MCID: FSR001
MIFTS: 33

Fusariosis

Categories: Blood diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Fusariosis

MalaCards integrated aliases for Fusariosis:

Name: Fusariosis 12 60 45 15 17 74
Fusarium Infection 60

Characteristics:

Orphanet epidemiological data:

60
fusariosis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

Orphanet: 60  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:0050289
MeSH 45 D060585
ICD10 via Orphanet 35 B48.7
UMLS via Orphanet 75 C0276758
Orphanet 60 ORPHA228119
UMLS 74 C0276758

Summaries for Fusariosis

Disease Ontology : 12 An opportunistic mycosis that involves localized or hematogenously disseminated fungal infection by Fusarium solani or Fusarium oxysporum. Skin lesions are seen in neutropenic patients, and indolent cellulitis or soft-tissue necrosis occur in immunocompromised patients at the site of trauma.

MalaCards based summary : Fusariosis, also known as fusarium infection, is related to leukemia and leukemia, acute lymphoblastic. An important gene associated with Fusariosis is TEF (TEF Transcription Factor, PAR BZIP Family Member). The drugs Dexamethasone and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include skin, myeloid and bone, and related phenotype is embryo.

Wikipedia : 77 Fusariosis is an infection seen in neutropenic patients, and is a significant opportunistic pathogen in... more...

Related Diseases for Fusariosis

Graphical network of the top 20 diseases related to Fusariosis:



Diseases related to Fusariosis

Symptoms & Phenotypes for Fusariosis

MGI Mouse Phenotypes related to Fusariosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 8.92 EEF2 IFNG POLR2A SPTAN1

Drugs & Therapeutics for Fusariosis

Drugs for Fusariosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
3 Anti-Inflammatory Agents Phase 3
4 HIV Protease Inhibitors Phase 3
5 Antineoplastic Agents, Hormonal Phase 3
6 Anti-Bacterial Agents Phase 3,Not Applicable
7 Hormones Phase 3,Not Applicable
8 Hormone Antagonists Phase 3,Not Applicable
9 Antiemetics Phase 3
10 Gastrointestinal Agents Phase 3
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Not Applicable
12 glucocorticoids Phase 3
13 Autonomic Agents Phase 3
14 BB 1101 Phase 3
15 Anti-Infective Agents Phase 3,Not Applicable
16
protease inhibitors Phase 3
17 Peripheral Nervous System Agents Phase 3
18
Voriconazole Approved, Investigational Not Applicable 137234-62-9 71616
19
Posaconazole Approved, Investigational, Vet_approved Not Applicable 171228-49-2 147912
20
Miconazole Approved, Investigational, Vet_approved Not Applicable 22916-47-8 4189
21
Caspofungin Approved Not Applicable 162808-62-0, 179463-17-3 2826718 468682
22 Cytochrome P-450 CYP3A Inhibitors Not Applicable
23 Antiprotozoal Agents Not Applicable
24 Steroid Synthesis Inhibitors Not Applicable
25 Cytochrome P-450 Enzyme Inhibitors Not Applicable
26 Antiparasitic Agents Not Applicable
27 Antifungal Agents Not Applicable
28 Cytochrome P-450 CYP2C9 Inhibitors Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study) Completed NCT00627393 Phase 3 Standard antimicrobial therapy;G-CSF/dexamethasone
2 Fusariosis in Solid-Organ Transplant Recipients Completed NCT00518778
3 Anti-mold Azole in the Prophylaxis for Invasive Fusariosis Completed NCT02714504 Not Applicable Voriconazole or posaconazole
4 Fusarium Keratitits in Spain 2012 to 2014 Completed NCT02984904
5 Sautour PHRC IR 2008 Completed NCT02859831
6 Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients Terminated NCT00982540 Not Applicable caspofungin as preemptive antifungal therapy

Search NIH Clinical Center for Fusariosis

Cochrane evidence based reviews: fusariosis

Genetic Tests for Fusariosis

Anatomical Context for Fusariosis

MalaCards organs/tissues related to Fusariosis:

42
Skin, Myeloid, Bone, Bone Marrow, Lung, T Cells, Testes

Publications for Fusariosis

Articles related to Fusariosis:

(show top 50) (show all 237)
# Title Authors Year
1
Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient. ( 31049455 )
2019
2
Fusariosis in a Captive South American Sea Lion (Otaria flavescens): A Case Report. ( 29761326 )
2019
3
Outcomes of patients with invasive fusariosis who undergo further immunosuppressive treatments, is there a role for secondary prophylaxis? ( 30720902 )
2019
4
Endobronchial fusariosis in a child following bilateral lung transplant. ( 30723665 )
2019
5
Invasive fusariosis masquerading as extramedullary disease in rapidly progressive acute lymphoblastic leukemia. ( 30900813 )
2019
6
Performance of 1,3-beta-D-glucan in the Diagnosis and Monitoring of Invasive Fusariosis. ( 31025423 )
2019
7
Unraveling the ecology and epidemiology of an emerging fungal disease, sea turtle egg fusariosis (STEF). ( 31095638 )
2019
8
Fusarium infection-induced partial failure of free anterolateral thigh musculocutaneous flap: Case report. ( 31007923 )
2019
9
Invasive mould disease in haematologic patients: comparison between fusariosis and aspergillosis. ( 29787890 )
2018
10
Lipopeptides produced by Bacillus subtilis as new biocontrol products against fusariosis in ornamental plants. ( 28528498 )
2018
11
Current antifungal treatment of fusariosis. ( 28705676 )
2018
12
Disseminated cutaneous fusariosis in human immunodeficiency virus-infected patient and dramatic response with oral itraconazole. ( 29327700 )
2018
13
Disseminated fusariosis emerged from prolonged local genital infection after cord blood transplantation. ( 29373264 )
2018
14
Successful Combination Therapy of Liposomal Amphotericin B and Caspofungin for Disseminated Fusariosis in a Pediatric Patient With Acute Lymphoblastic Leukemia. ( 29438132 )
2018
15
Fluorine-18-fluorodeoxyglucose PET/CT in hematopoietic stem cell transplant patients with fusariosis: initial findings of a case series review. ( 29652746 )
2018
16
Airborne transmission of invasive fusariosis in patients with hematologic malignancies. ( 29698435 )
2018
17
Recent Advances in the Treatment of Scedosporiosis and Fusariosis. ( 29912161 )
2018
18
Tackling maize fusariosis: in search of Fusarium graminearum biosuppressors. ( 29934785 )
2018
19
Disseminated fusariosis with cutaneous involvement in hematologic malignancies: report of six cases with high mortality rate. ( 30156626 )
2018
20
Lack of correlation of ECV and outcome in an in vivo murine model of systemic fusariosis. ( 30201117 )
2018
21
Fatal Fusarium infection manifesting as osteomyelitis following previous treatment with amphotericin B in a multi-visceral transplant: Case report and review of Fusarium infections in solid organ transplantation. ( 29512240 )
2018
22
Redox imbalance contributed differently to membrane damage of cucumber leaves under water stress and Fusarium infection. ( 30080601 )
2018
23
Phenolic Profile and Susceptibility to Fusarium Infection of Pigmented Maize Cultivars. ( 30154815 )
2018
24
Fusarium Infection in a Kidney Transplant Recipient Successfully Treated with Voriconazole. ( 30159184 )
2018
25
Melanization of Fusarium keratoplasticum (F. solani Species Complex) During Disseminated Fusariosis in a Patient with Acute Leukemia. ( 28616680 )
2017
26
Disseminated Fusariosis in Immunocompromised Children-Analysis of Recent Cases Identified in the Global Fungiscope Registry. ( 27846057 )
2017
27
Breakthrough fusariosis presenting initially with pyomyositis. ( 27914686 )
2017
28
Detection of Fusarium-specific T cells in hematologic patients with invasive fusariosis. ( 28017824 )
2017
29
A rare case of subcutaneous fusariosis in an immunocompetent patient. ( 28166614 )
2017
30
Epidemiological Study of Fusarium Species Causing Invasive and Superficial Fusariosis in Japan. ( 28250364 )
2017
31
A Fortuitous Turn of Evidence in an Elderly Female - A Case of Pulmonary Fusariosis. ( 28384871 )
2017
32
The Use of FDG PET-CT Imaging for the Assessment of Early Antifungal Treatment Response in Disseminated Fusariosis. ( 28481795 )
2017
33
Sudden blindness as an initial manifestation of localized fusariosis in ethmoid sinus and optic nerve. ( 28752393 )
2017
34
Enucleation Caused by Fusarium Infection in a Child With Toxic Epidermal Necrolysis. ( 27741094 )
2017
35
Disseminated fusarium infection after ibrutinib therapy in chronic lymphocytic leukaemia. ( 28184982 )
2017
36
Eosinophil fungal rhinosinusitis caused by Fusarium infection secondary to odontogenic maxillary sinus disease: when collaboration between otolaryngologist and allergologist leads to the correct diagnosis and therapy. ( 28497678 )
2017
37
Fusarium infection causes genotoxic disorders and antioxidant-based damages in Orobanche spp. ( 28602401 )
2017
38
Fusarium Infection Causes Phenolic Accumulations and Hormonal Disorders in Orobanche spp. ( 29151642 )
2017
39
Interplay of neuronal and non-neuronal genes regulates intestinal DAF-16-mediated immune response during Fusarium infection of Caenorhabditis elegans. ( 29152379 )
2017
40
Combating Fusarium Infection Using Bacillus-Based Antimicrobials. ( 29165349 )
2017
41
Discrimination of Aspergillosis, Mucormycosis, Fusariosis, and Scedosporiosis in Formalin-Fixed Paraffin-Embedded Tissue Specimens by Use of Multiple Real-Time Quantitative PCR Assays. ( 27605714 )
2016
42
The current treatment landscape: other fungal diseases (cryptococcosis, fusariosis and mucormycosis). ( 27880667 )
2016
43
Disseminated fusariosis with endophthalmitis after skin trauma in acute lymphoblastic leukaemia. ( 26395131 )
2016
44
Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature. ( 26661324 )
2016
45
Fusariosis in a Patient with Acute Myeloid Leukemia: A Case Report and Review of the Literature. ( 27008433 )
2016
46
New Insights for Diagnosis of Pineapple Fusariosis by MALDI-TOF MS Technique. ( 27117163 )
2016
47
Fusarium musae infected banana fruits as potential source of human fusariosis: May occur more frequently than we might think and hypotheses about infection. ( 27195070 )
2016
48
Successful Treatment of Disseminated Fusariosis with the Combination of Voriconazole and Liposomal Amphotericin B. ( 27311328 )
2016
49
Antimold Prophylaxis May Reduce the Risk of Invasive Fusariosis in Hematologic Patients with Superficial Skin Lesions with Positive Culture for Fusarium. ( 27671065 )
2016
50
Banana fruits affected by Fusarium post-harvest disease as source of human fusariosis. ( 27682849 )
2016

Variations for Fusariosis

Expression for Fusariosis

Search GEO for disease gene expression data for Fusariosis.

Pathways for Fusariosis

GO Terms for Fusariosis

Sources for Fusariosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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