MCID: FRN003
MIFTS: 30

Frontal Convexity Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Frontal Convexity Meningioma

MalaCards integrated aliases for Frontal Convexity Meningioma:

Name: Frontal Convexity Meningioma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8000
NCIt 49 C5292
UMLS 71 C1333643

Summaries for Frontal Convexity Meningioma

MalaCards based summary : Frontal Convexity Meningioma is related to spinal meningioma and secretory meningioma, and has symptoms including seizures and headache. An important gene associated with Frontal Convexity Meningioma is AGGF1 (Angiogenic Factor With G-Patch And FHA Domains 1), and among its related pathways/superpathways are HIV Life Cycle and Class I MHC mediated antigen processing and presentation. Affiliated tissues include brain, cortex and tongue, and related phenotypes are Decreased cell migration and Decreased cell migration

Related Diseases for Frontal Convexity Meningioma

Diseases related to Frontal Convexity Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 spinal meningioma 30.7 TRAF7 NF2
2 secretory meningioma 30.3 TRAF7 NF2 KLF4
3 meningioma, familial 27.5 TRAF7 TERT RICTOR PIK3CA NF2 KLF4
4 extraventricular neurocytoma 10.5 IDH1 GFAP
5 pediatric meningioma 10.4 TRAF7 NF2
6 brain meningioma 10.4 TRAF7 NF2
7 olfactory groove meningioma 10.4 TRAF7 NF2
8 psammomatous meningioma 10.4 TRAF7 NF2
9 meninges hemangiopericytoma 10.4 TRAF7 NF2
10 suprasellar meningioma 10.4 NF2 GFAP
11 anterior cranial fossa meningioma 10.4 TRAF7 NF2
12 angiocentric glioma 10.4 IDH1 GFAP
13 tanycytic ependymoma 10.4 NF2 GFAP
14 transitional meningioma 10.4 TRAF7 NF2
15 spinal canal and spinal cord meningioma 10.4 TRAF7 NF2
16 spinal cord oligodendroglioma 10.4 IDH1 GFAP
17 angiomatous meningioma 10.4 TRAF7 NF2 AGGF1
18 anaplastic ependymoma 10.4 NF2 GFAP
19 parachordoma 10.4 S100A1 GFAP
20 cellular schwannoma 10.4 S100A1 NF2
21 intraventricular meningioma 10.3 TRAF7 NF2 MAGEC2
22 meningothelial meningioma 10.3 TRAF7 NF2
23 gemistocytic astrocytoma 10.3 IDH1 GFAP
24 rhabdoid meningioma 10.3 TRAF7 NF2 GFAP
25 clear cell meningioma 10.3 TRAF7 NF2 GFAP
26 clear cell ependymoma 10.3 IDH1 GFAP
27 intraneural perineurioma 10.3 TRAF7 S100A1 NF2
28 malignant ependymoma 10.3 NF2 IDH1 GFAP
29 cerebellum cancer 10.3 IDH1 GFAP
30 cerebrum cancer 10.3 NF2 IDH1 GFAP
31 cerebral ventricle cancer 10.3 NF2 IDH1 GFAP
32 supratentorial cancer 10.3 NF2 IDH1 GFAP
33 central nervous system benign neoplasm 10.3 NF2 IDH1 GFAP
34 multiple enchondromatosis, maffucci type 10.2 IDH1 GNAS AGGF1
35 juvenile pilocytic astrocytoma 10.2 PDGFRB IDH1 GFAP
36 mixed glioma 10.2 IDH1 GFAP
37 gliomatosis cerebri 10.2 IDH1 GFAP FGFR4
38 chordoid glioma 10.2 NF2 GFAP
39 spinal cancer 10.2 TRAF7 NF2 IDH1 GFAP
40 neuroma 10.1 NF2 GFAP FGFR4
41 obstructive hydrocephalus 10.1 RICTOR NF2 GFAP
42 chordoid meningioma 10.1 TRAF7 S100A1 NF2 GFAP
43 spinal cord disease 10.1 RICTOR NF2 GFAP
44 meningioma, radiation-induced 10.1
45 lymphoplasmacyte-rich meningioma 10.1
46 tremor 10.1
47 breast juvenile papillomatosis 10.1 PIK3CA GNAS
48 chordoma 10.1 S100A1 PDGFRB GFAP
49 skull base cancer 10.1 TRAF7 NF2 KLF4
50 skull base meningioma 10.1 TRAF7 NF2 KLF4

Graphical network of the top 20 diseases related to Frontal Convexity Meningioma:



Diseases related to Frontal Convexity Meningioma

Symptoms & Phenotypes for Frontal Convexity Meningioma

UMLS symptoms related to Frontal Convexity Meningioma:


seizures, headache

GenomeRNAi Phenotypes related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 9.28 NF2 RICTOR PDGFRB
2 Decreased cell migration GR00055-A-3 9.28 PIK3CA RICTOR

MGI Mouse Phenotypes related to Frontal Convexity Meningioma:

45 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.26 AGGF1 FGF10 FGFR4 GFAP GNAS KLF4
2 homeostasis/metabolism MP:0005376 10.25 FGF10 FGFR4 GFAP GNAS IDH1 KLF4
3 growth/size/body region MP:0005378 10.23 FGF10 FGFR4 GFAP GNAS IDH1 KLF4
4 immune system MP:0005387 10.21 FGF10 FGFR4 GFAP GNAS IDH1 KLF4
5 cardiovascular system MP:0005385 10.19 AGGF1 FGF10 GFAP GNAS KLF4 MMP7
6 hematopoietic system MP:0005397 10.17 FGF10 FGFR4 GNAS IDH1 KLF4 MMP7
7 mortality/aging MP:0010768 10.17 AGGF1 FGF10 FGFR4 GFAP GNAS IDH1
8 neoplasm MP:0002006 9.85 AGGF1 FGFR4 GNAS KLF4 MMP7 NF2
9 muscle MP:0005369 9.8 FGF10 GFAP GNAS PDGFRB PIK3CA RICTOR
10 respiratory system MP:0005388 9.56 AGGF1 FGF10 FGFR4 GNAS IDH1 NF2
11 skeleton MP:0005390 9.28 FGF10 FGFR4 GNAS IDH1 NF2 PDGFRB

Drugs & Therapeutics for Frontal Convexity Meningioma

Search Clinical Trials , NIH Clinical Center for Frontal Convexity Meningioma

Genetic Tests for Frontal Convexity Meningioma

Anatomical Context for Frontal Convexity Meningioma

MalaCards organs/tissues related to Frontal Convexity Meningioma:

40
Brain, Cortex, Tongue

Publications for Frontal Convexity Meningioma

Articles related to Frontal Convexity Meningioma:

(show all 12)
# Title Authors PMID Year
1
Cosmetic and Neuroprotective Placement of Custom-Made Ultra-High-Molecular-Weight Polyethylene Cranial Plate (SKULPIO) in Single-Step Surgery: Technical Note and Case Report. 61
31299307 2019
2
De novo brain arteriovenous malformation after tumor resection: case report and literature review. 61
30206686 2018
3
Frontal meningioma incidentally detected in the routine preoperative assessment of tongue cancer: a case report and literature review. 61
24237778 2013
4
A glioblastoma arising from the attached region where a meningioma had been totally removed. 61
21284750 2011
5
Primary brain tumors associated with cerebral aneurysm: report of three cases. 61
21534205 2011
6
Severe intraoperative air embolism during convexity meningioma surgery in the supine position. Case report. 61
12173393 2002
7
[A case of recurrent convexity meningioma with malignant transformation 26 years after total tumor removal]. 61
11218772 2001
8
[A case of asymptomatic meningioma at left frontal convexity: evaluation using of WAIS-R at preoperation and postoperation]. 61
10793422 2000
9
Utility of a moveable 1.5 Tesla intraoperative MR imaging system. 61
10563219 1999
10
Surgically responsive focal tremor associated with a frontal convexity meningioma. 61
9776628 1998
11
Detachment of desmosomes in a microcystic meningioma. 61
8867687 1995
12
Identification of the cerebral motor cortex by focal magnetic stimulation: clinical application to neurosurgical patients. 61
7624632 1994

Variations for Frontal Convexity Meningioma

Expression for Frontal Convexity Meningioma

Search GEO for disease gene expression data for Frontal Convexity Meningioma.

Pathways for Frontal Convexity Meningioma

Pathways related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.45 RPL32 RICTOR PSMB8 PIK3CA PDGFRB IDH1
2
Show member pathways
13.1 TRAF7 RICTOR PSMB8 PIK3CA PDGFRB NCF4
3
Show member pathways
12.68 TERT PIK3CA PDGFRB GNAS FGFR4 FGF10
4
Show member pathways
12.45 PIK3CA PDGFRB GNAS FGFR4 FGF10
5
Show member pathways
12.31 RICTOR PIK3CA PDGFRB FGFR4
6
Show member pathways
12.19 RICTOR PIK3CA FGFR4 FGF10
7 12.16 TERT PIK3CA PDGFRB GNAS FGFR4 FGF10
8
Show member pathways
12.04 RICTOR PIK3CA PDGFRB FGFR4
9
Show member pathways
11.86 TERT PSMB8 PDGFRB FGFR4 FGF10
10
Show member pathways
11.74 RICTOR PSMB8 PIK3CA PDGFRB FGFR4 FGF10
11 11.64 PDGFRB MMP7 FGFR4
12 11.58 TERT PDGFRB KLF4 FGF10
13 11.55 GFAP FGFR4 FGF10
14 11.54 PDGFRB GNAS FGFR4 FGF10
15 11.48 PIK3CA PDGFRB IDH1
16 10.83 PDGFRB GNAS GFAP FGFR4 FGF10

GO Terms for Frontal Convexity Meningioma

Cellular components related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.47 TERT S100A1 PSMB8 PIK3CA PDGFRB NF2
2 ruffle GO:0001726 9.13 PDGFRB NF2 GNAS

Biological processes related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.46 PSMB8 PDGFRB FGFR4 FGF10
2 positive regulation of catalytic activity GO:0043085 9.43 NCF4 GNAS FGFR4
3 positive regulation of DNA biosynthetic process GO:2000573 9.32 PDGFRB FGFR4
4 positive regulation of protein kinase B signaling GO:0051897 9.02 RICTOR PIK3CA PDGFRB FGFR4 FGF10
5 epidermis morphogenesis GO:0048730 8.96 KLF4 FGF10

Molecular functions related to Frontal Convexity Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.55 TRAF7 TERT S100A1 RICTOR PSMB8 PIK3CA

Sources for Frontal Convexity Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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