MCID: FRN058
MIFTS: 18

Frontal Sinus Benign Neoplasm

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Frontal Sinus Benign Neoplasm

MalaCards integrated aliases for Frontal Sinus Benign Neoplasm:

Name: Frontal Sinus Benign Neoplasm 12
Tumor of the Frontal Sinus 12
Neoplasm of Frontal Sinus 12
Frontal Sinus Neoplasm 15

Classifications:



External Ids:

Disease Ontology 12 DOID:1361
NCIt 49 C4419
SNOMED-CT 67 126678005
UMLS 71 C0345672

Summaries for Frontal Sinus Benign Neoplasm

MalaCards based summary : Frontal Sinus Benign Neoplasm, also known as tumor of the frontal sinus, is related to frontal sinus cancer and inverted papilloma. An important gene associated with Frontal Sinus Benign Neoplasm is KRT13 (Keratin 13), and among its related pathways/superpathways are Translation Non-genomic (rapid) action of Androgen Receptor and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Frontal Sinus Benign Neoplasm

Diseases related to Frontal Sinus Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 frontal sinus cancer 11.6
2 inverted papilloma 9.7 KRT5 KRT13
3 papilloma 9.7 KRT5 KRT13
4 skin benign neoplasm 9.7 KRT5 KRT13
5 mucoepidermoid carcinoma 9.6 KRT5 KRT13
6 breast ductal carcinoma 9.2 NME1 KRT5
7 frontal sinus inverted papilloma 8.4 POLK NME1 KRT5 KRT13 GRB2

Graphical network of the top 20 diseases related to Frontal Sinus Benign Neoplasm:



Diseases related to Frontal Sinus Benign Neoplasm

Symptoms & Phenotypes for Frontal Sinus Benign Neoplasm

GenomeRNAi Phenotypes related to Frontal Sinus Benign Neoplasm according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-119 9.44 NME1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.44 NME1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.44 KRT5
4 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.44 KRT5
5 Increased shRNA abundance (Z-score > 2) GR00366-A-17 9.44 KRT5
6 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.44 KRT5
7 Increased shRNA abundance (Z-score > 2) GR00366-A-200 9.44 KRT5
8 Increased shRNA abundance (Z-score > 2) GR00366-A-216 9.44 NME1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-53 9.44 NME1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.44 NME1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-75 9.44 NME1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.44 NME1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-91 9.44 KRT5

Drugs & Therapeutics for Frontal Sinus Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Frontal Sinus Benign Neoplasm

Genetic Tests for Frontal Sinus Benign Neoplasm

Anatomical Context for Frontal Sinus Benign Neoplasm

MalaCards organs/tissues related to Frontal Sinus Benign Neoplasm:

40
Bone

Publications for Frontal Sinus Benign Neoplasm

Articles related to Frontal Sinus Benign Neoplasm:

# Title Authors PMID Year
1
Giant cell tumor of the frontal sinus: a typical finding in an unlikely location. 61
29307940 2017
2
Primary carcinoid tumor of the frontal sinus: A case report. 61
20981647 2010
3
[Iatrogenic CSF leak as a complication of osteoplastic flap surgery of the frontal sinus]. 61
19886529 2009
4
Hemangiopericytoma: a rare head and neck tumor. 61
12759763 2003
5
[Unusual, biphasic differentiated mesenchyma tumor of the frontal sinus. Benign fibromyxo-osteoma]. 61
7844013 1994
6
[A rare case of the combination of a malignant tumor of the frontal sinus with a pyocele]. 61
3227616 1988
7
Collision tumor of the frontal sinus: evidence of prior intrasinus instillation of thorotrast. 61
6262586 1981
8
[Reconstruction of the skull defect using dimethyl polysiloxan (D.M.P.S.) following surgery of bone tumor of the frontal sinus]. 61
5106973 1971

Variations for Frontal Sinus Benign Neoplasm

Expression for Frontal Sinus Benign Neoplasm

Search GEO for disease gene expression data for Frontal Sinus Benign Neoplasm.

Pathways for Frontal Sinus Benign Neoplasm

Pathways related to Frontal Sinus Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.28 POLK GRB2
2
Show member pathways
10.83 KRT5 KRT13 GRB2

GO Terms for Frontal Sinus Benign Neoplasm

Cellular components related to Frontal Sinus Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.46 NME1 KRT5 KRT13 GRB2
2 keratin filament GO:0045095 8.96 KRT5 KRT13
3 intermediate filament GO:0005882 8.8 NME1 KRT5 KRT13

Biological processes related to Frontal Sinus Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.16 KRT5 KRT13
2 cytoskeleton organization GO:0007010 8.96 KRT5 KRT13
3 cornification GO:0070268 8.62 KRT5 KRT13

Sources for Frontal Sinus Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....