Frontal Convexity Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Frontal Convexity Meningioma

MalaCards integrated aliases for Frontal Convexity Meningioma:

Name: Frontal Convexity Meningioma ¹² ¹⁵ ⁷⁰

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:8000

NCIt ⁵⁰ C5292

UMLS ⁷⁰ C1333643

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Summaries for Frontal Convexity Meningioma

MalaCards based summary : Frontal Convexity Meningioma is related to secretory meningioma and meningioma, familial, and has symptoms including seizures and headache. An important gene associated with Frontal Convexity Meningioma is AGGF1 (Angiogenic Factor With G-Patch And FHA Domains 1), and among its related pathways/superpathways are HIV Life Cycle and Downstream signaling events of B Cell Receptor (BCR). Affiliated tissues include cortex, tongue and pituitary, and related phenotypes are Decreased cell migration and Decreased cell migration

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Related Diseases for Frontal Convexity Meningioma

Diseases related to Frontal Convexity Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)

#	Related Disease	Score	Top Affiliating Genes
1	secretory meningioma	30.3	TRAF7 NF2 KLF4
2	meningioma, familial	28.7	TRAF7 TERT PIK3CA PDGFRB NF2 KLF4
3	extraventricular neurocytoma	10.3	IDH1 GFAP
4	pediatric meningioma	10.3	TRAF7 NF2
5	intraventricular meningioma	10.3	TRAF7 NF2
6	olfactory groove meningioma	10.3	TRAF7 NF2
7	psammomatous meningioma	10.3	TRAF7 NF2
8	meninges hemangiopericytoma	10.3	TRAF7 NF2
9	anterior cranial fossa meningioma	10.3	TRAF7 NF2
10	cerebral convexity meningioma	10.3	NF2 IDH1
11	suprasellar meningioma	10.3	NF2 GFAP
12	brain meningioma	10.3	TRAF7 NF2
13	angiocentric glioma	10.3	IDH1 GFAP
14	intraneural perineurioma	10.3	TRAF7 NF2
15	spinal cord oligodendroglioma	10.3	IDH1 GFAP
16	papillary ependymoma	10.3	NF2 GFAP
17	transitional meningioma	10.3	TRAF7 NF2
18	meningothelial meningioma	10.3	TRAF7 NF2
19	spinal canal and spinal cord meningioma	10.3	TRAF7 NF2
20	spinal meningioma	10.2	TRAF7 NF2
21	tanycytic ependymoma	10.2	NF2 GFAP
22	gemistocytic astrocytoma	10.2	IDH1 GFAP
23	intracranial meningioma	10.2
24	lymphoplasmacyte-rich meningioma	10.2
25	cerebellum cancer	10.2	IDH1 GFAP
26	anaplastic ependymoma	10.2	NF2 GFAP
27	mixed glioma	10.2	IDH1 GFAP
28	fibrous meningioma	10.2	TRAF7 NF2
29	chordoid glioma	10.2	NF2 GFAP
30	cranial nerve neoplasm	10.2	NF2 GFAP
31	angiomatous meningioma	10.2	TRAF7 NF2 AGGF1
32	gliofibroma	10.2	IDH1 GFAP
33	optic nerve glioma	10.2	NF2 GFAP
34	spinal cord glioma	10.2	NF2 IDH1
35	chordoid meningioma	10.2	TRAF7 NF2 GFAP
36	rhabdoid meningioma	10.2	TRAF7 NF2 GFAP
37	clear cell meningioma	10.2	TRAF7 NF2 GFAP
38	cellular ependymoma	10.1	NF2 GFAP
39	clear cell ependymoma	10.1	NF2 IDH1 GFAP
40	spinal cancer	10.1	NF2 IDH1 GFAP
41	supratentorial primitive neuroectodermal tumor	10.1	IDH1 GFAP
42	high grade ependymoma	10.1	NF2 IDH1 GFAP
43	benign ependymoma	10.1	NF2 IDH1 GFAP
44	cerebral ventricle cancer	10.1	NF2 IDH1 GFAP
45	cerebrum cancer	10.1	NF2 IDH1 GFAP
46	supratentorial cancer	10.1	NF2 IDH1 GFAP
47	myxopapillary ependymoma	10.1	NF2 GFAP
48	central nervous system benign neoplasm	10.1	NF2 IDH1 GFAP
49	mandibular cancer	10.1	GNAS GFAP
50	atypical teratoid rhabdoid tumor	10.1	NF2 IDH1 GFAP

Graphical network of the top 20 diseases related to Frontal Convexity Meningioma:

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Symptoms & Phenotypes for Frontal Convexity Meningioma

UMLS symptoms related to Frontal Convexity Meningioma:

seizures; headache

GenomeRNAi Phenotypes related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased cell migration	GR00055-A-1	8.8	NF2 PDGFRB
2	Decreased cell migration	GR00055-A-3	8.8	PIK3CA

MGI Mouse Phenotypes related to Frontal Convexity Meningioma:

⁴⁶ (show all 11)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	growth/size/body region	MP:0005378	10.2	FGF10 FGFR4 GFAP GNAS IDH1 KLF4
2	cellular	MP:0005384	10.19	AGGF1 FGF10 FGFR4 GFAP GNAS KLF4
3	homeostasis/metabolism	MP:0005376	10.17	FGF10 FGFR4 GFAP GNAS IDH1 KLF4
4	mortality/aging	MP:0010768	10.15	AGGF1 FGF10 FGFR4 GFAP GNAS IDH1
5	immune system	MP:0005387	10.14	FGF10 FGFR4 GFAP GNAS IDH1 KLF4
6	digestive/alimentary	MP:0005381	9.95	FGF10 GFAP KLF4 MMP7 PDGFRB TERT
7	neoplasm	MP:0002006	9.92	AGGF1 FGFR4 GNAS KLF4 MMP7 NF2
8	nervous system	MP:0003631	9.91	AGGF1 FGF10 GFAP GNAS KLF4 NF2
9	respiratory system	MP:0005388	9.7	AGGF1 FGF10 FGFR4 GNAS IDH1 NF2
10	skeleton	MP:0005390	9.56	FGF10 FGFR4 GNAS IDH1 NF2 PDGFRB
11	vision/eye	MP:0005391	9.23	FGF10 FGFR4 GFAP KLF4 MMP7 NF2

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Drugs & Therapeutics for Frontal Convexity Meningioma

Search Clinical Trials , NIH Clinical Center for Frontal Convexity Meningioma

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Genetic Tests for Frontal Convexity Meningioma

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Anatomical Context for Frontal Convexity Meningioma

MalaCards organs/tissues related to Frontal Convexity Meningioma:

⁴⁰

Cortex, Tongue, Pituitary

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Publications for Frontal Convexity Meningioma

Articles related to Frontal Convexity Meningioma:

(show all 17)

#	Title	Authors	PMID	Year
1	A case of meningolacrimal artery aneurysm associated with meningioma. ⁶¹	Kuroda H...Kishima H	33654564	2021
2	5-aminolevulinic acid fluorescence guided surgery for resection of cystic meningioma with bone invasion. ⁶¹	Garcia Moreno R...Cabezudo Artero JM	33095079	2020
3	Acute cerebral venous outflow obstruction during convexity meningioma resection. ⁶¹	Shen B...Hu Y	32729769	2020
4	Massive Secondary Cutaneous Meningioma with Extension to the Face. ⁶¹	Elarjani T...Hassounah M	32874712	2020
5	Coexistent pituitary adenoma and frontal convexity meningioma with frontal sinus invasion: A rare association. ⁶¹	Gosal JS...Khera S	33033632	2020
6	Cosmetic and Neuroprotective Placement of Custom-Made Ultra-High-Molecular-Weight Polyethylene Cranial Plate (SKULPIO) in Single-Step Surgery: Technical Note and Case Report. ⁶¹	Oishi T...Namba H	31299307	2019
7	De novo brain arteriovenous malformation after tumor resection: case report and literature review. ⁶¹	Lo Presti A...Morgan MK	30206686	2018
8	Frontal meningioma incidentally detected in the routine preoperative assessment of tongue cancer: a case report and literature review. ⁶¹	Sano K...Ohba S	24237778	2013
9	A glioblastoma arising from the attached region where a meningioma had been totally removed. ⁶¹	Ohba S...Murakami H	21284750	2011
10	Primary brain tumors associated with cerebral aneurysm: report of three cases. ⁶¹	Suslu HT...Bozbuga M	21534205	2011
11	Severe intraoperative air embolism during convexity meningioma surgery in the supine position. Case report. ⁶¹	Gomez-Perals LF...Cabezudo JM	12173393	2002
12	[A case of recurrent convexity meningioma with malignant transformation 26 years after total tumor removal]. ⁶¹	Ohta M...Takeshita I	11218772	2001
13	[A case of asymptomatic meningioma at left frontal convexity: evaluation using of WAIS-R at preoperation and postoperation]. ⁶¹	Mizushima M...Watanabe T	10793422	2000
14	Utility of a moveable 1.5 Tesla intraoperative MR imaging system. ⁶¹	Kaibara T...Sutherland GR	10563219	1999
15	Surgically responsive focal tremor associated with a frontal convexity meningioma. ⁶¹	Evidente VG...Deen HG	9776628	1998
16	Detachment of desmosomes in a microcystic meningioma. ⁶¹	Matsui S...Hirano A	8867687	1995
17	Identification of the cerebral motor cortex by focal magnetic stimulation: clinical application to neurosurgical patients. ⁶¹	Asakura T...Baba K	7624632	1994

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Genes for Frontal Convexity Meningioma

Genes related to Frontal Convexity Meningioma (0 elite genes):

(show all 14)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	AGGF1	Angiogenic Factor With G-Patch And FHA Domains 1	Protein Coding	5.6	DISEASES inferred ¹⁵
2	TRAF7	TNF Receptor Associated Factor 7	Protein Coding	4.97	DISEASES inferred ¹⁵
3	RPL32	Ribosomal Protein L32	Protein Coding	4.9	DISEASES inferred ¹⁵
4	IDH1	Isocitrate Dehydrogenase (NADP(+)) 1	Protein Coding	4.81	DISEASES inferred ¹⁵
5	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	4.74	DISEASES inferred ¹⁵
6	NF2	Neurofibromin 2	Protein Coding	4.64	DISEASES inferred ¹⁵
7	FGF10	Fibroblast Growth Factor 10	Protein Coding	4.41	DISEASES inferred ¹⁵
8	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	4.37	DISEASES inferred ¹⁵
9	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	4.17	DISEASES inferred ¹⁵
10	GNAS	GNAS Complex Locus	Protein Coding	4.04	DISEASES inferred ¹⁵
11	MMP7	Matrix Metallopeptidase 7	Protein Coding	3.7	DISEASES inferred ¹⁵
12	KLF4	Kruppel Like Factor 4	Protein Coding	3.57	DISEASES inferred ¹⁵
13	TERT	Telomerase Reverse Transcriptase	Protein Coding	3.37	DISEASES inferred ¹⁵
14	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	3.21	DISEASES inferred ¹⁵

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Variations for Frontal Convexity Meningioma

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Expression for Frontal Convexity Meningioma

Search GEO for disease gene expression data for Frontal Convexity Meningioma.

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Pathways for Frontal Convexity Meningioma

Pathways related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

(show all 22)

#	Super pathways	Score	Top Affiliating Genes
1	HIV Life Cycle ⁶⁵ Show member pathways 2-LTR circle formation ⁶⁵ APOBEC3G mediated resistance to HIV-1 infection ⁶⁵ Assembly Of The HIV Virion ⁶⁵ Binding and entry of HIV virion ⁶⁵ Disease ⁶⁵ Diseases of signal transduction ⁶⁵ Early Phase of HIV Life Cycle ⁶⁵ HIV Infection ⁶⁵ Host Interactions of HIV factors ⁶⁵ Infectious disease ⁶⁵ Integration of provirus ⁶⁵ Late Phase of HIV Life Cycle ⁶⁵	13.5	RPL32 PIK3CA PDGFRB IDH1 FGFR4 FGF10
2	Downstream signaling events of B Cell Receptor (BCR) ⁶⁵ Show member pathways Activation of RAS in B cells ⁶⁵ Signaling by the B Cell Receptor (BCR) ⁶⁵	12.49	PIK3CA PDGFRB FGFR4 FGF10
3	PI3K-Akt signaling pathway ³⁶ Show member pathways Human papillomavirus infection ³⁶	12.47	TERT PIK3CA PDGFRB GNAS FGFR4 FGF10
4	Glioma ³⁶ Show member pathways Endocrine resistance ³⁶ Melanoma ³⁶ Non-small cell lung cancer ³⁶ Signaling Pathways in Glioblastoma ¹	12.43	PIK3CA PDGFRB GNAS FGF10
5	Regulation of actin cytoskeleton ¹ ³⁶	12.38	PIK3CA PDGFRB FGFR4 FGF10
6	Ras signaling pathway ³⁶ Show member pathways Rap1 signaling pathway ³⁶	12.3	PIK3CA PDGFRB GNAS FGFR4 FGF10
7	G-protein signaling RAC1 in cellular process ²³ Show member pathways CDC42 signaling events ¹ Cytoskeleton remodeling CDC42 in cellular processes ²³ RAC1 signaling pathway ¹	12.2	PIK3CA PDGFRB FGFR4 FGF10
8	Immune response IFN alpha/beta signaling pathway ²³ Show member pathways Cytokine Network ⁶³ Interferon alpha/beta signaling ⁶⁵ Regulation of IFNA signaling ⁶⁵	12.01	TERT PDGFRB FGFR4 FGF10
9	Calcium signaling pathway ³⁶	12	PDGFRB GNAS FGFR4 FGF10
10	Signaling by FGFR2 in disease ⁶⁵ Show member pathways FGFR2 mutant receptor activation ⁶⁵ Signaling by FGFR in disease ⁶⁵ Signaling by FGFR2 IIIa TM ⁶⁵	11.96	PIK3CA FGFR4 FGF10
11	Development EGFR signaling via small GTPases ²³ Show member pathways Development EGFR signaling via PIP3 ²³ Development PDGF signaling via MAPK cascades ²³ PDGF Pathway ¹	11.91	PIK3CA PDGFRB GNAS
12	Signaling pathways regulating pluripotency of stem cells ³⁶	11.87	PIK3CA KLF4 FGFR4
13	Pathways in cancer ³⁶	11.83	TERT PIK3CA PDGFRB GNAS FGFR4 FGF10
14	Angiogenesis (CST) ⁴	11.58	PDGFRB MMP7 FGFR4
15	Neural Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.51	GFAP FGFR4 FGF10
16	G-protein signaling_RhoA regulation pathway ²³	11.47	PDGFRB GNAS FGFR4 FGF10
17	Central carbon metabolism in cancer ³⁶	11.39	PIK3CA PDGFRB IDH1
18	Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.38	TERT PDGFRB KLF4 FGF10
19	Nectin adhesion pathway ¹	11	PIK3CA PDGFRB
20	Estrogen signaling pathway ¹	10.94	PIK3CA GNAS
21	Cytoskeleton remodeling_Role of PDGFs in cell migration ²³	10.93	PIK3CA PDGFRB
22	G-protein signaling_Rap2B regulation pathway ²³	10.71	PDGFRB GNAS GFAP FGFR4 FGF10

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GO Terms for Frontal Convexity Meningioma

Cellular components related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytoplasm	GO:0005737	9.36	TERT PIK3CA PDGFRB NF2 KLF4 IDH1

Biological processes related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	response to organic cyclic compound	GO:0014070	9.43	PDGFRB IDH1 FGF10
2	positive regulation of DNA biosynthetic process	GO:2000573	9.16	PDGFRB FGFR4
3	epidermis morphogenesis	GO:0048730	8.96	KLF4 FGF10
4	positive regulation of protein kinase B signaling	GO:0051897	8.92	PIK3CA PDGFRB FGFR4 FGF10

Molecular functions related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	heparin binding	GO:0008201	8.8	MMP7 FGFR4 FGF10

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Sources for Frontal Convexity Meningioma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Apr-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia