Frontal Convexity Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Frontal Convexity Meningioma

MalaCards integrated aliases for Frontal Convexity Meningioma:

Name: Frontal Convexity Meningioma ¹¹ ¹⁴ ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:8000

NCIt ⁴⁹ C5292

UMLS ⁷¹ C1333643

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Summaries for Frontal Convexity Meningioma

MalaCards based summary: Frontal Convexity Meningioma is related to meningioma, familial and pituitary adenoma, and has symptoms including headache and seizures. An important gene associated with Frontal Convexity Meningioma is AGGF1 (Angiogenic Factor With G-Patch And FHA Domains 1), and among its related pathways/superpathways are Disease and Signal Transduction. Affiliated tissues include tongue, bone and brain, and related phenotypes are neoplasm and nervous system

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Related Diseases for Frontal Convexity Meningioma

Diseases related to Frontal Convexity Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	meningioma, familial	10.3
2	pituitary adenoma	10.1
3	adenoma	10.1
4	tremor	10.1
5	angiomatous meningioma	9.8	NF2 AGGF1
6	histone mutated tumor	9.4	H3C15 H3C14 H3C13
7	diffuse midline glioma, h3 k27m-mutant	9.4	H3C15 H3C14 H3C13
8	hutchinson-gilford progeria syndrome	9.3	H3C15 H3C14 H3C13
9	alpha-thalassemia	9.3	H3C15 H3C14 H3C13
10	diffuse large b-cell lymphoma	9.2	H3C15 H3C14 H3C13

Graphical network of the top 20 diseases related to Frontal Convexity Meningioma:

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Symptoms & Phenotypes for Frontal Convexity Meningioma

UMLS symptoms related to Frontal Convexity Meningioma:

headache; seizures

MGI Mouse Phenotypes related to Frontal Convexity Meningioma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	neoplasm	MP:0002006	9.77	AGGF1 H3C13 H3C14 H3C15 NF2
2	nervous system	MP:0003631	9.72	AGGF1 H3C13 H3C14 H3C15 NF2
3	embryo	MP:0005380	9.65	AGGF1 H3C13 H3C14 H3C15 NF2
4	behavior/neurological	MP:0005386	9.55	AGGF1 H3C13 H3C14 H3C15 NF2
5	vision/eye	MP:0005391	9.26	H3C13 H3C14 H3C15 NF2
6	mortality/aging	MP:0010768	9.02	AGGF1 H3C13 H3C14 H3C15 NF2

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Drugs & Therapeutics for Frontal Convexity Meningioma

Search Clinical Trials, NIH Clinical Center for Frontal Convexity Meningioma

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Genetic Tests for Frontal Convexity Meningioma

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Anatomical Context for Frontal Convexity Meningioma

Organs/tissues related to Frontal Convexity Meningioma:

MalaCards : Tongue, Bone, Brain, Cortex, Pituitary

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Publications for Frontal Convexity Meningioma

Articles related to Frontal Convexity Meningioma:

(show all 18)

#	Title	Authors	PMID	Year
1	Acute cerebral venous outflow obstruction during convexity meningioma resection. ⁶²	Shen B...Hu Y	32729769	2022
2	A Rare Case of Intracerebral Pneumocephalus Caused by Preexisting Multiple Bone Defects and Encephalocele after Resection of Meningioma. ⁶²	Ozaki D...Tominaga T	34012747	2021
3	A case of meningolacrimal artery aneurysm associated with meningioma. ⁶²	Kuroda H...Kishima H	33654564	2021
4	5-aminolevulinic acid fluorescence guided surgery for resection of cystic meningioma with bone invasion. ⁶²	Garcia Moreno R...Cabezudo Artero JM	33095079	2020
5	Massive Secondary Cutaneous Meningioma with Extension to the Face. ⁶²	Elarjani T...Hassounah M	32874712	2020
6	Coexistent pituitary adenoma and frontal convexity meningioma with frontal sinus invasion: A rare association. ⁶²	Gosal JS...Khera S	33033632	2020
7	Cosmetic and Neuroprotective Placement of Custom-Made Ultra-High-Molecular-Weight Polyethylene Cranial Plate (SKULPIO) in Single-Step Surgery: Technical Note and Case Report. ⁶²	Oishi T...Namba H	31299307	2019
8	De novo brain arteriovenous malformation after tumor resection: case report and literature review. ⁶²	Lo Presti A...Morgan MK	30206686	2018
9	Frontal meningioma incidentally detected in the routine preoperative assessment of tongue cancer: a case report and literature review. ⁶²	Sano K...Ohba S	24237778	2013
10	A glioblastoma arising from the attached region where a meningioma had been totally removed. ⁶²	Ohba S...Murakami H	21284750	2011
11	Primary brain tumors associated with cerebral aneurysm: report of three cases. ⁶²	Suslu HT...Bozbuga M	21534205	2011
12	Severe intraoperative air embolism during convexity meningioma surgery in the supine position. Case report. ⁶²	Gomez-Perals LF...Cabezudo JM	12173393	2002
13	[A case of recurrent convexity meningioma with malignant transformation 26 years after total tumor removal]. ⁶²	Ohta M...Takeshita I	11218772	2001
14	[A case of asymptomatic meningioma at left frontal convexity: evaluation using of WAIS-R at preoperation and postoperation]. ⁶²	Mizushima M...Watanabe T	10793422	2000
15	Utility of a moveable 1.5 Tesla intraoperative MR imaging system. ⁶²	Kaibara T...Sutherland GR	10563219	1999
16	Surgically responsive focal tremor associated with a frontal convexity meningioma. ⁶²	Evidente VG...Deen HG	9776628	1998
17	Detachment of desmosomes in a microcystic meningioma. ⁶²	Matsui S...Hirano A	8867687	1995
18	Identification of the cerebral motor cortex by focal magnetic stimulation: clinical application to neurosurgical patients. ⁶²	Asakura T...Baba K	7624632	1994

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Genes for Frontal Convexity Meningioma

Genes related to Frontal Convexity Meningioma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	AGGF1	Angiogenic Factor With G-Patch And FHA Domains 1	Protein Coding	4.73	DISEASES inferred ¹⁴
2	H3C14	H3 Clustered Histone 14	Protein Coding	4.73	DISEASES inferred ¹⁴
3	H3C15	H3 Clustered Histone 15	Protein Coding	4.72	DISEASES inferred ¹⁴
4	H3C13	H3 Clustered Histone 13	Protein Coding	4.72	DISEASES inferred ¹⁴
5	NF2	NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor	Protein Coding	4.4	DISEASES inferred ¹⁴

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Variations for Frontal Convexity Meningioma

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Expression for Frontal Convexity Meningioma

Search GEO for disease gene expression data for Frontal Convexity Meningioma.

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Pathways for Frontal Convexity Meningioma

Pathways related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

(show all 20)

#	Super pathways	Score	Top Affiliating Genes
1	Disease ⁶⁶ Show member pathways Infectious disease ⁶⁶	13.31	H3C15 H3C14 H3C13 AGGF1
2	Signal Transduction ⁶⁶	13.28	NF2 H3C15 H3C14 H3C13
3	Signaling by Rho GTPases ⁶⁶ Show member pathways RHO GTPase cycle ⁶⁶ RHO GTPase Effectors ⁶⁶ Signaling by Rho GTPases, Miro GTPases and RHOBTB3 ⁶⁶	13.18	NF2 H3C15 H3C14 H3C13
4	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	12.85	H3C15 H3C14 H3C13
5	Response to elevated platelet cytosolic Ca2+ ⁶⁶ Show member pathways Disinhibition of SNARE formation ⁶⁶ Hemostasis ⁶⁶ Platelet activation, signaling and aggregation ⁶⁶ Platelet degranulation ⁶⁶	12.82	H3C15 H3C14 H3C13
6	Assembly of the pre-replicative complex ⁶⁶ Show member pathways DNA Replication ⁶⁶ DNA Replication Pre-Initiation ⁶⁶ RUNX1 regulates transcription of genes involved in differentiation of HSCs ⁶⁶ Transcriptional regulation by RUNX1 ⁶⁶	12.67	H3C15 H3C14 H3C13
7	Golgi-to-ER retrograde transport ⁶⁶ Show member pathways COPI-dependent Golgi-to-ER retrograde traffic ⁶⁶ Factors involved in megakaryocyte development and platelet production ⁶⁶ Intra-Golgi and retrograde Golgi-to-ER traffic ⁶⁶ Kinesins ⁶⁶ MHC class II antigen presentation ⁶⁶	12.62	H3C15 H3C14 H3C13
8	Chromatin organization ⁶⁶ Show member pathways Chromatin modifying enzymes ⁶⁶ HATs acetylate histones ⁶⁶	12.54	H3C15 H3C14 H3C13
9	ESR-mediated signaling ⁶⁶ Show member pathways Estrogen-dependent gene expression ⁶⁶ RUNX1 regulates estrogen receptor mediated transcription ⁶⁶ Signaling by Nuclear Receptors ⁶⁶	12.52	H3C15 H3C14 H3C13
10	Signaling by WNT ⁶⁶ Show member pathways TCF dependent signaling in response to WNT ⁶⁶	12.42	H3C13 H3C14 H3C15
11	Pre-NOTCH Expression and Processing ⁶⁶ Show member pathways Defective LFNG causes SCDO3 ⁶⁶ Pre-NOTCH Processing in Golgi ⁶⁶ Pre-NOTCH Processing in the Endoplasmic Reticulum ⁶⁶ Pre-NOTCH Transcription and Translation ⁶⁶ Signaling by NOTCH ⁶⁶	12.32	H3C15 H3C14 H3C13
12	Cellular Senescence ⁶⁶ Show member pathways Oxidative Stress Induced Senescence ⁶⁶ Senescence-Associated Secretory Phenotype (SASP) ⁶⁶	12.27	H3C15 H3C14 H3C13
13	Meiosis ⁶⁶ Show member pathways Meiotic recombination ⁶⁶ Meiotic synapsis ⁶⁶ Reproduction ⁶⁶	12.24	H3C15 H3C14 H3C13
14	Gene Silencing by RNA ⁶⁶ Show member pathways Golgi Cisternae Pericentriolar Stack Reorganization ⁶⁶ MASTL Facilitates Mitotic Progression ⁶⁶ Mitotic Prophase ⁶⁶ RNAi Pathway ⁶⁴ Small interfering RNA (siRNA) biogenesis ⁶⁶ Transcriptional regulation by small RNAs ⁶⁶ tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis ⁶⁶	12.21	H3C15 H3C14 H3C13
15	HCMV Infection ⁶⁶ Show member pathways HCMV Early Events ⁶⁶ HCMV Late Events ⁶⁶	12.16	H3C15 H3C14 H3C13
16	Signaling events mediated by HDAC Class I ⁶¹ Show member pathways Signaling events mediated by HDAC Class II ⁶¹ Transcription Sin3 and NuRD in transcription regulation ²²	11.76	H3C15 H3C14 H3C13
17	PKMTs methylate histone lysines ⁶⁶ Show member pathways Histone modifications ⁷⁴	11.57	H3C15 H3C14 H3C13
18	Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome ⁷⁴	10.9	H3C15 H3C14 H3C13
19	Interleukin-7 signaling ⁶⁶	10.69	H3C15 H3C14 H3C13
20	FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma ⁷⁴	10.32	H3C15 H3C14 H3C13

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GO Terms for Frontal Convexity Meningioma

Cellular components related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	chromosome	GO:0005694	9.13	H3C15 H3C14 H3C13
2	nucleosome	GO:0000786	9.1	H3C15 H3C14 H3C13

Biological processes related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	nucleosome assembly	GO:0006334	9.1	H3C15 H3C14 H3C13

Molecular functions related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein heterodimerization activity	GO:0046982	9.43	H3C15 H3C14 H3C13
2	structural constituent of chromatin	GO:0030527	9.1	H3C15 H3C14 H3C13

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Sources for Frontal Convexity Meningioma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: FRN003 MIFTS: 25	Frontal Convexity Meningioma Categories: Cancer diseases, Neuronal diseases	Data Licensing For inquiries, contact: [email protected]
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