MCID: FRN005
MIFTS: 14

Frontal Sinus Squamous Cell Carcinoma

Categories: Cancer diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Frontal Sinus Squamous Cell Carcinoma

MalaCards integrated aliases for Frontal Sinus Squamous Cell Carcinoma:

Name: Frontal Sinus Squamous Cell Carcinoma 12 15 73
Epidermoid Carcinoma of the Frontal Sinus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2441
NCIt 50 C6067
UMLS 73 C1333646

Summaries for Frontal Sinus Squamous Cell Carcinoma

Disease Ontology : 12 A squamous cell carcinoma that is located in the frontal sinus.

MalaCards based summary : Frontal Sinus Squamous Cell Carcinoma, also known as epidermoid carcinoma of the frontal sinus, is related to squamous cell carcinoma, and has symptoms including pain and rhinorrhea. An important gene associated with Frontal Sinus Squamous Cell Carcinoma is ANO1 (Anoctamin 1). Affiliated tissues include skin and the frontal sinus.

Related Diseases for Frontal Sinus Squamous Cell Carcinoma

Diseases related to Frontal Sinus Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 10.3

Symptoms & Phenotypes for Frontal Sinus Squamous Cell Carcinoma

UMLS symptoms related to Frontal Sinus Squamous Cell Carcinoma:


pain, rhinorrhea

Drugs & Therapeutics for Frontal Sinus Squamous Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Frontal Sinus Squamous Cell Carcinoma

Genetic Tests for Frontal Sinus Squamous Cell Carcinoma

Anatomical Context for Frontal Sinus Squamous Cell Carcinoma

MalaCards organs/tissues related to Frontal Sinus Squamous Cell Carcinoma:

41
Skin

The Foundational Model of Anatomy Ontology organs/tissues related to Frontal Sinus Squamous Cell Carcinoma:

19
The Frontal Sinus

Publications for Frontal Sinus Squamous Cell Carcinoma

Articles related to Frontal Sinus Squamous Cell Carcinoma:

# Title Authors Year
1
Superior orbitectomy and chemotherapy in a dog with frontal sinus squamous cell carcinoma: a case report and review of the literature. ( 28396780 )
2017
2
Primary frontal sinus squamous cell carcinoma in a dog treated with surgical excision. ( 28042160 )
2017
3
Primary frontal sinus squamous cell carcinoma in three dogs treated with piroxicam combined with carboplatin or toceranib. ( 22236048 )
2012
4
Epidermoid carcinoma of the frontal sinus secondary to cholesteatoma. ( 855080 )
1977

Variations for Frontal Sinus Squamous Cell Carcinoma

Cosmic variations for Frontal Sinus Squamous Cell Carcinoma:

9 (show all 49)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM1610880 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.97-1G>T p.? 17:7676273-7676273 11
2 COSM10704 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.844C>T p.R282W 17:7673776-7673776 11
3 COSM43881 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.757A>T p.T253S 17:7674206-7674206 11
4 COSM44097 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.530C>T p.P177L 17:7675082-7675082 11
5 COSM43555 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.736A>G p.M246V 17:7674227-7674227 11
6 COSM10660 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.818G>A p.R273H 17:7673802-7673802 11
7 COSM43962 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.805A>G p.S269G 17:7673815-7673815 11
8 COSM10648 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.524G>A p.R175H 17:7675088-7675088 11
9 COSM10659 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.817C>T p.R273C 17:7673803-7673803 11
10 COSM44338 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.845G>A p.R282Q 17:7673775-7673775 11
11 COSM45046 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.542G>C p.R181P 17:7675070-7675070 11
12 COSM10647 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.404G>T p.C135F 17:7675208-7675208 11
13 COSM10654 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.637C>T p.R213* 17:7674894-7674894 11
14 COSM10651 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.530C>G p.P177R 17:7675082-7675082 11
15 COSM27173 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.360G>T p.K120N 17:7676009-7676009 11
16 COSM44312 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.511G>A p.E171K 17:7675101-7675101 11
17 COSM10656 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.742C>T p.R248W 17:7674221-7674221 11
18 COSM10650 TP53 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.529C>T p.P177S 17:7675083-7675083 11
19 COSM4531793 SUZ12 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.1825G>A p.G609R 17:31996828-31996828 11
20 COSM6973197 SUZ12 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.1639G>C p.E547Q 17:31995607-31995607 11
21 COSM6973188 NSD1 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.5074C>G p.H1692D 5:177260096-177260096 11
22 COSM581 NRAS upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.181C>G p.Q61E 1:114713909-114713909 11
23 COSM6973198 NOTCH3 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.2641G>A p.G881S 19:15181727-15181727 11
24 COSM6973185 NOTCH2 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.5458G>C p.D1820H 1:119920250-119920250 11
25 COSM120958 NFE2L2 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.235G>C p.E79Q 2:177234082-177234082 11
26 COSM6973195 LATS2 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.2827G>C p.E943Q 13:20975310-20975310 11
27 COSM551 KRAS upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.182A>C p.Q61P 12:25227342-25227342 11
28 COSM518 KRAS upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.34G>C p.G12R 12:25245351-25245351 11
29 COSM487 HRAS upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.37G>A p.G13S 11:534286-534286 11
30 COSM500 HRAS upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.182A>C p.Q61P 11:533874-533874 11
31 COSM6973196 GRIN2A upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.2008T>A p.F670I 16:9822424-9822424 11
32 COSM6960306 ETV1 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.755C>G p.P252R 7:13931549-13931549 11
33 COSM6960303 EPHA3 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.2945C>T p.P982L 3:89479495-89479495 11
34 COSM6942122 CDK12 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.2045C>T p.P682L 17:39490670-39490670 11
35 COSM5967148 ARID1A upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.3446C>G p.S1149* 1:26772539-26772539 11
36 COSM3937615 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.360G>T p.K120N 17:7676009-7676009 11
37 COSM1610881 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.97-1G>T p.? 17:7676273-7676273 11
38 COSM1610882 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.97-1G>T p.? 17:7676273-7676273 11
39 COSM3717684 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.97-1G>T p.? 17:7676273-7676273 11
40 COSM2744988 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.360G>T p.K120N 17:7676009-7676009 11
41 COSM3717685 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.97-1G>T p.? 17:7676273-7676273 11
42 COSM6973194 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.2827G>C p.E943Q 13:20975310-20975310 11
43 COSM6960305 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.635C>G p.P212R 7:13931549-13931549 11
44 COSM6973189 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.5074C>G p.H1692D 5:177260096-177260096 11
45 COSM2744989 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.360G>T p.K120N 17:7676009-7676009 11
46 COSM6973199 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.2641G>A p.G881S 19:15181727-15181727 11
47 COSM2744987 upper aerodigestive tract,sinus,carcinoma,squamous cell carcinoma c.360G>T p.K120N 17:7676009-7676009 11
48 COSM6441198 RB1 upper aerodigestive tract,sinus,carcinoma,undifferentiated carcinoma c.940-1G>A p.? 13:48367493-48367493 8
49 COSM521 KRAS upper aerodigestive tract,sinus,carcinoma,undifferentiated carcinoma c.35G>A p.G12D 12:25245350-25245350 8

Expression for Frontal Sinus Squamous Cell Carcinoma

Search GEO for disease gene expression data for Frontal Sinus Squamous Cell Carcinoma.

Pathways for Frontal Sinus Squamous Cell Carcinoma

GO Terms for Frontal Sinus Squamous Cell Carcinoma

Sources for Frontal Sinus Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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