Aliases & Classifications for Fructose Utilization

MalaCards integrated aliases for Fructose Utilization:

Name: Fructose Utilization 57

Characteristics:

OMIM:

57
Inheritance:
autosomal recessive


HPO:

32
fructose utilization:
Inheritance autosomal recessive inheritance


External Ids:

OMIM 57 229650
MedGen 42 C1856672
SNOMED-CT via HPO 69 258211005

Summaries for Fructose Utilization

MalaCards based summary : Fructose Utilization is related to glioma and leukemia, acute myeloid. An important gene associated with Fructose Utilization is SLC2A5 (Solute Carrier Family 2 Member 5). Affiliated tissues include lung, myeloid and pancreatic islet.

Description from OMIM: 229650

Related Diseases for Fructose Utilization

Diseases related to Fructose Utilization via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 glioma 9.9
2 leukemia, acute myeloid 9.8
3 lung cancer susceptibility 3 9.8
4 adenocarcinoma 9.8
5 myeloid leukemia 9.8

Graphical network of the top 20 diseases related to Fructose Utilization:



Diseases related to Fructose Utilization

Symptoms & Phenotypes for Fructose Utilization

Symptoms via clinical synopsis from OMIM:

57
Misc:
cultured cells unable to use fructose for glucose


Clinical features from OMIM:

229650

Drugs & Therapeutics for Fructose Utilization

Search Clinical Trials , NIH Clinical Center for Fructose Utilization

Genetic Tests for Fructose Utilization

Anatomical Context for Fructose Utilization

MalaCards organs/tissues related to Fructose Utilization:

41
Lung, Myeloid, Pancreatic Islet

Publications for Fructose Utilization

Articles related to Fructose Utilization:

(show all 41)
# Title Authors Year
1
GLUT5 increases fructose utilization and promotes tumor progression in glioma. ( 29660339 )
2018
2
<i>SLC2A5</i> promotes lung adenocarcinoma cell growth and metastasis by enhancing fructose utilization. ( 29531835 )
2018
3
Ketohexokinase is involved in fructose utilization and promotes tumor progression in glioma. ( 30031605 )
2018
4
Improving Fructose Utilization and Butanol Production by Clostridium acetobutylicum via Extracellular Redox Potential Regulation and Intracellular Metabolite Analysis. ( 28731563 )
2017
5
Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential. ( 27746145 )
2016
6
Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization. ( 22822162 )
2012
7
Glial-neuronal interactions underlying fructose utilization in rat hippocampal slices. ( 19362122 )
2009
8
Molecular basis of fructose utilization by the wine yeast Saccharomyces cerevisiae: a mutated HXT3 allele enhances fructose fermentation. ( 17308189 )
2007
9
A route for fructose utilization by Escherichia coli involving the fucose regulon. ( 17159144 )
2006
10
Characterization of genes involved in fructose utilization by Lactobacillus fermentum. ( 16741753 )
2006
11
Fructose utilization in Lactococcus lactis as a model for low-GC gram-positive bacteria: its regulator, signal, and DNA-binding site. ( 15901699 )
2005
12
Comparison between D-[3-3H]- and D-[5-3H]glucose and fructose utilization in pancreatic islets from control and hereditarily diabetic rats. ( 12485609 )
2002
13
Routes for fructose utilization by Escherichia coli. ( 11361065 )
2001
14
Fructose utilization and phytopathogenicity of Spiroplasma citri. ( 11043476 )
2000
15
Fructose utilization and pathogenicity of Spiroplasma citri: characterization of the fructose operon. ( 10903438 )
2000
16
Fructose utilization by the human intestinal epithelial cell line, Caco-2. ( 8456108 )
1993
17
Fructose utilization during exercise in men: rapid conversion of ingested fructose to circulating glucose. ( 8335542 )
1993
18
Effect of cyclic AMP on fructose utilization, progressive motility and protein synthesis by ram spermatozoa. ( 16727104 )
1992
19
An investigation of fructose utilization in Acanthocheilonema viteae. ( 2092300 )
1990
20
Location and function of fruC, a gene involved in the regulation of fructose utilization by Escherichia coli. ( 3309151 )
1987
21
Nutritional and hormonal control of glucose and fructose utilization by lung. ( 3902322 )
1985
22
Glucose and fructose utilization in human platelets. Effects of diamide. ( 6511296 )
1984
23
Fructose utilization by lung. ( 6323366 )
1984
24
Fructose utilization for nucleic acid synthesis in the fetal pig. ( 6181047 )
1982
25
THC effects on fructose utilization and sperm motility. ( 6277701 )
1982
26
Enzymes related to fructose utilization in Pseudomonas cepacia. ( 6281243 )
1982
27
delta 9-tetrahydrocannabinol inhibits fructose utilization and motility in human, rhesus monkey, and rabbit sperm in vitro. ( 6265292 )
1981
28
Glucose and fructose utilization by rat spermatozoa within the uterine lumen. ( 7205789 )
1981
29
Fructose utilization and altered cytochrome P-450 in cultured hepatocytes from adult rats. ( 7459390 )
1980
30
Kinetics of fructose utilization by buffalo spermatozoa. ( 547827 )
1979
31
Genetical analysis of fructose utilization by Escherichia coli. ( 4154035 )
1974
32
Factors affecting fructose utilization and lactic acid formation by human semen. The role of glucose and pyruvic acid. ( 5115101 )
1971
33
Pathway of fructose utilization by Escherichia coli. ( 11945648 )
1971
34
Role of fructose-1,6-diphosphatase in fructose utilization by Escherichia coli. ( 11945798 )
1971
35
Fructose utilization by the baby pig. ( 4911989 )
1970
36
Effects of deoxyfrenolicin on isolated adipose cells. I. Glucose and fructose utilization. ( 4306959 )
1969
37
Effects of Bacillus subtilis protease, type 8 (subtilopeptidase A) on isolated adipose cells. Fructose utilization and its inhibition by avenaciolide, piericidin A and puromycin. ( 4971641 )
1968
38
Fructose utilization of human spermatozoa after cooling and freezing. ( 12471676 )
1967
39
The influence of amino acids on fructose utilization in the luminous bacterium, Achromobacter fischeri. ( 13162998 )
1954
40
Effect of castration and steroid therapy on seminal plasma with respect to fructose utilization by normal bull sperm. ( 13047308 )
1952
41
Fructose utilization by Pseudomonas putrefaciens. ( 14832193 )
1951

Variations for Fructose Utilization

Expression for Fructose Utilization

Search GEO for disease gene expression data for Fructose Utilization.

Pathways for Fructose Utilization

GO Terms for Fructose Utilization

Sources for Fructose Utilization

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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