MCID: FRN011
MIFTS: 28

Frontal Sinusitis

Categories: Respiratory diseases

Aliases & Classifications for Frontal Sinusitis

MalaCards integrated aliases for Frontal Sinusitis:

Name: Frontal Sinusitis 12 44 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:10791
MeSH 44 D015522
NCIt 50 C34626
SNOMED-CT 67 275485006
ICD10 32 J32.1
UMLS 70 C0016735

Summaries for Frontal Sinusitis

Disease Ontology : 12 A sinusitis which involves infection of the frontal sinuses over the eyes in the brow area. This causes pain or pressure in the frontal sinus cavity and headache over the forehead.

MalaCards based summary : Frontal Sinusitis is related to acute frontal sinusitis and ethmoid sinusitis. An important gene associated with Frontal Sinusitis is ARHGEF16 (Rho Guanine Nucleotide Exchange Factor 16). The drugs Triamcinolone and mometasone furoate have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and pituitary.

Related Diseases for Frontal Sinusitis

Diseases in the Frontal Sinusitis family:

Chronic Frontal Sinusitis Acute Frontal Sinusitis

Diseases related to Frontal Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 133)
# Related Disease Score Top Affiliating Genes
1 acute frontal sinusitis 31.9 PRTN3 HTR1B CYP2B6
2 ethmoid sinusitis 29.9 PRTN3 CRP
3 maxillary sinusitis 29.9 PRTN3 CRP
4 paranasal sinus disease 29.5 PRTN3 CRP
5 migraine with or without aura 1 29.5 HTR1B CRP ARHGEF16
6 chronic frontal sinusitis 11.7
7 osteomyelitis 10.7
8 pleural empyema 10.6
9 subdural empyema 10.5
10 epidural abscess 10.5
11 cellulitis 10.4
12 intracranial abscess 10.3
13 haemophilus influenzae 10.3
14 rhinitis 10.3
15 spastic paraplegia, intellectual disability, nystagmus, and obesity 10.2
16 orbital cellulitis 10.2
17 cavernous sinus thrombosis 10.2
18 allergic rhinitis 10.1
19 thrombosis 10.1
20 thrombophlebitis 10.1
21 exophthalmos 10.1
22 meningioma, familial 10.0
23 intracranial meningioma 10.0
24 bone inflammation disease 10.0
25 secretory meningioma 10.0
26 lymphoplasmacyte-rich meningioma 10.0
27 chronic rhinitis 10.0
28 severe cutaneous adverse reaction 10.0 CYP2B6 CRP
29 angina pectoris 9.9 HTR1B CRP
30 purulent acute otitis media 9.9 PRTN3 CRP
31 anterior scleritis 9.9 PRTN3 CRP
32 scleritis 9.9 PRTN3 CRP
33 orbital plasma cell granuloma 9.9 PRTN3 CRP
34 bicipital tenosynovitis 9.9 PRTN3 CRP
35 tenosynovitis 9.9 PRTN3 CRP
36 synovitis 9.9 PRTN3 CRP
37 multiple cranial nerve palsy 9.9 PRTN3 CRP
38 cranial nerve palsy 9.9 PRTN3 CRP
39 posterior scleritis 9.9 PRTN3 CRP
40 tolosa-hunt syndrome 9.9 PRTN3 CRP
41 chronic orbital inflammation 9.9 PRTN3 CRP
42 glossopharyngeal nerve disease 9.9 PRTN3 CRP
43 granulomatous angiitis 9.9 PRTN3 CRP
44 cholesterol embolism 9.9 PRTN3 CRP
45 mononeuritis of upper limb and mononeuritis multiplex 9.9 PRTN3 CRP
46 mononeuritis multiplex 9.9 PRTN3 CRP
47 splenic tuberculosis 9.9 PRTN3 CRP
48 subacute bacterial endocarditis 9.9 PRTN3 CRP
49 branch retinal artery occlusion 9.9 PRTN3 CRP
50 mastoiditis 9.9 PRTN3 CRP

Graphical network of the top 20 diseases related to Frontal Sinusitis:



Diseases related to Frontal Sinusitis

Symptoms & Phenotypes for Frontal Sinusitis

Drugs & Therapeutics for Frontal Sinusitis

Drugs for Frontal Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved 124-94-7 31307
2
mometasone furoate Approved, Investigational, Vet_approved 83919-23-7
3 Triamcinolone diacetate
4 triamcinolone acetonide
5 Triamcinolone hexacetonide

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Medico-economic Evaluation of the Balloon Sinuplasty as Mini-invasive Treatment of Frontal Sinusitis by a Randomized Multicenter Prospective Trial Terminated NCT02509663
2 Randomized Trial of Propel Stent vs Kenalog-soaked Nasopore After Frontal Drill-out Terminated NCT03534362
3 Prospective Study for Improvement in Outcomes Following Draf III/Endoscopic Modified Lothrop Procedure Using a Porcine Intestinal Submucosal Graft Withdrawn NCT02981017

Search NIH Clinical Center for Frontal Sinusitis

Cochrane evidence based reviews: frontal sinusitis

Genetic Tests for Frontal Sinusitis

Anatomical Context for Frontal Sinusitis

MalaCards organs/tissues related to Frontal Sinusitis:

40
Bone, Brain, Pituitary, Myeloid

Publications for Frontal Sinusitis

Articles related to Frontal Sinusitis:

(show top 50) (show all 728)
# Title Authors PMID Year
1
Complicated acute frontal sinusitis in a child presenting with acute ischemic stroke. 61
33508675 2021
2
Endoscopic management of frontal sinus diseases after frontal craniotomy: a case series and review of the literature. 61
32880737 2021
3
The impact of bolgerization versus partial resection of the middle turbinate on frontal sinusotomy patency outcome: A randomised controlled study. 61
33730409 2021
4
Bone wax-induced recurrent frontal sinusitis after skull base surgery. 61
32446646 2021
5
Comparison between the endoscopic scores of bolgerization versus partial resection of the middle turbinate for management of the postoperative lateralization in the early follow-up period after endoscopic frontal sinusotomy: A randomized controlled study. 61
33780901 2021
6
Does Sinusitis Affect Lateralization of a Tuning Fork Weber Test? 61
33661238 2021
7
The Prognostic Variables Affecting the Frontal Sinusotomy Patency Outcome and How to Manage: A Prospective Study. 61
33745238 2021
8
Epstein-Barr virus-positive diffuse large B-cell lymphoma with human immunodeficiency virus mimicking complicated frontal sinusitis: A case report. 61
33728309 2021
9
Resonance Effect of the Frontal Sinus on Ocular Vestibular-Evoked Myogenic Potential Recordings. 61
33735909 2021
10
Superiorly based subperiosteal orbital abscess: an uncommon presentation. 61
33602772 2021
11
Hypernasality after the endoscopic modified Lothrop procedure for refractory frontal sinusitis. 61
33641254 2021
12
Isolated Frontal Sinusitis and Anosmia: A Novel Presentation. 61
33425694 2021
13
Clinical and Radiologic Characterization of Frontal Sinusitis in the Pediatric Population. 61
33435715 2021
14
Brain abscess caused by dental peri-implantitis. 61
32636086 2021
15
A Case of Pott's Puffy Tumor Associated With Barosinusitis From Scuba Diving. 61
30601343 2021
16
Pott's puffy tumor in a 23-month-old: Youngest known case of a rare disease. 61
33422370 2021
17
Pott's puffy tumour in an immunosuppressed adult: case report and systematic review of literature. 61
33391653 2020
18
Dr. Ahila's Conchal Crusher for Concha Bullosa. 61
33088779 2020
19
The serious complications of frontal sinusitis, a case series and literature review. 61
33425318 2020
20
Frontal sinusitis associated with orbital decompression for Graves' orbitopathy. 61
32088015 2020
21
Indications and Outcomes of the Osteoplastic Flap Procedure With or Without Obliteration. 61
33136864 2020
22
Pott Puffy Tumor in Adults: The Τiming of Surgical Ιntervention. 61
33409028 2020
23
Computed tomographic analysis of the prevalence of International Frontal Sinus Anatomy Classification cells and their association with frontal sinusitis. 61
33054871 2020
24
Dual Purpose of De-Epithelialized Latissimus Dorsi Musculocutaneous Flap for Treatment of Chronic Frontal Sinusitis and Frontal Bone Defect. 61
32969937 2020
25
Odontogenic Sinusitis-Associated Pott's Puffy Tumor: A Case Report and Literature Review. 61
32921154 2020
26
Surgical treatment of frontal sinus osteoma. 61
32367154 2020
27
Intracranial abscesses in children at Ile-Ife, Nigeria: a case series and review of literature. 61
32034520 2020
28
Pott's Puffy Tumor: Intracranial Extension Not Requiring Neurosurgical Intervention. 61
33005524 2020
29
Partial resolution of chronic unilateral sinonasal obstructive disease in a cat using a temporary polyvinylchloride stent. 61
32843988 2020
30
Indications and Outcomes of the Osteoplastic Flap Procedure With or Without Obliteration. 61
32649533 2020
31
[Clinical application of Draf type Ⅲ frontal sinus surgery and pedicled septal mucosal flap in recurrent eosinophilic frontal sinusitis with nasal polyps]. 61
32842191 2020
32
Pott's Puffy Tumor and Intranasal Cocaine Abuse. 61
32310872 2020
33
Questioning the Justification of Frontal Sinusotomy for Odontogenic Sinusitis. 61
32008989 2020
34
Early experience with feasibility of balloon sinus dilation in complicated pediatric acute frontal rhinosinusitis. 61
32337348 2020
35
Trauma-associated Pott's puffy tumor: an ophthalmologic perspective. 61
30773962 2020
36
Management and Surveillance of Frontal Sinus Violation following Craniotomy. 61
32021743 2020
37
Neuronavigation-Guided Endoscopic Endonasal Drainage of Pediatric Anterior Cranial Base Epidural and Subdural Empyema. 61
31962318 2020
38
A rare case in childhood: Pott's puffy tumor developing secondary to frontal sinus osteoma. 61
33414666 2020
39
A Rare Case of Palpebral Cellulitis, a Variation of Pott's Puffy Tumor. 61
32308611 2020
40
Very painful acute frontal sinusitis revealing granulomatosis with polyangiitis. 61
31395462 2019
41
Free mucosal grafts and anterior pedicled flaps to prevent ostium restenosis after endoscopic modified Lothrop (frontal drillout) procedure: a randomized, controlled study. 61
31550080 2019
42
Functional Endoscopic Sinus Surgery of Nasal Polyposis: The Vexing Question of Whether to Resect or Preserve Middle Turbinate. 61
31763287 2019
43
Management of Frontal Bone Fractures. 61
31261348 2019
44
Frontal sinusitis in adult beef bulls: 18 cases (1999-2014). 61
31429647 2019
45
The Role of Free Tissue Transfer in the Management of Chronic Frontal Sinus Osteomyelitis. 61
30549281 2019
46
Pott's puffy tumor by Actinomyces after minor head trauma. 61
30060994 2019
47
Orbital abscess as a complication of Pott's puffy tumour in an adolescent male. 61
31315845 2019
48
[The novel Propel mini stent - Indications, surgical technique and first clinical experience]. 61
30802928 2019
49
[A case report of epidural abscess caused by acute frontal sinusitis]. 61
30808150 2019
50
The Relationship Between the Width of the Frontal Recess and the Frontal Recess Cells in Japanese Patients. 61
31700254 2019

Variations for Frontal Sinusitis

Expression for Frontal Sinusitis

Search GEO for disease gene expression data for Frontal Sinusitis.

Pathways for Frontal Sinusitis

GO Terms for Frontal Sinusitis

Biological processes related to Frontal Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vasoconstriction GO:0042310 8.62 HTR1B CRP

Sources for Frontal Sinusitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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