MCID: FRN005
MIFTS: 15

Frontal Sinus Squamous Cell Carcinoma

Categories: Cancer diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Frontal Sinus Squamous Cell Carcinoma

MalaCards integrated aliases for Frontal Sinus Squamous Cell Carcinoma:

Name: Frontal Sinus Squamous Cell Carcinoma 12 15 72
Epidermoid Carcinoma of the Frontal Sinus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2441
NCIt 50 C6067
UMLS 72 C1333646

Summaries for Frontal Sinus Squamous Cell Carcinoma

Disease Ontology : 12 A squamous cell carcinoma that is located in the frontal sinus.

MalaCards based summary : Frontal Sinus Squamous Cell Carcinoma, also known as epidermoid carcinoma of the frontal sinus, is related to squamous cell carcinoma and cholesteatoma of middle ear, and has symptoms including pain and rhinorrhea. An important gene associated with Frontal Sinus Squamous Cell Carcinoma is ANO1 (Anoctamin 1). Affiliated tissues include frontal sinus.

Related Diseases for Frontal Sinus Squamous Cell Carcinoma

Diseases related to Frontal Sinus Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 10.3
2 cholesteatoma of middle ear 10.1

Symptoms & Phenotypes for Frontal Sinus Squamous Cell Carcinoma

UMLS symptoms related to Frontal Sinus Squamous Cell Carcinoma:


pain, rhinorrhea

Drugs & Therapeutics for Frontal Sinus Squamous Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Frontal Sinus Squamous Cell Carcinoma

Genetic Tests for Frontal Sinus Squamous Cell Carcinoma

Anatomical Context for Frontal Sinus Squamous Cell Carcinoma

The Foundational Model of Anatomy Ontology organs/tissues related to Frontal Sinus Squamous Cell Carcinoma:

19
Frontal Sinus

Publications for Frontal Sinus Squamous Cell Carcinoma

Articles related to Frontal Sinus Squamous Cell Carcinoma:

# Title Authors PMID Year
1
Superior orbitectomy and chemotherapy in a dog with frontal sinus squamous cell carcinoma: a case report and review of the literature. 38
28396780 2017
2
Primary frontal sinus squamous cell carcinoma in a dog treated with surgical excision. 38
28042160 2017
3
Primary frontal sinus squamous cell carcinoma in three dogs treated with piroxicam combined with carboplatin or toceranib. 38
22236048 2012
4
Globe preservation surgery for a paranasal tumor with orbital extension. 38
20712512 2010
5
Primary squamous cell carcinoma of the frontal sinus treated with en bloc resection: case report. 38
19855148 2009
6
Epidermoid carcinoma of the frontal sinus secondary to cholesteatoma. 38
855080 1977

Variations for Frontal Sinus Squamous Cell Carcinoma

Cosmic variations for Frontal Sinus Squamous Cell Carcinoma:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM521 KRAS upper aerodigestive tract,sinus,carcinoma,undifferentiated carcinoma c.35G>A p.G12D 12:25245350-25245350 0

Expression for Frontal Sinus Squamous Cell Carcinoma

Search GEO for disease gene expression data for Frontal Sinus Squamous Cell Carcinoma.

Pathways for Frontal Sinus Squamous Cell Carcinoma

GO Terms for Frontal Sinus Squamous Cell Carcinoma

Sources for Frontal Sinus Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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