530330 1999
26
The diagnosis of freemartinism in cattle using sex-specific DNA sequences. 61
10425251 1999
27
[Comparison of different methods for the diagnosis of freemartinism--blood group serology, cytology and polymerase chain reaction]. 61
8591746 1995
28
Freemartinism among singleton bovine females born from multiple embryo transfer. 61
16727729 1995
29
Development of the gubernaculum and processus vaginalis in freemartinism: further evidence in support of a specific fetal testis hormone governing male-specific gubernacular development. 61
7710137 1995
30
Diagnosis of freemartinism in cattle: the need for clinical and cytogenic evaluation. 61
8050953 1994
31
Retrospective studies on the measurements, karyotyping and pathology of reproductive organs of bovine freemartins. 61
8040370 1994
32
A fast and highly sensitive method for detecting freemartinism in bovine twins using immunomagnetic beads and Y-specific PCR primers. 61
8239077 1993
33
Infertility due to abnormalities of the ovaries in cattle. 61
8348373 1993
34
Effects of testosterone propionate upon the sexual and aggressive behavior of adult male marmosets (Callithrix jacchus) castrated as neonates. 61
8349280 1993
35
[Genome diagnosis in domestic animals]. 61
7987275 1993
36
Andrological study of an intersex ram. 61
1443677 1992
37
Freemartinism in a captive herd of Rocky Mountain bighorn sheep (Ovis canadensis). 61
1512891 1992
38
Diagnosis of bovine freemartinism by the polymerase chain reaction method. 61
1362861 1992
39
Congenital malformations in twins in England and Wales. 61
2045744 1991
40
[Intersexuality in domestic mammals]. 61
2206293 1990
41
Freemartinism in red deer (Cervus elaphus L.). 61
2249475 1990
42
Diagnosis of freemartinism in sheep. 61
2916299 1989
43
Anti-müllerian hormone and freemartinism: inhibition of germ cell development and induction of seminiferous cord-like structures in rat fetal ovaries exposed in vitro to purified bovine AMH. 61
3244905 1988
44
Monoclonal antibodies raised against bovine anti-müllerian hormone: bovine, ovine, and caprine hormones share a set of identical epitopes. 61
2435327 1986
45
Sex chromatin as a useful tool for detection of freemartinism in bovine twins. 61
3995247 1985
46
[Genetic research in the field of reproductive pathology and genetic prophylaxis in agricultural animals in the Socialist Republic of Romania]. 61
6683694 1983
47
Clinical analysis of reproductive failure among female buffaloes (Bubalus bubalis) under village management in Andhra Pradesh. 61
16725762 1982
48
Artificial induction of twinning in cattle by means of supplemental embryo transfer. 61
16725660 1981
49
Significance of atrophic ovaries in livestock production in northern Nigeria. 61
7196640 1981
50
Probable freemartinism in a goat. 61
7193198 1980
51
Growth and reproductive development in freemartins hormonally treated from 1 to 79 weeks of age. 61
573192 1979
52
Heifer sterility and freemartinism. 61
560082 1977
53
A study of bovine freemartinism-morphological variations of the genitalia and sex-chromosome chimerism. 61
873602 1977
54
Heifer sterility associated with single-birth freemartinism. 61
867757 1977
55
[The first manifestations of freemartinism in the calf fetus do not depend on XX/XY chromosomal chimerism]. 61
820441 1976
56
[Case of male pseudohermaphroditism in cattle. (Bos taurus L.) with a 60 XY karyotype]. 61
1181556 1975
57
[Twin gestation, chimerism and freemartinism in the horse]. 61
4857995 1974
58
[Cause and occurrence of freemartinism in domestic animals]. 61
4580762 1973
59
[Causes and occurrence of freemartinism in domestic animals]. 61
4585452 1973
60
[Chimerism and freemartinism in a bovine sextuplet]. 61
4782015 1973
61
[Absence of correlation between XX-XY chimerism in the liver and the first signs of freemartinism in the calf fetus]. 61
5024690 1972
62
The incidence of freemartinism in sheep. 61
5099639 1971
63
Some aspects of twin-gestation in the mare. 61
4248640 1970
64
Blood cell chimerism and freemartinism in heterosexual bovine quadruplets. 61
5480932 1970
65
The leukocyte culture method in the diagnosis of freemartinism. 61
4234791 1968
66
XX-XY chimerism in a bovine true hermaphrodite: an insight into the understanding of freemartinism. 61
5702324 1968
67
[Freemartinism]. 61
5324967 1965
68
Attempts to induce bovine freemartinism experimentally. 61
5891100 1965
69
[Conditions of intrauterine development of Bos taurus causing phenomenon of freemartinism]. 61
13083506 1953

Variations for Freemartinism

Expression for Freemartinism

Search GEO for disease gene expression data for Freemartinism.

Pathways for Freemartinism

GO Terms for Freemartinism

Sources for Freemartinism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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