MCID: FRN003
MIFTS: 30

Frontal Convexity Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Frontal Convexity Meningioma

MalaCards integrated aliases for Frontal Convexity Meningioma:

Name: Frontal Convexity Meningioma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:8000
NCIt 50 C5292
UMLS 70 C1333643

Summaries for Frontal Convexity Meningioma

MalaCards based summary : Frontal Convexity Meningioma is related to secretory meningioma and meningioma, familial, and has symptoms including seizures and headache. An important gene associated with Frontal Convexity Meningioma is AGGF1 (Angiogenic Factor With G-Patch And FHA Domains 1), and among its related pathways/superpathways are HIV Life Cycle and Downstream signaling events of B Cell Receptor (BCR). Affiliated tissues include cortex, tongue and pituitary, and related phenotypes are Decreased cell migration and Decreased cell migration

Related Diseases for Frontal Convexity Meningioma

Diseases related to Frontal Convexity Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 secretory meningioma 30.3 TRAF7 NF2 KLF4
2 meningioma, familial 28.7 TRAF7 TERT PIK3CA PDGFRB NF2 KLF4
3 extraventricular neurocytoma 10.3 IDH1 GFAP
4 pediatric meningioma 10.3 TRAF7 NF2
5 intraventricular meningioma 10.3 TRAF7 NF2
6 olfactory groove meningioma 10.3 TRAF7 NF2
7 psammomatous meningioma 10.3 TRAF7 NF2
8 meninges hemangiopericytoma 10.3 TRAF7 NF2
9 anterior cranial fossa meningioma 10.3 TRAF7 NF2
10 cerebral convexity meningioma 10.3 NF2 IDH1
11 suprasellar meningioma 10.3 NF2 GFAP
12 brain meningioma 10.3 TRAF7 NF2
13 angiocentric glioma 10.3 IDH1 GFAP
14 intraneural perineurioma 10.3 TRAF7 NF2
15 spinal cord oligodendroglioma 10.3 IDH1 GFAP
16 papillary ependymoma 10.3 NF2 GFAP
17 transitional meningioma 10.3 TRAF7 NF2
18 meningothelial meningioma 10.3 TRAF7 NF2
19 spinal canal and spinal cord meningioma 10.3 TRAF7 NF2
20 spinal meningioma 10.2 TRAF7 NF2
21 tanycytic ependymoma 10.2 NF2 GFAP
22 gemistocytic astrocytoma 10.2 IDH1 GFAP
23 intracranial meningioma 10.2
24 lymphoplasmacyte-rich meningioma 10.2
25 cerebellum cancer 10.2 IDH1 GFAP
26 anaplastic ependymoma 10.2 NF2 GFAP
27 mixed glioma 10.2 IDH1 GFAP
28 fibrous meningioma 10.2 TRAF7 NF2
29 chordoid glioma 10.2 NF2 GFAP
30 cranial nerve neoplasm 10.2 NF2 GFAP
31 angiomatous meningioma 10.2 TRAF7 NF2 AGGF1
32 gliofibroma 10.2 IDH1 GFAP
33 optic nerve glioma 10.2 NF2 GFAP
34 spinal cord glioma 10.2 NF2 IDH1
35 chordoid meningioma 10.2 TRAF7 NF2 GFAP
36 rhabdoid meningioma 10.2 TRAF7 NF2 GFAP
37 clear cell meningioma 10.2 TRAF7 NF2 GFAP
38 cellular ependymoma 10.1 NF2 GFAP
39 clear cell ependymoma 10.1 NF2 IDH1 GFAP
40 spinal cancer 10.1 NF2 IDH1 GFAP
41 supratentorial primitive neuroectodermal tumor 10.1 IDH1 GFAP
42 high grade ependymoma 10.1 NF2 IDH1 GFAP
43 benign ependymoma 10.1 NF2 IDH1 GFAP
44 cerebral ventricle cancer 10.1 NF2 IDH1 GFAP
45 cerebrum cancer 10.1 NF2 IDH1 GFAP
46 supratentorial cancer 10.1 NF2 IDH1 GFAP
47 myxopapillary ependymoma 10.1 NF2 GFAP
48 central nervous system benign neoplasm 10.1 NF2 IDH1 GFAP
49 mandibular cancer 10.1 GNAS GFAP
50 atypical teratoid rhabdoid tumor 10.1 NF2 IDH1 GFAP

Graphical network of the top 20 diseases related to Frontal Convexity Meningioma:



Diseases related to Frontal Convexity Meningioma

Symptoms & Phenotypes for Frontal Convexity Meningioma

UMLS symptoms related to Frontal Convexity Meningioma:


seizures; headache

GenomeRNAi Phenotypes related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 8.8 NF2 PDGFRB
2 Decreased cell migration GR00055-A-3 8.8 PIK3CA

MGI Mouse Phenotypes related to Frontal Convexity Meningioma:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.2 FGF10 FGFR4 GFAP GNAS IDH1 KLF4
2 cellular MP:0005384 10.19 AGGF1 FGF10 FGFR4 GFAP GNAS KLF4
3 homeostasis/metabolism MP:0005376 10.17 FGF10 FGFR4 GFAP GNAS IDH1 KLF4
4 mortality/aging MP:0010768 10.15 AGGF1 FGF10 FGFR4 GFAP GNAS IDH1
5 immune system MP:0005387 10.14 FGF10 FGFR4 GFAP GNAS IDH1 KLF4
6 digestive/alimentary MP:0005381 9.95 FGF10 GFAP KLF4 MMP7 PDGFRB TERT
7 neoplasm MP:0002006 9.92 AGGF1 FGFR4 GNAS KLF4 MMP7 NF2
8 nervous system MP:0003631 9.91 AGGF1 FGF10 GFAP GNAS KLF4 NF2
9 respiratory system MP:0005388 9.7 AGGF1 FGF10 FGFR4 GNAS IDH1 NF2
10 skeleton MP:0005390 9.56 FGF10 FGFR4 GNAS IDH1 NF2 PDGFRB
11 vision/eye MP:0005391 9.23 FGF10 FGFR4 GFAP KLF4 MMP7 NF2

Drugs & Therapeutics for Frontal Convexity Meningioma

Search Clinical Trials , NIH Clinical Center for Frontal Convexity Meningioma

Genetic Tests for Frontal Convexity Meningioma

Anatomical Context for Frontal Convexity Meningioma

MalaCards organs/tissues related to Frontal Convexity Meningioma:

40
Cortex, Tongue, Pituitary

Publications for Frontal Convexity Meningioma

Articles related to Frontal Convexity Meningioma:

(show all 17)
# Title Authors PMID Year
1
A case of meningolacrimal artery aneurysm associated with meningioma. 61
33654564 2021
2
5-aminolevulinic acid fluorescence guided surgery for resection of cystic meningioma with bone invasion. 61
33095079 2020
3
Acute cerebral venous outflow obstruction during convexity meningioma resection. 61
32729769 2020
4
Massive Secondary Cutaneous Meningioma with Extension to the Face. 61
32874712 2020
5
Coexistent pituitary adenoma and frontal convexity meningioma with frontal sinus invasion: A rare association. 61
33033632 2020
6
Cosmetic and Neuroprotective Placement of Custom-Made Ultra-High-Molecular-Weight Polyethylene Cranial Plate (SKULPIO) in Single-Step Surgery: Technical Note and Case Report. 61
31299307 2019
7
De novo brain arteriovenous malformation after tumor resection: case report and literature review. 61
30206686 2018
8
Frontal meningioma incidentally detected in the routine preoperative assessment of tongue cancer: a case report and literature review. 61
24237778 2013
9
A glioblastoma arising from the attached region where a meningioma had been totally removed. 61
21284750 2011
10
Primary brain tumors associated with cerebral aneurysm: report of three cases. 61
21534205 2011
11
Severe intraoperative air embolism during convexity meningioma surgery in the supine position. Case report. 61
12173393 2002
12
[A case of recurrent convexity meningioma with malignant transformation 26 years after total tumor removal]. 61
11218772 2001
13
[A case of asymptomatic meningioma at left frontal convexity: evaluation using of WAIS-R at preoperation and postoperation]. 61
10793422 2000
14
Utility of a moveable 1.5 Tesla intraoperative MR imaging system. 61
10563219 1999
15
Surgically responsive focal tremor associated with a frontal convexity meningioma. 61
9776628 1998
16
Detachment of desmosomes in a microcystic meningioma. 61
8867687 1995
17
Identification of the cerebral motor cortex by focal magnetic stimulation: clinical application to neurosurgical patients. 61
7624632 1994

Variations for Frontal Convexity Meningioma

Expression for Frontal Convexity Meningioma

Search GEO for disease gene expression data for Frontal Convexity Meningioma.

Pathways for Frontal Convexity Meningioma

Pathways related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.5 RPL32 PIK3CA PDGFRB IDH1 FGFR4 FGF10
2
Show member pathways
12.49 PIK3CA PDGFRB FGFR4 FGF10
3
Show member pathways
12.47 TERT PIK3CA PDGFRB GNAS FGFR4 FGF10
4
Show member pathways
12.43 PIK3CA PDGFRB GNAS FGF10
5 12.38 PIK3CA PDGFRB FGFR4 FGF10
6
Show member pathways
12.3 PIK3CA PDGFRB GNAS FGFR4 FGF10
7
Show member pathways
12.2 PIK3CA PDGFRB FGFR4 FGF10
8
Show member pathways
12.01 TERT PDGFRB FGFR4 FGF10
9 12 PDGFRB GNAS FGFR4 FGF10
10
Show member pathways
11.96 PIK3CA FGFR4 FGF10
11
Show member pathways
11.91 PIK3CA PDGFRB GNAS
12 11.87 PIK3CA KLF4 FGFR4
13 11.83 TERT PIK3CA PDGFRB GNAS FGFR4 FGF10
14 11.58 PDGFRB MMP7 FGFR4
15 11.51 GFAP FGFR4 FGF10
16 11.47 PDGFRB GNAS FGFR4 FGF10
17 11.39 PIK3CA PDGFRB IDH1
18 11.38 TERT PDGFRB KLF4 FGF10
19 11 PIK3CA PDGFRB
20 10.94 PIK3CA GNAS
21 10.93 PIK3CA PDGFRB
22 10.71 PDGFRB GNAS GFAP FGFR4 FGF10

GO Terms for Frontal Convexity Meningioma

Cellular components related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.36 TERT PIK3CA PDGFRB NF2 KLF4 IDH1

Biological processes related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to organic cyclic compound GO:0014070 9.43 PDGFRB IDH1 FGF10
2 positive regulation of DNA biosynthetic process GO:2000573 9.16 PDGFRB FGFR4
3 epidermis morphogenesis GO:0048730 8.96 KLF4 FGF10
4 positive regulation of protein kinase B signaling GO:0051897 8.92 PIK3CA PDGFRB FGFR4 FGF10

Molecular functions related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 8.8 MMP7 FGFR4 FGF10

Sources for Frontal Convexity Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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