Aliases & Classifications for Fructose Utilization

MalaCards integrated aliases for Fructose Utilization:

Name: Fructose Utilization 57

Characteristics:

OMIM®:

57 (Updated 05-Apr-2021)
Inheritance:
autosomal recessive


HPO:

31
fructose utilization:
Inheritance autosomal recessive inheritance


External Ids:

OMIM® 57 229650
MedGen 41 C1856672
SNOMED-CT via HPO 68 258211005

Summaries for Fructose Utilization

MalaCards based summary : Fructose Utilization is related to glioma and glial tumor. An important gene associated with Fructose Utilization is SLC2A5 (Solute Carrier Family 2 Member 5). Affiliated tissues include lung, testis and myeloid.

More information from OMIM: 229650

Related Diseases for Fructose Utilization

Diseases related to Fructose Utilization via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 glioma 10.0
2 glial tumor 10.0
3 renal cell carcinoma, nonpapillary 9.9
4 ovarian cancer 9.9
5 lung cancer 9.9
6 leukemia, acute myeloid 9.9
7 lung cancer susceptibility 3 9.9
8 leukemia 9.9
9 adenocarcinoma 9.9
10 clear cell renal cell carcinoma 9.9
11 myeloid leukemia 9.9

Graphical network of the top 20 diseases related to Fructose Utilization:



Diseases related to Fructose Utilization

Symptoms & Phenotypes for Fructose Utilization

Symptoms via clinical synopsis from OMIM®:

57 (Updated 05-Apr-2021)
Misc:
cultured cells unable to use fructose for glucose

Clinical features from OMIM®:

229650 (Updated 05-Apr-2021)

Drugs & Therapeutics for Fructose Utilization

Search Clinical Trials , NIH Clinical Center for Fructose Utilization

Genetic Tests for Fructose Utilization

Anatomical Context for Fructose Utilization

MalaCards organs/tissues related to Fructose Utilization:

40
Lung, Testis, Myeloid, Pancreatic Islet

Publications for Fructose Utilization

Articles related to Fructose Utilization:

(show top 50) (show all 97)
# Title Authors PMID Year
1
X-ray dose response for mutation to fructose utilisation in cultured diploid human fibroblasts. 57
4431451 1974
2
Evaluation of lactic acid bacteria strains isolated from fructose-rich environments for their mannitol-production and milk-gelation abilities. 61
33010917 2020
3
Tissue-Specific Fructose Metabolism in Obesity and Diabetes. 61
33057854 2020
4
Determining the contribution of a high-fructose corn syrup formulation to hepatic glycogen synthesis during ad-libitum feeding in mice. 61
32733017 2020
5
GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling. 61
32051337 2020
6
Growth of the facultative chemolithoautotroph Ralstonia eutropha on organic waste materials: growth characteristics, redox regulation and hydrogenase activity. 61
31739794 2019
7
An essential role for GLUT5-mediated fructose utilization in exacerbating the malignancy of clear cell renal cell carcinoma. 61
31102011 2019
8
Sucrose Metabolism in Haloarchaea: Reassessment Using Genomics, Proteomics, and Metagenomics. 61
30658981 2019
9
GLUT5 increases fructose utilization in ovarian cancer. 61
31371983 2019
10
SLC2A5 promotes lung adenocarcinoma cell growth and metastasis by enhancing fructose utilization. 61
29531835 2018
11
Ketohexokinase is involved in fructose utilization and promotes tumor progression in glioma. 61
30031605 2018
12
The Fructose-Specific Phosphotransferase System of Klebsiella pneumoniae Is Regulated by Global Regulator CRP and Linked to Virulence and Growth. 61
29844239 2018
13
GLUT5 increases fructose utilization and promotes tumor progression in glioma. 61
29660339 2018
14
Improving Fructose Utilization and Butanol Production by Clostridium acetobutylicum via Extracellular Redox Potential Regulation and Intracellular Metabolite Analysis. 61
28731563 2017
15
Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential. 61
27746145 2016
16
Modeling the effect of cigarette smoke on hexose utilization in spermatocytes. 61
24803506 2015
17
Hexokinase--A limiting factor in lipid production from fructose in Yarrowia lipolytica. 61
25307793 2014
18
Analysis of the transcriptional regulator GlpR, promoter elements, and posttranscriptional processing involved in fructose-induced activation of the phosphoenolpyruvate-dependent sugar phosphotransferase system in Haloferax mediterranei. 61
24334671 2014
19
Phenotypic and metabolic traits of commercial Saccharomyces cerevisiae yeasts. 61
24949272 2014
20
Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization. 61
22822162 2012
21
Addition of IGF-I to storage-cooled boar semen and its effect on sperm quality. 61
21967820 2011
22
Glial-neuronal interactions underlying fructose utilization in rat hippocampal slices. 61
19362122 2009
23
Influence of IGF-I on buffalo (Bubalus bubalis) spermatozoa motility, membrane integrity, lipid peroxidation and fructose uptake in vitro. 61
18804927 2009
24
NMR bioreactor development for live in-situ microbial functional analysis. 61
18314365 2008
25
Iron and carbon metabolism by a mineral-oxidizing Alicyclobacillus-like bacterium. 61
18004545 2008
26
Molecular basis of fructose utilization by the wine yeast Saccharomyces cerevisiae: a mutated HXT3 allele enhances fructose fermentation. 61
17308189 2007
27
A route for fructose utilization by Escherichia coli involving the fucose regulon. 61
17159144 2006
28
Characterization of genes involved in fructose utilization by Lactobacillus fermentum. 61
16741753 2006
29
Bacterial synthesis of PHA block copolymers. 61
16768413 2006
30
Selective utilization of fructose to glucose by Candida magnoliae, an erythritol producer. 61
18563661 2006
31
Selective utilization of fructose to glucose by Candida magnoliae, an erythritol producer. 61
16915695 2006
32
Fructose utilization in Lactococcus lactis as a model for low-GC gram-positive bacteria: its regulator, signal, and DNA-binding site. 61
15901699 2005
33
Sugar import and phytopathogenicity of Spiroplasma citri: glucose and fructose play distinct roles. 61
15672816 2005
34
Glucose and trehalose PTS permeases of Spiroplasma citri probably share a single IIA domain, enabling the spiroplasma to adapt quickly to carbohydrate changes in its environment. 61
12949193 2003
35
In vivo analysis of HPr reveals a fructose-specific phosphotransferase system that confers high-affinity uptake in Streptomyces coelicolor. 61
12533468 2003
36
Spiroplasma citri, a plant pathogenic molligute: relationships with its two hosts, the plant and the leafhopper vector. 61
12730387 2003
37
Comparison between D-[3-3H]- and D-[5-3H]glucose and fructose utilization in pancreatic islets from control and hereditarily diabetic rats. 61
12485609 2002
38
Effect of gallic acid and catechin on Lactobacillus hilgardii 5w growth and metabolism of organic compounds. 61
11559138 2001
39
Routes for fructose utilization by Escherichia coli. 61
11361065 2001
40
Catharanthus roseus genes regulated differentially by mollicute infections. 61
11204786 2001
41
[The multifunctional fructose-specific component of the phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli K12--fruA gene product]. 61
11816114 2001
42
Fructose utilization and phytopathogenicity of Spiroplasma citri. 61
11043476 2000
43
Fructose utilization and pathogenicity of Spiroplasma citri: characterization of the fructose operon. 61
10903438 2000
44
Identification of the up- and down-regulated genes in vancomycin-resistant Staphylococcus aureus strains Mu3 and Mu50 by cDNA differential hybridization method. 61
10708580 2000
45
Hexose metabolism in pancreatic islets: effect of D-glucose upon D-fructose metabolism. 61
10485341 1999
46
Isolation and Properties of Mutants of Zymomonas mobilis Deficient in Sugar Assimilation. 61
16535260 1996
47
Agrobacterium radiobacter and related organisms take up fructose via a binding-protein-dependent active-transport system. 61
7582021 1995
48
Lipid metabolism and substrate oxidation during intravenous fructose administration in cirrhosis. 61
8084292 1994
49
Astaxanthin production by a Phaffia rhodozyma mutant on grape juice. 61
24420942 1994
50
Fructose utilization during exercise in men: rapid conversion of ingested fructose to circulating glucose. 61
8335542 1993

Variations for Fructose Utilization

Expression for Fructose Utilization

Search GEO for disease gene expression data for Fructose Utilization.

Pathways for Fructose Utilization

GO Terms for Fructose Utilization

Sources for Fructose Utilization

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....