MCID: FNG004
MIFTS: 46

Fungal Meningitis

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Fungal Meningitis

MalaCards integrated aliases for Fungal Meningitis:

Name: Fungal Meningitis 12 3 15 17
Meningitis, Fungal 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11608
MeSH 44 D016921
SNOMED-CT 67 24321005
UMLS 70 C0085438

Summaries for Fungal Meningitis

CDC : 3 Fungal meningitis is rare in the United States. It can develop after a fungus spreads from somewhere else in the body to the brain or spinal cord. Some causes of fungal meningitis include Cryptococcus, Histoplasma, Blastomyces, Coccidioides, and Candida.

MalaCards based summary : Fungal Meningitis, also known as meningitis, fungal, is related to cryptococcal meningitis and histoplasmosis. An important gene associated with Fungal Meningitis is IFNG (Interferon Gamma), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Fluconazole and Amphotericin B have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and endothelial, and related phenotypes are endocrine/exocrine gland and hematopoietic system

Disease Ontology : 12 A meningitis that has material basis in a fungal infection.

Wikipedia : 73 Fungal meningitis refers to meningitis caused by a fungal... more...

Related Diseases for Fungal Meningitis

Diseases related to Fungal Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 863)
# Related Disease Score Top Affiliating Genes
1 cryptococcal meningitis 31.9 PLB1 IFNG CSF2 CD4 CCR6
2 histoplasmosis 30.3 TNF IFNG CD4 CCR6
3 multifocal choroiditis 30.2 TNF IL10
4 coccidioidomycosis 30.1 IL17A CYP51A1 CD4 CCR6
5 haemophilus influenzae 30.1 TNF CXCL8
6 vogt-koyanagi-harada disease 30.0 IL17A IL10 IFNG CD8A
7 chronic meningitis 29.9 IL13 CD4 ALB
8 choroiditis 29.8 TNF IL17A IL10 IFNG CD4
9 epidural abscess 29.7 CD4 ALB
10 tuberculous meningitis 29.7 TNF CXCL8 CCL3
11 chronic granulomatous disease 29.6 TNF IL17A IFNG CXCL8 CSF2
12 bacterial meningitis 29.1 TNF IL6 IL17A IL10 IFNG CXCL8
13 central nervous system disease 29.1 TNF IL6 IL17A IFNG CCR6 ALB
14 cellulitis 28.9 TNF IL6 CSF2 CD8A CD4 CCR6
15 sarcoidosis 1 28.6 TNF IL2 IL13 IFNG CD8A CD4
16 endocarditis 28.6 TNF IL6 IL17A IL10 IFNG CXCL8
17 uveitis 28.5 TNF IL6 IL4 IL2 IL17A IL10
18 candidiasis 28.5 TNF IL6 IL4 IL2 IL17A IL10
19 bacterial infectious disease 28.4 TNF IL6 IL17A IL10 IFNG CXCL8
20 meningitis 28.2 TNF IL6 IL4 IL2 IL17A IL13
21 acquired immunodeficiency syndrome 27.9 TNF IL6 IL2 IL10 IFNG CSF2
22 nervous system disease 27.1 TNF IL6 IL4 IL2 IL17A IL10
23 pulmonary disease, chronic obstructive 27.0 TNF IL6 IL4 IL17A IL13 IL10
24 fungal infectious disease 26.5 TNF PLB1 IL6 IL4 IL2 IL17A
25 early yaws 10.4 CD8A CD4
26 panophthalmitis 10.4 IFNG CD4
27 ventilation pneumonitis 10.4 CD8A CD4
28 diffuse infiltrative lymphocytosis syndrome 10.4 CD8A CD4
29 ocular tuberculosis 10.4 IFNG CD4
30 necrotic uveal melanoma 10.4 IFNG CD8A CD4
31 suppurative lymphadenitis 10.4 IFNG CD4 CCR6
32 staphylococcal toxic shock syndrome 10.4 TNF IFNG
33 autoimmune myocarditis 10.4 TNF IFNG
34 latent syphilis 10.4 CD8A CD4
35 polyarticular juvenile idiopathic arthritis 10.4 TNF IFNG
36 adult acute lymphocytic leukemia 10.4 CD8A CD4 CCR6
37 autoimmune lymphoproliferative syndrome, type iia 10.4 CD8A CD4
38 punctate inner choroidopathy 10.3 TNF IL10
39 opportunistic bacterial infectious disease 10.3 TNF IFNG CD4
40 rheumatoid arthritis interstitial lung disease 10.3 TNF CD4
41 nocardiosis 10.3 TNF IFNG CD4
42 cryptosporidiosis 10.3 IFNG CD8A CD4
43 lymph node tuberculosis 10.3 TNF IFNG CD4
44 immunodeficiency 16 10.3 CD8A CD4 CCR6
45 external pathological resorption 10.3 TNF IL6
46 autoimmune glomerulonephritis 10.3 CD8A CD4 CCR6
47 cd40 ligand deficiency 10.3 IFNG CD8A CD4
48 scorpion envenomation 10.3 TNF IL6
49 norwegian scabies 10.3 IL17A CD8A CD4
50 physiological polycythemia 10.3 TNF IL6

Graphical network of the top 20 diseases related to Fungal Meningitis:



Diseases related to Fungal Meningitis

Symptoms & Phenotypes for Fungal Meningitis

MGI Mouse Phenotypes related to Fungal Meningitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.18 ALB CD4 CD8A CSF2 IFNG IL10
2 hematopoietic system MP:0005397 10.18 CCR6 CD4 CD8A CSF2 DYRK3 IFNG
3 digestive/alimentary MP:0005381 10.17 ALB CD4 CYP51A1 IFNG IL10 IL13
4 immune system MP:0005387 10.17 ALB CCR6 CD4 CD8A CSF2 CYP51A1
5 integument MP:0010771 9.96 CD4 CD8A CSF2 IFNG IL10 IL13
6 neoplasm MP:0002006 9.7 ALB CSF2 IFNG IL10 IL2 IL6
7 no phenotypic analysis MP:0003012 9.61 CD4 CYP51A1 IFNG IL10 IL13 IL17A
8 respiratory system MP:0005388 9.28 CSF2 IFNG IL10 IL13 IL17A IL2

Drugs & Therapeutics for Fungal Meningitis

Drugs for Fungal Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
2
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
3
Sertraline Approved Phase 3 79617-96-2 68617
4 Neurotransmitter Agents Phase 3
5 Antidepressive Agents Phase 3
6 Psychotropic Drugs Phase 3
7 Serotonin Uptake Inhibitors Phase 3
8 Liposomal amphotericin B Phase 3
9
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
10
Clotrimazole Approved, Vet_approved 23593-75-1 2812
11
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189
12 Cytochrome P-450 Enzyme Inhibitors
13 Hormone Antagonists
14 Hormones
15 Anti-Infective Agents
16 Antifungal Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis Completed NCT01802385 Phase 3 Sertraline
2 Evaluation of a Public Health Strategy to Improve Survival of HIV Infected Patients Unknown status NCT02334670 Fluconazole

Search NIH Clinical Center for Fungal Meningitis

Cochrane evidence based reviews: meningitis, fungal

Genetic Tests for Fungal Meningitis

Anatomical Context for Fungal Meningitis

MalaCards organs/tissues related to Fungal Meningitis:

40
Spinal Cord, Brain, Endothelial, Eye, Skin, Temporal Lobe

Publications for Fungal Meningitis

Articles related to Fungal Meningitis:

(show top 50) (show all 315)
# Title Authors PMID Year
1
YouTube as a source of patient information for meningitis: A content-quality and audience engagement analysis. 61
33497948 2021
2
A PAS Protein Directs Metabolic Reprogramming during Cryptococcal Adaptation to Hypoxia. 61
33727360 2021
3
Anticapsular and Antifungal Activity of α-Cyperone. 61
33419126 2021
4
First case report of fungal meningitis due to a polypore mushroom Irpex lacteus. 61
33400066 2021
5
Acute Fluctuant Neurological Symptoms in Stable Chronic Cryptococcus gattii Cryptococcomas: A Novel Disease Complication. 61
33394909 2020
6
A combination of receptor mediated transcytosis and photothermal effect promotes BBB permeability and the treatment of meningitis using itraconazole. 61
33231242 2020
7
A cyclin protein governs the infectious and sexual life cycles of Cryptococcus neoformans. 61
33165808 2020
8
Antifungal drugs: An updated review of central nervous system pharmacokinetics. 61
32772402 2020
9
The infection rate of intralesional triamcinolone and the safety of compounding in dermatology for intradermal and subcutaneous injection: A retrospective medical record review. 61
32442698 2020
10
Case Report: Chronic Fungal Meningitis Masquerading as Tubercular Meningitis. 61
32876006 2020
11
Calcium Binding Protein Ncs1 Is Calcineurin Regulated in Cryptococcus neoformans and Essential for Cell Division and Virulence. 61
32907953 2020
12
Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide in Cryptococcus neoformans. 61
32956370 2020
13
Aspergillus fumigatus meningitis in an immunocompetent young woman. 61
32769349 2020
14
An Antivirulence Approach for Preventing Cryptococcus neoformans from Crossing the Blood-Brain Barrier via Novel Natural Product Inhibitors of a Fungal Metalloprotease. 61
32694141 2020
15
Talaromyces (Penicillium) species infection in the central nervous system. 61
32568283 2020
16
Application of Ribosomal Internal Transcribed Spacer 1, Internal Transcribed Spacer 2, and Large-Subunit D1-D2 Regions as the Genetic Markers to Identify Fungi Isolated from Different Environmental Samples: A Molecular Surveillance Study of Public Health Importance. 61
33241369 2020
17
Postcryptococcal Moyamoya Syndrome: Case Report and Review of Literature. 61
32643683 2020
18
Burden of fungal meningitis. 61
32378964 2020
19
Methods for rapid diagnosis of meningitis etiology in adults. 61
32270693 2020
20
A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis. 61
31932719 2020
21
Efficacy of Cerebrospinal Fluid Beta-d-Glucan Diagnostic Testing for Fungal Meningitis: a Systematic Review. 61
31996446 2020
22
Metagenomic Next-Generation Sequencing for Diagnosis of Infectious Encephalitis and Meningitis: A Large, Prospective Case Series of 213 Patients. 61
32211343 2020
23
Rheumatoid arthritis with pachymeningitis - a case presentation and review of the literature. 61
32476685 2020
24
Harnessing the Activity of the Fungal Metalloprotease, Mpr1, To Promote Crossing of Nanocarriers through the Blood-Brain Barrier. 61
31820926 2020
25
A Mechanosensitive Channel Governs Lipid Flippase-Mediated Echinocandin Resistance in Cryptococcus neoformans. 61
31822582 2019
26
Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans. 61
31748248 2019
27
Increase of reactive oxygen species contributes to growth inhibition by fluconazole in Cryptococcus neoformans. 61
31694529 2019
28
Isolated leptomeningeal carcinomatosis and possible fungal meningitis as late sequelae of oesophageal adenocarcinoma. 61
31678919 2019
29
Microbiological diagnosis of tuberculous meningitis: Phenotype to genotype. 61
31939388 2019
30
Concordance between blood and cerebrospinal fluid cultures in meningitis. 61
31303534 2019
31
mSphere of Influence: the Power of Yeast Genetics Still Going Strong! 61
31578250 2019
32
Evaluation of the BioFire FilmArray meningitis/encephalitis panel for the detection of bacteria and yeast in Chinese children. 61
31700873 2019
33
Invasive Cryptococcal Meningitis Presenting as a Skull Base Mass in An Immunocompetent Host: A Case Report. 61
31328082 2019
34
Infantile form of Niemann-Pick disease type C with demyelination: An uncommon feature. 61
31347555 2019
35
Genetic Characterization of Fungi Isolated from Environmental Samples: A Molecular Surveillance Study of Public Health Importance. 61
30728093 2019
36
Fungal Endophthalmitis after Intravitreal Injections of Triamcinolone Contaminated by a Compounding Pharmacy: Five-Year Follow-up of 23 Patients. 61
31014761 2019
37
Concurrent Persistent Cryptococcosis and Mycobacterium avium Complex Infections in a Patient With Human Immunodeficiency Virus. 61
31258430 2019
38
Cryptococcal Meningitis and Anti-virulence Therapeutic Strategies. 61
30863389 2019
39
Epidemiology of fungaemia in Sweden: A nationwide retrospective observational survey. 61
29920785 2018
40
Detection of (1,3)-β-d-Glucan in Cerebrospinal Fluid in Histoplasma Meningitis. 61
30021828 2018
41
Granule-Dependent NK Cell Killing of Cryptococcus Requires Kinesin to Reposition the Cytolytic Machinery for Directed Cytotoxicity. 61
30208325 2018
42
Pandemic 2009 influenza A (H1N1)-associated deaths among children in China: A retrospective analysis. 61
32851255 2018
43
Diagnostic scoring system for tuberculous meningitis among adult patients with non-suppurative and non-bacterial meningitis. 61
29705393 2018
44
Neuroinfections caused by fungi. 61
29785613 2018
45
Novel Treatment of Cryptococcal Meningitis via Neurapheresis Therapy. 61
29788431 2018
46
A Fatal Case of Undiagnosed Candida Meningitis: Role of Computer-assisted Diagnosis. 61
29953039 2018
47
The Practice of Compounding, Associated Compounding Regulations, and the Impact on Dermatologists. 61
30005109 2018
48
Moulds associated with contaminated ocular and injectable drugs: FDA recalls, epidemiology considerations, drug shortages, and aseptic processing. 61
29420758 2018
49
Mould meningitis associated with intravenous drug use. 61
30148056 2018
50
Role of the inositol pyrophosphate multikinase Kcs1 in Cryptococcus inositol metabolism. 61
29357302 2018

Variations for Fungal Meningitis

Expression for Fungal Meningitis

Search GEO for disease gene expression data for Fungal Meningitis.

Pathways for Fungal Meningitis

Pathways related to Fungal Meningitis according to GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.13 TNF IL6 IL4 IL2 IL17A IL13
2
Show member pathways
13.94 TNF IL6 IL4 IL2 IL17A IL13
3
Show member pathways
13.81 TNF IL6 IL4 IL2 IL17A IL13
4
Show member pathways
13.66 TNF IL6 IL4 IL2 IL17A IL13
5
Show member pathways
13.55 TNF IL6 IL4 IL2 IL17A IL13
6
Show member pathways
13.51 TNF IL6 IL4 IL2 IL17A IL13
7
Show member pathways
13.44 TNF IL6 IL4 IL2 IL17A IL13
8
Show member pathways
13.27 TNF IL6 IL2 IL10 IFNG CXCL8
9
Show member pathways
13.01 TNF IL6 CXCL8 CSF2 CD4 CCL3
10 12.92 IL6 IL4 IL2 IL13 IFNG CXCL8
11
Show member pathways
12.85 TNF IL6 IL4 IL2 IL17A IL13
12
Show member pathways
12.75 TNF IL6 IL2 IL17A IL10 IFNG
13
Show member pathways
12.75 TNF IL6 IL4 IL2 IL17A IL13
14
Show member pathways
12.74 TNF IL4 IL2 IL10 IFNG CD4
15 12.73 TNF IL4 IL2 IL17A IL10 IFNG
16
Show member pathways
12.64 TNF IL6 IL4 IL2 IL17A IL10
17
Show member pathways
12.6 TNF IL4 IL2 IFNG CSF2
18
Show member pathways
12.6 IL6 IL4 IL2 IL13 IL10 IFNG
19
Show member pathways
12.52 TNF IL6 IL2 IL10 CXCL8 CCR6
20
Show member pathways
12.51 TNF IL6 IL4 IL17A IL13 IFNG
21
Show member pathways
12.49 TNF IL6 IL4 IL2 IFNG ALB
22 12.45 TNF IL6 IL2 CSF2 CD4
23
Show member pathways
12.41 TNF IL6 IL4 IL2 IL17A IL13
24
Show member pathways
12.32 TNF IL4 IL10 IFNG
25
Show member pathways
12.32 TNF IL6 IL4 IFNG CXCL8
26 12.31 TNF IL6 IL13 IL10 CXCL8
27 12.29 TNF IL6 IL10 IFNG
28 12.29 TNF IL6 IL2 IL10 CXCL8 CD8A
29
Show member pathways
12.27 TNF IL6 IL2 IL10
30 12.21 TNF IL6 IL4 IL2 IFNG CXCL8
31
Show member pathways
12.18 IL4 IL2 IFNG CD8A CD4 CCL3
32 12.17 TNF IL6 IL4 IL17A IL13 IL10
33 12.12 TNF IL6 IL10 IFNG CXCL8 CSF2
34 12.11 TNF IL6 IL4 CSF2 CD8A CD4
35 12.04 IL6 IFNG CXCL8 CCL3
36
Show member pathways
12.04 IL6 IL4 IL17A IFNG CD4
37 12.04 TNF IL6 IL17A IFNG CXCL8 CSF2
38
Show member pathways
11.99 IL6 IL17A CXCL8 CSF2
39
Show member pathways
11.98 TNF IL4 IL2 IFNG CXCL8 CSF2
40 11.97 TNF IL6 IL4 IL2 IL10 IFNG
41 11.95 IL6 IL4 IL2 IL13 IFNG CXCL8
42
Show member pathways
11.9 TNF IL6 IL2 IL17A IL10 IFNG
43 11.89 TNF IL6 IL10 CXCL8
44 11.88 TNF IL6 IL4 IL10 CCR6
45
Show member pathways
11.87 TNF IL6 IL2 IFNG CXCL8 CSF2
46
Show member pathways
11.79 TNF IL2 IFNG CD8A
47 11.79 TNF IL6 IL2 IL10 IFNG CSF2
48 11.78 TNF IL6 IL4 IL13 CXCL8 CSF2
49 11.75 TNF IL6 IL10 IFNG CXCL8
50 11.7 TNF IL6 IL2 IFNG

GO Terms for Fungal Meningitis

Cellular components related to Fungal Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.77 TNF IL6 IL4 IL2 IL17A IL13
2 external side of plasma membrane GO:0009897 9.63 TNF IL17A IL13 CD8A CD4 CCR6
3 extracellular space GO:0005615 9.4 TNF IL6 IL4 IL2 IL17A IL13

Biological processes related to Fungal Meningitis according to GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Name GO ID Score Top Affiliating Genes
1 adaptive immune response GO:0002250 10.11 IL2 IL17A IFNG CD8A CD4
2 negative regulation of apoptotic process GO:0043066 10.1 IL6 IL4 IL2 IL10 DYRK3 ALB
3 inflammatory response GO:0006954 10.02 TNF IL6 IL17A IL13 CXCL8 CCL3
4 positive regulation of protein phosphorylation GO:0001934 9.99 TNF IL2 IFNG CD4
5 positive regulation of gene expression GO:0010628 9.97 TNF IL6 IL4 IL13 IFNG CXCL8
6 negative regulation of inflammatory response GO:0050728 9.95 IL4 IL2 IL13 IL10
7 cellular response to lipopolysaccharide GO:0071222 9.92 TNF IL6 IL10 CXCL8 CSF2
8 regulation of insulin secretion GO:0050796 9.89 TNF IL6 IFNG
9 chemokine-mediated signaling pathway GO:0070098 9.89 CXCL8 CCR6 CCL3
10 positive regulation of inflammatory response GO:0050729 9.89 TNF IL2 IFNG CCL3
11 response to glucocorticoid GO:0051384 9.87 TNF IL6 IL10
12 positive regulation of smooth muscle cell proliferation GO:0048661 9.87 TNF IL6 IL13
13 positive regulation of interleukin-6 production GO:0032755 9.87 TNF IL6 IL17A IFNG
14 positive regulation of cytokine production GO:0001819 9.86 TNF IL10 IFNG
15 positive regulation of tumor necrosis factor production GO:0032760 9.86 IL6 IL17A IFNG CCL3
16 T cell activation GO:0042110 9.84 IL4 CD8A CD4
17 positive regulation of B cell proliferation GO:0030890 9.84 IL4 IL2 IL13
18 positive regulation of T cell proliferation GO:0042102 9.84 IL6 IL4 IL2 CD4
19 positive regulation of chemokine production GO:0032722 9.83 TNF IL6 IFNG
20 positive regulation of interleukin-10 production GO:0032733 9.83 IL6 IL4 IL13
21 negative regulation of endothelial cell apoptotic process GO:2000352 9.82 IL4 IL13 IL10
22 humoral immune response GO:0006959 9.8 TNF IL6 IFNG CCR6
23 positive regulation of JAK-STAT cascade GO:0046427 9.79 TNF IL6 IL10
24 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.77 TNF IL6 IL17A
25 positive regulation of osteoclast differentiation GO:0045672 9.76 TNF IL17A IFNG
26 macrophage differentiation GO:0030225 9.75 IFNG CSF2 CD4
27 microglial cell activation GO:0001774 9.73 TNF IL4 IL13 IFNG
28 negative regulation of T-helper 17 cell differentiation GO:2000320 9.71 IL4 IL2
29 positive regulation of isotype switching to IgG isotypes GO:0048304 9.71 IL4 IL2
30 positive regulation of mast cell degranulation GO:0043306 9.7 IL4 IL13
31 negative regulation of lipid storage GO:0010888 9.7 TNF IL6
32 endothelial cell apoptotic process GO:0072577 9.7 TNF IL10
33 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.7 TNF IL6 IL4 IL2 IL13 IFNG
34 cytokine-mediated signaling pathway GO:0019221 9.7 TNF IL6 IL4 IL2 IL17A IL13
35 vascular endothelial growth factor production GO:0010573 9.69 TNF IL6
36 macrophage activation GO:0042116 9.69 IL4 IL13 CSF2
37 positive regulation of mononuclear cell migration GO:0071677 9.68 TNF IL4
38 negative regulation of cytokine production involved in immune response GO:0002719 9.68 TNF IL10
39 positive regulation of cellular respiration GO:1901857 9.68 IL4 IFNG
40 neuroinflammatory response GO:0150076 9.67 IL4 IFNG
41 type 2 immune response GO:0042092 9.67 IL4 IL10
42 negative regulation of amyloid-beta clearance GO:1900222 9.65 TNF IFNG CYP51A1
43 positive regulation of interleukin-1 beta production GO:0032731 9.65 TNF IL6 IL17A IFNG CCL3
44 negative regulation of complement-dependent cytotoxicity GO:1903660 9.64 IL4 IL13
45 positive regulation of plasma cell differentiation GO:1900100 9.64 IL2 IL10
46 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.63 TNF IFNG
47 regulation of isotype switching GO:0045191 9.63 IL4 IL10
48 positive regulation of MHC class II biosynthetic process GO:0045348 9.63 IL4 IL10 IFNG
49 positive regulation of immunoglobulin production GO:0002639 9.62 IL6 IL2 IL13 IL10
50 positive regulation of vitamin D biosynthetic process GO:0060557 9.61 TNF IFNG

Molecular functions related to Fungal Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.36 TNF IL6 IL4 IL2 IL17A IL13
2 growth factor activity GO:0008083 9.35 IL6 IL4 IL2 IL10 CSF2

Sources for Fungal Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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